Delivery particle.
Abstract
The present application relates to benefit agent delivery compositions comprising a material selected from the group consisting of agglomerates comprising chelant and an encapsulated benefit agent; agglomerates comprising an encapsulated benefit agent having a shell comprising chelant; agglomerates comprising an encapsulated benefit agent having a core comprising chelant and combinations thereof, and processes for making and using such benefit agent delivery compositions.
Term
4.1 yearsleft in the term
Expires 4 November 2030.
- Priority
- Filed
- Granted
- Today
- Expires
15 claims: 2 independent, 13 dependent
- 1NOVEDAD DE LA INVENCIÓN NOVELTY OF THE INVENTION CLAIMS REIVINDICACIONES 1. - Un encapsulado, caracterizado porque comprende un núcleo, una cubierta que tiene una superficie interna y externa, y un recubrimiento, dicha cubierta encapsula dicho núcleo, dicho recubrimiento recubre la superficie externa de dicha cubierta, dicho recubrimiento comprende un polímero catiónico que comprende hidroxiletilcelulosa y un polímero aniónico que comprende carboxilmetllcelulosa, en donde la relación del polímero catiónico al polímero aniónico es de aproximadamente 5:1 a aproximadamente 1:5 en peso, y en donde el encapsulado comprende, con base en el peso total del encapsulado, de aproximadamente 1% a aproximadamente 25% del recubrimiento. one. - An encapsulate, characterized in that it comprises a core, a covering having an internal and external surface, and a covering, said covering encapsulates said core, said covering covers the external surface of said covering, said covering comprises a cationic polymer comprising hydroxy ethyl cellulose and an anionic polymer comprising carboxymethyl cellulose, wherein the ratio of the cationic polymer to the anionic polymer is from about 5: 1 to about 1: 5 by weight, and wherein the package comprises, based on the total weight of the package, from about 1% to about 25% of the coating. .
- 1414, - A method for cleaning or treating a surface or fabric, characterized in that it optionally comprises washing and / or rinsing said 14,- Un método para limpiar o tratar una superficie o tela, caracterizado porque comprende, opcionalmente, lavar y/o enjuagar dicha
Independent claims2
840 paragraphs in 267 sections, as filed
(54) Title: SUPPLY PARTICLE. (54) Title: DELIVERY PARTIOLE.
(57) Summary
The present application relates to beneficial agent delivery compositions comprising a material selected from the group consisting of agglomerates comprising chelator and an encapsulated beneficial agent ; agglomerates comprising an encapsulated beneficial agent having a covering comprising chelator; agglomerates comprising an encapsulated beneficial agent having a core comprising a chelator and combinations thereof, as well as processes for manufacturing and using these beneficial agent delivery compositions.
(57) Abstract
The present application relates to benefit agent delivery compositions comprising a material selected from the group consisting of agglomerates comprising chelant and an encapsulated benefit agent; agglomerates comprising an encapsulated benefit agent having a Shell comprising chelant; agglomerates comprising an encapsulated benefit agent having a core comprising chelant and combinations thereof, and processes for making and using such benefit agent delivery compositions.
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Institute
Mexican Property
Industrial i
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PATENT TITLE NO. 337136
Headlines):
Home:
THE PROCTER & GAMBLE COMPANY One Procter & Gamble Plaza, Cincinnati, OhioJ 45202, USA Name: SUPPLY PARTICLE.
Classification: lnt.CI.8: A61K8 / 11; B01J13 / 02; C11D17 / 00; C11D3 / 50
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In accordance with the counted from the faith rights.
Who subscribes the preserjfe title Icj & iace based on the provisions ~ industrial PoT.
irrogables, people the
Law of __ __________ f / 05/1999,
01/05/2006, 06/05/2009 / 06.06 / OT / 2010, 18/8572010728706/2010, ^ 7701/20127 04/09/2012); 1st articles. 3 ”fraction V Clause a). 4th and 12th fractions I and III of the Regulation of the Mexican Institute of Industrial Property (DOF 14/12/1999, amended on 07/01/2002, 07/15/2004, 07/28/2004 and 07/09/2004 / 2007); Articles 1, 3, 4, 5, section V, subsection a), 16 sections I and III and 30 of the Organic Statute of the Mexican Institute of Industrial Property (DOF) 12/27/1999, amended on 10/10/2002, 07/29/2004, 08/04/2004 and 09/13/2007); 1, 3 and 5 Clause a) of the Agreement that delegates powers to the Deputy Directors General. Coordinator. Divisional Directors, Holders of the Regional Offices, Divisional Deputy Directors, Departmental Coordinators and other subordinates of the Mexican Institute of Industrial Property. (DOF 12/15/1999, amended on 02/04/2000, 07/29/2004, 08/04/2004 and 09/13/2007).
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Sand! No. 550. Floor i,
Col. Pueblo Santa María Tepepan. XochímHco, CP 16023,
Mexico City
Tel. (55) 53 34 07 OOwww impi oob.mx
Issue Date: February 12, 2016
THE DIVISIONAL DIRECTOR OF PATENTS
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NAHANNY CANAL REYES
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MX / 2016/13053
SUPPLY PARTICLE
INS ^ r
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FIELD OF THE INVENTION
The present application relates to agglomerates / particles comprising encapsulated beneficial agent compositions, to compositions comprising the agglomerates / particles, as well as to processes for manufacturing and using such agglomerates / particles and compositions comprising those agglomerates / particles.
BACKGROUND OF THE INVENTION
Beneficial agents such as perfumes, silicones, waxes, flavors, vitamins, and fabric softening agents are expensive and generally less effective when used in large numbers in personal care compositions, cleaning compositions, and fabric care compositions. . Accordingly, there is a need to optimize the efficacy of the beneficial agents. One method of achieving this goal is to improve the delivery efficiency of such beneficial agents.
Unfortunately, it is difficult to improve the delivery efficiency of beneficial agents, since the agents may be lost due to the physical or chemical characteristics of the agents, or the agents may be incompatible with other components of the composition or with the treated site.
IMPI
INS
In an effort to improve the delivery efficiency of beneficial agents, the industry, in many cases, encapsulates these beneficial agents. Unfortunately, in some cases, beneficial agents, for example, raw materials and perfume flavorings can degrade over time. This results in decreased efficiency and / or the need for additional amounts of those materials to compensate for the loss.
Accordingly, there is a need for a process and benefit delivery agent that minimizes or eliminates one or more problems associated with the use of encapsulates.
BRIEF DESCRIPTION OF THE INVENTION
The present application relates to beneficial agent delivery compositions comprising a material selected from the group consisting of: an agglomerate, a particulate and / or extruded product comprising chelator and an encapsulated beneficial agent having a core and an encapsulating shell that core; an agglomerate, a particulate, and / or an extruded product comprising a chelator and an encapsulated beneficial agent having a core and a shell encapsulating that core; the encapsulated beneficial agent comprises chelator in the shell and / or core;
an agglomerate, a particulate and / or an extruded product comprising an encapsulated beneficial agent having a core and a shell which
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encapsulates that core; This encapsulated beneficial agent comprises a chelator in its shell and / or core and combinations thereof, as well as processes for manufacturing and using the beneficial agent delivery compositions.
DETAILED DESCRIPTION OF THE INVENTION
Definitions
As used in this description, "consumer product" means products or devices for baby care, beauty care, fabric and home care, family care, feminine care, health care, snacks and / or beverages or products intended to be used or consumed in the form in which they are sold and not intended for subsequent commercial manufacture or modification. Such products include, but are not limited to, diapers, bibs, cloths; products for and / or methods related to the treatment of hair (of humans, dogs and / or cats), including bleaching, coloring, dyeing, conditioning, shampooing, styling; deodorants and antiperspirants; personal cleanliness; cosmetics; skin care including the application of creams, lotions and other products that are applied topically for use by a consumer; and shaving products, products for and / or methods related to the treatment of fabrics, hard surfaces and any other surface in the field of fabric and home care, including care of the
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air, car care, dishwashing, fabric conditioning, (including softening), laundry detergent, additive and / or care for washing and rinsing, cleaning and treating hard surfaces, and other cleaning products for consumer use Institutional; products and / or methods relating to toilet paper, disposable tissues, paper napkins and / or paper towels; tampons, feminine cloths; oral care products and / or methods, including toothpastes, tooth gels, dental rinses, denture adhesives, teeth whitener; Over-the-counter health care products, including cough and cold remedies, pain relief products, prescription pharmaceuticals, animal health and nutrition, and water purification; Processed food products intended initially for consumption between traditional meals or as an accompaniment to meals (non-limiting examples include potato chips, fried tortillas, popcorn, pretzels, corn sticks, cereal bars, vegetable sticks or crisps, snack mixes , party mixes, miscellaneous grain sticks, crackers, cheese sandwiches, greaves, corn sandwiches, ball sandwiches, extruded sandwiches and breadsticks); and coffee.
As used herein, the term "cleaning composition" includes, unless otherwise indicated, "high performance" laundry agents, granular or in powder form for various uses, especially detergents cleaning; liquids, washing agents in gel or paste form for various uses,
I '· /// LA especially the so-called high-performance' liquid type; liquid detergents for delicate fabrics; dishwashing agents for dishes or low-performance dishwashing agents, especially those of the high foam type; dishwashing agents, including various tablets, granules, liquids, and auxiliary rinse types for household or institutional use; liquid cleaning agents and disinfectants, including antibacterial types for manual washing, cleaning bars, mouth rinses, denture cleansers, toothpastes, car or carpet shampoos, bathroom cleaners; shampoos and rinses for hair; shower gels and bath foams and metal cleaners; as well as cleaning aids such as bleaching additives and "stick stain removers" or pretreatment types, products with substrates such as blotting sheets, dry and wet wipes and pads, non-woven substrates and sponges; as well as sprinklers and vaporizers.
As used herein, the term "chelating agent" means an agent capable of complexing with a metal ion.
As used in the present description, the term "polidentate type chelator" means a chelator capable of complexing with a metallic ion at two or more points.
As used herein, the term “fabric care composition” includes, unless otherwise indicated, fabric softening compositions, compositions for • irewwWMSL'rtSi '' ''> '·: κΐί<sup>Λ</sup>'“7 · ••«' a * ®<sup>-</sup>®'<sup>1</sup> improve fabrics, compositions to refresh fabrics and combinations of these.
As used herein, the terms "encapsulated beneficial agent" and "delivery particle-containing beneficial agent" are synonyms, and the terms "capsule" and "microcapsule" are also synonyms.
As used herein, articles including "a" and "ones", when used in a claim, mean one or more of what is claimed or described.
As used herein, the terms "include", "include" and "including (n)" are not limiting.
The test methods described in the test method section of the present application should be used to determine the respective parameter values of applicants' inventions.
Unless otherwise indicated, all levels of the component or composition refer to an active portion of that component or composition and exclude impurities, for example residual solvents or by-products, which may be present in commercially available sources of such components or compositions.
All percentages and proportions are calculated by weight, unless otherwise indicated. All percentages and proportions are calculated based on the total composition, unless otherwise indicated.
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It should be understood that any maximum * numerical limit given in. this description includes any lower numerical limits, as if the lower numerical limits had been explicitly noted in this description. All minimum numerical limits cited in this specification will include all major numerical limits as if such major numerical limits had been explicitly cited in the present description. All numerical ranges cited in this description will include all minor ranges that fall within the major numerical ranges as if all minor numerical ranges had been explicitly cited in the present disclosure.
Agglomerated Beneficial Agent / Particle / Extruded Product Delivery Composition
Applicants have recognized that particular materials used as beneficial agents — particularly materials comprising aldehyde entities, eg, certain perfumes and aromas — degrade at unexpectedly high rates when encapsulated. Without being bound by theory, applicants believe that degradation of the material may be the result of oxidation of oxygen in the presence of catalytic materials. For example, applicants believe that degradation of perfume raw material may be the result of oxygen oxidation in the presence of metal catalysts, such as Fe. Specifically, applicants believe that Fe2Ü3 — which may be a common impurity in the silica used to prepare encapsulates such as those described herein — may result in catalysis of Fe from oxidation of the aldehyde to carboxylic acid by oxygen, leading to results in the degradation of the aldehyde-containing encapsulated materials. Applicants have recognized that such degradation can be significantly reduced by adding a chelator.
In one aspect, beneficial agent delivery compositions are described comprising a material selected from the group consisting of: a chipboard, a particulate and / or extruded product comprising chelator and an encapsulated beneficial agent having a core and encapsulating shell that core; an agglomerate, a particulate, and / or an extruded product comprising a chelator and an encapsulated beneficial agent having a core and a shell encapsulating that core; the encapsulated beneficial agent comprises chelator in the shell and / or core;
an agglomerate, a particulate and / or an extruded product comprising an encapsulated beneficial agent having a core and a shell encapsulating that core; This encapsulated beneficial agent comprises a chelator in the shell and / or core and combinations thereof.
In one aspect, a beneficial agent delivery composition is described which may be an agglomerate, a particulate and / or an extruded product which may comprise, based on the total weight of the beneficial agent supply;
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a.) from about 2% to about 97%, from about 10% to about 90%, from about 15% to about 85%, from about 20% to about%, from about 25% to about 75%, or even from about 30% to about 70% of an encapsulated beneficial agent; the encapsulated beneficial agent comprises a core and a shell that encapsulates the beneficial agent; the encapsulated beneficial agent comprises a sufficient amount of beneficial agent to provide, based on the total weight of the benefit delivery composition, from about 1% to about 85%, from about 8% to about 80%, from about 12% to about 75%, from about 15% to about 65%, from about 20% to about 60%, or even from about 25% to about 55% of beneficial agent;
b.) a chelating agent; the chelating agent is present in the beneficial agent delivery composition, and / or in the shell and / or in the core of the encapsulated beneficial agent;
c.) from about 1% to about 50%, from about 2% to about 45%, from about 3% to about 40%, from about 4% to about 37%, from about 5% to about 35%, or even from about 6% to about 30% of a plasticizer;
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Ifei · Z 't _ - d: l; i_ ~' -d. ) from about 1% to about 5%, 9e about 2% to about 45%, from about 3% to about 35%, from about 4% to about 30%, from about 5% to about 25%, or even from about 6% to about 20% of a binder; and
and. ) optionally, from about 1% to about 50%, from about 2% to about 45%, from about 5% to about 40%, from about 7% to about 35%, from about 9% to about 30%, or even from about 10% to about 27% of a dusting agent.
In one aspect of the aforementioned beneficial agent delivery composition, the encapsulated beneficial agent could comprise a perfume microcapsule, a binder, and mixtures thereof. In one aspect, the perfume microcapsule may comprise a shell, the shell comprises crosslinked melamine formaldehyde.
In one aspect of the aforementioned beneficial agent delivery composition,
to. ) the encapsulated beneficial agent may comprise a perfume microcapsule, the perfume microcapsule comprises a core and a shell that encapsulates the core, the shell and / or the core comprise crosslinked melamine formaldehyde and a ch elating agent;
b. ) the plasticizer can comprise water;
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c. ) the binder can be selected from the group that * ~ T_ | ii _ i un _ consists of celluloses, including methyl cellulose, including CMC, and their derivatives; alginate and its derivatives; starches; polyvinyl alcohols, polyethylene oxide; polyvinylpyrrolidone; polysaccharides, including chitosan and / or natural gums, including carrageenan; polyacrylates, including crosslinked polyacrylates; waxes; polyethylene glycols, for example, polyethylene glycols having a molecular weight (weighted average) greater than 4000 Da or even from about 4000 Da to about 15,000 Da; ethoxylate alcohols; surfactants and mixtures thereof; and
d. ) this dusting agent can be selected from the group consisting of silica; zeolites; amorphous aluminosilicates; clays; starches; cellulose; water soluble salts, including sodium chloride, sodium sulfate, magnesium sulfate and / or sodium carbonate; polysaccharides including sugars and mixtures thereof.
In one aspect, any of the beneficial agent delivery compositions described in the present specification may comprise an encapsulated beneficial agent which, in turn, may comprise a beneficial agent selected from the group consisting of perfumes; polishes; insect repellent; silicones; waxes; flavorings; vitamins; fabric softening agents; skin care agents, including paraffins; enzymes; antibacterial agents; bleach and mixtures thereof. In one aspect, the encapsulated beneficial agent is a perfume comprising an aldehyde.
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In one aspect, any of the beneficial agent delivery compositions described in the present specification may comprise a chelator selected from the group consisting of chelants comprising a polyldentate which, in turn, comprises a soft base, chelators comprising a polydentate which it does not comprise a smooth base and combinations thereof.
In one aspect, any of the beneficial agent delivery compositions described in the present specification may comprise a chelator comprising a polidentate comprising a soft base, as determined by the Lewis definition of atoms with a pair of solitary electrons in the highest occupied molecular orbital. In this regard, the chelator comprising a polidentate comprising a smooth base may be present in an amount of from about 0.0001% to about 10% or from about 0.01% to about 0.1%, based on the total weight of the agglomerate. In one aspect, the polyidentate comprising a soft base may comprise a material selected from the group consisting of polyamines (eg, diethylenetriamine, triethylenetriamine, polyethyleneimines); amino alcohols (p. eg, triethanolamine, Nhydroxyethylethylene diamine, aminoethylethanolamine (AEEA); aminocarboxylic acids, (p. Eg, ethylenediaminetetracetic acid (EDTA), diethylene triamine penta (methylenophosphonic acid) (DTPMP), diethylene triamine pentaacetic acid (DTPA), ethylenediamine diethylacetyl-ethynediamine-ethyldiamine diuretic amino acid (NDS) HEIDA), dihydroxyethylglycine (DHEG), ethylenediaminetetrapropionic acid (EDTP)) and combinations thereof. In one aspect, the polidentate comprising a smooth base may comprise ethylenediamine disuccinic acid.
In one aspect, any of the beneficial agent delivery compositions described in the present specification may comprise a chelator comprising a polidentate which does not comprise a soft base, wherein the chelator comprising the polidentate which does not comprise a soft base may be present in an amount of from about 0.01% to about 50% or from about 0.1% to about 5%, based on the total weight of the chipboard. In one aspect, the polidentate type chelator that does not comprise a soft base may comprise a material selected from the group consisting of acrylic polymers, hydroxycarboxylic acids (eg, tartaric acid, citric acid, malic acid, gluconic acid, ferulic acid, acid lactic, glucuronic acid); 1,3-diketones (eg, ascorbic acid), polyphosphates (eg. eg, citric acid, dicarboxymethylglutamic acid, malic acid, nitrilotriacetic acid, oxalic acid, phosphoric acid, succinic acid) and combinations thereof.
In one aspect, the chelators that are useful in the beneficial agent delivery compositions described in the present specification may comprise a peptide and / or a polar amino acid. The irW'l polar amino acid may include arginine, asparagine, aspartic acid, iiii. '. Ii.'auu ^ ü.mutaws glutamic, glutamine, lysine and combinations thereof.
In one aspect, any of the beneficial agent delivery compositions described in the present specification may comprise a chelator that is acceptable for use in products that are edible to humans and / or other animals. These chelators include polyphosphates (eg, sodium tripolyphosphate, hexametaphosphoric acid, sodium acid pyrophosphate, sodium pyrophosphate, tetrasodium pyrophosphate, sodium hexametaphosphate, sodium metaphosphate); aminocarboxylic acids (e.g. eg, ethylenediaminetetraacetic acid (EDTA), 1,2-bis (2-ainino-phenoxy) ethaneΝ, Ν, Ν'Ν'-tetraacetic acid (EGTA), ethylenebis (oxyethylenenitrile) -tetraacetic acid (BAPTA), N acid - (hydroxyethyl) -ethylenediaminotriacetic (HEDTA), diethylene-triaininpentaacetic acid (DTPA), N-dihydroxyethylglycine (2-HxG), ethylenebis (hydroxyphenylglycine) (EHPG), glutamic acid, aspartic acid, glycine, lysine; 1,3-diketones (eg, ascorbic acid); hydroxycarboxylic acids (eg. eg, tartaric acid, citric acid, malic acid, gluconic acid, ferulic acid, lactic acid, glucuronic acid); polyamines (eg, diethylenetriamine, triethylenetriamine); amino alcohols (eg triethanolamine, N-hydroxyethylethylenediamine, aminoethylethanolamine (AEEA); polymers (eg polyethyleneimine s, polymethacryloketone, poly (p-vinylbenzyliminodiacetic acid)), phosphonic and bisphosphonic acids (e.g. eg, nitrilotrimethylene phosphonic acid, ethylenediaminetetra-diethylene phosphonic acid), hydroxyethylidene diphosphonic acid) and mixtures thereof.
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In one aspect of the aforementioned beneficial agent delivery composition, the plasticizer may comprise a material selected from the group consisting of water; alcohols including glyceri, ethanol, and / or propane-1-diol; glycols, including polyethylene glycols, e.g. eg, polyethylene glycols having a molecular weight (weighted average) d less than 600 Da or even from about 600 Da to about 200 Da; fatty acids; petroleum derivatives, including paraffins, petrolatum, and / or mineral oils; vegetable oils, and mixtures thereof; In one aspect, the plasticizer may comprise a material selected from the group consisting of water and alcohols, and mixtures thereof; In one aspect, the plasticizer may comprise a material selected from the group consisting of water and glyceri and mixtures thereof; in one aspect, the plasticizer may comprise water.
In one aspect of the aforemention ed beneficial agent delivery composition, the binder may comprise a material selected from the group consisting of celluloses, including methyl cellulose, including CMC, and derivatives thereof; alginate and its derivatives; starches; polyvinyl alcohols; polyethylene oxide; polyvinylpyrrolidone; polysaccharides, including chitosan and / or natural gums, including carrageenan; polyacrylates, including crosslinked polyacrylates; waxes; polyethylene glycols, eg eg, polyethylene glycols having a molecular weight (weighted average) greater than 4000 Da or even from about 4000 Da to about 15,000 Da, ethoxylate alcohols; surfactants and
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INDI'ST. '.AL -mixtures thereof; in one aspect, the binder may comprise a<sub>n</sub>Jtanxan. '' Rj * ALiiii << ι ·> ι material selected from the group consisting of cellulose, including methylcellulose, including CMC, and its derivatives; alginate and its derivatives; starches; polyvinyl alcohols; polysaccharides, including chitosan and / or natural gums, including carrageenan; polyacrylates, including crosslinked polyacrylates; polyethylene glycols, e.g. eg, polyethylene glycols having a molecular weight (weighted average) greater than 4000 Da or even from about 4000 Da to about 15,000 Da, and mixtures thereof; In one aspect, the binder may comprise a material selected from the group consisting of celluloses, including methyl cellulose, including CMC, and derivatives thereof; alginate and its derivatives; starches; polyvinyl alcohols; polyacrylates, including crosslinked polyacrylates; polyethylene glycols, e.g. eg, polyethylene glycols having a molecular weight (weighted average) greater than 4000 Da or even approximately
4000 Gives approximately 15,000 Da, and mixtures thereof; In one aspect, the binder can comprise a material selected from the group consisting of celluloses, including methylcellulose, including CMC; polyacrylates, including crosslinked polyacrylates; polyethylene glycols, e.g. Eg polyethylene glycols having a molecular weight (weighted average) greater than 4000 Da or even from about 4000 Da to about 15,000 Da, and mixtures thereof.
In one aspect of the aforementioned beneficial agent delivery composition, the dusting agent may comprise a
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material selected from the group consisting of silicas; zeolites; amorphous aluminosilicates; clays; starches; cellulose; water soluble salts, including sodium chloride, sodium sulfate, magnesium sulfate and / or sodium carbonate; polysaccharides, including sugars, and mixtures thereof; in one aspect, the dusting agent may comprise a material selected from the group consisting of silicas; aluminosilicates, including zeolite; clays; starches; cellulose; polysaccharides, including sugars, and mixtures thereof; in one aspect, the dusting agent may comprise a material selected from the group consisting of silicas; aluminosilicates, including zeolite; clays; starches; celluloses, and mixtures thereof; in one aspect, the dusting agent may comprise a material selected from the group consisting of silicas; aluminosilicates, which include zeolite; clays, and mixtures thereof.
In any aspect of the aforementioned beneficial agent delivery compositions, the binder, extrudate and / or particulate may have a characteristic dimension of from about 100 microns to about 3000 microns, from about 200 microns to about 2500 microns, from about 300 microns to about 2000 microns, from about 400 microns to about 1400 microns, or even from about 500 microns to about 1200 microns, where for said agglomerates and particulates the characteristic dimension is the average particle size of said agglomerates and particulates,
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and the characteristic dimension of the mentioned extruded products is the average diameter of the extruded products.
Beneficial Agent Delivery Composition 5 Aqlomerate / Particle / Extruded Product
Beneficial agent delivery compositions may be manufactured in accordance with the examples of the present specification and / or by the following process, which could comprise:
to. combine an encapsulated charitable agent; in one aspect, the encapsulated beneficial agent comprises a core and a shell that encapsulates the core; the core and / or shell of the encapsulated benefit agent comprise chelator; a chelator, a plasticizer and a binder to form a mixture;
b. combine the mixture with the dusting agent to form a material; and
c. removing a sufficient amount of plasticizer from the material to obtain a product comprising, based on the total weight of the product, from about 1% to about 50%, from about 2% to about 45%, from about 3% to about 40% , from about 4% to about 37%, from about 5% to about 35%, or even from about 6% to about 30% of plasticizer.
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Encapsulated Charity Agent <sup>L</sup> , .
The applicants recognized that the problems - associated with 'the incorporation of an encapsulated beneficial agent in a dry product, which includes the premature rupture of the encapsulated shell during the incorporation process, can be minimized when the encapsulated beneficial agent is further processed and it is incorporated into a chipboard which can then be added to a consumer product, such as a dry consumer product, which could be a particulate material, powder or other essentially dry form.
Useful encapsulating shell materials could comprise materials selected from the group consisting of polyethylenes, polyamides, polystyrenes, polyolsoprenes, polycarbonates, polyesters, polyacrylates, polyureas, polyurethanes, polyolefins, polysaccharides, epoxy resins, vinyl polymers, and mixtures thereof. In one aspect, useful wrapping materials include materials that are sufficiently impervious to the core material and materials in the environment in which the encapsulated benefit agent will be used, to enable the benefit of the supply to be obtained. Suitable waterproof envelope materials include materials selected from the group comprising reaction products of one or more amines with one or more aldehydes, such as formaldehyde or gluteraldehyde crosslinked urea, formaldehyde crosslinked melamine; gelatin-polyphosphate coacervates optionally crosslinked with gluteraldehyde; Jelly-gum arabic coacervates; silicone fluids
ΙΝ571Τ crosslinked; polyisocyanate reactive polyamine, and mixtures thereof? In one aspect, the wrapping material may comprise melarñTra * refTcula ^ a with formaldehyde.
The core of the encapsulated beneficial agent may comprise perfume raw material, silicone oils, waxes, hydrocarbon, higher fatty acids, essential oils, lipids, skin refreshers, vitamins, sunscreens, antioxidants, glycerin, catalysts, bleaching particles, particles. silicon dioxide, odor reducing agents, odor control materials, chelating agents, antistatic agents, softening agents, insect and moth repellent agents, colorants, antioxidants, chelators, thickening agents, droop and shape control agents, smoothing agents, wrinkle control agents, sanitizing agents, disinfecting agents, microbe control agents, control agents mold, antifungal agents, antiviral agents, drying agents, stain resistance agents, soil release agents, fabric freshening agents and freshness spreading agents, chlorine bleaching odor control agents, dye fixatives, dye transfer inhibitors, color keeping agents, optical brighteners, color restoration / rejuvenation agents, anti-fading agents, whiteness enhancers, anti-abrasive agents, wear resistance agents, fabric integrity agents, antiwear agents, agents to prevent the formation of pellets, defoaming and antifoaming agents, UV protection agents for fabrics and skin, sun-fade inhibitors, antiallergenic agents, enzymes, waterproofing agents, fabric softening agents, resistance agents shrinkage, stretch resistance agents, stretch-recovery agents, skin care agents, glycerin, and natural active substances, such as aloe vera, vitamin E, shea butter, cocoa butter and the like, polishes, antibacterial actives, antiperspirant actives, cationic polymers and mixtures thereof. In one aspect, the perfume raw material can be selected from the group consisting of alcohols, ketones, aldehyde, esters, ethers, nitriles, alkenes. In one aspect, the core material may comprise a perfume. In one aspect, said perfume could comprise perfume raw materials selected from the group consisting of alcohols, ketones, aldehydes, esters, ethers, nitrile alkenes, and mixtures thereof. In one aspect, said perfume may comprise a perfume raw material selected from the group consisting of perfume raw materials having a boiling point (BP) of less than about 250 ° C and a lower Clog P that approximately 3 perfume raw materials having a BP of more than approximately 250 ° C and a Clog P of more than approximately 3 perfume raw materials having a
BP of more than about 250 ° C and a Clog P less than 3, perfume raw materials having a BP less than about 250 ° C and a Clog P greater than about 3 and mixtures thereof. Perfume raw materials that have a boiling point BP less than about 250 ° C and a Clog P less than about 3 are known as Quadrant I perfume raw materials, perfume raw materials that have a BP of more than about 250 ° C and a Clog P of more than about 3 are known as Quadrant IV perfume raw materials, perfume raw materials having a BP of more than about 250 ° C and a Clog P less than about 3 are known as Quadrant II perfume raw materials, perfume raw materials having a BP less than about 250 ° C and a Clog P greater than about 3 are known as Quadrant III perfume raw materials. In one aspect, the perfume may comprise a perfume raw material having a BP less than about 250'C. In one aspect, the perfume may comprise a perfume raw material selected from the group consisting of Quadrant I, II, III perfume raw materials and mixtures thereof. In one aspect, the perfume may comprise a Quadrant III perfume raw material. Suitable raw materials for Quadrant I, II, III and IV perfumes are described in US Pat. USA no. 6,869,923 B1.
In one aspect, said perfume may comprise a Quadrant IV perfume raw material. Without wishing to be bound by theory, it is believed that Quadrant IV perfume raw materials can improve perfume odor balance. The perfume can comprise, on the basis
<img file="MX337136B_D0019.tif" />
of the total weight of the perfume, less than about 30%, less than about 20%, or even less than about 15% of the perfume raw material from Quadrant IV.
In one aspect, useful perfumes and / or flavorings include those listed in the following table:
3- (METHYLTIO) HEXANOL
1-BUTANOL, 2-METHYL1-BUTANOL, 3-METHYL1-ETHYL PROPIL ACETATE 1-HEXANOL, 2-ETIL1-HEXENOL
1-METOXI-4-PROPENYLBENZENE 1-METHYLBUTYL ACETATE 1-METHYL PROPYL ACETATE 1-OCTANOL
1- OCTEN-3-OL
2.4- DECADIENNIAL
2.4- DECADIENOATE
2.5- DIMETIL-4-HIDROXI-3- (2H) - FURANONA
2.5- DIMETILPIRAZINA -2,5-DIMETILPIRAZINA 2,6 DIMETIL- 5 HEPTENAL
2.6- DIMETILPIRAZINA -2,6-DIMETILPIRAZINA
2.6- NONADIENAL
2,6-NONADIENAL
2- FURANO ACETYL
2-ACETIL PIRIDINA -2-ACETIL PIRIDINA
2-ACETYLTIAZOLE
2-BUTHENAL
2-ETHYL-1- HEXANOL 2-HEXANOL
3-METHYL BUTYL ACETATE
3-METHYL BUTYL-2-METHYL BUTYRATE
3-METHYL PROPANAL
3- METHYLTIO-1-HEXANOL
4- ACETOXI-2,5-DIMETIL-3 (2H) -FURANONA
4-CARVOMENTANOL
4-METHYL-4-MERCAPTO-2-PENTANONE
4-METHYL-5-THIAZOLETHANOL
4-METHYLACETOPHENONE
4-TERPINEOL
METHYL 5 HEPTENE 2 ONA
NONEN 1 OL
6-METHILHEPT-5EN-2-ONA
A-AMYL CINAMIC ALDEHYDE
A-BISABOLENE
ACETAL
ACETALDEHlDO
ACETIC ACID
ACETIC ACID, 2-PHENYLEYLESTER ACETOPHENONE
ACETOXi-FURANEOL (4-ACETOXI-2,5-DIMETHYL (2H) -FURANONE)
ACETYL METHYL CARBINOL
ACETYLPROPIONYL
ALDEHYDE C12
ALDEHYDE C16
ALYLUM CAPROATE
ALIL CYCLOHEXANOPROPIONATE
ALFA - IRONA
<img file="MX337136B_D0020.tif" />
<img file="MX337136B_D0021.tif" />
2-ISOPROPIL-4-METHYLTIAZOLE
2-METOXI-3-METHYLPIRAZINE
-2-METOXI-3-METHYLPIRAZINE
2-METOXI-4-ALYLPHENOL
2-METOXIFENOL
2-METHYL BUTANOL
2-METHYL BUTYL ACETATE
2-METHYL PENTENOIC ACID (STRAWBERIFF)
2-METHYL PROPIL ACETATE
2-METHYL-1-PROPANOL
2-METHYL-3- (P-METHYL PHENYL) PROPANAL
2-METHYL-4-PROPIL-1,3-OXATIAN
2-METHYL BUTANOIC ACID
2-METHYL BUTYL ACETATE
2-METHYLBUTYRIC ACID
2-METHYLPENT-2-ENAL (TRANS)
2-METHYLPROPANOL
2-METHYLPROPIL CAPROATE (ISOBUTIL CAPROATO)
2-METHYLTETRAHYDROFURANE-3-ONA
2-PHENYLETHANOL
2-PROPENOIC ACID, ETHYL ESTER
2- PROPENYL HEXANOATE
3- (METHYLTIO) -1-PROPANOL
3,4-DIHYDROCUMARINE
3,5,5-TRIMETIL HEXANAL
3-METHYL BUTANAL
3-METHYL BUTYL ACETATE
3-METHYBUTANOL
BETA-PINENO
BUTANAL
BUTANOIC ACID, 2-METHYL-, ETHYLESTER BUTANOIC ACID, METHYL ESTER BUTANOL
BUTYL ACETATE
BUTIL BUTIRATO
BUTIL CAPROATO
BUTIL HEXANOATE
BUTYL PROPIONATE
ALPHA-IONONA
ALPHA-IRONA
ALPHA-METHYL BENCIL
ALFA-PINENO
ALPHA-TERPINEOL
AMBRETTOLIDE
A-METHYL BENZYL PROPIONATE AMYL ACETATE AMYLCINAMIC ALDEHYDE AMYL ISOVALERATE AMYL PROPIONATE AMYL VALEATE ANALSIC ALDEHYDE ANISYL ACETONE ANISYL ACETONE A-PINENE
ARUSCOL FIRMENICH
B-CARIOPHYLENE
BENZALDEHYDE
BENCILO ACETATE
BENZYL ALCOHOL
BENZYL ALCOHOL
BENCILO CINAMATE
BENCILO PROPIONATE
BETA DAMASCENONA
BETA.-DAMASCENONA
BETA-DAMASCONA
BETA-IONONA
ETHYL BUTRATE
ETHYL CAPRYLATE (OCTANOATE)
ETHYL CINAMATE
ETHYL DODECANOATE
ETHYL HEXANOATE
ETHYL ISOBUTYRATE
ETHYL ISOVALERIANATE
LACTATE OF
ETIL MALTOL
ETIL MALTOL ™
BUTIRIC ACID
Caproic acid (hexanoic) CAPRILIC ACID CARIOPHYLENE OXIDE CINAMIC ALDEHYDE CIS-3-HEXENOL
CIS-3-HEXENYL 2 METHYL BUTYRATE CIS-3-HEXENYL ACETATE CIS-3-HEXENYL ACETATE
CIS-3- HEXENYL BUTYRATE CIS-3-HEXENYL FORMAT CIS-3-HEXENYL LACTATE CIS-3-HEXENYL-2-METHYL BUTYRATE CIS-5-OCTENYL PROPIONATE CIS-6-NONENOL CIS-JASMONA
CIS-PARA-MENTA-8-TIOL-3-ONA (TIOMENTONA)
CITRAL
CITRONELOL
CITRONELOL
CITRONELYL FORMAT CITRONELYL PROPIONATE CYCLAMEN ALDEHYDE CYCLOTENE ™
CIMENO
DAMASCENONA
CHANNEL
DECANOIC ACID
DECANOL
DELTA - DODECALACTONE
DELTA DECALACTONE
DELTA OCTALACTONE
DELTA UNDECALACTONE
DELTA-DODECALACTONE
DIACETILE
DIACETILE
DIMETHYL ANTRANYLATE
INSTIT
Ci
ETHYL NONANOATE
ETHYL OCTANOATE
ETHYL OCTANOATE
ETHYL OXYHYDRATE
ETHYL PELARGONATE (NONANOATE) ETHYL PROPIONATE ETHYL PROPIONATE ETHYL VALERATE
3-ETOXI-4-HYDROXYBENZALDEHYDE (ETHYLVAINILLIN)
ETHYL (METHYLTIO) ACETATE
ETIL-2,5- (2,6) DIMETILPIRAZINA
2-ETHYL METHYLBUTYRATE
ETIL-3 (METHYLTIO) PROPIONATE
ETIL-3-METHYL BUTYRATE
ETIL-3-METHYL BUTYRATE
ETHYLPHENYL ACETATE
FURANEOL ™
GALBANOLENE SUPER
GAMMA HEPTALACTONE
GAMMA-HEXALACTONE
GAMMA NONALACTONE
GAMMA OCTALACTONE
UNDECALACTONE GAMMA
GAMMA.-TERPINENE
GAMMA-DECALACTONE
GAMMA-DODECALACTONE
GAMMA-METHYLIONONE
GERANIOL
GERANYL ACETATE
GERANILO BUTRATE
GERANILO FORMAT
GERANILO PROPIONATE
GLACIAL ACETIC ACID
G-TERPINENE
HEDIONE
HELIOTROPINE
HEXANAL
DIMETHYL SULFIDE
D-LIMONENE
DODECANAL
Dodecanoic acid
ETHYL ACETATE
ETHYL PENTANOATE
ETHYL 3- (METHYLTIO) PROPANOATE
ETHYL ACETOACETATE
ETHYL ACRYLATE
ETHYL ANTRANYLATE
ETHYLBENZOATE
IRISONA-ALPHA
ISOAMYL ACETATE
ISOAMLLIC ALCOHOL
ISOAMIL BUTIRATO
ISOBORNIL ACETATE
ISOBUTYL ACETATE
ISOBUTYL ACETATE
ISOBUTYL BUTENOATE
ISOBUTYL CAPROATE
ISOBUTIL ISOVALERATO
ISOBUTYL PHENYLACETATE
ISOPROPIL-4-METHYLTIAZOLE
ISOPULEGOL
ISOVALERALANIC ALDEHYDE
LAURINA
L-CARVONA
LINALOL
LINALOL OXIDE LINALYL ACETATE LINALYL CINAMATE LINALYL PROPIONATE
3-LYLINYL METHYLBUTYRATE L-MENTONA MALTOL
MALTOL ™
MELONAL ™ (EQUAL TO A18) METOXI FENIL BUTANONA
Hexanoic acid
Hexanoic acid, methyl ester
HEXANOL
Hexenyl ΗΕΧΑΝΟΑΤΟ Hexyl acetate ALCOHOL hexyl hexyl BUTYRATE hexyl VALERATE 2-methylbutyrate, hexyl hydroxycitronellal hydroxyacetophenone palmitic acid FOR-cymene pentanoic acid phenoxy ethyl propionate PHENYL ACETALDEHlDO phenylethanol PHENYL ETHYL ACETATE phenylethyl tiglate phenylethyl acetate phenylethyl methyl ether p-mentha-3-one -8-THYOLACETATE PRENOL
PRENYL ACETATE PROPANOL |
Propionic acid PROPYL ACETATE PROPYLENE GLYCOL
SUCCESS
SULFOX FIRMENICH
TERPENYL ACETATE TIAZOL, 2-ETHYL-4-METHYLTIAZOLE, 4-ETHYL-2-PROPYL TIOMENTONE TIOMENTONE ACETATE TRANS-2-CIS-6-NONADIEN-1-OL TRANS-2-DECEN-1-AL TRANS-2-HEXENAL
METHYL 3 (METHYLL) PROPIONATE METHYL AMYLKETONE METHYLTRANYLATE METHYL BUTYRATE METHYL KINAMATE METHYL HEPTINE CARBONATE METHYL HETYL KETONE METHYL THYBUTYRATE METHYL THYHEXANOL
METHYL VINYLTIAZOLE
-METHYL VINYLTIAZOLE METHYL-2- (METHYLTH) ACETATE
2- METHYL METHYLBUTYRATE METHYL-2-OCTINOATE
METHYL 3-METHYLTIOPROPIONATE
3- METHYL METHYLPHENYL HEXENAL NONENOATE (COCAL ™) METHYL METHYL BUTYRATE OCTIL ACETATE
OXANONE ™
<img file="MX337136B_D0022.tif" />
TRANS-2-HEXENAL
TRANS-2-HEXENOIC ACID
TRANS-2-HEXENOL
TRANS-2-HEXENYLACETATE
TRANS-3-HEXENOIC ACID
TRIACETINE
-TRIMETILOXAZOLE
TRIMETILOXAZOLE
Trimethylpyrazine
-TRIMETHYLPIRAZINE
4-HYDROXY-3-METOXYBENZALDEHYDE (VANILLIN)
MYCENE
NATACTONE FIMENICH
N-BULIRALDEHYDE
NEROL
NERYL ACETATE
NONANOL
N-VALERILALDEHlDO
OCIMENE (TRANS)
OCTANAL
OCTANOIC ACID
Suitable perfumes for use in the present invention include the following:
<td>CAS</td><td>P&G name</td><td>Chemical name</td>
<td> 7540-51-4</td><td>BARANOL</td><td>(-) - Cltronelol</td>
<td> 2216-51-5</td><td>MENTHOL</td><td>(-)-Menthol</td>
<td> 16356-11-9</td><td>GALBANOLENE SUPER</td><td>(3E, 5Z) -1,3,5-Undecatriene</td>
<td> 557-48-2</td><td>E, Z-2, 6-NONADIEN-1-AL FCC</td><td>(E) -2, (Z) -6-Nonadienal</td>
<td> 3239-35-8</td><td>TANGERINOL</td><td>(E) -5-Tangerinol</td>
<td> 3239-37-0</td><td>TANGERINOL</td><td>(Z) -5-Tangerinol</td>
<td> 6790-58-5</td><td>AMBROFIX</td><td>[3aR- (3aa, 5ab, 9aa, 9bb)] - dodecahydro- 3a, 6,6,9a-tetramethylnaphtho [2,1-b] furan</td>
<td> 13851-11-1</td><td>FENQUILO / SUPER ACETATE</td><td>1,3,3-trimethyl-2-norbornanllo acetate</td>
S0118-06-5
ISOPENTRATE
112-45-8
UNDECILENIC ALDEHYDE
53179-04-7
FLORIDILE
112-30-1
RHODALIONE
2442-10-6
106-02-5
AMYL VINYL CARBINYL ACETATE
CANOLID CYCLE
Τ tt 7 ll · ''
TT, Τ '»¡
1,3-Dlmethyl-3-butenyl isobutyrate
10-Undecennial
10-undecenonitrile
1-Decanol
1-Octen-3-yl acetate
-Oxacyclohexadecan-2-one
128-51-8
37172-02-4
58039-49-6
141-13-9
13254-34-7
7786-44-S
23696-85-7
28219-61-6
137-03-1
24168-70-5
1205-17-0
543-39-5
110-41-8
2463-53-8
4819-67-4
103-60-6
103-45-7
14765-30-1
6784-13-0
7775-00-0
58430-94-7
106-21-8
67801-20-1
55066-49-4
20407-84-5
18127-01-0
18096-62-3
4621-04-9
NOPILO ACETATE
DIHIDRO AMBRATO
CYCLE C
ADOXAL
DIMETIL-2 6-HEPTAN-2-OL
2, 6-NONADIEN-1-OL
DAMASCENONA
DARTANOL
FLEURAMONA
METOXYISOBUTILPIRAZINA @ 0.1% MPG FP246
HELIONAL
MIRCENOL SUPER 13.2193 (CONF.-IFF)
METHYLONYLACETALDEHYLDE
NONEN-1-AL
DELPHONE
PHENOXY ETHYL ISOBUTYRATE
PHENYL ETHYL ACETATE
2-SEC-BUTYL CYCLOHEXANONE
LIMINAL 955374
CYCLEMAX
ISONONYL ACETATE
DIMETILOCTAN
EBANOL
MEFRANAL
MANDARIN ALDEHYDE 10% IN CITRATE
BOURGEONAL
CRIST. INDOFLOR
ROSELEA
1R - (-) - Nopil Acetate
2- (sec.butyl) -1-vinylcyclohexyl acetate
2,4-Dimethyl-3-Cyclohexene-1-carboxaldehyde
2,6,10-T rimethyl-undec-9-enal
2,6-Dimethyl-2-heptanol
2,6-Nonadien-1-ol
2-Buten-1-one, 1- (2,6,6-trimethyl-1,3cyclohexadien-1-yl) 2-Etyl-4- (2,2,3-trimethylcyclopent-3-enyl- 1) -2buten-1-ol
2-Heptylcyclopentanone
2-Methoxy-3- (1-methylpropyl) pyrazine
2-Methyl-3- (3,4-methylenedioxyphenyl) -propanal
2-Methyl-6-methyl-7-octen-2-ol
2-Methylundecanal
2- Nonen-1-al
2-Pentylcyclopentanone
2-Phenoxlethyl isobutyrate
2-Phenylethyl acetate
2-sec. Butyl cyclohexanone
3- (4-Methylcyclohex-3-en-1-l) -buliraldehyde
3- (p-lsopropylphenyl) propionaldehyde
3,5,5-Trimetllhexll acetate
3,7-dimet I-1 -octanol
3-Methyl-5- (2,2,3-trimethyl-3-cyclopenten-1l) pent-4-en-2-ol
3-Methyl-5-phenyl-1-pentanal
3-Nonilacrolein
4- (1,1-dimethyl ethyl) benzenepropanal
4,4a, 5,9b-tetrahydrodiene [1,2-d] -1,3-dioxin
4-lsopropylcyclohexanol
13171-00-1
ALMIZCLE INDANONA
4-Acetyl-6-t-butyl-1,1-dimethylindane sa:
<sup>29</sup> INPUT iNonTU ':: · z -'-' · '.....
GIVE IT the '··' '.'. 7
<td> 122-00-9</td><td>PARA-METHYLACETHOPHENONE</td><td>4-Methylacetophenone</td>
<td rowspan="2"> 562-74-3</td><td rowspan="2">TERPINENOL-4</td><td></td>
<td>4-Teipinenul ....... »—— ···</td>
<td> 32210-23-4</td><td>4 - TER-BUTYLCYCLOHEXYL ACETATE</td><td>4-tert-butylcyclohexyl acetate</td>
<td> 16587-71-6</td><td>ORIVONA</td><td>4-tert-amylcidohexanone</td>
<td> 37609-25-9</td><td>5-CYCLOHEXADECEN-1-ONA</td><td>5-Cyclohexadecenone</td>
<td> 22457-23-4</td><td>STEMONA</td><td>5-Methyl-3-heptanone oxime</td>
<td> 32764-98-0</td><td>JASMOLACTONE</td><td>6- (Z, 3-Pentenyl) -tetrahydro- (2H) -pyranone-2</td>
<td> 33885-51-7</td><td>PINE ACETALDEHYDE</td><td>6,6-dimethyl-2-norpinene-2-propionaldehldo</td>
<td> 70214-77-6</td><td>NONADIL</td><td>6,8-Diethyl-2-nonanol</td>
<td> 65442-31-1</td><td>ISOBUTYL QUINOLINE</td><td>6-isobutylquinoline</td>
<td> 135-79-5</td><td>ISOPROPYLQUINOLINE</td><td>6-lsopropylquinoline</td>
<td> 91-62-3</td><td>PARA-METHYLQUINOLINE</td><td>6-Methylquinoline</td>
<td> 1506-02-1</td><td>AMTOLIDE</td><td>7-Acetyl-1,1,3,4,4,6-hexamethyltetralin</td>
<td> 84697-09-6</td><td>TBHQ CHANNEL</td><td>Acalea</td>
<td> 100-06-1</td><td>PARAMETOXI ACETOF / BENZ / SALIC MX</td><td>Acetoanisole</td>
<td> 98-86-2</td><td>ACETOPHENONE</td><td>Acetophenone</td>
<td> 67634-00-8</td><td>ALYLAMYL GLYCOLATE</td><td>Allyl amyl glycollate</td>
<td> 123-68-2</td><td>ALILO CARROATE</td><td>Allyl caproate</td>
<td> 2705-87-5</td><td>ALYL CYCLOHEXANOPROPIONATE</td><td>Ally cyclohexyl propionate</td>
<td> 142-19-8</td><td>ALYL HEPTANOATE 97 +% FCC</td><td>allyl heptanoate</td>
<td> 7493-74-5</td><td>ALIL FENOXI ACETATE</td><td>allyl phenoxy acetate</td>
<td> 67634-15-5</td><td>FLORALOZONA</td><td>alpha, alpha-dimethyl-p-ethylphenylpropanal</td>
<td> 122-40-7</td><td>AMYLCINAMIC ALDEHYDE</td><td>alpha-Amylcinamaldehyde</td>
<td> 60763-41-9</td><td>AMYL CINAMIC ALDEHYDE DI ETHYL ACETAL</td><td>alpha-amylcinamaldehyde diethyl acetal</td>
<td> 17627-44-0</td><td>BISABOLENE</td><td>alpha-Bisabolene</td>
<td> 24720-09-0</td><td>ALFA DAMASCONA</td><td>alpha-damascone</td>
<td> 502-61-4</td><td>BISABOLENE</td><td>alpha-farnesene</td>
<td> 101-86-0</td><td>HEXYLKINAMIC ALDEHYDE</td><td>alpha-hexylzinemaldehyde</td>
<td> 127-41-3</td><td>IONONAAB</td><td>alpha-ionone</td>
<td> 79-69-6</td><td>REFINED ALPHA-IRONA</td><td>alpha-lrona</td>
<td> 127-51-5</td><td>GAMMA METHYL IONONA</td><td>alpha-isomethylionone</td>
<td> 98-55-5</td><td>ALPHA-TERPINEOL</td><td>alpha-terpineol</td>
<td> 80-26-2</td><td>LINDENYL-ACETATE</td><td>alpha-terpinyl acetate</td>
<td> 2050-08-0</td><td>AMYL SALICYLATE</td><td>amyl salicylate</td>
<td> 189440-77-5</td><td>ANAPEAR 8753453</td><td>Anapear</td>
<td> 104-21-2</td><td>ANISYL ACETATE</td><td>Anisyl acetate</td>
<td> 25225-08-5</td><td>AFERMATO</td><td>Afermatous</td>
<img file="MX337136B_D0023.tif" />
<img file="MX337136B_D0024.tif" />
<td> 89-43-0</td><td>AURANTIOL</td><td>Aurantiol ................</td>
<td> 362467-67-2</td><td>AZURONE 10 0015573</td><td>Azurone</td>
<td> 100-52-7</td><td>BENZALDEHYDE</td><td>Benzaldehyde</td>
<td> 119-61-9</td><td>BENZOPHENONE</td><td>Benzophenone</td>
<td> 140-11-4</td><td>BENCILO ACETATE</td><td>Benzyl acetate</td>
<td> 100-51-6</td><td>BENZYL ALCOHOL</td><td>Benzyl alcohol</td>
<td> 120-51-4</td><td>BENZYL BENZOATE</td><td>Benzyl benzoate</td>
<td> 103-37-7</td><td>BENCIL BUTRATE</td><td>Benzyl butyrate</td>
<td> 103-41-3</td><td>BENCILO CINAMATE</td><td>Benzyl cinnamate</td>
<td> 100-86-7</td><td>DIMETHYLBENCILCARBINOL</td><td>Benzyl dimethylcarbinol</td>
<td> 103-28-6</td><td>BENCILO ISOBUTYRATE</td><td>Benzyl isobutyrate</td>
<td> 122-63-4</td><td>BENCILO PROPIONATE</td><td>Benzyl propionate</td>
<td> 118-58-1</td><td>BENCILO SALICYLATE</td><td>Benzyl salicylate</td>
<td> 2550-26-7</td><td>BENCIL ACETONE</td><td>Benzyl ketone</td>
<td> 103-05-9</td><td>PHENYL ETHYLIMETILCARBINOL</td><td>Benzyl-tert-butanol</td>
<td> 23267-57-4</td><td>BETA-IONONE EPOXIDE</td><td>Beta-ionone epoxide</td>
<td> 103-64-0</td><td>BROM STYROL</td><td>beta-bromostylol</td>
<td> 87-44-5</td><td>EXTRA CARIOPHYLENE</td><td>beta-caryophyllene</td>
<td> 23726-91-2</td><td>BETA DAMASCONA</td><td>beta-damascone (configuration E)</td>
<td> 18794-84-8</td><td>BISABOLENE</td><td>beta-farnesene</td>
<td> 185429-83-8</td><td>GEORGYWOOD (CONF.-GIV)</td><td>beta-Georgywood</td>
<td> 14901-07-6</td><td>BETA-IONONA 97 +% FCC (CONF.-ALDRICH)</td><td>beta-ionone</td>
<td> 123-35-3</td><td>MIRCENO</td><td>beta-myrcene</td>
<td> 127-91-3</td><td>BETA-PINENO</td><td>beta-pinene</td>
<td> 72429-08-4</td><td>BIGARADE OXIDE</td><td>Bigarade oxide</td>
<td> 495-62-5</td><td>BISABOLENE</td><td>Bisabolene</td>
<td> 58567-11-6</td><td>BOISAMBRENE FORTE (S 506)</td><td>Boisambrene forte</td>
<td> 24717-86-0</td><td>OPEN CN (C SYN)</td><td>Isobutyrate bornyl</td>
<td> 3155-71-3</td><td>BORONAL</td><td>Boronal</td>
<td> 72089-08-8</td><td>BRAHMANOL F / 3/071130</td><td>Brahmanol</td>
<td> 75147-23-8</td><td>BUCOXIME</td><td>Bucoxima</td>
<td> 136-60-7</td><td>BUTYL BENZOATE</td><td>Butyl benzoate</td>
<td> 128-37-0</td><td>TOLUENE HYDROXYBUTYLATE</td><td>Butylated hydroxytoluene</td>
<td> 79-92-5</td><td>CANPHENE</td><td>Camphene</td>
<td> 76-22-2</td><td>CAMPHOR RUBBER</td><td>Camphor</td>
<td> 5462-06-6</td><td>CANTOXAL (03-0952)</td><td>Cantoxal</td>
<td> 112-31-2</td><td>DECLIC ALDEHYDE</td><td>Capraldehyde</td>
<img file="MX337136B_D0025.tif" />
<td> 111-87-5</td><td>OCTYL ALCOHOL</td><td>Caprylic alcohol</td>
<td> 124-13-0</td><td>OCTIL ALDEHYDE</td><td>Caprolic aldehyde</td>
<td> 33704-61-9</td><td>CASHMERAN</td><td>Cashmeran</td>
<td> 77-53-2</td><td>CEDROL</td><td>Cedrol</td>
<td> 77-54-3</td><td>CEDAC</td><td>Cedar Acetate</td>
<td> 19870-74-7</td><td>METHYL Ether Ether</td><td>Cedril methyl ether</td>
<td> 3720-16-9</td><td>LIVESCONA</td><td>Celery ketone</td>
<td> 6707-60-4</td><td>12 OXAHEXADECECOLOLIDE</td><td>Cervolide</td>
<td> 79-78-7</td><td>HEXALON</td><td>Ketone V</td>
<td> 88-04-0</td><td>4-CHLORINE 3.5 XYLENOL</td><td>Cioroxilenol</td>
<td> 1885-38-7</td><td>CINNAMALVA</td><td>Cinnamalva</td>
<td> 104-54-1</td><td>CINAMIC ALCOHOL</td><td>Cinnamic alcohol</td>
<td> 104-55-2</td><td>CINAMIC ALDEHYDE</td><td>Cinnamic aldehyde</td>
<td> 103-54-8</td><td>CINAMYL ACETATE</td><td>Cinnamyl acetate</td>
<td> 53046-97-2</td><td>3.6-NONADIEN-1-OL</td><td>cis-3, cis-6-nonadienol</td>
<td> 928-96-1</td><td>BETA GAMMA HEXENOL</td><td>cis-3-Hexen-1-ol</td>
<td> 53398-85-9</td><td>CIS-3-HEXENYL ALPHA METHYL BUTYRATE</td><td>cis-3-Hexenyl 2-methyl butyrate</td>
<td> 3681-71-8</td><td>OIS 3 HEXENYL ACETATE</td><td>cis-3-Hexenyl acetate</td>
<td> 25152-85-6</td><td>CIS- 3- HEXENIL BENZOATE</td><td>cis- 3- hexenyl benzoate</td>
<td> 16491-36-4</td><td>CIS 3 HEXENIL BUTIRATO</td><td>cis- 3- Hexenyl butyrate</td>
<td> 65405-77-8</td><td>CIS-3-HEXENIL SALICILATO</td><td>cis-3-Hexenyl salicylate</td>
<td> 67883-79-8</td><td>CIS-3-HEXENIL TIGLATE</td><td>cis-3-hexenyl tiglate</td>
<td> 36508-31-3</td><td>CIS-ISO-AMBRETÓLIDO</td><td>cis-iso-ambretolide</td>
<td> 488-10-8</td><td>CIS-JASMONA</td><td>cis-Jasmona</td>
<td> 5392-40-5</td><td>CITRAL</td><td>Citral</td>
<td> 7549-37-3</td><td>CITRAL DIMETHYLACETAL</td><td>Citral dimethylacetal</td>
<td> 106-23-0</td><td>CITRONELAL</td><td>Citronelal</td>
<td> 106-22-9</td><td>CITRONELOL</td><td>Citronellol</td>
<td> 150-84-5</td><td>CITRONELIL ACETATE</td><td>Citronellyl acetate</td>
<td> 105-85-1</td><td>CITRONELYL FORMAT</td><td>Citronellyl formate</td>
<td> 51566-62-2</td><td>BARANYL NITRILO</td><td>Citronellyl nitrite</td>
<td> 141-14-0</td><td>CITRONELIL PROPIONATE</td><td>Citronellyl propionate</td>
<td> 7492-67-3</td><td>CITRONELIL OXIACETALDEHlDO</td><td>Citronellyl oxyacetaldehyde</td>
<td> 97384-48-0</td><td>CITROWANIL B</td><td>Citrowanil B</td>
<td> 6819-19-8</td><td>CITRIL ACETATE</td><td>Citril acetate</td>
<td> 83926-73-2</td><td>CORANOL (CONF.-FIRM)</td><td>Coranol</td>
<td> 91-64-5</td><td>Coumarin</td><td>Coumarin</td>
<img file="MX337136B_D0026.tif" />
<td> 122-03-2</td><td>CUMINIC ALDEHYDE</td><td>Cuminaldehyde</td>
<td> 13816-33-6</td><td>NITRILE CUMIN</td><td>Cuminil nitrile</td>
<td> 67634-20-2</td><td>CYCLABUTE</td><td>Cyclabute</td>
<td> 103-95-7</td><td>CIMAL</td><td>Cyclamen aldehyde</td>
<td> 68991-97-9</td><td>MELAFLEUR MO9962</td><td>Ciclemone A</td>
<td> 54982-83-1</td><td>ZENOLIDE</td><td>Cyclic ethylene dodecanedioate</td>
<td> 113889-23-9</td><td>CYCLOBUTANATE 081145</td><td>cyclobutanate</td>
<td> 68901-15-5</td><td>CYCLOGALBANATE</td><td>Cycloalbanato</td>
<td> 22471-55-2</td><td>THESARON</td><td>cyclohexanecarboxylic acid ,. 2,2,6-t rimethyl-, ethyl ester, (1R, 6S) -rel-</td>
<td> 25485-88-5</td><td>CYCLLOHEXYL SALICYLATE</td><td>Cyclohexyl salicylate</td>
<td> 21722-83-8</td><td>CYCLLOHEXYL ETHYL ACETATE</td><td>Cyclohexylethyl acetate</td>
<td> 84560-00-9</td><td>CYCLOPENTOL</td><td>Cyclopentol</td>
<td> 40203-73-4</td><td>CYCLOPIDENE 937160</td><td>Cyclopentylidene acetic acid, methyl ester</td>
<td> 68039-69-0</td><td>DATILAT</td><td>Datilat</td>
<td> 5454-19-3</td><td>N-DECIL PROPIONATE</td><td>Decyl propionate</td>
<td> 13019-22-2</td><td>ROSALVA</td><td>Dekylenic alcohol</td>
<td> 57378-68-4</td><td>DELTA DAMASCONA</td><td>delta-damascone</td>
<td> 705-86-2</td><td>DECALACTONE</td><td>delta- decalactone</td>
<td> 82356-51-2</td><td>DELTA MUSCENONA 962191</td><td>Delta-muscenone</td>
<td> 431-03-8</td><td>DIACETILE 0.1% IN DFG</td><td>Diacetyl</td>
<td> 105-53-3</td><td>DIETHYL MALONATE</td><td>Diethyl malonate</td>
<td> 84-66-2</td><td>DI ETI LO PHTHALATE</td><td>Diethyl phthalate</td>
<td> 37172-53-5</td><td>DIHIDRO ISO JASMONATO</td><td>Dihydro isojasmonate</td>
<td> 498-81-7</td><td>DIHYDROTERPINEOL</td><td>Dihydroterpineol</td>
<td> 17283-81-7</td><td>DIHIDRO BETA-IONONA</td><td>Dihydro-beta-ionone</td>
<td> 119-84-6</td><td>DHIDROCUMARINE</td><td>Hydrocoumarin</td>
<td> 64001-15-6</td><td>DIHIDRO CYCLACET</td><td>Dihydro cyclacet</td>
<td> 2785-87-7</td><td>DIHIDRO EUGENOL</td><td>Dihydroeugenol</td>
<td> 1128-08-1</td><td>DIHIDROJASMONA</td><td>Dihydrojasmona</td>
<td> 8479-58-8</td><td>DIMIRCETOL</td><td>Dihydromyrcenol</td>
<td> 80-25-1</td><td>MENTANIL ACETATE</td><td>Dihydroterpenyl acetate</td>
<td> 85-91-6</td><td>DIMETHYL ANTRANYLATE</td><td>Dimethyl anthranilate</td>
<td> 151-05-3</td><td>DIMETHYLBENCILCARBINYL ACETATE</td><td>Dimethylbenzylcarbinyl acetate</td>
<td> 10094-34-5</td><td>DIMETHYLBENCILCARBINYL BUTYRATE</td><td>Dimethylbenzylcarbinyl butyrate</td>
<td> 103-05-9</td><td>BENIL ETHYLIMETILCARBINOL</td><td>phenyl ethyldimethylcarbinol</td>
<td> 138-86-3</td><td>DIPENTENE</td><td>Dipentene</td>
<td> 101-81-5</td><td>Diphenylmethane</td><td>Diphenylmethane</td>
<img file="MX337136B_D0027.tif" />
INSTITUTE OF THE
IN
<img file="MX337136B_D0028.tif" />
<td rowspan="2"> 101-84-8</td><td rowspan="2">DIPHENYL OXIDE</td><td>Diphenyloxide</td>
<td></td>
<td> 25265-71-8</td><td>ABSOLUTE VANILLA 50 DFG 99FP / 1133 (CFR)</td><td>Dipropylene glycol</td>
<td> 89-48-5</td><td>MENTILE ACETATE 620020</td><td>dl-menthyl acetate</td>
<td> 2556-10-7</td><td>HYACINTH BODY 08-8735</td><td>Efetaal</td>
<td> 40910-49-4</td><td>ELINTAAL FORTE</td><td>Elintaal</td>
<td> 140-67-0</td><td>EX BADIANE ESTRAGOL</td><td>Estragol</td>
<td> 6413-10-1</td><td>690965 JASMAPRUNAT</td><td>Ethyl 2-methyl-1,3-dioxolane-2-acetate</td>
<td> 7452-79-1</td><td>ETIL-2-METHYL BUTYRATE</td><td>Ethyl 2-methylbutyrate</td>
<td> 101-97-3</td><td>ETHYL PHENYLACETATE</td><td>Ethyl 2-phenylacetate</td>
<td> 5405-41-4</td><td>ETIL-3-HIDROXI BUTIRATO</td><td>Ethyl 3-hydroxy butyrate</td>
<td> 121-39-1</td><td>ETHYLPHENYL GLYCIDATE</td><td>Ethyl 3-phenylglycidate</td>
<td> 141-78-6</td><td>ETHYL ACETATE</td><td>Ethyl acetate</td>
<td> 141-97-9</td><td>ETHYL ACETOACETATE</td><td>Ethyl acetoacetate</td>
<td> 589-98-0</td><td>OCTANOL-3</td><td>Ethyl amyl carbinol</td>
<td> 106-68-3</td><td>ETIL AMIL CETONA</td><td>Ethyl amyl ketone</td>
<td> 35044-59-8</td><td>ETIL SAFRANATO</td><td>Ethyl beta safranate</td>
<td> 105-54-4</td><td>ETHYL BUTRATE</td><td>Ethyl butanoate</td>
<td> 103-36-6</td><td>ETHYL CINAMATE</td><td>Ethyl cinnamate</td>
<td> 106-30-9</td><td>ETIL OENANTATE</td><td>Ethyl Heptoate</td>
<td> 123-66-0</td><td>ETIL CAPROATO FCC (GIVAUDAN)</td><td>Ethyl hexanoate</td>
<td> 925-78-0</td><td>ETHYHEXYL KETONE</td><td>Ethylhexyl ketone</td>
<td> 10339-55-6</td><td>ETIL LINALOL</td><td>Ethyl linalol</td>
<td> 4940-11-8</td><td>ETIL MALTOL</td><td>Ethyl Maltol</td>
<td> 77-83-8</td><td>ETHYL METHYL PHENYL GLYCIDATE</td><td>Ethyl methylphenylglycidate</td>
<td> 105-37-3</td><td>ETHYL PROPIONATE</td><td>Ethyl propionate</td>
<td> 118-61-6</td><td>ETHYL SALICYLATE</td><td>Ethyl salicylate</td>
<td> 3025-30-7</td><td>ETHYL 2,4-DECADIENOATE</td><td>Ethyl trans-2, cis-4-decadienoate</td>
<td> 121-32-4</td><td>ETHYL VANILLINE</td><td>Ethyl vanillin</td>
<td> 105-95-3</td><td>ETHYLENE BRASILATE</td><td>Ethylene brassylate</td>
<td> 470-82-6</td><td>EUCALIPTOL</td><td>Eucalyptol</td>
<td> 97-53-0</td><td>EUGENOL</td><td>Eugenol</td>
<td> 14595-54-1</td><td>EXALTENONE 942008</td><td>Exaltenone</td>
<td> 4602-84-0</td><td>FARNESOL</td><td>Farnesol</td>
<td> 1632-73-1</td><td>PENCHLYL ALCOHOL</td><td>Phenolic alcohol</td>
<td> 81925-81-7</td><td>FILBERTONE 1% IN TEC 736664</td><td>Filbertone G</td>
<td> 134123-93-6</td><td>FLEURANIL</td><td>Fleuranyl</td>
<td> 67634-26-8</td><td>FLORALATE 062960</td><td>Floralate</td>
<img file="MX337136B_D0029.tif" />
<img file="MX337136B_D0030.tif" />
-i
Ρ) ιτ .¡Γ 1
<img file="MX337136B_D0031.tif" />
<td> 67634-25-7</td><td>FLORALATE 062960</td><td>Floralate • ..ν ·. · ^ · * 4-οΐΛ £ ^ σίΐΛ / «· ΛΛΜ · .ο., - <.;</td>
<td> 125109-85-5</td><td>FLORHIDRAL</td><td>Florhidral</td>
<td> 63500-71-0</td><td>FLOROL</td><td>Florosa Q</td>
<td> 80657-64-3</td><td>FRUITATE</td><td>Fruitate</td>
<td> 35206-51-0</td><td>FRUTINAT 611 400</td><td>Frutinat</td>
<td> 69300-15-8</td><td>FRUTONILE</td><td>Frutonile</td>
<td> 1222-05-5</td><td>GALAXOLIDE 50% CITROFLEX (C IFF)</td><td>Galaxolide</td>
<td> 35087-49-1</td><td>GAMMA DAMASCONA 944580</td><td>gamma- Damascona</td>
<td> 706-14-9</td><td>GAMMA-DECALACTONE</td><td>gamma-Decalactone</td>
<td> 2305-05-7</td><td>DECALACTONE</td><td>gamma-dodecalactone</td>
<td> 695-06-7</td><td>GAMMA-HEXALACTONE</td><td>gamma-hexalactone</td>
<td> 104-61-0</td><td>NONALACTONE</td><td>gamma-Nonalactone</td>
<td> 104-50-7</td><td>GAMMA OCTALACTONE FCC</td><td>gamma-Octalactone</td>
<td> 104-67-6</td><td>PEACH ALDEHYDE COEUR</td><td>gamma-Undecalactone (racemic)</td>
<td> 105-87-3</td><td>GERANYL ACETATE</td><td>Geranyl acetate</td>
<td> 106-29-6</td><td>GERANILO BUTRATE</td><td>Geranyl butyrate</td>
<td> 68133-79-9</td><td>Squeeze</td><td>Geranyl cydopentanone</td>
<td> 105-86-2</td><td>GERANILO FORMAT</td><td>Geranyl formate</td>
<td> 5146-66-7</td><td>CITRALVA PLUS</td><td>Geranyl nitrile</td>
<td> 102-22-7</td><td>GERANYL PHENYLACETATE</td><td>Geranyl phenylacetate</td>
<td> 57934-97-1</td><td>GIVESCONE</td><td>Givescone</td>
<td> 68901-32-6</td><td>GLYCOLIERRAL</td><td>Glycolierral</td>
<td> 68611-23-4</td><td>GRISALVA</td><td>Grisalva</td>
<td> 24237-00-1</td><td>GYRANE</td><td>Gyrane</td>
<td> 34902-57-3</td><td>100% HABANOLIDE</td><td>Habanolide</td>
<td> 120-57-0</td><td>HELIOTROPINE</td><td>Heliotropin</td>
<td> 40527-42-2</td><td>DIETHYL ACETAL HELIOTROPIN</td><td>Diethyl heliotropin acetal</td>
<td> 141773-73-1</td><td>HELVETOLIDE 947650</td><td>Helvetolide</td>
<td> 25304-14-7</td><td>HERBAC</td><td>Herbac</td>
<td> 116044-44-1</td><td>HERBANATE</td><td>Herbanate</td>
<td> 54546-26-8</td><td>HERBOXANE</td><td>Herboxan</td>
<td> 109-29-5</td><td>SILVANONE Cl</td><td>Hexadecanolide</td>
<td> 3681-73-0</td><td>HEXAROSA 947855</td><td>Hexarose</td>
<td> 10032-15-2</td><td>HEXYL-2-METHYL BUTYRATE</td><td>Hexyl 2-methyl butanoate</td>
<td> 142-92-7</td><td>HEXYL ACETATE</td><td>Hexyl acetate</td>
<td> 2349-07-7</td><td>HEXYL ISOBUTYRATE</td><td>Hexyl isobutyrate</td>
<td> 111-13-7</td><td>METHYL HEXYL KETONE</td><td>Hexyl methyl ketone</td>
<img file="MX337136B_D0032.tif" />
<td> 93-53-8</td><td>HYDRAPHROPIC ALDEHYDE</td><td>Hydrapaldehldo</td>
<td> 122-97-4</td><td>PHENYL PROPOLIC ALCOHOL</td><td>Hydrocinamyl alcohol</td>
<td> 118562-73-5</td><td>HYDROXYAMBRAN</td><td>Hydroxyambran</td>
<td> 107-75-5</td><td>HYDROXICITRONELAL</td><td>Hydroxycitronellal</td>
<td> 107-74-4</td><td>HYDROXYOL</td><td>Hydroxy-citronellol</td>
<td> 120-72-9</td><td>INDOL</td><td>Indole</td>
<td> 28645-51-4</td><td>AMBRETOLID</td><td>Iso ambretolid</td>
<td> 123-92-2</td><td>AMYL- ACETATE (MIXTURES OF ISOMERS)</td><td>Amyl isoacetate</td>
<td> 58683-20-5</td><td>ISOBERGAMATE</td><td>Isobergamate</td>
<td> 125-12-2</td><td>ISOBORNIL ACETATE</td><td>Isobornyl acetate</td>
<td> 66072-32-0</td><td>ISOBORNIL CYCLOHEXANOL</td><td>Isobornyl cyclohexanol</td>
<td> 2756-56-1</td><td>ISOBORNIL PROPIONATE</td><td>Isobornyl propionate</td>
<td> 110-19-0</td><td>NATURAL ISOBUTYL ACETATE</td><td>Isobutyl acetate</td>
<td> 105-79-3</td><td>ISOBUTYL CAPROATE</td><td>Isobutyl caproate</td>
<td> 102-13-6</td><td>ISOBUTYL PHENYLACETATE</td><td>Isobutyl phenylacetate</td>
<td> 87-19-4</td><td>ISOBUTIL SALICILATO</td><td>Isobutyl salicylate</td>
<td> 1335-66-6</td><td>ISO CYCLE CITRAL</td><td>Isocyclocitral</td>
<td> 68527-77-5</td><td>ISOCICLOGERANIOL</td><td>Isocyclogeraniol</td>
<td> 39872-57-6</td><td>ISODAMASCONA N 3/055152</td><td>Isodamascone</td>
<td> 54464-57-2</td><td>ISO CYCLEMONE E</td><td>Iso-E Super</td>
<td> 97-54-1</td><td>ISOEUGENOL</td><td>Isoeugenol</td>
<td> 93-29-8</td><td>ISOEUGENOLACETATE</td><td>Isoeugenil acetate</td>
<td> 120-11-6</td><td>BENCIL ISOEUGENOL</td><td>Isoeugenil benzyl ether</td>
<td> 37677-14-8</td><td>ISO HEXENIL CYCLOHEXENIL CARBOXALDEHlDO</td><td>Isohexenyl cyclohexenyl carboxaldehyde</td>
<td> 95-41-0</td><td>ISO JASMONA</td><td>Iso jasmona</td>
<td> 491-07-6</td><td>ISOMENTONA</td><td>Isomentonic</td>
<td> 123-51-3</td><td>ISOAMLLIC ALCOHOL, 98+%</td><td>Isopentanol</td>
<td> 106-27-4</td><td>AMYL BUTRATE</td><td>Isopentyl butyrate;</td>
<td> 66576-71-4</td><td>ISOPROPIL2-METHYL BUTYRATE</td><td>Isopropyl 2-methylbutyrate</td>
<td> 110-27-0</td><td>GALAXOLIDE 50 IPM</td><td>Isopropyl myristate</td>
<td> 89-79-2</td><td>ISOPULEGOL</td><td>Isopulegoi</td>
<td> 18871-14-2</td><td>DIASMOL</td><td>Jasmal</td>
<td> 208041-98-9</td><td>JASMONITRILE 952906</td><td>jasmonitrile</td>
<td> 198404-98-7</td><td>JAVANOL (CONF.-GIV)</td><td>Javanol</td>
<td> 36306-87-3</td><td>LRG 182</td><td>Kefalis</td>
<td> 75490-39-0</td><td>KHUSINIL</td><td>Khusinil</td>
<td> 86115-11-9</td><td>KOAVONE</td><td>Koavone</td>
<td> 92015-65-1</td><td>KOUMALACTONE 953320</td><td>Koumalactone</td>
1, I
I-. ··: ····
OF !.
<img file="MX337136B_D0033.tif" />
<td> 112-54-9</td><td>LAURIC ALDEHYDE</td><td>Lauraldehyde</td>
<td> 2437-25-4</td><td>ALDINYLE 3881 (CONF.-SYN)</td><td>Lauronitrile</td>
<td> 6485-40-1</td><td>CARVONA LEVO</td><td>L-carvona</td>
<td> 67633-96-9</td><td>LIFFAROME</td><td>Liffarome</td>
<td> 80-54-6</td><td>PTBUCINAL</td><td>Lilial</td>
<td> 7392-19-0</td><td>LRG 188</td><td>Limethol</td>
<td> 61792-11-8</td><td>LEMONILO</td><td>Lemonilo</td>
<td> 78-70-6</td><td>LINALOL</td><td>Linalol</td>
<td> 115-95-7</td><td>LINALYL ACETATE</td><td>Linalyl acetate</td>
<td> 126-64-7</td><td>LINALYL BENZOATE</td><td>Linalyl benzoate</td>
<td> 115-99-1</td><td>LINALYL FORMAT</td><td>Linalyl format</td>
<td> 115-99-1</td><td>LINALYL FORMAT</td><td>Linalyl format</td>
<td> 78-35-3</td><td>LINALYL ISOBUTYRATE</td><td>Linalyl isobutyrate</td>
<td> 144-39-8</td><td>LINALYL PROPIONATE</td><td>Linalyl propionate</td>
<td> 31906-04-4</td><td>LIRAL</td><td>Liral</td>
<td> 67845-30-1</td><td>MACEAL</td><td>Maceal</td>
<td> 103694-68-4</td><td>MAJANTOL</td><td>Majantol</td>
<td> 118-71-8</td><td>MALTOL</td><td>Maltoi</td>
<td> 134769-33-8</td><td>MANDARIL 600 135</td><td>Mandarin</td>
<td> 13828-37-0</td><td>MAYOL</td><td>Mayol</td>
<td> 106-72-9</td><td>MELONAL</td><td>Melonal</td>
<td> 30772-79-3</td><td>FORMILTRICICLODECANO</td><td>Melozone</td>
<td> 89-80-5</td><td>RACEMIC CHIN</td><td>Chin</td>
<td> 3613-30-7</td><td>METALOXICITRONAL, PQ</td><td>Metoxicitronelal</td>
<td> 62439-41-2</td><td>MELONAL METOXI</td><td>Melonal methoxy</td>
<td> 111-80-8</td><td>METHYL OCTIN CARBONATE</td><td>Methyl 2-noninoate</td>
<td> 111-12-6</td><td>METHYL HEPTINE CARBONATE</td><td>Methyl 2-octinoate</td>
<td> 28043-10-9</td><td>METHYL CYCLOGERANATE</td><td>Methyl a-cyclogeranate</td>
<td> 134-20-3</td><td>METHYLLANTRANYLATE</td><td>Methylanthranilate</td>
<td> 91-51-0</td><td>PT BUCINAL METHYL ANTRANYLATE</td><td>Methyl anthranilate / lilial Schiff base /</td>
<td> 93-58-3</td><td>METHYL BENZOATE</td><td>Methyl benzoate</td>
<td> 93-08-3</td><td>METHYL BETA-NAPHTILCETONE</td><td>Methyl beta-naphthyl ketone</td>
<td> 103-26-4</td><td>METHYL CINAMATE</td><td>Methyl cinnamate</td>
<td> 24851-98-7</td><td>HEDIONE HC</td><td>Methyldihydrojasmonate</td>
<td> 93-15-2</td><td>METHYLEUGENOL</td><td>Methyleugenol</td>
<td> 93-16-3</td><td>METHYL ISOEUGENOL</td><td>Methyl isoeugenol</td>
<td> 67633-95-8</td><td>METHYL-LAVENDER-KETONE</td><td>Methyl lavender ketone</td>
<img file="MX337136B_D0034.tif" />
<td> 68141-17-3</td><td>METHYLONYLACETALDEHYDE DIMETHYL ACETAL</td><td>Methylnonyl acetaldehyde dimethyl acetal</td>
<td> 112-12-9</td><td>METHYLONYL KETONE</td><td>Methylnonyl ketone</td>
<td> 39212-23-2</td><td>METHYL OCTALACTONE</td><td>Methyl octalactone</td>
<td> 19009-56-4</td><td>METHYL OCTIL ACETALDEHlDO</td><td>Methyl octyl acetaldehyde</td>
<td> 67674-46-8</td><td>PAMPLEMOUSSE METHYL</td><td>Pamplemousse methyl</td>
<td> 110-43-0</td><td>METHYL AMYLCETONE</td><td>Methylpentyl ketone</td>
<td> 3558-60-9</td><td>KEONE</td><td>Methyl phenethyl ether</td>
<td> 93-92-5</td><td>METHYLPHENYL CARBINYL ACETATE</td><td>Methylphenylcarbinyl acetate</td>
<td> 101-41-7</td><td>METHYL PHENYLACETATE</td><td>Methyl phenylacetate</td>
<td> 119-36-8</td><td>METHYL SALICYLATE, USP</td><td>Methyl salicylate</td>
<td> 188570-78-7</td><td>MONTAVERDI</td><td>Montaverdi</td>
<td> 18479-54-4</td><td>MMUGUOL</td><td>Muguol</td>
<td> 541-91-3</td><td>LEVO MUSCONA</td><td>Muscona</td>
<td> 1118-39-4</td><td>PSEUDO LINALYL ACETATE</td><td>Myrcenyl acetate</td>
<td> 95962-14-4</td><td>NECTALACTONE DSR 95430109</td><td>Nectaryl</td>
<td> 56973-85-4</td><td>GALBASCONA</td><td>Neobutenone</td>
<td> 111-79-5</td><td>METHYL-2-NONENOATE</td><td>Neofoliona</td>
<td> 106-25-2</td><td>NEROL</td><td>Nerol</td>
<td> 7212-44-4</td><td>NEROLIDOL</td><td>Nerolidol</td>
<td> 93-04-9</td><td>BETA NAFTOL METHYL ETHER</td><td>Nerolin</td>
<td> 23911-56-0</td><td>NEROLIONA 600321</td><td>Neroliona</td>
<td> 141-12-8</td><td>NERYL ACETATE</td><td>Nenium acetate</td>
<td> 66-25-1</td><td>HEXYL ALDEHYDE</td><td>n-Hexanal</td>
<td> 6259-76-3</td><td>HEXYL SALICYLATE</td><td>N-Hexyl Salicylate</td>
<td> 124-19-6</td><td>NONYL ALDEHYDE</td><td>Nonaldehyde</td>
<td> 143-08-8</td><td>NONlLIC ALCOHOL</td><td>Nonyl alcohol</td>
<td> 128-51-8</td><td>NOPILO ACETATE</td><td>Nopilo acetate</td>
<td> 5986-38-9</td><td>OCIMENOL</td><td>Ocimenol</td>
<td> 30168-23-1</td><td>DUPICAL</td><td>Octah¡dro-4,7-methanolndanilldenobutanal</td>
<td> 86803-90-9</td><td>SCENTENAL</td><td>octahydro-5-methoxy, 4,7-methane-1H-yndene- 2-carboxaldehyde</td>
<td> 4430-31-3</td><td>BICLONONALACTONE</td><td>Coumarin octahydro</td>
<td> 103614-86-4</td><td>OCTALINOL (CONF.-FIRM)</td><td>Octalinol</td>
<td> 131812-67-4</td><td>OKOUMAL</td><td>Okoumal</td>
<td> 88-41-5</td><td>2-T-BUTYL CYCLOHEXYL ACETATE</td><td>o-tert-butylcyclohexyl acetate</td>
<td> 1725-01-5</td><td>OXALIDE T</td><td>Oxallde</td>
<td> 28940-11-6</td><td>CALOÑA 1951</td><td>Oxalone</td>
go H / Τ Ό Τ <sup>Jl</sup>
INST-TUT ·: DH L · '
<td> 59323-76-1</td><td>ΟΧΑΝΟ</td><td>Oxano .........................</td>
<td> 22629-49-8</td><td>2-TRIDECEN0NITRIL0</td><td>Ozonil</td>
<td> 123-11-5</td><td>ANALSIC ALDEHYDE</td><td>p-Anisaldehyde</td>
<td> 5471-51-2</td><td>FOR HYDROXY PHENYL BUTANONE</td><td>para-hydroxy phenyl butanone</td>
<td> 142653-61-0</td><td>PARMANYL 3/055119</td><td>Parmanyl</td>
<td> 98-52-2</td><td>PATCHON</td><td>Patchone</td>
<td> 5986-55-0</td><td>HEALINGWOOD</td><td>Patchuli alcohol</td>
<td> 106-44-5</td><td>PARA-CRESOL</td><td>p-Cresol</td>
<td> 103-93-5</td><td>ISOBUTYRATE OF FOR CRESILO</td><td>p-Cresyl isobutyrate</td>
<td> 104-93-8</td><td>FOR CRESYL METHYL ETHER</td><td>P-Cresyl Methyl Ester</td>
<td> 99-87-6</td><td>CYMENO COEUR</td><td>p-Cimeno</td>
<td> 67663-01-8</td><td>PEACHOLIDE 600038</td><td>Peacholide</td>
<td> 39255-32-8</td><td>ETHYL 2 METHYL PENTANOATE</td><td>Pentanoic acid, 2-methyl-, ethyl ester</td>
<td> 10461-98-0</td><td>PEONYL</td><td>Peonyl</td>
<td> 313973-37-4</td><td>PHARAONE 10</td><td>Pharaone</td>
<td> 80858-47-5</td><td>PHENAFLEUR</td><td>Phenafleur</td>
<td> 60-12-8</td><td>PHENYLETHLIC ALCOHOL</td><td>Phenethyl alcohol</td>
<td> 104-62-1</td><td>PHENYL ETHYL FORMAT</td><td>Phenyl ethyl format</td>
<td> 56011-02-0</td><td>PHENYL ETHYL ISOAMYL ETHER (ALSO KNOWN AS ANTHER)</td><td>Phenethyl isoamyl ether</td>
<td> 103-48-0</td><td>PHENILETYL ISOBUTYRATE</td><td>Phenethyl isobutyrate</td>
<td> 102-20-5</td><td>PHENYLEYLPHENYL ACETATE</td><td>Phenethyl phenylacetate</td>
<td> 55066-48-3</td><td>PHENOXANOL</td><td>Phenoxanol</td>
<td> 23495-12-7</td><td>PHENOXYETHYL PROPIONATE</td><td>Phenoxyethyl propionate</td>
<td> 122-78-1</td><td>PHENYL ACETALDEHYDE</td><td>Phenylacetaldehyde</td>
<td> 101-48-4</td><td>PHENYLACETALDEHYDE DIMETILACETAL</td><td>Phenylacetaldehyde dimethyl acetal</td>
<td> 5331-14-6</td><td>CRESSANTHER</td><td>Phenylethyl n-butyl ether</td>
<td> 55418-52-5</td><td>RECYCLED DULCINYL</td><td>Piperonyl acetone</td>
<td> 67662-96-8</td><td>PIVAROSE</td><td>Pivarose Q</td>
<td> 41724-19-0</td><td>PLICATONE</td><td>Pllcatone</td>
<td> 107898-54-4</td><td>NIRVANOL 974650</td><td>Polysanthol</td>
<td> 358331-95-0</td><td>POMAROSE</td><td>Pomarose</td>
<td> 104-45-0</td><td>DHIDROANETOL, FCC-</td><td>p-propyl anisole</td>
<td> 52474-60-9</td><td>PRECYCLEMONE B</td><td>Precyclemone B</td>
<td> 1191-16-8</td><td>PRENIL ACETATE</td><td>Prenyl acetate</td>
<td> 68555-58-8</td><td>PRENILE SALICILATE</td><td>Prenyl salicylate</td>
<td> 98-54-4</td><td>PARA-TER-BUTIL PENOL</td><td>p-tert-butylphenol</td>
<img file="MX337136B_D0035.tif" />
<td> 101-94-0</td><td>FOR CRESIL FENYL ACETATE</td><td>P-toiik phenylacetate ——- =, -</td>
<td> 80-56-8</td><td>ALFA-PINENO</td><td>Racemic alpha-pinene</td>
<td> 141-25-3</td><td>RODINOL 70</td><td>Rodlnol</td>
<td> 82461-14-1</td><td>RHUBAFURAN</td><td>Rhubafuran</td>
<td> 236391-76-7</td><td>ROMANDOLIDE 979031</td><td>Romanolide</td>
<td> 81752-87-6</td><td>ROMASCONE</td><td>Romascone</td>
<td> 25225-10-9</td><td>ROSAMUSK</td><td>Rosamusk</td>
<td> 16409-43-1</td><td>METHYLISOBUTENYLTETRAHYDROPIRAN</td><td>Rose oxide</td>
<td> 215231-33-7</td><td>ROSSITOL</td><td>Rossitol</td>
<td> 65113-99-7</td><td>SANDALORE</td><td>Sandalore</td>
<td> 224031-70-3</td><td>SPIROGALBANONE 10</td><td>Spirogalbanone</td>
<td> 22457-23-4</td><td>STEMONA</td><td>Stemona</td>
<td> 13215-88-8</td><td>TABANON COEUR 659672</td><td>Tabanone</td>
<td> 8000-41-7</td><td>ALPHA-TERPINEOL</td><td>Terpineol</td>
<td> 586-62-9</td><td>TERPINOLENE</td><td>Terplnolene</td>
<td> 5988-91-0</td><td>DIHYDROCITRONELAL</td><td>Tetrahydrogeranial</td>
<td> 13074-63-0</td><td>JASMYLONE</td><td>Tetrahydrojasmona</td>
<td> 78-69-3</td><td>LINACSOL</td><td>Tetrahydrolinalool</td>
<td> 20780-48-7</td><td>TETRAHIDRO LINAIL ACETATO</td><td>Tetrahydrolinalyl acetate</td>
<td> 18479-57-7</td><td>TETRA HIDRO MUGUOL</td><td>Tetrahydromyrcenol</td>
<td> 89-83-8</td><td>TIMOL NF</td><td>Thymol</td>
<td> 3913-81-3</td><td>2 DECAN-1-AL</td><td>Trans-2-decade</td>
<td> 928-95-0</td><td>TRANS-2-HEXENOL</td><td>trans-2-hexenol</td>
<td> 65405-70-1</td><td>DECENNIAL (TRANS-4)</td><td>trans-4-decen-1-al</td>
<td> 4180-23-8</td><td>ANETOL, OF THE PHARMACOPEA OF THE UNITED STATES</td><td>trans-anethole</td>
<td> 106-24-1</td><td>SOMEONE NE</td><td>trans-geraniol</td>
<td> 90-17-5</td><td>ACETATE OF TRICHLOROMETILFENILCARBINILO</td><td>trichloromethylphenylcarbinyl acetate</td>
<td> 2500-83-6</td><td>FLOWER ACETATE</td><td>tricyclodecenyl acetate / Flor acetate</td>
<td> 77-93-0</td><td>GALBANOLENE SUPER 10% IN TEC</td><td>triethyl citrate</td>
<td> 16251-77-7</td><td>TRIFERNAL 989-007</td><td>Trifernal</td>
<td> 112-44-7</td><td>UNDECLLIC ALDEHYDE</td><td>Undecanal</td>
<td> 81782-77-6</td><td>UNDECAVERTOL</td><td>Undecavertol</td>
<td> 121-33-5</td><td>VANILLINE</td><td>Vanillin</td>
<td> 20665-85-4</td><td>ISO BUTAVAN</td><td>Vanillin Isobutyrate</td>
<td> 94-86-0</td><td>VANITROPE</td><td>Vanitrope</td>
<td> 5533-03-9</td><td>VANIWHITE</td><td>Vanlwhite</td>
<img file="MX337136B_D0036.tif" />
<td> 65443-14-3</td><td>VELOUTONE</td><td>Veloutone ........</td><td>............... r · .. · ™ - · * - * ·.</td>
<td> 4707-47-5</td><td>LRG 201</td><td colspan="2">Let's see</td>
<td> 120-14-9</td><td>CORPS 4322</td><td colspan="2">Veratraldehyde</td>
<td> 27135-90-6</td><td>VERDALIAA</td><td colspan="2">Verdalia A</td>
<td> 13491-79-7</td><td>VERDOL</td><td colspan="2">Verdol</td>
<td> 41519-23-7</td><td>VERDURAL B EXTRA</td><td colspan="2">Verdural B Extra</td>
<td> 32388-55-9</td><td>ACETIL CEDRENO</td><td colspan="2">Vertofix</td>
<td> 68738-99-8</td><td>AGRUMEA</td><td colspan="2">Vertoslne</td>
<td> 68083-58-9</td><td>VETICOL ACETATE 3/080515</td><td colspan="2">Veticol acetate</td>
<td> 87731-18-8</td><td>VIOLIFF</td><td colspan="2">Violiff</td>
<td> 133636-82-5</td><td>WOLFWOOD 992393</td><td colspan="2">Wolfwood</td>
<td> 154171-76-3</td><td>YSAMBER K 3/055120</td><td colspan="2">Ysamber</td>
<td> 105-68-0</td><td>PROPIONATED BY AMILO</td><td colspan="2"></td>
<td> 93-99-2</td><td>PHENYLBENZOATE</td><td colspan="2"></td>
<td> 94-47-3</td><td>PHENILETYL BENZOATE</td><td colspan="2"></td>
In one aspect, the flavoring may comprise a flavoring used in oral care type compositions and may comprise menthol (L, D, racemic), anethole and anise oil, eucalyptol and eucalyptus oil, peppermint oil, Cornmint or Peppermint Arvensis, Peppermint Oil, I Carvone, Clove Oil, Cinnamic Aldehyde and Cinnamon Derivatives, Refreshing Agents (also called Sense Perceived Agents, such as those described in the US Patent. no. 2007/0233026 A1), such as aliphatic carboxamides (which include WS-3 available as ISE 3000, from Qaroma, Inc., and WS-23, available as ISE 1000, from Qaroma, Inc.), ketals (which include MGA (available from Symrise)), chlorchloxyl derivatives (including TK10, Coolact, available from LIPO Chemicals of Paterson, NJ) and mono-menthol succinate (available from
<img file="MX337136B_D0037.tif" />
trade name Physcool), sweeteners such as saccharin sodium, sucralose, neohesperidin, eugenol and clove oils, cinnamic aldehyde and cinnamon derivatives, flavored flavoring materials, methyl salicylate and spearmint derivatives, as well as combinations thereof.
In one aspect, the flavor may comprise a flavor "modifier" and may include a fruity or dairy flavor, such as vanillin, ethyl vanillin, sulfur derivatives to achieve notes of dairy and / or exotic fruit, furanone, ethyl esters, damascones, ionones, allyl esters, butyric esters, flower, leaf and wood essential oils, absolutes, plant extracts and combinations thereof.
The raw materials, chords and flavorings of the perfume can be obtained from one or more of the following companies Firmenich (Genoa, Switzerland), Givaudan (Argenteuil, France), IFF (Hazlet, NJ), Quest (Mount Olive, NJ), Bedoukian (Danbury, CT), Sigma Aldrich (St. Louis, MO), Millennium
Specialty Chemicals (Olympia Fields, IL), Polarone International (Jersey City, NJ), Fragrance Resources (Keyport, NJ) and Aroma & Flavor Specialties (Danbury, CT).
Process for making encapsulated beneficial agents
The encapsulated beneficial agents employed herein could be manufactured using the principles of US patents. USA no.
6,592,990 B2 and / or 6,544,926 B1 and the examples described in the present description.
<img file="MX337136B_D0038.tif" />
Anionic emulsifiers are typically used during the encapsulation process to emulsify the beneficial agent prior to microcapsule formation. Without being bound by theory, anionic materials are believed to interact adversely with cationic surfactant assets that are often found in compositions such as fabric care compositions; this can produce an aggregation of aesthetically unpleasant particles that are used in said composition. In addition to unpleasant aesthetics, aggregates can result in rapid phase separation of the particles from the bulk phase. Applicants discovered that aggregates can be prevented by the addition of certain aggregate inhibiting materials, including materials selected from the group consisting of salts, polymers, and mixtures thereof. Aggregation inhibiting materials that are useful include divalent salts, such as magnesium salts, for example, magnesium chloride, magnesium acetate, magnesium phosphate, magnesium format, magnesium boride, magnesium titanate, magnesium sulfate heptahydrate; calcium salts, for example, calcium chloride, calcium format, calcium acetate, calcium bromide; trivalent salts, such as aluminum salts, for example, aluminum sulfate, aluminum phosphate, aluminum chloride n-hydrate, and polymers that have the ability to suspend anionic particles, such as polymers for soil suspension, for example , polyethyleneimines, polyethyleneimines alkoxylate, polyquaternium-6 and polyquaternium-7.
<img file="MX337136B_D0039.tif" />
In one aspect of the invention, encapsulated beneficial agents are manufactured and subsequently coated with a material to reduce the rate of dropping of the beneficial agent from the particles when the particles are subjected to a bulk environment containing, for example , surfactants, polymers and solvents. Non-limiting examples of coating materials that can serve as barrier materials include materials selected from the group consisting of polyvinyl pyrrolidone homopolymer and its various copolymers with styrene, vinyl acetate, imidazole, primary and secondary amine containing monomers, methylacrylate , polyvinyl acetal, maleic anhydride; polyvinyl alcohol homopolymer and its various copolymers with vinyl acetate, 2-acrylamide 2-methylpropane sulfonate, primary and secondary amines containing monomers, imidazoles, methylacrylates; polyacrylamides; polyacrylic acids; microcrystalline waxes; paraffin waxes; modified polysaccharides such as waxy corn or corn starch, octenyl succinate starches, derivatized starches such as hydroxyethylated or hydroxypropyl starches, carrageenan, guar gum, pectin, xanthan gum; modified celluloses such as hydrolyzed cellulose acetate, hydroxy propyl cellulose, methyl cellulose and the like; modified proteins such as gelatin; hydrogenated and non-hydrogenated polyalkines; fatty acids; hardened coatings, such as formaldehyde crosslinked urea, gelatin-polyphosphate, melamine formaldehyde, tetraborate crosslinked polyvinyl alcohol or sodium gluteraldehyde; styrene-butadiene latex, ethyl cellulose, inorganic materials such
I Κ'Τ Ό i
<img file="MX337136B_D0040.tif" />
as clays including magnesium silicates, aiuminosilicates; sodium silicates and the like and mixtures thereof. Such materials can be obtained from CP Kelco Corp. of San Diego, California, USA. UU .; Degussa AG or Dusseldorf, Germany; BASF AG from Ludwigshafen, Germany; Rhodia Corp. of Cranbury, New Jersey, USA. UU .; Baker Hughes Corp. of Houston, Texas, USA. UU .; Hercules Corp. of Wilmington, Delaware, USA. UU .; Agrium Inc. of Calgary, Alberta, Canada, ISP of New Jersey, USA. USA
Suitable equipment for use in the processes described in this description may include continuous agitation tank reactors, homogenizers, turbine agitators, recirculating pumps, vane mixers, grate mixers, horizontal helical ribbon mixer, vertical shaft granulators, and drum mixers, both batch and, if available, in continuous process configurations, spray dryers and extruders. Such equipment can be obtained from Lodige GmbH (Paderborn, Germany), Littleford Day, Inc. (Florence, Kentucky, USA), Forberg AS (Larvik, Norway), Glatt Ingenieurtechnik GmbH (Weimar, Germany), Niro (Soeborg , Denmark), Hosokawa Bepex Corp. (Minneapolis, Minnesota, USA), Arde Barinco (New Jersey, USA).
Formaldehyde scrubbers
In one aspect, the encapsulated beneficial agent could be combined with a formaldehyde scavenger. In one aspect, the encapsulated beneficial agent could comprise the encapsulated beneficial agent of
<img file="MX337136B_D0041.tif" />
the present invention. Suitable formaldehyde scavengers include materials selected from the group consisting of sodium bisulfite, urea, ethylene urea, cysteine, cysteamine, lysine, glycine, serine, carnosine, histidine, glutathione, 3,4-diaminobenzoic acid, allantoin, glyceryl, acid anthranilic, methylanthranilate, methyl 4-aminobenzoate, ethyl acetoacetate, acetoacetamide, malonamide, ascorbic acid, 1,3-dihydroxyacetone dimer, biuret, oxamide, benzoguanamine, pyroglutamic acid, pyrogaloi, methyl gaiate, ethyl gallate, propyl gallate, triethanolamine, succinamide, thiabendazole, benzotriazole, triazole, indoline, sulphanilic acid, oxamide, sorbitol, glucose, cellulose, partially hydrolyzed poly (vinylformamide), poly (vinyl amine) , poly (ethylene amine), poly (oxyalkylene) amine, poly (vinyl alcohol) -co-poly (vinyl amine), poly (4-aminostirene), poly (l-lysine), chitosan, hexanediol, ethylenediamine-N. N'-bisacetoacetamide, N- (2-ethylhexyl) acetoacetamide, 2benzoylacetoacetamide, N- (3-phenylpropyl) acetoacetamide, lilial, helional, melonal, triplal, 5,5-dimethyl-1,3-cyclohexanedione, 2,4-dimethyl-3-cyclohexenecarboxaldehyde, 2,2-dimethyl-1,3-dioxan -4,6-dione, 2-pentanone, dibutyl amine, triethylenetetramine, ammonium hydroxide, benzyl amine, hydroxycitronellol, cyclohexanone, 2-butanone, pentane dion, dehydroacetic acid, or a mixture of these. These formaldehyde scrubbers could be obtained from Sigma / Aldrich /, of St. Louis, MO. USA UU, or PolySciences, Inc. of Warrington, PA, EE. USA
Formaldehyde scrubbers are typically combined with a grout containing the agent-containing supply particle
<img file="MX337136B_D0042.tif" />
beneficial, on one level, based on total grout weight, from about 2% by weight to about 18% by weight, from about 3.5% by weight to about 14% by weight, or even from about 5% by weight at about 13% by weight.
In one aspect, such formaldehyde scavengers can be combined with a product containing a supply particulate-containing beneficial agent, such scavengers are combined with said product at a level, based on the total weight of the product, of about 0.005% to about 0.8%, alternatively, about
0.03% to about 0.5%, alternatively, from about
0.065% to approximately 0.25% of the product formulation.
In another aspect, such formaldehyde scavengers could be combined with an aqueous compound containing the beneficial agent encapsulated at one level, based on the total weight of the aqueous compound, from about 2% by weight to about 14% by weight, from about 3.5 % by weight to about 14% by weight, or even from about 5% by weight to about 14% by weight, and the aqueous compound can be added to a product matrix to which an identical or different scrubber can be added at one level, based on the total weight of the product, from about 0.005% to about
0.5%, alternatively, from about 0.01% to about
0.25%, alternatively, from about 0.05% to about
0.15% of the product formulation.
<img file="MX337136B_D0043.tif" />
In one aspect, one or more of the aforementioned formaldehyde scrubbers could be combined with a consumer product containing a beneficial agent encapsulated at one level, based on the total weight of the fabric-enhancing liquid product, from 0.005% to about 0.8 %, alternatively from about 0.03% to about 0.4%, alternatively, from about 0.06% to about 0.25% of the product formulation.
In one aspect, formaldehyde scrubbers could be combined with a liquid laundry detergent product containing a benefit agent that contains the supply particle, such scrubbers are selected from the group consisting of sodium bisulfite, ureas, ethylene urea, cysteine, cysteamine, lysine, glycine, serine, carnosine, histidine, glutathione, 3,4-diaminobenzoic acid, allantoin, glyceryl, anthranilic acid, methyl anthranilate, methyl 4-aminobenzoate, ethyl acetoacetate, acetoacetamide, malonamide, ascorbic acid, 1,3-dihydroxyacetone dimer, biuret, oxamide, benzoguanamine, pyroglutamic acid, pyrogalol, methyl gallate, ethyl gallate, propyl gallate, triethanolamine, succinamide, thiabzol, indoline, sulphanilic acid, oxamide, sorbitol, glucose, cellulose, poly (vinyl alcohol), partially hydrolyzed poly (vinylformamide), poly (vinyl amine), poly (ethyleneimine), poly (oxyalkyleneamine), poly (vinyl alcohol) -co-poly (vinyl amine), poly (4-aminostyrene), poly (l-lysine), chitosan, hexane diol, ethylenediamine-N, N'-bisacetoa ceta mida, N- (2-ethylhexyl) acetoacetamide, 2-benzoylacetoacetamide,
<img file="MX337136B_D0044.tif" />
N- (3-phenylpropyl) acetoacetamide, lilial, helional, melonal, tripjjal ,, 5,5-dimethyl-1,3cyclohexanedione, 2,4-dimethyl-3-cyclohexenecarboxaldehyde, 2,2-dimethyl-1,3-dioxan-4, 6-dione, 2-pentanone, dibutyl amine, triethylenetetramine, ammonium hydroxide, benzylamine, hydroxycitronellol, cyclohexanone, 2-butanone, pentanedione, dehydroacetic acid, and mixtures thereof, and combined with the mentioned liquid laundry detergent product at one level , based on the total weight of the liquid laundry detergent product, from about 0.003% by weight to about 0.20% by weight or from about 0.03% by weight to about 0.20% by weight or from about 0.06% by weight to about 0.14% in weight.
In one aspect, formaldehyde scrubbers can be combined with a hair conditioning product containing a delivery particle containing beneficial agents, at one level, based on the total weight of the hair conditioning product, of about 0.003% by weight to about 0.30% by weight, from about 0.03% by weight to about 0.20% by weight, or from about 0.06% by weight to about 0.14% by weight; the selection of scrubbers is identical to the list of scrubbers in the previous paragraph regarding a liquid laundry detergent product.
<img file="MX337136B_D0045.tif" />
Compositions comprising delivery particles containing beneficial agents
Applicant's consumer products could comprise one embodiment of the beneficial agent delivery composition described in the present application. In one aspect, consumer products could be a powdered, granular, or other essentially dry detergent.
In one aspect, a consumer product is disclosed that could comprise one or more beneficial agent delivery compositions of the present invention and an additional ingredient.
In one aspect of the aforementioned consumer product, the additional consumer product agent could be selected from the group consisting of polymers, for example, cationic polymers, surfactants, additives, chelating agents, dye transfer inhibiting agents, dispersants, enzymes and enzyme stabilizers, catalytic materials, bleach activators, polymeric dispersing agents, clay soil removal / anti-redeposition agents, brighteners, foam suppressants, colorants, other perfumes and perfume delivery systems, framework elasticizing agents, fabric softeners, carriers, hydrotropes, process aids and / or pigments and mixtures thereof.
In one aspect of the consumer product mentioned above, the consumer product could comprise a total of, based on the total weight of the consumer product, of about 0.1% a; 1 IO. , 'f A i<sup>Ií;</sup>'peels -? <? λ '<sup>[</sup>A: ri_Ar ~ Á approximately 20%, approximately 0.2% ^ approximately 15%, approximately 0.3% to approximately 10%, approximately 0.4% to approximately 8% or even approximately 0.5% to approximately 5% of one or more of the beneficial agent delivery compositions of the present invention.
In one aspect of the aforementioned consumer product, the consumer product may comprise one or more of the beneficial agent delivery compositions of the present invention and a material selected from the group consisting of colorants; fragrance; optical brighteners; deposition aids and mixtures thereof.
Beneficial agent delivery compositions can be used in laundry detergent compositions (eg, TIDE ™), hard surface cleaners (eg, MR CLEAN ™), automatic dishwashing liquids (eg. eg CASCADE ™) and floor cleaners (eg
SWIFFER ™). Non-limiting examples of cleaning compositions can include those described in US Pat. USA nos. 4,515,705; 4,537,706; 4,537,707; 4,550,862; 4,561,998; 4,597,898; 4,968,451; 5,565,145; 5,929,022; 6,294,514 and 6,376,445. The cleaning compositions described herein are typically formulated such that, during use in aqueous cleaning operations, the wash water will have a pH of from about 6.5 to about 12, or from about 7.5 to
10.5. Liquid dishwashing formulations typically have a pH of about 6.8 to about 9.0.
<img file="MX337136B_D0046.tif" />
Cleaning products are typically formulated to have a pH of about 7 to about 12. pH control techniques at recommended usage levels, include the use of buffers, alkalis, acids, etc. and are known to those with industry experience.
Additional materials
Although not essential, the non-limiting list of additional ingredients illustrated hereinafter are suitable for use in the present compositions and may be conveniently incorporated in certain aspects of the invention, for example, to assist or improve performance, for the treatment of the substrate to be cleaned or to modify the aesthetics of the composition, as in the case of perfumes, dyes, dyes or the like. Auxiliaries are understood to be in addition to components supplied via applicant's agglomerates / particles. The precise nature of these additional components and the levels of incorporation of these will depend on the physical form of the composition and the nature of the operation for which they will be used. Suitable auxiliary materials include, but are not limited to, polymers, eg, cationic polymers, surfactants, additives, chelating agents, dye transfer inhibitors, dispersants, enzymes and enzyme stabilizers, catalytic materials, bleach activators , polymeric dispersing agents, clay soil removal / anti-redeposition agents, polishes, suppressants
<img file="MX337136B_D0047.tif" />
IU:
Foam, colorants, additional perfumes and supply systems for ----------- perfumes, elasticizing agents for the structure, fabric softeners, carriers, hydrotropes, processing aids and / or pigments. In addition to the following description, suitable examples of such additional ingredients and levels of use are found in US Pat. USA nos. 5,576,282, 6,306,812 B1 and 6,326,348 B1.
As stated, the auxiliary ingredients are not essential for applicants' cleaning and fabric care compositions. Therefore, certain embodiments of applicants' compositions do not contain one or more of the following additional materials: bleach activators, surfactants, additives, chelating agents, dye transfer inhibiting agents, dispersants, enzymes and enzyme stabilizers, catalytic metal complexes, polymeric dispersing agents, clay and dirt removal agents / anti-redeposition agents, brighteners, Foam suppressants, dyes, perfumes and additional perfume delivery systems, structure elasticizing agents, fabric softeners, carriers, hydrotropes, processing aids and / or pigments. However, when one or more of the additional materials are present, these additional materials may be present as detailed below:
Surfactants. Compositions in accordance with the present invention may comprise a surfactant or surfactant system, wherein the surfactant can be selected from
<img file="MX337136B_D0048.tif" />
nonionic and / or anionic and / or cationic surfactants, and / or ampholytic and / or amphoteric and / or semipolar nonionic surfactants. Typically, the surfactant is present in a concentration of about 0.1%, about 1%, or even about 5%, by weight of the cleaning compositions, at about 99.9%, at about 80%, at about 35%, or even at about 30%, by weight of the cleaning compositions.
Additives. The compositions of the present invention may comprise one or more detergent additives or additive systems. When present, the compositions will typically comprise at least about 1% additive, or from about 5% or 10% to about 80%, 50%, or even 30% by weight, of the additive. Additives include, but are not limited to, the alkali metals, ammonium and acanolammonium salts of polyphosphates, alkali metal silicates, alkaline earths and alkali metal carbonates, aluminosilicate structurants, polycarboxylate compounds, hydroxypolycarboxylate ether, maleic anhydride copolymers with ethylene or vinyl methyl ether, 1,3,5-tr-hydroxybenzene-2,4,6-trisulfonic acid, and carboxymethyl-oxysuccinic acid, the various alkali metals, ammonium and substituted ammonium salts of polyacetic acids, such as tetraacetic acid, ethylenediamine and nitrilotriacetic acid, as well as polycarboxylates, such as melific acid, succinic acid, oxydisuccinic acid, polymaleic acid, benzene 1,3,5-tricarboxylic acid, carboxymethyloxysuccinic acid, and soluble salts of these.
<img file="MX337136B_D0049.tif" />
Chelating agents. The compositions in the ^ jiesenteinvention
- * - · i. J »'T - may also optionally contain one or more chelating agents of copper, iron and / or manganese. If used, chelating agents will generally comprise from about 0.1% by weight of the compositions in the present invention to about 15%, or even from about 3.0% to about 15%, by weight of the compositions, in the present invention .
Dye transfer inhibiting agents. The compositions of the present invention may further include one or more dye transfer inhibiting agents. Dye transfer inhibiting agents that are suitable include, but are not limited to, polyvinylpyrrolidone polymers, N-oxide polyamine polymers, Nvinylpyrrolidone and N-vinylimidazole copolymers, polyvinyloxazolidones, and polyvinylimidazoles or mixtures thereof. When present in the compositions in the present invention, dye transfer inhibiting agents are present in concentrations of from about 0.0001%, to about 0.01%, from about 0.05%, by weight of the cleaning compositions, to about 10%, about 2% or even about 1%, by weight of the cleaning compositions.
Dispersants. The compositions of the present invention may additionally contain dispersants. Suitable water soluble organic materials are homo or copolymeric acids or their salts, in which
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<img file="MX337136B_D0050.tif" />
¡Ia® ..........,
INSTITUTE b, \ '; 5; N2 LA PL '<sub>t</sub>-which the polycarboxylic acid can comprise at least two carboxyl radicals separated from each other by not more than two atoms of '
Enzymes. The cleaning compositions may comprise one or more enzymes beneficial for cleaning performance and / or fabric care. Examples of suitable enzymes include, but are not limited to, hemicellulases, cellulases, cellobiose dehydrogenases, peroxidases, proteases, xylanases, lipases, phospholipases, esterases, cutinases, pectinases, mannases, pectates liases, keratinases, oxidases, phenases, , ligninases, pullulanases, tanases, pentosanases, malanases, β-glucanases, arabinosidases, hyaluronidase, chondroitinase, laccase and amylases or mixtures of these. A typical combination is an enzyme mixture comprising, for example, a protease and lipase together with amylase. When present in a cleaning composition, the concentration of the aforementioned additional enzymes may be within the ranges of from about 0.00001% to about 2%, from about 0.0001% to about 1%, or from about 0.001% to about 0.5% enzyme protein by weight of the composition.
Suitable enzymes are commercially available from Genencor International Inc., Palo Alto, California, AB.
Enzymes GmbH, Darmstadt, Germany and Novozymes A / S, Bagsvaerd,
Denmark and include Alcalase®, Savinase®, Primase®, Durazym®,
Polarzyme®, Kannase®, Liquanase®, Ovozyme®, Neutrase®, Everlase®,
Esperase®, Maxatase®, Maxacal®, Maxapem®, Properase®, Purafect®,
Purafect Prime®, Purafect Ox®, FN3®, FN4®, Excellase® and Purafect OXP®,
<img file="MX337136B_D0051.tif" />
DURAMYL®, LIQUEZYME® TERMAMYL®, TERMAMYL ULTRA®,
NATALASE®, SUPRAMYL®, STAINZYME®, STAINZYME PLUS®,
STAINZYME ULTRA®, FUNGAMYL®, BAN® Lipolase®, Lipolase Ultra®, Lipoprime®, Lipex®, Mannaway®, Pectaway®, Pectawash®, Purabrite®, Celluclean®, Carezyme®, Celluzyme®, Biotouch®, Endolase® and Puradase
HA®.
Enzyme stabilizers. Enzymes for use in compositions, for example, detergents, can be stabilized by various techniques. The enzymes used in the present invention can be stabilized by the presence of water soluble sources of calcium and / or magnesium ions in the final compositions that supply the ions to the enzymes.
Catalytic metal complexes. Applicants' compositions can include catalytic metal complexes. One type of metal-containing bleaching catalyst is a catalyst system comprising a transition metal cation of defined bleaching catalyst activity, such as copper, iron, titanium, ruthenium, tungsten, molybdenum or manganese cations, an auxiliary metal cation having little or no bleaching catalyst activity, such as zinc or aluminum cations, and a part having defined stability constants for catalytic and auxiliary metal cations, particularly ethylenediaminetetracetic acid,
IMPI
MEXICAN INSTITUTE ethylenediaminotetra (methylenophosphonic acid) and soluble salts in
<img file="MX337136B_D0052.tif" />
These catalysts are described in US Pat. USA núrru- 4,430,243.
If desired, the compositions herein can be catalyzed by means of a manganese compound. These compounds and usage levels are well known in the industry and include, for example, the manganese-based catalysts described in US Pat. USA
no. 5,576,282.
The cobalt bleaching catalysts useful in the present invention are known and described, for example, in US Pat. USA nos. 5,597,936 and 5,595,967. These cobalt catalysts are easily prepared by known procedures, such as those described in US Pat. USA nos. 5,597,936 and 5,595,967.
The compositions of the present invention may further conveniently include a transition metal complex of a macropolycyclic rigid ligand (abbreviated as MRL). For a practical and not limiting matter, the cleaning compositions and processes of the present invention can be regulated to provide on the order of at least one part per hundred million of the MRL species of the beneficial agent in the aqueous washing medium, and they can provide from about 0.005 ppm to about 25 ppm, from about 0.05 ppm to about 10 ppm, or even
Μ> τ ιν;
r; ·; s α ···· ·. '-r ··. · \ ·.
approximately 0.1 ppm to approximately 5 ppm of the MRL in the wash liquor.
Preferred transition metals in the transition metal bleaching catalyst of the present invention include manganese, iron, and chromium. Preferred MRLs in the present invention are a special type of ultra-rigid ligand that is a bridge, such as 5,12diethyl-1,5,8,12-tetraazabicyclo [6.6.2] hexadecane.
Suitable transition metal MRLs are readily prepared by known procedures, as described, for example, in WO 00/32601 and in US Pat. USA no. 6,225,464.
Processes for manufacturing and using compositions
The compositions of the present invention can be formulated in any form and prepared by any process chosen by the formulator, the non-limiting examples of which are described in US patents. USA nos. 5,879,584; 5,691,297; 5,574,005; 5,569,645; 5,565,422; 5,516,448; 5,489,392; 5,486,303.
Method of use
<img file="MX337136B_D0053.tif" />
The compositions containing the encapsulated beneficial agent described herein can be used to clean or treat a site, inter alia, a surface or cloth. Typically at least a portion of the
<img file="MX337136B_D0054.tif" />
The site is contacted with an embodiment of the applicants' composition, pure or diluted in a liquid, for example, a washing liquid, and then optionally the site can be washed and / or rinsed. In one aspect, a site can optionally be washed and / or rinsed in contact with one or more beneficial agent delivery compositions of the present invention or a consumer product comprising one or more beneficial agent delivery compositions of the present invention. present invention and then optionally washed and / or rinsed. For the purposes of the present invention, washing includes, but is not limited to, scrubbing, and mechanical agitation. The fabric can comprise almost any fabric that can usually be washed or treated under normal conditions of use for consumption. Liquors that can comprise the described compositions can have a pH d from about 3 to about 11.5. The compositions are typically employed in concentrations of from about 500 ppm to about 15,000 ppm in solution. When the wash solvent is water, the temperature typically ranges from about 5 ° C to about 90 ° C and, when the site comprises a fabric, the water to fabric ratio is typically from about 1: 1 to about 30: 1.
Test methods
It is understood that the test methods set forth in the Test Methods section of the present application are those that should be used to determine the respective values of the applicant's invention parameters, as described and claimed by the invention in the present description.
<img file="MX337136B_D0055.tif" />
<img file="MX337136B_D0056.tif" />
Method to determine the characteristic dimension (agglomerates and particles)
The particle size distribution of the beneficial agent delivery composition is determined using the ASTM test method E726-01 "Particle Size Distribution of Granular Carrlers and Granular Pesticides". Specifically, the method must be carried out using a Tyler RoTap sieve shaker supplied with a centrally mounted cork cast iron sieve basin lid (WS Tyler Company, Cleveland, Ohio). At least 5 sieve sizes should be selected to cover the full range of particle sizes of the material being analyzed (step 7.1). If more than 40% by weight of the sample is found on a single screen after screening, then the screen selection should be changed and the sample should be retested until <40% by weight is found on all screens.
The following parameters for RoTap operation should be applied to step 7.4 of the method:
1) 152 vibrations / minute
2) 285 rpm of elliptical motion
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INSTI
3) 5 mm protrusion of the cork on the lid, from the top of the beaker, j
4) A 33mm hammer drop from the peak height to the top of the cork.
5) Sieving time: 5 minutes.
The data is plotted on a semi-log graph in which the opening of each screen is plotted in microns against the logarithmic abscissa and percent cumulative mass (Q3) plotted against the linear ordinate. An example of the above data representation is provided in ISO 9276-1: 1998, "Representation of Particle Size Analysis Results - Part 1: Graphical Representation", Figure A.4. For the purposes of this invention, the mean seed particle size (D50) is defined as the abscissa value at the point at which the cumulative mass percentage equals 50 percent and is calculated by an interpolation of straight line between data points directly above (a50) and below (b50) the value of 50% using the following equation:
D50 = 10<sup>TO</sup>[Log (Da50) - (Log (Da50) - Log (Db50)) * (Qa50 - 50%) / (Qa50 Qb50)] where Qa50 and Qb50 are the cumulative mass percentile values of the data immediately above and below the 50th percentile, respectively; and Da50 and Db50 are the sieve size values in microns
<img file="MX337136B_D0057.tif" />
which corresponds to these data. The average particle size on a basis
-<sub>Item</sub>r<sub>(</sub> imn f. I ,,,,,,<sub>r</sub> ,, I,<sub>wti¡ft</sub>- · ^^ of mass is considered, for the purposes of the present application, to have the characteristic dimension.
Method to determine the characteristic dimension (extruded product)
The diameter of an extruded product is obtained by measurement with a micrometer, when the material is at 20 ° C. In order to determine the medium, five representative extruded products are taken from the sample to be tested and measured, taking care not to deform the extruded products during the measurement process, and then the arithmetic mean of those measurements is calculated. The arithmetic medium is considered, for the purposes of the present application, the characteristic dimension of the extruded products.
Examples
Although particular embodiments of the present invention have been illustrated and described, it will be apparent to persons with experience in the industry that various changes and modifications can be made without departing from the spirit and scope of the invention. Therefore, it has been intended to encompass in the appended claims all changes and modifications that are within the scope of this invention.
Example 1 Melamine Based Polyurea Capsule (80% Core / 20% Wall Weight)
A first blend is prepared, combining 208 grams of water and 5 grams of acrylic acid-alkyl acrylate copolymer (Polysciences,
Inc. of Warrington, Pennsylvania, USA. UU). This first mixture is adjusted to pH 5.0 using acetic acid. 125 grams of the capsule core material comprising a scented oil, at a temperature of 45 ° C, are added to the first mixture to form an emulsion. The capsule wall is formed as follows: 9 grams of a copolymer prepolymer (butylacrylate-acrylic acid copolymer) corresponding to the capsule wall material and 90 grams of water are combined and adjusted to a pH of 5.0. 28 grams of a partially methylated methylol melamine resin solution ("Cymel 385", 80% solids, Cytec) are added. This mixture is added to the above-described fragrance oil-in-water emulsion with stirring, at a temperature of 45 ° C. High speed mixing is used to achieve a mean particle size volume of 15 mlcrometers. The temperature of the mixture gradually rises to 65 ° C and is maintained at this temperature overnight, with permanent agitation to start and complete encapsulation. To form the capsule shell of the acrylic acid-alkylacrylate copolymer, the alkyl group can be selected from ethyl, propyl, butyl, amyl, hexyl, cyclohexyl, 2-ethylhexyl or other alkyl groups having from one to about sixteen carbons, preferably , from one to eight carbons.
'->33
Example 2 Polyurea a capsule containing a melamine-based chelator (80% core / 20% wall weight)
A first blend is prepared, combining 208 grams of water and 5 grams of alkylacrylate-acrylic acid copolymer (Polysciences, Inc. of Warrington, Pennsylvania, USA). This first mixture is adjusted to pH 5.0 using acetic acid. In a separate container, 5 mg of ethylenediaminetetracetic acid (EDTA) are added to a 125 gram mixture of the capsule core material comprising a fragrance oil, and mixed for 20 minutes. The second mixture is added to the first mixture at a temperature of 45 ° C, to form an emulsion. The ingredients to form the capsule wall material are prepared as follows: 9 grams of a copolymer prepolymer (butylacrylate-acrylic acid copolymer) corresponding to the capsule wall material and 90 grams of water are combined and adjust to a pH of 5.0. 28 grams of a partially methylated methylol melamine resin solution ("Cymel 385", 80% solids, available from Cytec) are added to this mixture. This mixture is added to the above-described fragrance oil-in-water emulsion with stirring, at a temperature of 45 ° C. High speed mixing is employed to achieve a mean particle size volume of 15 microns. The temperature of the mixture gradually rises to 65 ° C, and is maintained at this temperature overnight, with permanent agitation to start and complete encapsulation. To form the capsule shell of the acrylic acid-alkylacrylate copolymer, the alkyl group can be selected from ethyl, propyl, butyl, amyl.hexyl, cyclohexyl,
2-ethylhexyl or other alkyl groups having from one to about sixteen carbons, preferably from one to eight carbons.
Example 3
A 9 kg aliquot of perfume microcapsule paste from Examples 1 is mixed using a Eurostar mixer (IKA) with an R1382 accessory at a constant rate of 200 RPM. For the aliquot, 5.4 g of ethylenediamine disuccinic acid (EDDS) are added, followed by 500 g of carboxymethyl cellulose (CP Kelco), while mixing using the Eurostar mixer with the same accessory and speed as described above. The grout is mixed for a total of two hours or until a uniform paste is formed.
Example 4
A 9 kg aliquot of perfume microcapsule paste from Examples 2 is mixed using a Eurostar mixer (IKA) with an R1382 accessory at a constant rate of 200 RPM. For the aliquot, 500 g of carboxymethyl cellulose (CP Kelco) are added, while mixing using the Eurostar mixer with the same accessory and speed as described above. The grout is mixed for a total of two hours or until a uniform paste is formed.
<img file="MX337136B_D0058.tif" />
Example 5
1.28 kg of Sipernat® 22S precipitated silica (Degussa) are added to an F-20 paddle mixer (Forberg). Mixing is initially carried out for 5 seconds to distribute the silica evenly at the base of the mixer. The mixer is stopped and 8.25 kg of pulp, manufactured in accordance with Example 2, are distributed evenly into the powder. The mixer is then run at 120 rpm for a total of 30 seconds. After mixing, the wet particles are removed from the mixer and subjected to revision using a 2000 micron sieve to remove oversize. The product passing through the screen is dried in 500 g batches in a CDT 0.02 fluidized bed drier (Niro) to a final moisture content of 20% by weight, measured with a Kart Fischer instrument. The dryer is operated at an inlet temperature of 140 ° C and an air speed of 0.68 m / s.
Examples 6-13
The following are examples of laundry detergent compositions comprising the perfume composition.
<img file="MX337136B_D0059.tif" />
<td rowspan="2">Raw material</td><td colspan="8">% w / w laundry detergent compositions</td>
<td> 6</td><td> 7</td><td> 8</td><td> 9</td><td> 10</td><td> 11</td><td> 12</td><td> 13</td>
<td>Linear alkylbenzenesulfonate</td><td> 7.1</td><td> 6.7</td><td> 11.0</td><td> 10.6</td><td> 6.9</td><td> 4.5</td><td> 10.1</td><td> 8.9</td>
<td>C12-15 sodium ethoxy alkyl sulfate having an ethoxylation degree molar average of 3</td><td> 3.5</td><td> 0.0</td><td> 1.5</td><td> 0.0</td><td> 0.0</td><td> 0.0</td><td> 0.0</td><td> 1.9</td>
<td>Acrylic / Maleic Acid Copolymer</td><td> 3.6</td><td> 1.8</td><td> 4.9</td><td> 2.0</td><td> 1.0</td><td> 1.6</td><td> 3.9</td><td> 2.3</td>
<td>Sodium aluminosilicate (zeoiite 4A)</td><td> 4.0</td><td> 0.5</td><td> 0.8</td><td> 1.4</td><td> 16.3</td><td> 0.0</td><td> 17.9</td><td> 2.4</td>
<td>Sodium tripolyphosphate</td><td> 0.0</td><td> 17.5</td><td> 0.0</td><td> 15.8</td><td> 0.0</td><td> 23.3</td><td> 0.0</td><td> 0.0</td>
<td>Sodium carbonate</td><td> 23.2</td><td> 16.8</td><td> 30.2</td><td> 17.3</td><td> 18.4</td><td> 9.0</td><td> 20.8</td><td> 30.0</td>
<td>Sodium sulfate</td><td> 31.4</td><td> 29.4</td><td> 35.5</td><td> 7.2</td><td> 26.3</td><td> 42.8</td><td> 33.2</td><td> 28.3</td>
<td>Sodium silicate</td><td> 0.0</td><td> 4.4</td><td> 0.0</td><td> 4.5</td><td> 0.0</td><td> 6.1</td><td> 0.0</td><td> 4.6</td>
<td>C14-15 ethoxylated alkyl alcohol having an average molar grade of 7</td><td> 0.4</td><td> 2.6</td><td> 0.8</td><td> 2.5</td><td> 3.1</td><td> 0.3</td><td> 3.8</td><td> 0.4</td>
<td>Sodium percarbonate</td><td> 16.0</td><td> 0.0</td><td> 8.4</td><td> 20.4</td><td> 13.1</td><td> 3.6</td><td> 0.0</td><td> 7.0</td>
<td>Sodium perborate</td><td> 0.0</td><td> 9.9</td><td> 0.0</td><td> 0.0</td><td> 0.0</td><td> 0.0</td><td> 0.0</td><td> 0.0</td>
<td>Tetraacetlethylenediamine (TAED)</td><td> 2.2</td><td> 1.7</td><td> 0.0</td><td> 4.7</td><td> 3.6</td><td> 0.0</td><td> 0.0</td><td> 0.8</td>
<td>Calcium bentonite</td><td> 0.0</td><td> 0.0</td><td> 0.0</td><td> 1.8</td><td> 0.0</td><td> 0.0</td><td> 0.0</td><td> 5.6</td>
<td>Citric acid</td><td> 2.0</td><td> 1.5</td><td> 2.0</td><td> 2.0</td><td> 2.5</td><td> 1.0</td><td> 2.5</td><td> 1.0</td>
<td>Protease (84 mg active / g)</td><td> 0.14</td><td> 0.12</td><td> 0.0</td><td> 0.12</td><td> 0.09</td><td> 0.08</td><td> 0.10</td><td> 0.08</td>
<td>Amylase (21.55 mg active / g)</td><td> 0.10</td><td> 0.11</td><td> 0.0</td><td> 0.10</td><td> 0.10</td><td> 0.0</td><td> 0.14</td><td> 0.08</td>
<td>Lipase (11.00 mg active / g)</td><td> 0.70</td><td> 0.50</td><td> 0.0</td><td> 0.70</td><td> 0.50</td><td> 0.0</td><td> 0.0</td><td> 0.0</td>
<td>Cellulase (2.3 mg active / g)</td><td> 0.0</td><td> 0.0</td><td> 0.0</td><td> 0.0</td><td> 0.0</td><td> 0.0</td><td> 0.18</td><td> 0.0</td>
<td>Beneficial Agent Composition of Example 3</td><td> 1.4</td><td> 0.6</td><td> 0.8</td><td> 1.0</td><td> 0.7</td><td> 0.3</td><td> 0.7</td><td> 1.2</td>
<td>Water and miscellaneous</td><td colspan="8">csp 100%</td>
The equipment and materials described in Examples 1 to 13 can be obtained from the following suppliers: IKA Werke GmbH & Co. KG, Staufen, Germany; CP Kelco, Atlanta, United States; Forberg International AS, Larvik, Norway; Degussa GmbH, Dusseldorf, Germany; Niro A / S, Soeberg, Denmark; Baker Perkins Ltd, Peterborough, UK; Nippon Shokubai, Tokyo, Japan; BASF, Ludwigshafen, Germany; Braun, Kronberg, Germany; Industrial Chemicals Limited, Thurrock, UK; Primex ehf, Siglufjordur, Iceland; ISP World Headquarters; Polysciences, Inc. from Warrington, Pennsylvanla, United States; Cytec Industries Inc., New
<img file="MX337136B_D0060.tif" />
Jersey, United States; International Specialty Products, Wayne, New Jersey, United States; P&G Chemicals Americas, Cincinnati, Ohio, United States; Sigma-Aldrich Corp., St. Louis, Missouri, United States.
The dimensions and values described in the present description are not to be understood as strictly limited to the exact numerical values mentioned. Instead, unless otherwise specified, each of those dimensions will mean both the mentioned value as well as a functionally equivalent range comprising that value. For example, a dimension described as "40mm" refers to "about 40mm".
All documents cited in the Detailed Description of the Invention are, in part relevant, incorporated in the present description by reference; citation of any document is not to be construed as an admission that is from the prior industry with respect to the present invention. To the extent that any meaning or definition of a term in this document contradicts any meaning or definition of the same term in a document incorporated by reference, the meaning or definition assigned to that term in this document shall prevail.
Although particular embodiments of the present invention have been illustrated and described, it will be apparent to persons with experience in the industry that various changes and modifications can be made without departing from the spirit and scope of the invention. Therefore, it has been attempted to cover
<img file="MX337136B_D0061.tif" />
in the appended claims all changes and modifications that are within the scope of this invention.
T
Contents267
61 sheets
Sheet 1 Sheet 2 Sheet 3 Sheet 4 Sheet 5 Sheet 6 Sheet 7 Sheet 8 Sheet 9 Sheet 10 Sheet 11 Sheet 12 Sheet 13 Sheet 14 Sheet 15 Sheet 16 Sheet 17 Sheet 18 Sheet 19 Sheet 20 Sheet 21 Sheet 22 Sheet 23 Sheet 24 Sheet 25 Sheet 26 Sheet 27 Sheet 28 Sheet 29 Sheet 30 Sheet 31 Sheet 32 Sheet 33 Sheet 34 Sheet 35 Sheet 36 Sheet 37 Sheet 38 Sheet 39 Sheet 40 Sheet 41 Sheet 42 Sheet 43 Sheet 44 Sheet 45 Sheet 46 Sheet 47 Sheet 48 Sheet 49 Sheet 50 Sheet 51 Sheet 52 Sheet 53 Sheet 54 Sheet 55 Sheet 56 Sheet 57 Sheet 58 Sheet 59 Sheet 60 Sheet 61
52 members in 13 offices
Priority claims19
| Document | Office | Kind | Date |
|---|---|---|---|
| 25887409 | United States of America | P | |
| 25887409 | United States of America | P | |
| 25890009 | United States of America | P | |
| 25890009 | United States of America | P | |
| 61258874 | United States of America | – | |
| 61258900 | United States of America | – | |
| 31192810 | United States of America | P | |
| 31192810 | United States of America | P | |
| 61311928 | United States of America | – | |
| 2010055394 | United States of America | W | |
| 2010055394 | United States of America | W | |
| 61258874 | – | – | – |
| 61258900 | – | – | – |
| 61311928 | – | – | – |
| US1055394 | – | – | – |
| US20090258874P | – | – | – |
| US20090258900P | – | – | – |
| US20100311928P | – | – | – |
| WO2010US55394 | – | – | – |
Members52
| Document | Office | Kind | |
|---|---|---|---|
| CA2778251A1 | Canada | A1 | |
| US2011107524A1 | United States of America | A1 | |
| US2011110993A1 | United States of America | A1 | |
| US2011111999A1 | United States of America | A1 | |
| WO2011056904A1 | World Intellectual Property Organization (WIPO) | A1 | |
| WO2011056934A1 | World Intellectual Property Organization (WIPO) | A1 | |
| WO2011056935A1 | World Intellectual Property Organization (WIPO) | A1 | |
| AR078889A1 | Argentina | A1 | |
| AR078890A1 | Argentina | A1 | |
| AR080330A1 | Argentina | A1 | |
| MX2012005266A | Mexico | A | |
| MX2012005270A | Mexico | A | |
| CN102597203A | China | A | |
| CN102597205A | China | A | |
| CN102612553A | China | A | |
| EP2496678A1 | European Patent Office (EPO) | A1 | |
| EP2496681A1 | European Patent Office (EPO) | A1 | |
| EP2496682A1 | European Patent Office (EPO) | A1 | |
| US8357649B2 | United States of America | B2 | |
| JP2013509988A | Japan | A | |
| MX2012005272A | Mexico | A | |
| US8759275B2 | United States of America | B2 | |
| US2014249069A1 | United States of America | A1 | |
| US9011887B2 | United States of America | B2 | |
| US2015191682A1 | United States of America | A1 | |
| JP2015155540A | Japan | A | |
| CN102597205B | China | B | |
| CN105107438A | China | A | |
| CA2778251C | Canada | C | |
| MX337136BThis record | Mexico | B | |
| HK1212281A1 | Hong Kong, China | A1 | |
| BR112012011580A2 | Brazil | A2 | |
| CN102612553B | China | B | |
| US2016348043A1 | United States of America | A1 | |
| US2016376535A1 | United States of America | A1 | |
| CN105107438B | China | B | |
| BR112012010650A2 | Brazil | A2 | |
| EP2496681B1 | European Patent Office (EPO) | B1 | |
| EP3255135A1 | European Patent Office (EPO) | A1 | |
| ES2647570T3 | Spain | T3 | |
| EP2496678B1 | European Patent Office (EPO) | B1 | |
| PL2496681T3 | Poland | T3 | |
| JP2018172687A | Japan | A | |
| JP6430282B2 | Japan | B2 | |
| EP3255135B1 | European Patent Office (EPO) | B1 | |
| EP2496682B1 | European Patent Office (EPO) | B1 | |
| TR201907815T4 | Türkiye | T4 | |
| PL3255135T3 | Poland | T3 | |
| BR112012010676A2 | Brazil | A2 | |
| BR112012010650B1 | Brazil | B1 | |
| BR112012011580B1 | Brazil | B1 | |
| EP2496678B2 | European Patent Office (EPO) | B2 |
1 legal event, as the office reported them to INPADOC
Events
| Event | Code | |
|---|---|---|
| Grant or registrationFG | FG |
Numbers
- Publication
- 337136
- Publication, DOCDB
- 337136
- Publication, EPODOC
- MX337136
- Application
- 2012005272
- Application, DOCDB
- 2012005272
- Application, EPODOC
- MX20120005272
Titles
- Spanish
- PARTICULA DE SUMINISTRO.
Classification
- CPC, 29
- C11D17/0039
- A01N25/28
- A61K8/11
- A61K8/731
- A61K8/8147
- A61K2800/412
- A61Q19/00
- B01J13/22
- C09B67/0097
- A23P10/30
- A23L27/72
- C11D3/505
- C11B9/00
- C11B9/0023
- A61P31/04
- C11D2111/12
- C11D3/225
- C11D3/3703
- A61K8/585
- A61K8/8152
- A61Q5/02
- B01J13/06
- C11D1/12
- C11D1/29
- C11D3/001
- C11D3/2044
- C11D3/373
- C11D17/06
- C11D3/3723
- IPC, 5
- C11D17 00
- A61K8 11
- B01J13 02
- C11D3 50
- A23L27 00