Nova Patents
AT419276T

Composition of antibodies with high ADCC

Abstract

The present invention relates to a composition comprising a monoclonal antibody, wherein said antibody has on its glycosylation site (Asn 297) of Fcγ glycan structures of biantennary type, with short chains and low sialylation, characterized in that it comprises a fucose content of between 20% and less than 50%, and its use for the treatment of cancers by immunotherapy for the treatment of infections caused by viral or bacterial pathogens, and for the prevention of Rhesus isoimmunization Rh negative individuals.

Term

No projected expiry on record.

  1. Priority
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89 members in 11 offices

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Priority claims
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0004685FranceA

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FR2807767B1FranceB1
EP1518864A2European Patent Office (EPO)A2
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AT419276TThis recordAustriaT
ATE419276T2AustriaT2
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EP1518864B2European Patent Office (EPO)B2
DK1518864T4DenmarkT4
ES2525762T5SpainT5