EP1539188A4

Nucleoside derivatives as inhibitors of rna-dependent rna viral polymerase

Abstract

This record has no abstract on file.

EP1539188A4, drawing sheet 1 — Sheet 1 of 218

Term

Term ended

Projected expiry passed 18 January 2022, 4.7 years ago.

Parties

Owner: MERCK SHARP & DOHME CORP
Applicants: Merck & Co., Inc.
ISIS PHARMACEUTICALS, INC.
Inventors: CARROLL, Steven, S., Rahway, NJ 07065-0907, United States of America
LAFEMINA, Robert, L., Rahway, NJ 07065-0907, United States of America
HALL, Dawn, L., Rahway, NJ 07065-0907, United States of America
HIMMELBERGER, Amy, L., Rahway, NJ 07065-0907, United States of America
and 14 more inventorsShow fewer
KUO, Lawrence, C., Rahway, NJ 07065-0907, United States of America
MACCOSS, Malcolm, Rahway, NJ 07065-0907, United States of America
OLSEN, David, B., Rahway, NJ 07065-0907, United States of America
RUTKOWSKI, Carrie, A., Rahway, NJ 07065-0907, United States of America
TOMASSINI, Joanne, E., Rahway, NJ 07065-0907, United States of America
AN, Haoyun, Carlsbad, CA 92008, United States of America
BHAT, Balkrishen, Carlsbad, CA 92008, United States of America
BHAT, Neelima, Carlsbad, CA 92008, United States of America
COOK, Phillip, Dan, Carlsbad, CA 92008, United States of America
ELDRUP, Anne, B., Carlsbad, CA 92008, United States of America
GUINOSSO, Charles, J., Carlsbad, CA 92008, United States of America
PRHAVC, Marija, Carlsbad, CA 92008, United States of America
PRAKASH, Thazha, P., Carlsbad, CA 92008, United States of America
PETRINI, Guido, I-28066 Galliate (Novara), Italy

Examination

Examiner: Alfaro Faus, Ignacio
Agent: Horgan, James Michael Frederic

Reach

Cites: 2 earlier patents, 3 other works⁠
Family: 98 members in 43 offices⁠US16EP10JP5CA4HU4WO4NO3AT2+35

Classification

CPC: C07H19/14C07H19/16A61K31/7056A61K31/7076C07D473/00C07D487/04+14 more
IPC: A61K31 519A61K31 70A61K31 7052A61K31 706C07D487 04A61K31 7064+28 more

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Every citation, both ways

Citations
Document	Relation	Office	Category	Cited during	Relevant claims
WO02069903A2	Cites	World Intellectual Property Organization (WIPO)	E	Search report	1
WO02069903A	Cites	World Intellectual Property Organization (WIPO)	–	–	–
SMEE, DONALD F. ET AL: "Novel pyrazolo[3,4-d]pyrimidine nucleoside analog with broad-spectrum antiviral activity", ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 31(10), 1535-41 CODEN: AMACCQ; ISSN: 0066-4804, 1987, XP002540074	Non-patent	–	–	Search report	–
DEE NORD L ET AL: "Inhibition of orotidylate decarboxylase by 4(5H)-oxo-1-beta-d-ribofur anosylpyrazolo[3,4-d] pyrimidine-3-thiocarboxamide (APR-TC) in B lymphoblasts - Activation by adenosine kinase", BIOCHEMICAL PHARMACOLOGY, PERGAMON, OXFORD, GB, vol. 37, no. 24, 15 December 1988 (1988-12-15), pages 4697 - 4705, XP023731885, ISSN: 0006-2952, [retrieved on 19881215]	Non-patent	–	–	Search report	–
See also references of WO 02057425A2	Non-patent	–	–	Search report	–

98 members in 43 offices

This recordMember, by publication datePriority claim33 more offices are in the list below

Priority claims9

Priority claims
Document	Office	Kind	Date
263313P	United States of America	–	2001-01-22
26331301	United States of America	P	2001-01-22
282069P	United States of America	–	2001-04-06
28206901	United States of America	P	2001-04-06
299320P	United States of America	–	2001-06-19
29932001	United States of America	P	2001-06-19
344528P	United States of America	–	2001-10-25
34452801	United States of America	P	2001-10-25
0201531	United States of America	W	2002-01-18

Members98

Family members, oldest first
Document	Office	Kind
CA2433878A1	Canada	A1	2002-07-25
DZ3487A1	Algeria	A1	2002-07-25
WO02057287A2	World Intellectual Property Organization (WIPO)	A2	2002-07-25
WO02057425A2	World Intellectual Property Organization (WIPO)	A2	2002-07-25
CA2434386A1	Canada	A1	2002-08-25
PE20020823A1	Peru	A1	2002-09-11
US2002147160A1	United States of America	A1	2002-10-10
WO02057287A3	World Intellectual Property Organization (WIPO)	A3	2002-10-10
IS6860A	Iceland	A	2003-06-25
NO20033289D0	Norway	D0	2003-07-21
ECSP034699A	Ecuador	A	2003-08-29
NO20033289L	Norway	L	2003-09-19
EE200300338A	Estonia	A	2003-10-15
EP1355916A2	European Patent Office (EPO)	A2	2003-10-29
SK9322003A3	Slovakia	A3	2003-12-02
IL156641A0	Israel	A0	2004-01-04
KR20040002854A	Republic of Korea	A	2004-01-07
BR0206614A	Brazil	A	2004-02-17
BR0206614A	Brazil	A	2004-02-17
US2004067901A1	United States of America	A1	2004-04-08
CZ20032005A3	Czechia	A3	2004-04-14
US2004072788A1	United States of America	A1	2004-04-15
EA200300819A1	Eurasian Patent Organization (EAPO)	A1	2004-04-29
CN1498221A	China	A	2004-05-19
US2004110717A1	United States of America	A1	2004-06-10
HU0400726A2	Hungary	A2	2004-06-28
HUP0400726A2	Hungary	A2	2004-06-28
AR035736A1	Argentina	A1	2004-07-07
JP2004520367A	Japan	A	2004-07-08
ZA200305078B	South Africa	B	2004-07-28
US6777395B2	United States of America	B2	2004-08-17
BG108000A	Bulgaria	A	2004-08-31
JP2004532184A	Japan	A	2004-10-21
PL363216A1	Poland	A1	2004-11-15
MXPA03006514A	Mexico	A	2004-12-02
MXPA03006514A	Mexico	A	2004-12-02
NZ526703A	New Zealand	A	2004-12-24
HK1066014A	Hong Kong, China	A	2005-03-11
HK1066014A1	Hong Kong, China	A1	2005-03-11
WO02057425A3	World Intellectual Property Organization (WIPO)	A3	2005-04-21
EP1539188A2	European Patent Office (EPO)	A2	2005-06-15
HRP20030565A2	Croatia	A2	2005-06-30
GEP20053601B	Georgia	B	2005-08-10
JO2318B1	Jordan	B1	2005-09-12
UA73843C2	Ukraine	C2	2005-09-15
US2005272676A1	United States of America	A1	2005-12-08
YU56903A	Yugoslavia, later Serbia and Montenegro (until 2006)	A	2006-03-03
AU2002243791B2	Australia	B2	2006-06-29
CN1267446C	China	C	2006-08-02
TWI261056B	Taiwan Province of China	B	2006-09-01
US7105499B2	United States of America	B2	2006-09-12
US2006205686A1	United States of America	A1	2006-09-14
AU2002243600B2	Australia	B2	2006-09-28
EP1707571A1	European Patent Office (EPO)	A1	2006-10-04
US7125855B2	United States of America	B2	2006-10-24
EA007491B1	Eurasian Patent Organization (EAPO)	B1	2006-10-27
US2006264390A1	United States of America	A1	2006-11-23
CA2434386C	Canada	C	2006-12-05
EP1355916B1	European Patent Office (EPO)	B1	2007-01-10
DE60217465D1	Germany	D1	2007-02-22
US7202224B2	United States of America	B2	2007-04-10
PT1355916E	Portugal	E	2007-04-30
SI1355916T1	Slovenia	T1	2007-04-30
DK1355916T3	Denmark	T3	2007-05-07
JP3914156B2	Japan	B2	2007-05-16
HU0400726A3	Hungary	A3	2007-05-29
HUP0400726A3	Hungary	A3	2007-05-29
ES2278009T3	Spain	T3	2007-08-01
JP2007224045A	Japan	A	2007-09-06
DE60217465T2	Germany	T2	2007-10-18
US2007275912A1	United States of America	A1	2007-11-29
MY134070A	Malaysia	A	2007-11-30
KR100828453B1	Republic of Korea	B1	2008-05-13
IS2449B	Iceland	B	2008-11-15
CA2433878C	Canada	C	2008-11-25
NO326431B1	Norway	B1	2008-12-08
SK286630B6	Slovakia	B6	2009-02-05
RS50236B	Serbia	B	2009-07-15
EG24465A	Egypt	A	2009-07-27
EP1539188A4This record	European Patent Office (EPO)	A4	2009-09-30
PL207405B1	Poland	B1	2010-12-31
EP2360166A1	European Patent Office (EPO)	A1	2011-08-24
EP1707571B1	European Patent Office (EPO)	B1	2011-09-28
AT526339T	Austria	T	2011-10-15
ATE526339T1	Austria	T1	2011-10-15
EP2399588A1	European Patent Office (EPO)	A1	2011-12-28
HRP20030565B1	Croatia	B1	2011-12-31
BG66207B1	Bulgaria	B1	2012-04-30
JP4931683B2	Japan	B2	2012-05-16
US2012165515A1	United States of America	A1	2012-06-28
US8481712B2	United States of America	B2	2013-07-09
EE05709B1	Estonia	B1	2014-04-15
CY1109012T1	Cyprus	T1	2014-07-02
US2014309412A1	United States of America	A1	2014-10-16
EP1539188B1	European Patent Office (EPO)	B1	2015-01-07
ES2532836T3	Spain	T3	2015-04-01
US2017183373A1	United States of America	A1	2017-06-29
EP2399588B1	European Patent Office (EPO)	B1	2020-04-29

130 legal events, as 10 offices reported them to INPADOC

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Events

Legal events, newest first
	Event	Code	Office
2022-04-29	Lapsed in a contracting state [announced via postgrant information from national office to epo]LapsedPG25	PG25	EP
2022-02-09	Patent expired after termination of 20 yearsExpiredPE20	PE20	GB
2022-01-18	Expiry of rightR071	R071	DE
2021-08-31	Lapsed in a contracting state [announced via postgrant information from national office to epo]LapsedPG25	PG25	EP
2021-06-03	Announcement of lapse in spainLapsedFD2A	FD2A	ES
2021-05-31	Annual fee paid to national office [announced via postgrant information from national office to epo]GrantedPGFP	PGFP	EP
2021-01-29	Lapsed in a contracting state [announced via postgrant information from national office to epo]LapsedPG25	PG25	EP
2021-01-29	Annual fee paid to national office [announced via postgrant information from national office to epo]GrantedPGFP	PGFP	EP
2021-01-29	Annual fee paid to national office [announced via postgrant information from national office to epo]GrantedPGFP	PGFP	EP
2019-04-30	Annual fee paid to national office [announced via postgrant information from national office to epo]GrantedPGFP	PGFP	EP
2019-04-30	Annual fee paid to national office [announced via postgrant information from national office to epo]GrantedPGFP	PGFP	EP
2017-12-20	Fee paymentPLFP	PLFP	FR
2017-11-30	Lapsed in a contracting state [announced via postgrant information from national office to epo]LapsedPG25	PG25	EP
2017-08-31	Lapsed in a contracting state [announced via postgrant information from national office to epo]LapsedPG25	PG25	EP
2017-07-31	Lapsed in a contracting state [announced via postgrant information from national office to epo]LapsedPG25	PG25	EP
2017-06-30	Lapsed in a contracting state [announced via postgrant information from national office to epo]LapsedPG25	PG25	EP
2017-01-03	Fee paymentPLFP	PLFP	FR
2016-05-31	Lapsed in a contracting state [announced via postgrant information from national office to epo]LapsedPG25	PG25	EP
2016-01-29	Lapsed in a contracting state [announced via postgrant information from national office to epo]LapsedPG25	PG25	EP
2015-12-30	Fee paymentPLFP	PLFP	FR
2015-12-16	No opposition filedOpposition26N	26N	EP
2015-11-13	No opposition filed within time limitOppositionORIGINAL CODE: 0009261PLBE	PLBE	EP
2015-11-13	Information on the status of an ep patent application or granted ep patentGrantedSTATUS: NO OPPOSITION FILED WITHIN TIME LIMITSTAA	STAA	EP
2015-11-04	Patent lapsedLapsedMM4A	MM4A	IE
2015-10-30	Lapsed in a contracting state [announced via postgrant information from national office to epo]LapsedPG25	PG25	EP
2015-10-30	Lapsed in a contracting state [announced via postgrant information from national office to epo]LapsedPG25	PG25	EP
2015-10-30	Lapsed in a contracting state [announced via postgrant information from national office to epo]LapsedPG25	PG25	EP
2015-10-30	Lapsed in a contracting state [announced via postgrant information from national office to epo]LapsedPG25	PG25	EP
2015-10-08	No opposition filed against granted patent, or epo opposition proceedings concluded without decisionGrantedR097	R097	DE
2015-08-31	Lapsed in a contracting state [announced via postgrant information from national office to epo]LapsedPG25	PG25	EP
2015-08-31	Lapsed in a contracting state [announced via postgrant information from national office to epo]LapsedPG25	PG25	EP
2015-08-31	Lapsed in a contracting state [announced via postgrant information from national office to epo]LapsedPG25	PG25	EP
2015-08-28	Patent ceasedCeasedPL	PL	CH
2015-07-31	Lapsed in a contracting state [announced via postgrant information from national office to epo]LapsedPG25	PG25	EP
2015-07-31	Lapsed in a contracting state [announced via postgrant information from national office to epo]LapsedPG25	PG25	EP
2015-06-30	Lapsed in a contracting state [announced via postgrant information from national office to epo]LapsedPG25	PG25	EP
2015-06-25	Invalidation of extension of european patentsMG9D	MG9D	LT
2015-06-15	Deletion acc. to par. 5 (withdrawal of the translation of the ep patent)MK05	MK05	AT
2015-05-20	Discontinued in the netherlands as no translation has been filedVDEP	VDEP	NL
2015-04-01	Definitive protectionFG2A	FG2A	ES
2015-02-19	Dpma publication of mentioned ep patent grantGrantedR096	R096	DE
2015-02-15	Reference to at number (ep patent validated in austria)REF	REF	AT
2015-01-28	European patents granted designating irelandGrantedFG4D	FG4D	IE
2015-01-15	European patent takes effect as a national patent in ch/liEP	EP	CH
2015-01-07	Designated contracting statesAK	AK	EP
2015-01-07	Request for extension of the european patentAX	AX	EP
2015-01-07	European patent grantedGrantedFG4D	FG4D	GB
2014-12-12	(expected) grantORIGINAL CODE: 0009210GRAA	GRAA	EP
2014-11-28	Grant fee paidORIGINAL CODE: EPIDOSNIGR3GRAS	GRAS	EP
2014-08-20	Intention to grant announcedINTG	INTG	EP
2014-08-20	Information on inventor provided before grant (corrected)RIN1	RIN1	EP
2014-08-20	Information on inventor provided before grant (corrected)RIN1	RIN1	EP
2014-08-20	Information on inventor provided before grant (corrected)RIN1	RIN1	EP
2014-08-20	Information on inventor provided before grant (corrected)RIN1	RIN1	EP
2014-08-20	Information on inventor provided before grant (corrected)RIN1	RIN1	EP
2014-08-20	Information on inventor provided before grant (corrected)RIN1	RIN1	EP
2014-08-20	Information on inventor provided before grant (corrected)RIN1	RIN1	EP
2014-08-20	Information on inventor provided before grant (corrected)RIN1	RIN1	EP
2014-08-20	Information on inventor provided before grant (corrected)RIN1	RIN1	EP
2014-08-20	Information on inventor provided before grant (corrected)RIN1	RIN1	EP
2014-08-20	Information on inventor provided before grant (corrected)RIN1	RIN1	EP
2014-08-20	Information on inventor provided before grant (corrected)RIN1	RIN1	EP
2014-08-20	Information on inventor provided before grant (corrected)RIN1	RIN1	EP
2014-08-20	Information on inventor provided before grant (corrected)RIN1	RIN1	EP
2014-08-20	Information on inventor provided before grant (corrected)RIN1	RIN1	EP
2014-08-20	Information on inventor provided before grant (corrected)RIN1	RIN1	EP
2014-08-20	Information on inventor provided before grant (corrected)RIN1	RIN1	EP
2014-07-21	Despatch of communication of intention to grant a patentORIGINAL CODE: EPIDOSNIGR1GRAP	GRAP	EP
2012-08-15	Party data changed (applicant data changed or rights of an application transferred)RAP1	RAP1	EP
2012-08-15	Party data changed (applicant data changed or rights of an application transferred)RAP1	RAP1	EP
2012-08-08	Party data changed (applicant data changed or rights of an application transferred)RAP1	RAP1	EP
2012-08-08	Party data changed (applicant data changed or rights of an application transferred)RAP1	RAP1	EP
2011-12-14	Information on inventor provided before grant (corrected)RIN1	RIN1	EP
2011-12-14	Information on inventor provided before grant (corrected)RIN1	RIN1	EP
2011-12-14	Information on inventor provided before grant (corrected)RIN1	RIN1	EP
2011-12-14	Information on inventor provided before grant (corrected)RIN1	RIN1	EP
2011-12-14	Information on inventor provided before grant (corrected)RIN1	RIN1	EP
2011-12-14	Information on inventor provided before grant (corrected)RIN1	RIN1	EP
2011-12-14	Information on inventor provided before grant (corrected)RIN1	RIN1	EP
2011-12-14	Information on inventor provided before grant (corrected)RIN1	RIN1	EP
2011-12-14	Information on inventor provided before grant (corrected)RIN1	RIN1	EP
2011-12-14	Information on inventor provided before grant (corrected)RIN1	RIN1	EP
2011-12-14	Information on inventor provided before grant (corrected)RIN1	RIN1	EP
2011-12-14	Information on inventor provided before grant (corrected)RIN1	RIN1	EP
2011-12-14	Information on inventor provided before grant (corrected)RIN1	RIN1	EP
2011-12-14	Information on inventor provided before grant (corrected)RIN1	RIN1	EP
2011-12-14	Information on inventor provided before grant (corrected)RIN1	RIN1	EP
2011-12-14	Information on inventor provided before grant (corrected)RIN1	RIN1	EP
2011-12-14	Information on inventor provided before grant (corrected)RIN1	RIN1	EP
2011-09-28	Party data changed (applicant data changed or rights of an application transferred)RAP1	RAP1	EP
2011-09-28	Party data changed (applicant data changed or rights of an application transferred)RAP1	RAP1	EP
2010-07-28	First examination report despatched17Q	17Q	EP
2010-03-10	Party data changed (applicant data changed or rights of an application transferred)RAP1	RAP1	EP
2010-03-10	Party data changed (applicant data changed or rights of an application transferred)RAP1	RAP1	EP
2009-09-30	Supplementary search report drawn up and despatchedA4	A4	EP
2009-09-16	Information provided on ipc code assigned before grantRIC1	RIC1	EP
2009-09-16	Information provided on ipc code assigned before grantRIC1	RIC1	EP
2009-09-16	Information provided on ipc code assigned before grantRIC1	RIC1	EP
2009-09-16	Information provided on ipc code assigned before grantRIC1	RIC1	EP
2006-03-01	Information on inventor provided before grant (corrected)RIN1	RIN1	EP

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