EP0979656A3
Composition containing radioisotopes immobilised on solid particles, and its use in brachytherapy
Abstract
Radioactive composition for use in the therapy of neoplastic and non-neoplastic diseases by means of the application of radioactive sources in direct contact with the tumor tissues or within the same, and for use as an aid in radio-guided surgery, containing radioisotopes immobilized on biocompatible or bioabsorbable solid particles. The said solid particles are incorporated in a biocompatible and bioabsorbable matrix consisting of a hypotonic gel containing, in water, from 2 to 30% by weight of polyvinylpyvrrolidone and from 0.01 to 2% by weight of agar-agar or agarose. The invention also concerns a radiopharmaceutical kit or a kit for use in radio-guided surgery comprising, as separate components, the single constituents of the above composition.
Term
Term ended
Projected expiry passed 23 December 2018, 7.8 years ago.
- Priority
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- Projected expiry
- Today
Every citation, both ways
| Document | Relation | Office | Category | Cited during | Relevant claims |
|---|---|---|---|---|---|
| EP0030735A2 | Cites | European Patent Office (EPO) | Y | Search report | 1-15 |
| US5061475A | Cites | United States of America | YD | Search report | 1-15 |
| US5362473A | Cites | United States of America | Y | Search report | 1-15 |
| WO9749335A1 | Cites | World Intellectual Property Organization (WIPO) | YD | Search report | 1-15 |
| MUMPER R J ET AL: "NEUTRON-ACTIVATED HOLMIUM-166-POLY (L-LACTIC ACID) MICROSPHERES: A POTENTIAL AGENT FOR THE INTERNAL RADIATION THERAPY OF HEPATIC TUMORS", JOURNAL OF NUCLEAR MEDICINE, SOCIETY OF NUCLEAR MEDICINE. NEW YORK, US, vol. 32, no. 11, 1 November 1991 (1991-11-01), pages 2139 - 2143, XP000240389, ISSN: 0161-5505 | Non-patent | – | – | Search report | – |
| PATENT ABSTRACTS OF JAPAN vol. 0185, no. 88 (C - 1271) 10 November 1994 (1994-11-10) | Non-patent | – | – | Search report | – |
| MARYANSKI M J ET AL: "RADIATION THERAPY DOSIMETRY USING MAGNETIC RESONANCE IMAGING OF POLYMER GELS", MEDICAL PHYSICS, AMERICAN INSTITUTE OF PHYSICS. NEW YORK, US, vol. 23, no. 5, 1 May 1996 (1996-05-01), pages 699 - 705, XP000592654, ISSN: 0094-2405 | Non-patent | – | – | Search report | – |
| AKUDUGU J M ET AL: "In vitro soft agar model for experimental brachytherapy: Absorbed dose measurements", ENDOCURIETHERAPY/HYPERTHERMIA ONCOLOGY 1996 UNITED STATES, vol. 12, no. 1, 1996, pages 51 - 62, XP008013965, ISSN: 8756-1689 | Non-patent | – | – | Search report | – |
9 members in 4 offices; this record represents the family
Priority claims2
| Document | Office | Kind | Date |
|---|---|---|---|
| RM980303 | Italy | – | |
| RM980303 | Italy | A |
Members9
| Document | Office | Kind | |
|---|---|---|---|
| ITRM980303A0 | Italy | A0 | |
| ITRM980303A1 | Italy | A1 | |
| EP0979656A2 | European Patent Office (EPO) | A2 | |
| IT1299175B1 | Italy | B1 | |
| EP0979656A3This record | European Patent Office (EPO) | A3 | |
| EP0979656B1 | European Patent Office (EPO) | B1 | |
| AT404226T | Austria | T | |
| ATE404226T1 | Austria | T1 | |
| DE69839875D1 | Germany | D1 |
44 legal events, as 5 offices reported them to INPADOC
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| Lapsed in a contracting state [announced via postgrant information from national office to epo]LapsedPG25 | PG25 | EP | |
| Lapsed in a contracting state [announced via postgrant information from national office to epo]LapsedPG25 | PG25 | EP | |
| Lapsed in a contracting state [announced via postgrant information from national office to epo]LapsedPG25 | PG25 | EP | |
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| Lapsed in a contracting state [announced via postgrant information from national office to epo]LapsedPG25 | PG25 | EP | |
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| Lapsed in a contracting state [announced via postgrant information from national office to epo]LapsedPG25 | PG25 | EP | |
| Notification of lapseLapsedST | ST | FR | |
| Lapsed in a contracting state [announced via postgrant information from national office to epo]LapsedPG25 | PG25 | EP | |
| Gb: european patent ceased through non-payment of renewal feeCeasedGBPC | GBPC | EP | |
| Lapsed in a contracting state [announced via postgrant information from national office to epo]LapsedPG25 | PG25 | EP | |
| Patent ceasedCeasedPL | PL | CH | |
| No opposition filedOpposition26N | 26N | EP | |
| No opposition filed within time limitOppositionORIGINAL CODE: 0009261PLBE | PLBE | EP | |
| Information on the status of an ep patent application or granted ep patentGrantedSTATUS: NO OPPOSITION FILED WITHIN TIME LIMITSTAA | STAA | EP | |
| Lapsed in a contracting state [announced via postgrant information from national office to epo]LapsedPG25 | PG25 | EP | |
| Lapsed in a contracting state [announced via postgrant information from national office to epo]LapsedPG25 | PG25 | EP | |
| Lapsed in a contracting state [announced via postgrant information from national office to epo]LapsedPG25 | PG25 | EP | |
| Lapsed in a contracting state [announced via postgrant information from national office to epo]LapsedPG25 | PG25 | EP | |
| Lapsed in a contracting state [announced via postgrant information from national office to epo]LapsedPG25 | PG25 | EP | |
| Lapsed in a contracting state [announced via postgrant information from national office to epo]LapsedPG25 | PG25 | EP | |
| Lapsed in a contracting state [announced via postgrant information from national office to epo]LapsedPG25 | PG25 | EP | |
| Corresponds to:REF | REF | EP | |
| European patents granted designating irelandGrantedFG4D | FG4D | IE | |
| European patent takes effect as a national patent in ch/liEP | EP | CH | |
| Designated contracting statesAK | AK | EP | |
| European patent grantedGrantedFG4D | FG4D | GB | |
| (expected) grantORIGINAL CODE: 0009210GRAA | GRAA | EP | |
| Grant fee paidORIGINAL CODE: EPIDOSNIGR3GRAS | GRAS | EP | |
| Information provided on ipc code assigned before grantRIC1 | RIC1 | EP | |
| Information provided on ipc code assigned before grantRIC1 | RIC1 | EP | |
| Despatch of communication of intention to grant a patentORIGINAL CODE: EPIDOSNIGR1GRAP | GRAP | EP | |
| First examination report despatched17Q | 17Q | EP | |
| Designation fees paidAKX | AKX | EP | |
| Request for examination filed17P | 17P | EP | |
| Designated contracting statesAK | AK | EP | |
| Request for extension of the european patentAX | AX | EP | |
| Search report despatchedORIGINAL CODE: 0009013PUAL | PUAL | EP | |
| Designated contracting statesAK | AK | EP | |
| Request for extension of the european patentAL;LT;LV;MK;RO;SIAX | AX | EP | |
| Public reference made under article 153(3) epc to a published international application that has entered the european phaseORIGINAL CODE: 0009012PUAI | PUAI | EP |
Numbers
- Publication
- 0979656
- Application
- 988307765
Titles3
- German
- Zusammensetzung enthaltend auf festen Teilchen immobilisierte Radioisotopen, sowie deren Verwendung in der Brachytherapie
- English
- Composition containing radioisotopes immobilised on solid particles, and its use in brachytherapy
- French
- Composition contenant des radioisotopes immobilisés sur des particules solides, et son utilisation en brachytherapie
Classification
- CPC, 4
- A61K51/1213
- A61K51/1241
- A61K51/1251
- A61P35/00
- IPC, 1
- A61K51 12
Designated states25
- Contracting states, 19
- Austria
- Belgium
- Switzerland
- Cyprus
- Germany
- Denmark
- Spain
- Finland
- France
- United Kingdom
- Greece
- Ireland
- Italy
- Liechtenstein
- Luxembourg
- Monaco
- Netherlands (Kingdom of the)
- Portugal
- Sweden
- Extension states, 6
- Albania
- Lithuania
- Latvia
- North Macedonia
- Romania
- Slovenia