EP1518864A3
Antibody against rhesus D
Abstract
The present invention relates to a monoclonal antibody having at its glycosylation site (Asn 297) of Fcγ glycan structures of the biantennary type, with short chains, low sialylation, mannoses and GIcNAc of the non-intermediate terminal attachment point and a rate of less than 65% fucose.
Term
Term ended
Projected expiry passed 12 April 2021, 5.5 years ago.
- Priority
- Filed
- Published
- Projected expiry
- Today
Every citation, both ways
| Document | Relation | Office | Category | Cited during | Relevant claims |
|---|---|---|---|---|---|
| WO9954342A1 | Cites | World Intellectual Property Organization (WIPO) | X | Search report | 1-10 |
| WRIGHT A ET AL: "Effect of glycosylation on antibody function: implications for genetic engineering", TRENDS IN BIOTECHNOLOGY, ELSEVIER PUBLICATIONS, CAMBRIDGE, GB, vol. 15, no. 1, 1 January 1997 (1997-01-01), pages 26 - 32, XP004016809, ISSN: 0167-7799 | Non-patent | – | – | Search report | – |
| KLEIN PHILIPPE ET AL: "Human recombinant anti-Rh(D) monoclonal antibodies: Improvement of biological properties by in vitro class-switch.", HUMAN ANTIBODIES, vol. 8, no. 1, 1997, pages 17 - 25, XP001015726, ISSN: 1093-2607 | Non-patent | – | – | Search report | – |
| HADLEY, A. G. ET AL: "The functional activity of Fc.gamma.RII and Fc.gamma.RIII on subsets of human lymphocytes", IMMUNOLOGY, vol. 76, no. 3, 1992, pages 446 - 451, XP001015733 | Non-patent | – | – | Search report | – |
| PATERSON T ET AL: "Variation in IgG1 heavy chain allotype does not contribute to differences in biological activity of two human anti-Rhesus (D) monoclonal antibodies", IMMUNOTECHNOLOGY,NL,ELSEVIER SCIENCE PUBLISHERS BV, vol. 4, no. 1, 1 June 1998 (1998-06-01), pages 37 - 47, XP004127385, ISSN: 1380-2933 | Non-patent | – | – | Search report | – |
89 members in 11 offices
Priority claims4
| Document | Office | Kind | Date |
|---|---|---|---|
| 0004685 | France | – | |
| 0004685 | France | A | |
| 01927974 | European Patent Office (EPO) | A | |
| 0101127 | France | W |
Members89
| Document | Office | Kind | |
|---|---|---|---|
| US934812A | United States of America | A | |
| US939085A | United States of America | A | |
| US960637A | United States of America | A | |
| CA2406033A1 | Canada | A1 | |
| WO0177181A2 | World Intellectual Property Organization (WIPO) | A2 | |
| FR2807767A1 | France | A1 | |
| AU2001254858B2 | Australia | B2 | |
| AU5485801A | Australia | A | |
| WO0177181A3 | World Intellectual Property Organization (WIPO) | A3 | |
| EP1272527A2 | European Patent Office (EPO) | A2 | |
| US2003175969A1 | United States of America | A1 | |
| JP2003534781A | Japan | A | |
| FR2807767B1 | France | B1 | |
| EP1518864A2 | European Patent Office (EPO) | A2 | |
| US2005249722A1 | United States of America | A1 | |
| US2007009522A1 | United States of America | A1 | |
| AU2007202060A1 | Australia | A1 | |
| EP1272527B1 | European Patent Office (EPO) | B1 | |
| AT419276T | Austria | T | |
| ATE419276T2 | Austria | T2 | |
| DE60137210D1 | Germany | D1 | |
| DK1272527T3 | Denmark | T3 | |
| ES2320412T3 | Spain | T3 | |
| US7541029B2 | United States of America | B2 | |
| EP1518864A3This record | European Patent Office (EPO) | A3 | |
| US7579170B2 | United States of America | B2 | |
| AU2007202060B2 | Australia | B2 | |
| AU2010257417A1 | Australia | A1 | |
| US2011052571A1 | United States of America | A1 | |
| US2011059072A1 | United States of America | A1 | |
| US2011059073A1 | United States of America | A1 | |
| US7931895B2 | United States of America | B2 | |
| EP2341078A2 | European Patent Office (EPO) | A2 | |
| US2011223658A1 | United States of America | A1 | |
| EP2341078A3 | European Patent Office (EPO) | A3 | |
| US8124078B2 | United States of America | B2 | |
| AU2010257417B2 | Australia | B2 | |
| US8153124B2 | United States of America | B2 | |
| US8178093B2 | United States of America | B2 | |
| AU2012203957A1 | Australia | A1 | |
| JP2012191938A | Japan | A | |
| JP2012193184A | Japan | A | |
| JP2012193185A | Japan | A | |
| US2012258096A1 | United States of America | A1 | |
| US2012259095A1 | United States of America | A1 | |
| US8357370B2 | United States of America | B2 | |
| US8409572B2 | United States of America | B2 | |
| JP5192625B2 | Japan | B2 | |
| JP2013155198A | Japan | A | |
| US8685725B2 | United States of America | B2 | |
| AU2012203957B2 | Australia | B2 | |
| CA2406033C | Canada | C | |
| US2014162356A1 | United States of America | A1 | |
| AU2014208242A1 | Australia | A1 | |
| EP1518864B1 | European Patent Office (EPO) | B1 | |
| ES2525762T3 | Spain | T3 | |
| DK1518864T3 | Denmark | T3 | |
| JP5722278B2 | Japan | B2 | |
| JP5722279B2 | Japan | B2 | |
| US2015152189A1 | United States of America | A1 | |
| US2015266972A1 | United States of America | A1 | |
| JP5788432B2 | Japan | B2 | |
| EP2947099A1 | European Patent Office (EPO) | A1 | |
| JP2015211696A | Japan | A | |
| JP2015221827A | Japan | A | |
| JP5837859B2 | Japan | B2 | |
| AU2014208242B2 | Australia | B2 | |
| AU2016204535A1 | Australia | A1 | |
| EP2341078B1 | European Patent Office (EPO) | B1 | |
| AU2016204535B2 | Australia | B2 | |
| DK2341078T3 | Denmark | T3 | |
| JP2017012199A | Japan | A | |
| AU2017200299A1 | Australia | A1 | |
| ES2601241T3 | Spain | T3 | |
| AU2016204535C1 | Australia | C1 | |
| JP6124958B2 | Japan | B2 | |
| US9708409B2 | United States of America | B2 | |
| US9718889B2 | United States of America | B2 | |
| US9718890B2 | United States of America | B2 | |
| AU2017200299B2 | Australia | B2 | |
| JP2017214427A | Japan | A | |
| US2018002442A1 | United States of America | A1 | |
| EP1272527B2 | European Patent Office (EPO) | B2 | |
| US10081683B2 | United States of America | B2 | |
| DK1272527T4 | Denmark | T4 | |
| ES2320412T5 | Spain | T5 | |
| EP1518864B2 | European Patent Office (EPO) | B2 | |
| DK1518864T4 | Denmark | T4 | |
| ES2525762T5 | Spain | T5 |
88 legal events, as 12 offices reported them to INPADOC
Over the term
Point at a mark for the eventEvents
| Event | Code | Office | |
|---|---|---|---|
| Lapsed in a contracting state [announced via postgrant information from national office to epo]LapsedPG25 | PG25 | EP | |
| Lapsed in a contracting state [announced via postgrant information from national office to epo]LapsedPG25 | PG25 | EP | |
| Announcement of lapse in spainLapsedFD2A | FD2A | ES | |
| Ep patent has lapsedLapsedEUG | EUG | SE | |
| Patent expired because of reaching the maximum lifetime of a patentExpiredMK | MK | BE | |
| ExpiryMK07 | MK07 | AT | |
| Patent expired after termination of 20 yearsExpiredPE20 | PE20 | GB | |
| Patent ceasedCeasedPL | PL | CH | |
| Ep patent expiredExpiredEUP | EUP | DK | |
| Patent expired because of reaching the maximum lifetime of a patentExpiredMK | MK | NL | |
| Expiry of rightR071 | R071 | DE | |
| Annual fee paid to national office [announced via postgrant information from national office to epo]GrantedPGFP | PGFP | EP | |
| Publication of translation of european patent specificationUEP | UEP | AT | |
| Annual fee paid to national office [announced via postgrant information from national office to epo]GrantedPGFP | PGFP | EP | |
| Annual fee paid to national office [announced via postgrant information from national office to epo]GrantedPGFP | PGFP | EP | |
| Annual fee paid to national office [announced via postgrant information from national office to epo]GrantedPGFP | PGFP | EP | |
| Annual fee paid to national office [announced via postgrant information from national office to epo]GrantedPGFP | PGFP | EP | |
| Annual fee paid to national office [announced via postgrant information from national office to epo]GrantedPGFP | PGFP | EP | |
| Patent modifiedDC2A | DC2A | ES | |
| Change of representativeR082 | R082 | DE | |
| Annual fee paid to national office [announced via postgrant information from national office to epo]GrantedPGFP | PGFP | EP | |
| Annual fee paid to national office [announced via postgrant information from national office to epo]GrantedPGFP | PGFP | EP | |
| Annual fee paid to national office [announced via postgrant information from national office to epo]GrantedPGFP | PGFP | EP | |
| Annual fee paid to national office [announced via postgrant information from national office to epo]GrantedPGFP | PGFP | EP | |
| Annual fee paid to national office [announced via postgrant information from national office to epo]GrantedPGFP | PGFP | EP | |
| Annual fee paid to national office [announced via postgrant information from national office to epo]GrantedPGFP | PGFP | EP | |
| Translation for ep filed (entry of ep into country)FP | FP | NL | |
| Ep patent has been republished in amended form after opposition at epoOppositionRPEO | RPEO | SE | |
| Amended ep patent with danish claimsT4 | T4 | DK | |
| Patent maintained in amended form27A | 27A | EP | |
| Designated contracting statesAK | AK | EP | |
| Epo decision maintaining patent in amended form now finalR102 | R102 | DE | |
| Maintained in amend formAELC | AELC | CH | |
| Patent maintained in amended formORIGINAL CODE: 0009272PUAH | PUAH | EP | |
| Information on the status of an ep patent application or granted ep patentGrantedSTATUS: PATENT MAINTAINED AS AMENDEDSTAA | STAA | EP | |
| Fee paymentPLFP | PLFP | FR | |
| Fee paymentPLFP | PLFP | FR | |
| Opposition withdrawnWithdrawnORIGINAL CODE: 0009264PLBP | PLBP | EP | |
| Lapsed in a contracting state [announced via postgrant information from national office to epo]LapsedPG25 | PG25 | EP | |
| Fee paymentPLFP | PLFP | FR | |
| Reply of patent proprietor to notice(s) of opposition receivedOppositionORIGINAL CODE: EPIDOSNOBS3PLBB | PLBB | EP | |
| Patent lapsedLapsedMM4A | MM4A | IE | |
| Information modified related to communication of a notice of opposition and request to file observations + time limitOppositionORIGINAL CODE: EPIDOSCOBS2PLAF | PLAF | EP | |
| Lapsed in a contracting state [announced via postgrant information from national office to epo]LapsedPG25 | PG25 | EP | |
| Lapsed in a contracting state [announced via postgrant information from national office to epo]LapsedPG25 | PG25 | EP | |
| Opposition filedOpposition26 | 26 | EP | |
| Opposition filedOpposition26 | 26 | EP | |
| Notice of opposition and request to file observation + time limit sentOppositionORIGINAL CODE: EPIDOSNOBS2PLAX | PLAX | EP | |
| Opposition filedOppositionORIGINAL CODE: 0009260PLBI | PLBI | EP | |
| Opposition filed against patentOppositionR026 | R026 | DE | |
| Lapsed in a contracting state [announced via postgrant information from national office to epo]LapsedPG25 | PG25 | EP | |
| Lapsed in a contracting state [announced via postgrant information from national office to epo]LapsedPG25 | PG25 | EP | |
| Lapsed in a contracting state [announced via postgrant information from national office to epo]LapsedPG25 | PG25 | EP | |
| Lapsed in a contracting state [announced via postgrant information from national office to epo]LapsedPG25 | PG25 | EP | |
| Change of representativeR082 | R082 | DE | |
| Change of representativeR082 | R082 | DE | |
| Translation files for an european patent granted for nl, confirming art. 52 par. 1 or 6 of the patents act 1995GrantedT3 | T3 | NL | |
| Translation of granted ep patentGrantedTRGR | TRGR | SE | |
| Ep patent with danish claimsT3 | T3 | DK | |
| New agentNV | NV | CH | |
| Definitive protectionFG2A | FG2A | ES | |
| Dpma publication of mentioned ep patent grantGrantedR096 | R096 | DE | |
| European patents granted designating irelandGrantedLANGUAGE OF EP DOCUMENT: FRENCHFG4D | FG4D | IE | |
| European patent takes effect as a national patent in ch/liEP | EP | CH | |
| Reference to at number (ep patent enters austrian national phase)REF | REF | AT | |
| Divisional application: reference to earlier applicationAC | AC | EP | |
| Designated contracting statesAK | AK | EP | |
| European patent grantedGrantedNOT ENGLISHFG4D | FG4D | GB | |
| (expected) grantORIGINAL CODE: 0009210GRAA | GRAA | EP | |
| Intention to grant announcedINTG | INTG | EP | |
| Grant fee paidORIGINAL CODE: EPIDOSNIGR3GRAS | GRAS | EP | |
| Despatch of communication of intention to grant a patentORIGINAL CODE: EPIDOSNIGR1GRAP | GRAP | EP | |
| Party data changed (applicant data changed or rights of an application transferred)RAP1 | RAP1 | EP | |
| Designation fees paidAKX | AKX | EP | |
| First examination report despatched17Q | 17Q | EP | |
| Request for examination filed17P | 17P | EP | |
| Designated contracting statesAK | AK | EP | |
| Search report despatchedORIGINAL CODE: 0009013PUAL | PUAL | EP | |
| Party data changed (applicant data changed or rights of an application transferred)RAP1 | RAP1 | EP | |
| Information on inventor provided before grant (corrected)RIN1 | RIN1 | EP | |
| Information on inventor provided before grant (corrected)RIN1 | RIN1 | EP | |
| Information on inventor provided before grant (corrected)RIN1 | RIN1 | EP | |
| Information on inventor provided before grant (corrected)RIN1 | RIN1 | EP | |
| Information on inventor provided before grant (corrected)RIN1 | RIN1 | EP | |
| Information on inventor provided before grant (corrected)RIN1 | RIN1 | EP | |
| Divisional application: reference to earlier applicationAC | AC | EP | |
| Designated contracting statesAK | AK | EP | |
| Public reference made under article 153(3) epc to a published international application that has entered the european phaseORIGINAL CODE: 0009012PUAI | PUAI | EP |
Numbers
- Publication
- 1518864
- Application
- 40288144
Titles3
- German
- Monoklonaler Antikörper gegen Rhesus D
- English
- Antibody against rhesus D
- French
- Anticorps monoclonaux anti-rhesus D
Classification
- CPC, 18
- C07K16/34
- A61K2039/505
- C07K2317/14
- C07K2317/21
- C07K2317/41
- C07K2317/52
- C07K2317/732
- A61P15/00
- A61P17/00
- A61P31/00
- A61P31/04
- A61P31/12
- A61P35/00
- A61P37/02
- A61P37/04
- A61P37/06
- A61P7/00
- A61P7/04
- IPC, 15
- C07K16 34
- C12N15 13
- C12N5 20
- A61K39 395
- G01N33 577
- A61P37 02
- A61P35 00
- A61P31 00
- C12N15 09
- A61P7 00
- A61P15 00
- A61P37 06
- C12N5 10
- C12N15 02
- C12P21 08
Designated states20
- Contracting states, 20
- Austria
- Belgium
- Switzerland
- Cyprus
- Germany
- Denmark
- Spain
- Finland
- France
- United Kingdom
- Greece
- Ireland
- Italy
- Liechtenstein
- Luxembourg
- Monaco
- Netherlands (Kingdom of the)
- Portugal
- Sweden
- Türkiye