Orally administered controlled drug delivery system providing temporal and spatial control

A pharmaceutical composition in the form of tablets or capsules that provides a combination of temporal and spatial control of the controlled administration of the drug to a patient, for effective therapeutic results. The pharmaceutical composition it comprises a drug, a gas generating component, a foaming agent, a viscosity imparting agent and, optionally, a gel-forming polymer. The fluffing agent belongs to a class of compounds known as superdisintegrants (for example, cross-linked polyvinylpyrrolidone or sodium carboxymethylcellulose). Initially the delivery agent of viscosity and, after this, the gel-forming polymer forms a hydrated gel matrix that traps the gas, causing The hydrated gel matrix of the tablet creates a sinuous diffusion path of the drug, resulting in the release prolonged drug (temporary control). The preferred formulations of ciprofloxacin once a day comprises 69.9% of Ciprofloxacin base, 0.34% Sodium alginate, 1.03% Xanthan gum, 13.7% sodium bicarbonate, 12.1% cross-linked polyvinylpyrrolidone and, optionally, other pharmaceutical excipients, the formulations are in the form of a tablet coated or uncoated or a capsule.