Ganglioside-associated recombinant antibodies and the use thereof in the diagnosis and treatment of tumours
Abstract
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Term
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1 claim: 1 independent, 0 dependent
- 1(72) Oppfinner forts. Mauro A Alfonso Fernandez, Ciudad de la Habana 10600, CU Ana Maria Vazquez Lopez, Ciudad de la Habana 10500, CU Rolando Perez Rodriguez, Ciudad de la Habana 10500, CU Alexis Pérez Gonzalez, Ciudad de la Habana 13100, CU Adriana Carr Pérez, Ciudad de la Habana 10500, CU Yildian Diaz Rodriguez, Ciudad de la Habana 10300, CU
1 paragraph, as filed
The present invention relates to immunology and, more specifically, immunotherapeutic combinations used to control the growth and / or cell proliferation of tumors. In accordance with the present invention, a therapeutic effect against tumors is observed by combining idiotypic vaccines whose active ingredient is an antiganglioside antibody (Abl), with idiotypic vaccines whose active ingredient is anti-idiotypic antibody (Ab2) obtained against an antiganglioside antibody, or vaccines whose active ingredient is one or more gangliosides. Combinations of these vaccines which cause a synergistic therapeutic effect against tumors are described. The above-mentioned combinations can be used for patients in various clinical states of tumors expressing gangliosides.
134 members in 38 offices
Priority claims8
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| 20010084 | Cuba | A | |
| 20010084 | Cuba | A | |
| 0200002 | Cuba | W | |
| 0200002 | Cuba | W | |
| 00084 | – | – | – |
| 0200002 | – | – | – |
| CU20010000084 | – | – | – |
| WO2002CU00002 | – | – | – |
Members134
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| EA200301097A1 | Eurasian Patent Organization (EAPO) | A1 | |
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| KR20080080680A | Republic of Korea | A | |
| AT406386T | Austria | T | |
| ATE406386T1 | Austria | T1 | |
| DE60223547T2 | Germany | T2 | |
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| PT1384726E | Portugal | E | |
| DK1384726T3 | Denmark | T3 | |
| MY137078A | Malaysia | A | |
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1 legal event, as the office reported them to INPADOC
Events
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| Lapsed by not paying the annual feesLapsedMM1K | MM1K |
Numbers
- Publication, DOCDB
- 20034436
- Publication, EPODOC
- NO20034436L
- Application
- 4436
- Application, DOCDB
- 20034436
- Application, EPODOC
- NO20030004436
Titles2
- Norwegian
- Immunoterapeutiske kombinasjoner for behandling av tumorer som over-uttrykker gangliosider
- English
- Immunotherapeutic combinations for the treatment of tumors overexpressing gangliosides
Classification
- CPC, 31
- A61K31/7032
- C07K16/18
- C07K16/4208
- A61K31/739
- A61K39/395
- A61K39/39558
- A61K2039/505
- A61K2039/55505
- C07K16/00
- C07K16/30
- C07K16/3076
- C07K16/3084
- C07K16/4241
- C07K16/4266
- C07K2317/24
- C07K2317/565
- C07K2317/567
- A61K39/39566
- A61P35/00
- A61P35/04
- A61P37/00
- A61P37/04
- A61P43/00
- A61K39/001171
- C07K2317/76
- C12N5/0694
- C12N5/163
- G01N33/57415
- G01N33/577
- G01N33/686
- G01N2800/7028
- IPC, 21
- C12N15 09
- A61K31 7032
- A61K31 739
- A61K39 00
- A61K39 395
- A61P35 00
- A61P35 04
- A61P37 00
- A61P37 04
- A61P43 00
- C07K16 00
- C07K16 18
- C07K16 30
- C07K16 42
- C07K16 46
- C12N1 15
- C12N1 19
- C12N1 21
- C12N5 10
- C12N5 20
- C12P21 08