Nova Patents
NO993121L

Stable liquid interferon formulations

Abstract

Liquid interferon compositions having a pH between 4.0 and 7.2 are described. The compositions comprise interferon-beta and a stabilizing agent at between about 0.3 % and 5 % by weight which is an amino acid selected from the group consisting of acidic amino acids, arginine and glycine. If needed, salt is added to provide sufficient ionic strength. The liquid composition has not been previously lyophilized or previously cavitated. The liquid is preferably contained within a vessel having at least one surface in contact with the liquid that is coated with a material inert to adsorption of interferon-beta. A kit for parenteral administration of a liquid interferon formulation and a method for stabilizing liquid interferon compositions are also described.

Term

No projected expiry on record.

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80 members in 29 offices

This recordMember, by publication datePriority claim19 more offices are in the list below

Priority claims8

Priority claims
DocumentOfficeKindDate
3435396United States of AmericaP
3435396United States of AmericaP
9723817United States of AmericaW
9723817United States of AmericaW
3435396–––
9723817–––
US19960034353P–––
WO1997US23817–––

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CA2275890A1CanadaA1
WO9828007A1World Intellectual Property Organization (WIPO)A1
AU5619198AAustraliaA
IS5087AIcelandA
NO993121D0NorwayD0
NO993121LThis recordNorwayL
EP0948358A1European Patent Office (EPO)A1
CZ228299A3CzechiaA3
TR199901968T2TürkiyeT2
SK85899A3SlovakiaA3
CN1245434AChinaA
EA199900597A1Eurasian Patent Organization (EAPO)A1
PL334365A1PolandA1
EE9900313AEstoniaA
BG103594ABulgariaA
BR9714434ABrazilA
IL130524D0IsraelD0
HU0000829A2HungaryA2
HUP0000829A2HungaryA2
HK1025040A1Hong Kong, ChinaA1
KR20000069664ARepublic of KoreaA
AU738362B2AustraliaB2
NZ336548ANew ZealandA
JP2001519770AJapanA
HU0000829A3HungaryA3
HUP0000829A3HungaryA3
EA002754B1Eurasian Patent Organization (EAPO)B1
NZ512792ANew ZealandA
EE200300127AEstoniaA
US2003190307A1United States of AmericaA1
EE04223B1EstoniaB1
EE04266B1EstoniaB1
EP0948358B1European Patent Office (EPO)B1
AT270899TAustriaT
ATE270899T1AustriaT1
DE69729880D1GermanyD1
PT948358EPortugalE
DK0948358T3DenmarkT3
ES2224290T3SpainT3
SI0948358T1SloveniaT1
HU224222B1HungaryB1
DE69729880T2GermanyT2
IL130524AIsraelA
CN1222315CChinaC
IS2070BIcelandB
CN1733296AChinaA
SK284989B6SlovakiaB6
HK1092048A1Hong Kong, ChinaA1
PL193447B1PolandB1
KR20070052363ARepublic of KoreaA
BG109523ABulgariaA
BG65171B1BulgariaB1
JP2007204501AJapanA
US2008044381A1United States of AmericaA1
US2008050338A1United States of AmericaA1
US2008050339A1United States of AmericaA1
BG65418B1BulgariaB1
CZ300636B6CzechiaB6
NO327844B1NorwayB1
CN1733296BChinaB
US2010239531A1United States of AmericaA1
JP2011068694AJapanA
KR101042660B1Republic of KoreaB1
CA2275890CCanadaC
EP0948358B2European Patent Office (EPO)B2
JP2012006979AJapanA
JP4878664B2JapanB2
ES2224290T5SpainT5
DK0948358T4DenmarkT4
SI0948358T2SloveniaT2
DE69729880T3GermanyT3
US8512691B2United States of AmericaB2
US8512692B2United States of AmericaB2
US2013302281A1United States of AmericaA1
JP2014098029AJapanA
US8932574B2United States of AmericaB2
US2015093359A1United States of AmericaA1
JP5851695B2JapanB2
MX337876BMexicoB
US9522174B2United States of AmericaB2