Nova Patents
ATE220114T1

Dna sequencing by mass spectrometry via exonuclease degradation

Abstract

Methods for determining the sequence of nucleic acids by cleaving the nueleic acid unilaterally from a first end with an exonuclease activity to sequentially release individual nucleotides, identifying each of the sequentially release nucleotides by mass spectrometry, and determining the sequence of the nueleic acid from the identified nucleotides are disclosed. The method is amenable to multiplexing for simultaneously determining more than one nucleic acid sequence.

Term

Term ended

Projected expiry passed 18 March 2014, 12.5 years ago.

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192 members in 14 offices

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DocumentOfficeKindDate
3473893United States of AmericaA
9402938United States of AmericaW

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