AT526339T

Nucleoside derivatives as inhibitors of rna-dependent rna viral polymerase

Abstract

The present invention provides a pharmaceutically acceptable salt of a compound of formula (I) wherein R1 is, among other things, a C2-C4 alkenyl group, R2 is, among others, hydrogen, R3 and R4 are, independently of one another, hydrogen, R5 is, among other things, hydrogen, R6 is, among others, hydrogen, R9 is, among others, hydrogen, R10 and R11 are, independently of one another, hydrogen, hydroxy and halo. The present invention also provides pharmaceutical compositions comprising a compound of the invention and a pharmaceutically acceptable carrier, and the use of the present invention for the preparation of a medicament for the preparation of a RNA-dependent RNA virus polymerase inhibitor or for inhibiting RNA-dependent RNA virus replication. HE

Term

Term ended

Expired 18 January 2022, 4.7 years ago.

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Priority claims
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26331301United States of AmericaP
28206901United States of AmericaP
29932001United States of AmericaP
34452801United States of AmericaP

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