Bacterial vectors
Abstract
The invention relates to the field of genetic engineering and provides novel DNA molecules which comprise multifunctional origins of replication and/or a DNA sequence coding for the most abundant protein in the supernatant of cultures of Lactococcusspec., named Major Secretion Product (MSP), for its signal peptide and/or the promoter of the MSP gene. The novel DNA molecules are used for the production of novel shuttle vectors for cloning of DNA in at least E. coli and Lactococcusspec. or novel vectors for the expression of homologous or heterologous genes and the production of secreted gene products in gram positive bacteria such as Lactococcusspec. and Bacillus spec.

Term
Term ended
Projected expiry passed 13 March 2011, 15.5 years ago.
- Priority
- Filed
- Published
- Projected expiry
- Today
1 sheet
Sheet 1
Every citation, both waysCites: the store holds 2 of 3
| Document | Relation | Office | Category | Cited during |
|---|---|---|---|---|
| EP0228726A1 | Cites | European Patent Office (EPO) | A | Search report |
| EP0455280A1 | Cites | European Patent Office (EPO) | E | Search report |
| FEMS MICROBIOLOGY LETTERS vol. 30, 1985, ELSEVIER. AMSTERDAM;NL pages 193 - 196; M. J. GASSON ET AL: 'High copy number plasmid vectors for use in lactic streptococci' | Non-patent | – | – | Search report |
| NETHERLANDS MILK AND DAIRY JOURNAL. vol. 40, no. 2/3, 1986, WAGENINGEN NL pages 141 - 154; W. M. DE VOS: 'Gene cloning in lactic streptococci' | Non-patent | – | – | Search report |
| JOURNAL OF BACTERIOLOGY vol. 154, no. 1, 1983, BALTIMORE pages 1 - 9; M. J. GASSON: 'Plasmid complements of Streptococcus lactis NCDO 712 and other lactic Streptococci after protoplast-induced curing' | Non-patent | – | – | Search report |
| GENE. vol. 95, September 1990, AMSTERDAM NL pages 155 - 160; M. VAN ASSELDONK ET AL: 'Cloning of usp45,a gene encoding a secreted protein from Lactococcus lactis subsp. lactis' | Non-patent | – | – | Search report |
32 members in 22 offices
Priority claims4
| Document | Office | Kind | Date |
|---|---|---|---|
| 9006400 | United Kingdom | A | |
| 9006400 | United Kingdom | A | |
| 9006400 | United Kingdom | – | |
| GB19900006400 | – | – | – |
Members32
| Document | Office | Kind | |
|---|---|---|---|
| GB9006400D0 | United Kingdom | D0 | |
| NO911138D0 | Norway | D0 | |
| CA2038706A1 | Canada | A1 | |
| FI911367A | Finland | A | |
| FI911367A7 | Finland | A7 | |
| FI911367L | Finland | L | |
| NO911138L | Norway | L | |
| IE910948A1 | Ireland | A1 | |
| EP0449770A2 | European Patent Office (EPO) | A2 | |
| AU7355891A | Australia | A | |
| HU910958D0 | Hungary | D0 | |
| BR9101137A | Brazil | A | |
| KR910016930A | Republic of Korea | A | |
| HUT57263A | Hungary | A | |
| PT97081A | Portugal | A | |
| ZA912114B | South Africa | B | |
| EP0449770A3This record | European Patent Office (EPO) | A3 | |
| JPH04211384A | Japan | A | |
| NZ237506A | New Zealand | A | |
| TW213488B | Taiwan Province of China | B | |
| AU643511B2 | Australia | B2 | |
| MX25027A | Mexico | A | |
| AR245504A1 | Argentina | A1 | |
| US5559007A | United States of America | A | |
| PT97081B | Portugal | B | |
| EP0449770B1 | European Patent Office (EPO) | B1 | |
| AT174055T | Austria | T | |
| ATE174055T1 | Austria | T1 | |
| DE69130544D1 | Germany | D1 | |
| ES2125864T3 | Spain | T3 | |
| DE69130544T2 | Germany | T2 | |
| DK0449770T3 | Denmark | T3 |
58 legal events, as 6 offices reported them to INPADOC
Over the term
Point at a mark for the eventEvents
| Event | Code | Office | |
|---|---|---|---|
| Lapsed in a contracting state [announced via postgrant information from national office to epo]LapsedPG25 | PG25 | EP | |
| Announcement of lapse in spainLapsedFD2A | FD2A | ES | |
| Notification of lapseLapsedST | ST | FR | |
| Nl: lapsed or anulled due to non-payment of the annual feeLapsedNLV4 | NLV4 | EP | |
| Lapsed in a contracting state [announced via postgrant information from national office to epo]LapsedPG25 | PG25 | EP | |
| Ep patent lapsedLapsedEBP | EBP | DK | |
| Patent ceasedCeasedPL | PL | CH | |
| Gb: european patent ceased through non-payment of renewal feeCeasedGBPC | GBPC | EP | |
| Se: european patent has lapsedLapsedEUG | EUG | EP | |
| Lapsed in a contracting state [announced via postgrant information from national office to epo]LapsedPG25 | PG25 | EP | |
| Lapsed in a contracting state [announced via postgrant information from national office to epo]LapsedPG25 | PG25 | EP | |
| Be: lapsedLapsedBERE | BERE | EP | |
| Lapsed in a contracting state [announced via postgrant information from national office to epo]LapsedPG25 | PG25 | EP | |
| Lapsed in a contracting state [announced via postgrant information from national office to epo]LapsedPG25 | PG25 | EP | |
| Lapsed in a contracting state [announced via postgrant information from national office to epo]LapsedPG25 | PG25 | EP | |
| Lapsed in a contracting state [announced via postgrant information from national office to epo]LapsedPG25 | PG25 | EP | |
| Lapsed in a contracting state [announced via postgrant information from national office to epo]LapsedPG25 | PG25 | EP | |
| Lapsed in a contracting state [announced via postgrant information from national office to epo]LapsedPG25 | PG25 | EP | |
| Lapsed in a contracting state [announced via postgrant information from national office to epo]LapsedPG25 | PG25 | EP | |
| Lapsed in a contracting state [announced via postgrant information from national office to epo]LapsedPG25 | PG25 | EP | |
| European patent in force as of 2002-01-01IF02 | IF02 | GB | |
| Annual fee paid to national office [announced via postgrant information from national office to epo]GrantedPGFP | PGFP | EP | |
| Annual fee paid to national office [announced via postgrant information from national office to epo]GrantedPGFP | PGFP | EP | |
| Annual fee paid to national office [announced via postgrant information from national office to epo]GrantedPGFP | PGFP | EP | |
| Annual fee paid to national office [announced via postgrant information from national office to epo]GrantedPGFP | PGFP | EP | |
| Annual fee paid to national office [announced via postgrant information from national office to epo]GrantedPGFP | PGFP | EP | |
| Annual fee paid to national office [announced via postgrant information from national office to epo]GrantedPGFP | PGFP | EP | |
| Annual fee paid to national office [announced via postgrant information from national office to epo]GrantedPGFP | PGFP | EP | |
| Annual fee paid to national office [announced via postgrant information from national office to epo]GrantedPGFP | PGFP | EP | |
| Annual fee paid to national office [announced via postgrant information from national office to epo]GrantedPGFP | PGFP | EP | |
| Annual fee paid to national office [announced via postgrant information from national office to epo]GrantedPGFP | PGFP | EP | |
| No opposition filedOpposition26N | 26N | EP | |
| No opposition filed within time limitOppositionORIGINAL CODE: 0009261PLBE | PLBE | EP | |
| Information on the status of an ep patent application or granted ep patentGrantedSTATUS: NO OPPOSITION FILED WITHIN TIME LIMITSTAA | STAA | EP | |
| Ep patent with danish claimsT3 | T3 | DK | |
| Definitive protectionFG2A | FG2A | ES | |
| Lapsed in a contracting state [announced via postgrant information from national office to epo]LapsedPG25 | PG25 | EP | |
| It: translation for a ep patent filedITF | ITF | EP | |
| Fr: translation filedET | ET | EP | |
| Corresponds to:REF | REF | EP | |
| European patent takes effect as a national patent in ch/liEP | EP | CH | |
| Designated contracting statesAK | AK | EP | |
| Lapsed in a contracting state [announced via postgrant information from national office to epo]LapsedPG25 | PG25 | EP | |
| Corresponds to:REF | REF | EP | |
| (expected) grantORIGINAL CODE: 0009210GRAA | GRAA | EP | |
| Despatch of communication of intention to grant a patentORIGINAL CODE: EPIDOS IGRAGRAH | GRAH | EP | |
| Despatch of communication of intention to grant a patentORIGINAL CODE: EPIDOS IGRAGRAH | GRAH | EP | |
| Despatch of communication of intention to grantORIGINAL CODE: EPIDOS AGRAGRAG | GRAG | EP | |
| Despatch of communication of intention to grant a patentORIGINAL CODE: EPIDOS IGRAGRAH | GRAH | EP | |
| Despatch of communication of intention to grantORIGINAL CODE: EPIDOS AGRAGRAG | GRAG | EP | |
| Party data changed (applicant data changed or rights of an application transferred)RAP1 | RAP1 | EP | |
| Party data changed (applicant data changed or rights of an application transferred)RAP1 | RAP1 | EP | |
| First examination report despatched17Q | 17Q | EP | |
| Designated contracting statesAK | AK | EP | |
| Search report despatchedORIGINAL CODE: 0009013PUAL | PUAL | EP | |
| Request for examination filed17P | 17P | EP | |
| Designated contracting statesAK | AK | EP | |
| Public reference made under article 153(3) epc to a published international application that has entered the european phaseORIGINAL CODE: 0009012PUAI | PUAI | EP |
Numbers
- Publication
- 0449770
- Publication, DOCDB
- 0449770
- Publication, EPODOC
- EP0449770
- Application
- 810167
- Application, DOCDB
- 91810167
- Application, EPODOC
- EP19910810167
Titles3
- German
- Bakterielle Vektoren
- English
- Bacterial vectors
- French
- Vecteurs bactériens
Classification
- CPC, 6
- C12N15/746
- C12N15/70
- C07K14/315
- C07K14/815
- C12N15/75
- Y10S435/853
- IPC, 15
- C07K14 195
- C07K14 00
- C07K14 315
- C07K14 41
- C07K14 815
- C12N1 21
- C12N15 09
- C12N15 15
- C12N15 31
- C12N15 74
- C12N15 75
- C12P21 02
- C12R1 07
- C12R1 19
- C12R1 225
Designated states1
- Contracting states, 1
- Sweden