Compositions and methods for immobilizing nucleic acids to solid supports

(57) The manufacturing process of the composite containing at least one bead which carried out the association to the summary solid support medium, and carried out the association to at least one more giant molecule (for example, nucleic acid), and this composite is offered. The obtained surface which was formed from the bead combined with the solid support medium gives advantageously the surface area for fixation of the biological particle or giant molecule (especially nucleic acid) which increased compared with the "flat" surface. Furthermore, the chemical nature of suitable different functional-group-izing from the chemical nature of a solid support medium for fixing the selected giant molecule or biological support medium can be acquired by choosing the bead which has desired functionality.