Nova Patents
LTIP1818A

A gene encoding neurothropin-3, gene products and process for preparing thereof

Abstract

The present invention relates to nucleic acid sequences encoding brain derived neurotrophic factor (BDNF), as well as BDNF protein produced in quantity using these nucleic acid sequences, as well as fragments and derivatives thereof. In addition, the invention relates to pharmacologic compositions and therapeutic uses of BDNF, having provided, for the first time, the ability to generate sufficient quantities of substantially pure BDNF for clinical use. The invention also relates to antibodies directed toward BDNF or fragments thereof, having provided a method for generating sufficient immunogen. Further, by permitting a comparison of the nucleic acid sequences of BDNF and NGF, the present invention provides for the identification of homologous regions of nucleic acid sequence between BDNF and NGF, thereby defining a BDNF/NGF gene family; the invention provides a method for identifying an disolating additional members of this gene family.

Term

No projected expiry on record.

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111 members in 28 offices

This recordMember, by publication datePriority claim18 more offices are in the list below

Priority claims3

Priority claims
DocumentOfficeKindDate
40059189United States of AmericaA
400591–––
US19890400591–––

Members111

Family members, oldest first
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CA2040412A1CanadaA1
CA2040437A1CanadaA1
IE903128A1IrelandA1
IE903129A1IrelandA1
WO9103568A1World Intellectual Property Organization (WIPO)A1
WO9103569A1World Intellectual Property Organization (WIPO)A1
AU6337390AAustraliaA
AU6404990AAustraliaA
NO911688D0NorwayD0
NO911689D0NorwayD0
PT95152APortugalA
PT95153APortugalA
NO911688LNorwayL
CN1052141AChinaA
CN1052142AChinaA
NO911689LNorwayL
ZA906926BSouth AfricaB
ZA906927BSouth AfricaB
IL95511D0IsraelD0
IL95512D0IsraelD0
EP0440777A1European Patent Office (EPO)A1
EP0441947A1European Patent Office (EPO)A1
GR900100647AGreeceA
GR900100653AGreeceA
DD299196A5German Democratic Republic (until 1990)A5
DD299197A5German Democratic Republic (until 1990)A5
EP0440777A4European Patent Office (EPO)A4
EP0441947A4European Patent Office (EPO)A4
KR920701432ARepublic of KoreaA
KR920702865ARepublic of KoreaA
US5180820AUnited States of AmericaA
GR1000980BGreeceB
IL104726D0IsraelD0
JPH05161493AJapanA
US5229500AUnited States of AmericaA
CA2130115A1CanadaA1
WO9315608A1World Intellectual Property Organization (WIPO)A1
AU3619493AAustraliaA
ZA93999BSouth AfricaB
NZ235086ANew ZealandA
AU643705B2AustraliaB2
JPH05328974AJapanA
PT95153BPortugalB
CN1080188AChinaA
AU647412B2AustraliaB2
LV10725ALatviaA
LTIP1546ALithuaniaA
US5438121AUnited States of AmericaA
JPH07507053AJapanA
LV10792ALatviaA
EP0671879A1European Patent Office (EPO)A1
LTIP1818AThis recordLithuaniaA
US5453361AUnited States of AmericaA
GR1002052BGreeceB
LV10725BLatviaB
LV10792BLatviaB
EP0671879A4European Patent Office (EPO)A4
LT4011BLithuaniaB
LT4063BLithuaniaB
EP0440777B1European Patent Office (EPO)B1
AT148921TAustriaT
DE69029934D1GermanyD1
DK0440777T3DenmarkT3
ES2098271T3SpainT3
EP0441947B1European Patent Office (EPO)B1
AT153074TAustriaT
AU677951B2AustraliaB2
DE69030719D1GermanyD1
ES2100891T3SpainT3
DE69029934T2GermanyT2
US5667968AUnited States of AmericaA
DE69030719T2GermanyT2
SG46954A1SingaporeA1
PT95152BPortugalB
NO303584B1NorwayB1
JP2783450B2JapanB2
NO303694B1NorwayB1
SK279660B6SlovakiaB6
SK279668B6SlovakiaB6
SK422990A3SlovakiaA3
SK423090A3SlovakiaA3
HK1006578A1Hong Kong, ChinaA1
HK1006579A1Hong Kong, ChinaA1
RU2128226C1Russian FederationC1
HK1008292A1Hong Kong, ChinaA1
KR100188189B1Republic of KoreaB1
KR100196203B1Republic of KoreaB1
CZ422990A3CzechiaA3
RU2131926C1Russian FederationC1
CZ423090A3CzechiaA3
CZ285649B6CzechiaB6
CZ286015B6CzechiaB6
SG70560A1SingaporeA1
EP0671879B1European Patent Office (EPO)B1
AT193207TAustriaT
DE69328730D1GermanyD1
IL104726AIsraelA
FI105342BFinlandB
FI105343BFinlandB
DE69328730T2GermanyT2
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