PL320358A1
Novel derivatives of benzimidazole exhibiting anithistaminic properties
Abstract
New benzimidazole derivatives of formula: <CHEM> in which R1 is H or a short chain hydrocarbon group such as methyl, ethyl, isopropyl, cyclopropyl, vinyl, etc., and R2 is a group selected from among the following: CH2OH, COOH, COOR3 and 4,4-dimethyl-2-oxazolinyl, R3 being a short chain alkyl group such as methyls ethyl, etc., are described. A description is also made of the preparation of these compounds, which have a high H1 antihistaminic and antiallergic activity and are devoid of effects on the central nervous and cardiovascuiar systems.
Term
Term ended
Projected expiry passed 4 June 2017, 9.3 years ago.
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- Filed
- Published
- Projected expiry
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48 members in 27 offices
Priority claims4
| Document | Office | Kind | Date |
|---|---|---|---|
| 9601236 | Spain | A | |
| 9601236 | Spain | A | |
| 9601236 | – | – | – |
| ES19960001236 | – | – | – |
Members48
| Document | Office | Kind | |
|---|---|---|---|
| NO972525D0 | Norway | D0 | |
| HU9700997D0 | Hungary | D0 | |
| CA2206754A1 | Canada | A1 | |
| NO972525L | Norway | L | |
| PL320358A1This record | Poland | A1 | |
| AU2467297A | Australia | A | |
| CZ172397A3 | Czechia | A3 | |
| TR199700464A2 | Türkiye | A2 | |
| TR199700464A3 | Türkiye | A3 | |
| ZA974893B | South Africa | B | |
| EP0818454A1 | European Patent Office (EPO) | A1 | |
| JPH1059961A | Japan | A | |
| CN1176964A | China | A | |
| HRP970307A2 | Croatia | A2 | |
| ES2124167A1 | Spain | A1 | |
| US5877187A | United States of America | A | |
| ES2124167B1 | Spain | B1 | |
| HU9700997A1 | Hungary | A1 | |
| HUP9700997A1 | Hungary | A1 | |
| AR008386A1 | Argentina | A1 | |
| AU725700B2 | Australia | B2 | |
| TW438794B | Taiwan Province of China | B | |
| IN186319B | India | B | |
| CZ289278B6 | Czechia | B6 | |
| HRP970307B1 | Croatia | B1 | |
| RU2182150C2 | Russian Federation | C2 | |
| NO313195B1 | Norway | B1 | |
| CN1105716C | China | C | |
| EP0818454B1 | European Patent Office (EPO) | B1 | |
| AT264317T | Austria | T | |
| ATE264317T1 | Austria | T1 | |
| DE69728608D1 | Germany | D1 | |
| DK0818454T3 | Denmark | T3 | |
| BR9703276A | Brazil | A | |
| PT818454E | Portugal | E | |
| SI0818454T1 | Slovenia | T1 | |
| DE69728608T2 | Germany | T2 | |
| PL188908B1 | Poland | B1 | |
| MXPA97004127A | Mexico | A | |
| CA2206754C | Canada | C | |
| JP4218991B2 | Japan | B2 | |
| LU91798I2 | Luxembourg | I2 | |
| NO2011008I1 | Norway | I1 | |
| DE122011000006I1 | Germany | I1 | |
| FR11C0023I1 | France | I1 | |
| HU227598B1 | Hungary | B1 | |
| FR11C0023I2 | France | I2 | |
| NO2011008I2 | Norway | I2 |
Numbers
- Publication, DOCDB
- 320358
- Publication, EPODOC
- PL320358
- Application
- 97320358
- Application, DOCDB
- 32035897
- Application, EPODOC
- PL19970320358
Titles
- English
- NOVEL DERIVATIVES OF BENZIMIDAZOLE EXHIBITING ANITHISTAMINIC PROPERTIES
Classification
- CPC, 4
- C07D401/04
- A61P11/06
- A61P37/08
- A61P43/00
- IPC, 12
- A61K31 4184
- A61K31 4427
- C07D403 04
- A61K31 445
- A61P37 08
- A61P43 00
- C07D235 04
- C07D235 06
- C07D401 04
- C07D413 14
- H02B11 04
- H02B11 24