Method of achieving improved hair feel

0001A method of achieving improved hair feel, with (a) certain cationic guar polymers and (b) certain cationic copolymers and (c) anti-fluffy active substances and (d) cosmetically acceptable carriers. (E) Including the step of applying the composition containing the coacervate to the hair, the total of (a): (b) is about 1000: 1 to about 3.5: 1 of the whole composition, and (a) + The total amount of (b) is about 0.0001% by weight to about 0.7% by weight of the whole composition, and when the composition is diluted with water, coacervate particles are formed, and the coacervate particles are about 1cP to about 100cP. It has a squeeze viscosity, a floc size of more than about 20 micrometers, a coacervate particle percentage of about 1% to about 60%, and an antifungal active substance adhesion on the scalp of at least about 1 microgram / cm.²Is.

0002Conditioning shampoos, i.e., hair products that "have two functions in one (2 in 1)" containing a surfactant and a hair conditioning agent are known. These personal care compositions typically include anionic cleaning surfactants, as well as conditioning agents such as silicones, hydrocarbon oils, and fatty esters. These products have become popular among consumers as a convenient means of obtaining hair conditioning and cleaning performance from a single product.

0003However, many conditioning personal care compositions do not adequately adhere the conditioning agent to the hair or skin during the application process. Further, even if it can be attached, it can be attached only when the concentration of the anionic surfactant in the formulation is relatively low. Insufficient adhesion results in little or no conditioning benefit, as most of the conditioning agent is washed off during the coating process. If the conditioning agent does not adhere sufficiently to the hair or skin, a relatively high concentration of conditioning agent may be required. However, such high concentrations of conditioning agents can increase raw material costs, reduce foaming, and raise concerns about product stability. In addition, limiting the total anionic surfactant so that coacervates are formed may also limit the foaming capacity of the composition. Otherwise, even with the use of low cost efficient amphoteric surfactants, it may be necessary to increase their concentration to ensure sufficient foaming.

0004One of the known methods for improving the adhesion of the hair conditioning agent to the hair includes the use of certain cationic adhesion polymers. These polymers may be synthetics, but most commonly are natural cellulose derivatives or guar polymers modified with cation substituents.

0005To improve the adhesion of various conditioning actives, especially those with small droplet diameters (ie, 2 micrometers or less), it is important to form a coacervate when the cleaning composition is diluted with water. Is. For the purpose of coacervate formation, cleaning compositions containing typical cationic polymers tend to significantly limit the concentration of total anionic surfactant in order to ensure a sufficient coacervate particle concentration upon dilution. However, this limits the amount of foaming that can be achieved with a particular cleaning composition. Therefore, in order to increase the cost efficiency and foamability of the coacervate-forming composition, it is desirable to use a cationic polymer capable of forming coacervates in the presence of a high concentration of anionic surfactant. However, further complexity arises when the composition contains an antidandruff active substance that is also required to adhere to the scalp in an effective amount and quality. However, for the purpose of increasing the adhesion and quality of anti-dandruff active substances, for example, if a high concentration and high charge density cationic polymer is used, the hair conditioning feel is often unacceptable to many consumers. Associate with.

<p num="0006"> As a result, there is a need for anti-dandruff compositions for conditioning that improve the adhesion of anti-dandruff, without the trade-off between hair conditioning and hair feel.</p>

<p num="0007"> According to the first aspect, the present invention relates to a method for improving the feel of hair. (a) A cationic guar polymer having a weight average molecular weight of less than about 1,000,000 g / mol and a charge density of about 0.1 meq / g to about 2.5 meq / g. (b) With the copolymer which is a cationic copolymer of an acrylamide monomer and a cationic monomer and has a charge density of about 1.0 meq / g to about 3.0 meq / g. (c) Anti-dandruff active substance and (d) Acceptable carriers for cosmetics, (e) Including a step of applying a composition containing a surfactant to hair. The weight ratio of (a): (b) is about 1000: 1 to about 3.5: 1. The sum of (a) + (b) is about 0.0001% by weight to about 0.7% by weight of the whole composition. The composition forms coacervate particles when diluted with water and Coacervate particles have a squeeze viscosity of about 1 cP to about 100 cP, The percentage of coacervate particles with a floc size of more than about 20 micrometers is about 1% to about 60%. Adhesion of antidandruff actives on the scalp is at least about 1 microgram / cm²Is.</p><p num="0008"> According to the second aspect, the present invention (a) A cationic guar polymer having a weight average molecular weight of less than about 1,000,000 g / mol and a charge density of about 0.1 meq / g to about 2.5 meq / g. (b) With the copolymer which is a cationic copolymer of an acrylamide monomer and a cationic monomer and has a charge density of about 1.0 meq / g to about 3.0 meq / g. (c) Anti-dandruff active substance and (d) Acceptable carriers for cosmetics, (e) Including a step of applying a composition containing a surfactant to hair. The weight ratio of (a): (b) is about 1000: 1 to about 3.5: 1. And the total of (a) + (b) is about 0.0001% by weight to about 0.7% by weight of the whole composition.</p><p num="0009"> According to a third aspect, the present invention relates to the use of the composition according to the second aspect for the purpose of treating hair.</p><p num="0010"> According to the fourth aspect, the present invention (a) Application instructions including the method according to the first aspect, (b) The composition and the kit comprising.</p>

0011<figref num="1">Axis X: 100s^-1It is the squeezed viscosity of the coacervate particles in. Axis Y: Percentage of coacervate particles with a flock size greater than about 20 micrometers. The size of the circle corresponds to the average consumer acceptance score (the larger the size, the higher the acceptance score). Circles filled with white have an average consumer acceptance score of 60 or higher, and the ratio of (a): (b) falls within the range of about 1000: 1 to about 3.5: 1, (a) + ( b) The total is less than 0.7%, and the adhesion of antidandruff active substance on the scalp is 1 microgram / cm.²Represents a composition having super-coacervate particle properties. Circles filled with light gray indicate that less than 0.7% of the compositions exceed (a) + (b). Circles filled with dark gray and black represent compositions in which the ratio of (a): (b) falls outside the range of 1000: 1 to 3.5: 1.</figref>

0012Unless otherwise stated, all percentages are based on the total weight of the composition. All ratios are weight ratios unless otherwise stated. All ranges are inclusive and combinable. The number of significant digits does not represent a limitation on the quantity displayed, nor does it represent a limitation on the accuracy of the measurements. As used herein, the term "molecular weight" or "M.Wt." Refers to weight average molecular weight unless otherwise stated. "QS" means an amount sufficient to be 100%.

0013Unless otherwise indicated, all quantities are understood to be modified by the word "about". Unless otherwise indicated, all measurements are understood to be performed in ambient conditions at 25 ° C, and "ambient conditions" means conditions at about 1 atmosphere and about 50% relative humidity. All of these weights for the listed ingredients are based on activity level and do not include bases or by-products that may be contained in commercially available materials unless otherwise noted.

0014As used herein, "included" means that other steps and other components may be added that do not affect the final result. The term includes the term "consisting of" and the term "consisting of ~ essentially". The compositions, methods, uses, kits, and processes of the invention are the essential elements and limitations of the invention described herein, as well as any additional or optional components, components described herein. , Processes, or constraints, consisting of them, and can consist essentially of them.

0015The term "substantially free" as used herein is less than about 1% by weight, or less than about 0.8% by weight, or less than about 0.5% by weight, or less than about 0.3% by weight, or less than about 0.3% by weight of the total composition. It means about 0% by weight.

0016As used herein, the term "hair" refers to mammalian hair, including scalp hair, facial hair, and body hair, and particularly refers to hair on the human head and scalp.

0017As used herein, the term "cosmetologically acceptable" means that the composition, formulation, or ingredient described does not involve excessive toxicity, maladaptation, instability, and allergic reactivity. Means that it is suitable for use in contact with human keratin tissue. All compositions described herein and having a use for direct application to keratin tissue are limited to be cosmetically acceptable.

0018Examples of the "derivative" used in the present specification include amide derivatives, ether derivatives, ester derivatives, amino derivatives, carboxyl derivatives, acetyl derivatives, acid derivatives, salt derivatives and / or alcohol derivatives of a predetermined compound. , Not limited to these.

0019As used herein, "polymer" means a chemical substance formed by the polymerization of two or more monomers. As used herein, the term "polymer" should include the polymerization of monomers, as well as all materials made from natural polymers. Polymers made from only one type of monomer are called homopolymers. The polymer contains at least two monomers. Polymers made from two or more different types of monomers are referred to as copolymers. The distribution of different monomers can be calculated statistically or block by block, both possibilities are suitable for the present invention. Unless otherwise specified, the term "polymer" as used herein includes any type of polymer, including homopolymers and copolymers.

0020As used herein, "kit" means a package unit that includes a plurality of components. Examples of kits include, for example, a first composition and a separately packaged second composition. Another kit may include a first composition and an energy delivery device. Another kit may include three different types of separately packaged compositions and hair styling tools. Further kits may include application instructions, including methods, and compositions / formulations.

0021As used herein, the term "coacervate" means a complex formed between a surfactant and a polymer. The complex may be soluble or insoluble in the undiluted composition, typically when an insoluble complex is formed in the undiluted composition and diluted. It may be difficult to dissolve, thus increasing the level of its phase separation or adhesion in solution.

0022As used herein, the term "flock" means localized clusters of aggregated insoluble coacervates, such as polymers, surfactants, water and those present in compositions such as antifocal active substances and silicone emulsions. It is composed of a dispersed phase. All of the flock sizes disclosed herein are obtained using the Lasentec FBRM method described below.

0023As used herein, the term "isotropic" means a particular phase structure of coacervates, where the structure is identical along any three orthogonal directions in space and therefore. , Dark or "non-birefringent" when viewed between orthogonally polarized light. (If the first vector component is zero in the second direction, one direction is "orthogonal" with respect to the other.) (Laughlin, RG (1994). "The Aqueous Phase Behavior of Surfactants," 182,8.2).

0024As used herein, the term "charge density" refers to the ratio of the number of positive charges in a monomer unit (composed of a polymer) to the M.Wt. In the monomer unit. Multiplying the polymer M.Wt. by the charge density gives the number of positively charged sites in a given polymer chain. The charge density of cationic guar is measured using standard elemental analysis of nitrogen percentage known to those of skill in the art. This nitrogen percentage value can be used to calculate the number or equivalent of positive charges per gram of polymer after being modified for total protein content analysis. The charge density of cationic copolymers is a function of the monomers used in the synthesis. Standard NMR techniques known to those of skill in the art are used to determine the ratio of cationic and nonionic monomers in a polymer. This technique is then used to calculate the number or equivalent of positive charges per gram of polymer. Once these values are determined, the charge density is reported in milligram equivalents (meq) per gram of cationic polymer.

0025As used herein, the term "(meth) acrylamide" means methyl acrylamide or acrylamide. As used herein, the term "(meth) acrylic acid" means acrylic acid or methacrylic acid.

0026Surprisingly, by prescribing specific concentrations and ratios of specific cationic guar polymers and specific cationic copolymers of acrylamide and cationic monomers, consumer rejection of hair conditioning and hair feel It has been found that antidandruff active substances can be improved with minimal or without any consumer refusal.

0027Without being bound by theory, low concentrations of cationic copolymers relative to cationic dandruff polymers are required for good consumer acceptance of hair conditioning and hair feel, but nonetheless. The inventors have found that the antidandruff active substance adheres well to the scalp. Such excellent adhesion to the scalp correlates with the antidandruff effect of the antidandruff active substance. The coacervate produced by the cationic guar has highly desirable coacervate floc size and coacervate rheological properties. The reason these are highly desirable is that their properties correlate with consumer acceptance of the resulting hair conditioning and hair feel. Depending on the cationic guar, even if the given hair feel is acceptable to the consumer, it may not be effective in adhering the antidandruff active substance. It has been clarified that if the molecular weight of the cationic guar is increased, the effect of preventing dandruff adhesion on the scalp can be improved, but as a result, the floc size of the coacervate may be increased. When a large coacervate floc is applied to the hair, it adheres to the hair, resulting in a less receptive hair feel. Cationic copolymers, on the other hand, produce coacervates that are highly effective in adhering anti-dandruff active substances onto the scalp, resulting in coacervate floc size and rheological properties resulting in a consumer-unacceptable hair feel. Become. To provide a composition comprising a particular cationic guar and a particular cationic copolymer in the proportions and amounts specified herein, a single composition with reduced molecular weight of the cationic guar and the cationic copolymer. And increased silicone adhesion can achieve both the benefits desired by the consumer. At the same time, the hair conditioning performance and consumer acceptance of the hair feel are still highly maintained. This was a surprising discovery.

0028The features of the method with the first aspect, the other aspect, and other related components are described in detail herein. All ingredients described herein should be physically and chemically compatible with the essential ingredients described herein, otherwise excessively product stability, aesthetics or It must not impair performance.

0029The composition comprises (a) a cationic guar polymer having a less than weight average molecular weight of about 1,000,000 g / mol and a charge density of about 0.1 meq / g to about 2.5 meq / g. The total of (a) + (b) is about 0.0001% by weight to about 0.7% by weight of the whole composition. The cationic guar polymer is a cationically substituted galactomannan (guar) gum derivative. The guar gum used in the preparation of these guar gum derivatives is typically obtained as a naturally occurring material from guar plant seeds. The guar molecule itself is a linear chain mannan that branches at regular intervals with a single galactose unit on the alternative mannose unit. The mannose units are linked to each other by β (1-4) glucosidic bonds. Galactose branching is caused by α (1-6) bonds. The cationic derivative of guar rubber is obtained by the reaction between polygalactomannan and the hydroxyl group of the reactive quaternary ammonium compound. The degree of substitution of cationic groups on the guar structure must be sufficient to provide the required cationic charge densities described above.

0030In certain embodiments, the cationic guar polymer is less than 900,000 g / mol, or about 150,000 to about 800,000 g / mol, or about 200,000 to about 700,000 g / mol, or about 300,000 to about 700,000 g / mol, or about 400,000. It has a weight average molecular weight of ~ about 600,000 g / mol.

0031In certain embodiments, the composition comprises the cationic guar polymer (a) from about 0.01% to about 0.7% by weight, or about 0.04% to about 0.55% by weight, or about 0.08% by weight of the total composition. Includes ~ about 0.5% by weight, or about 0.16% by weight ~ about 0.5% by weight, or about 0.2% by weight ~ about 0.5% by weight, or about 0.3% by weight ~ about 0.5% by weight, or about 0.4% by weight ~ about 0.5% by weight ..

0032Cationic guar polymers can be formed from quaternary ammonium compounds. In certain embodiments, the quaternary ammonium compound for forming a cationic guar polymer conforms to the following general formula:

0033<chemistry num="1"><img id="000002" he="19" wi="128" file="JP5890528B2_D0001.tif" img-format="tif" img-content="drawing" /></chemistry> In the formula, R¹, R²And R³Is a methyl or ethyl group, R⁴Is an epoxy alkyl group of the following general formula?

0034<chemistry num="2"><img id="000003" he="11" wi="128" file="JP5890528B2_D0001.tif" img-format="tif" img-content="drawing" /></chemistry> Or R⁴Is a halohydrin group of the following general formula.

0035<chemistry num="3"><img id="000004" he="12" wi="128" file="JP5890528B2_D0001.tif" img-format="tif" img-content="drawing" /></chemistry> In the formula, R⁵Is C₁~ C₃It is alkylene, X is chlorine or bromine, Z is Cl-, Br-, I- or HSO₄-It is an anion like.

0036In certain embodiments, the cationic guar polymer conforms to the following general formula:

0037<chemistry num="4"><img id="000005" he="19" wi="128" file="JP5890528B2_D0001.tif" img-format="tif" img-content="drawing" /></chemistry> In the formula, R is guar gum and R¹, R², R³And R⁵Is a hydrocarbon containing 1 to 6 carbon atoms and Z is a halogen. In certain embodiments, the cationic guar polymer fits the formula G.

0038<chemistry num="5"><img id="000006" he="21" wi="128" file="JP5890528B2_D0001.tif" img-format="tif" img-content="drawing" /></chemistry>

0039Suitable cationic guar polymers include cationic guar gum derivatives such as guar hydroxypropyl trimonium chloride. In certain embodiments, the cationic guar polymer is guarhydroxypropyltrimonium chloride. Specific examples of guar hydroxypropyl trimonium chloride include the Jaguar® series commercially available from Rhone-Poulenc Incorporated, such as the Jaguar® C-500 commercially available from Rhodia. Jaguar® C-500 has a charge density of 0.8 meq / g and an M.W t. Of 500,000 g / mole. Another guar-hydroxypropyltrimonium chloride (with a charge density of 1.1 meq / g and an M.Wt. of 500,000 g / mole) is available from Ashland. Additional guar-hydroxypropyltrimonium chloride (with a charge density of 1.5 meq / g and an M.Wt. of 500,000 g / mole) is available from Ashland.

0040Jaguar® C-17 is not suitable as the cationic guar polymer (a) of the present invention. Jaguar® C-17 conforms to Formula G, has a cationic charge density of about 0.6 meq / g, and has an M.Wt. Of about 22 million g / mol, and is available from the Rhodia Company. Jaguar® C 13S is also not suitable as the cationic guar polymer (a) of the present invention. Jaguar® C 13S conforms to Formula G and has a M.Wt. of approximately 2,200,000 g / mol and a cationic charge density of approximately 0.8 meq / g (available from the Rhodia Company). In certain embodiments, the present invention is substantially free of Jaguar® C-17 and / or Jaguar® C 13S.

0041Other suitable polymers include Hi-Care 1000 available from Rhodia with a charge density of 0.7 meq / g and an M.Wt. of 600,000 g / mole, and a charge density of 0.7 meq / g, and 425,000 g. Included are N-Hance 3269 and N-Hance 3270 available from Ashland with / mole M.Wt. AquaCat CG518 is available from Ashland with a charge density of 0.9 meq / g and an M.W t. Of 50,000 g / mole. AquaCat CG518 is available from Ashland with a charge density of 0.9 meq / g and an M.W t. Of 50,000 g / mole.

0042The composition is (b) a cationic copolymer of an acrylamide monomer and a cationic monomer, which has a charge density of about 1.0 meq / g to about 3.0 meq / g. The total of (a) + (b) is about 0.0001% by weight to about 0.7% by weight of the whole composition. In certain embodiments, the cationic copolymer is a synthetic cationic copolymer of an acrylamide monomer and a cationic monomer.

0043In certain embodiments, the cationic copolymers include: (i) Acrylamide monomer of the following formula AM:

0044<chemistry num="6"><img id="000007" he="53" wi="128" file="JP5890528B2_D0001.tif" img-format="tif" img-content="drawing" /></chemistry> In the formula, R⁶Is H or C_1~4Alkyl and R⁷And R⁸Is H, C_1~4Alkyl, CH₂OCH₃, CH₂OCH₂CH (CH)₃)₂, And independently selected from the group consisting of phenyl, or both C_3~6Cycloalkyl, and (ii) Cationic monomer of the following formula CM:

0045<chemistry num="7"><img id="000008" he="57" wi="136" file="JP5890528B2_D0001.tif" img-format="tif" img-content="drawing" /></chemistry> In the equation, k = 1, each v, v'and v is an independent integer from 1 to 6, w is an integer from 0 or 1 to 10, and X.^-Is an anion.

0046In certain embodiments, the cationic monomer fits the formula CM, in which k = 1, v = 3, w = 0, z = 1, and X.^-Is Cl^-And forms the following structure.

0047<chemistry num="8"><img id="000009" he="41" wi="128" file="JP5890528B2_D0001.tif" img-format="tif" img-content="drawing" /></chemistry>

0048The above structure may be referred to as a diquat. In another embodiment, the cationic monomer fits the formula CM, where v and v are 3 respectively, v'= 1, w = 1, y = 1, and X^-Is Cl^-And it becomes as follows.

0049<chemistry num="9"><img id="000010" he="51" wi="136" file="JP5890528B2_D0001.tif" img-format="tif" img-content="drawing" /></chemistry>

0050The above structure may be referred to as a Triquat.

0051In certain embodiments, the acrylamide monomer is acrylamide or methacrylamide.

0052In certain embodiments, the cationic copolymer (b) is AM: TRIQUAT, ie acrylamide and 1,3-propanediaminium, N- [2-[[[dimethyl [3-[(2-methyl-1oxo2). -Propenyl) Amino] Propyl] Ammonio] Acetyl] Amino] Ethyl] 2-Hydroxy-N, N, N', N', N'-Pentamethyl-, a copolymer with trichloride. AM: TRIQUAT is also known as Polyquaternium 76 (PQ76). AM: TRIQUAT has a charge density of 1.6 meq / g and can have an M.W t. Of 11 million g / mol.

0053In certain embodiments, the cationic copolymer is a synthetic cationic copolymer of an acrylamide monomer and a cationic monomer, and the cationic monomer is dimethylaminoethyl (meth) acrylate, dimethylaminopropyl (meth) acrylate, diterthiobutylamino. Ethyl (meth) acrylate, dimethylaminomethyl (meth) acrylamide, dimethylaminopropyl (meth) acrylamide, ethyleneimine, vinylamine, 2-vinylpyridine, 4-vinylpyridine, trimethylammonium ethyl chloride (meth) acrylate, trimethylammonium ethyl ( Meta) Acrylate methyl sulfate, benzyldimethylammonium ethyl chloride (meth) acrylate, 4-benzoylbenzyldimethylammonium ethyl acrylate, trimethylammonium chloride (meth) acrylamide, trimethylammonium propyl (meth) acrylamide, vinylbenzyltrimethylammonium chloride , Diaryldimethylammonium chloride, and mixtures thereof are selected from the group.

0054In certain embodiments, the cationic copolymers are cationic monomers, the cationic monomers being trimethylammonium ethyl chloride (meth) acrylate, trimethylammonium ethyl (meth) acrylate methyl sulfate, benzyl dimethylammonium ethyl chloride (meth). A cation selected from the group consisting of meth) acrylate, 4-benzoylbenzyldimethylammonium ethyl acrylate, trimethylammonium chloride (meth) acrylamide, trimethylammonium propyl (meth) acrylamide, vinyl benzyltrimethylammonium chloride, and mixtures thereof. Contains sex monomers.

0055In certain embodiments, the cationic copolymer is water soluble. In certain embodiments, the cationic copolymers are (2) copolymers of (meth) acrylamide and (meth) acrylamide-based cationic monomers and / or hydrolysis-stable cationic monomers. ) (Meta) acrylamide and a monomer containing cationic (meth) acrylic acid ester as a main component, and a monomer containing (meth) acrylamide as a main component, and / or a terpolymer of a cationic monomer stable to hydrolysis, Formed from. The monomer containing a cationic (meth) acrylic acid ester as a main component may be a cationized ester of (meth) acrylic acid containing a quaternized N atom. In certain embodiments, the cationized ester of (meth) acrylic acid containing a quaternized N atom is a dialkylaminoalkyl (meth) acrylate quaternized with C1-C3 within the alkyl and alkylene groups. In certain embodiments, the cationized ester of (meth) acrylic acid containing a quaternized N atom is a dimethylaminomethyl (meth) acrylate, dimethylaminoethyl (meth) acrylate, dimethylamino quaternized with methyl chloride. It is selected from the group consisting of ammonium salts of propyl (meth) acrylate, diethylaminomethyl (meth) acrylate, diethylaminoethyl (meth) acrylate, and diethylaminopropyl (meth) acrylate. In certain embodiments, the cationized ester of (meth) acrylic acid containing a quaternized N atom has been quaternized with an alkyl halide, or methyl chloride, or benzyl chloride, or dimethyl sulfate (ADAME-Quat). It is dimethylaminoethyl acrylate. In certain embodiments, the cationic monomer is a dialkylaminoalkyl (meth) acrylamide quaternized with C1-C3 within the alkyl and alkylene groups, if the main component is (meth) acrylamide, or With alkyl halides, or methyl chloride, or benzyl chloride, or dimethyl sulfate

0056In certain embodiments, the (meth) acrylamide-based cationic monomer is a dialkylaminoalkyl (meth) acrylamide quaternized with C1 to C3 within the alkyl and alkylene groups. In certain embodiments, the (meth) acrylamide-based cationic monomer is an alkyl halide, in particular methyl chloride, or benzyl chloride, or dimethylaminopropylacrylamide quaternized with dimethylsulfate.

0057In certain embodiments, the cationic monomer is a hydrolyzable cationic monomer. In addition to dialkylaminoalkyl (meth) acrylamide, hydrolysis-stable cationic monomers can be all monomers that can be considered stable in OECD hydrolysis tests. In certain embodiments, the cationic monomer is hydrolyzable and the hydrolyzable cationic monomer is selected from the group consisting of diallyldimethylammonium chloride and water-soluble cationic styrene derivatives.

0058In certain embodiments, the cationic copolymer is quaternized with acrylamide, 2-dimethylammonium ethyl (meth) acrylate quaternized with methyl chloride (ADAME-Q), and methyl chloride (DIMAPA-Q). It is a terpolymer with 3-dimethylammonium propyl (meth) acrylamide. In certain embodiments, the cationic copolymer is formed from acrylamide and acrylamide propyltrimethylammonium chloride. This acrylamide propyltrimethylammonium chloride has a charge density of about 1.0 meq / g to about 3.0 meq / g.

0059In certain embodiments, about 1.1meq / g to about 2.5meq / g of the cationic copolymer, or about 1.1meq / g to about 2.3meq / g, or about 1.2meq / g to about 2.2meq / g, or about. It has a charge density of 1.2 meq / g to about 2.1 meq / g, or about 1.3 meq / g to about 2.0 meq / g, or about 1.3 meq / g to about 1.9 meq / g.

0060In certain embodiments, the cationic copolymer is about 100,000 g / mol to about 2 million g / mol, or about 300,000 g / mol to about 18 million g / mol, or about 500,000 g / mol to about 16 million g / mol. , Or from about 700,000 g / mol to about 14 million g / mol, or from about 900,000 g / mol to about 12 million g / mol.

0061In certain embodiments, the cationic copolymer is a copolymer of trimethylammoniopropylmethacrylamide chloride and N-acrylamide (N-Acrylamide), also known as AM: MAPTAC. AM: MAPTAC can have a charge density of about 1.3 meq / g and an M.W t. Of about 11 million g / mol. In certain embodiments, the cationic copolymer is AM: ATPAC. AM: ATPAC can have a charge density of about 1.8 meq / g and an M.W t. Of about 11 million g / mol.

0062In certain embodiments, the cationic guar polymer (a) and the cationic copolymer (b) are added as a use / formulation to the composition. Such formulations are incorporated herein by reference in US Pat. No. 2011 / 0002868A1 (Bierganns et. Al, filed July 1, 2010). In particular, with reference to the published source of US Pat. No. 2011 / 0002868A1, paragraphs 0042-0047 describe cationic copolymers, and paragraphs 0092-0095 specifically describe cationic guar polymers. In certain embodiments, the formulation comprises a cationic guar polymer (a) and a cationic copolymer (b), the cationic copolymer being AM: APTAC. For example, a formulation of cationic guar and AM: APTAC within the scope of the invention is available from Ashland. For example, Ashland formulations (guar hydroxypropyl trimonium chloride (500,000 g / mol M.Wt, and 1.1 meq / g charge density) and AM / APTAC (1,100,000 g / mol M.Wt., And 1.8 meq). A 95: 5 formulation of (/ g charge density) is available, for example, a formulation with a ratio of cationic guar polymer (a) to cationic copolymer (b) of 19: 1.

0063The formulation may be composed of a cationic copolymer, which is used for (1) (meth) acrylamide, (meth) acrylamide-based cationic monomer, and / or hydrolysis. For copolymers of stable cationic monomers and (2) (meth) acrylamide, monomers mainly composed of cationic (meth) acrylic acid ester, and monomers mainly composed of (meth) acrylamide, and / or hydrolysis. It is formed from a stable cationic monomer terpolymer. In certain embodiments, the formulation is a combination of cationic, water-soluble, synthetic copolymers, and polygalactomannan, or polyglucomannan, which polygalactomannan and polyglucomannan are covalently attached to the polysaccharide backbone. Derived from guar containing a tetraammonium group. In certain embodiments, the degree of cation substitution (DS) of the polygalactomannan or the polyglucomannan is from about 0.03 to about 0.70. In certain embodiments, the polygalactomannan or the polyglucomannan has a charge density of about 0.1 to about 2.5 meq / g.

0064The sum of (a) + (b) is an amount of about 0.0001% to about 0.7% by weight of the whole composition. The sum of (a) + (b) is the total weight of the cationic guar polymer as defined herein and the cationic copolymer as defined herein, relative to the total weight of the composition. It means percentage. In certain embodiments, the sum of (a) + (b) is about 0.01% to about 0.7% by weight, or about 0.1% to about 0.5% by weight, or about 0.1% to about 0.4% by weight of the entire composition. It is% by weight, or about 0.2% by weight to about 0.3% by weight. (a) + (b) is the sum in the quantities defined herein. Beyond this level, the coacervate flock size will begin to become excessive and will not be fully effective. Larger flock sizes result in more coacervate particles trapped between the hair fibers and therefore do not reach the scalp efficiently, i.e. less adhere to the scalp and are less efficient. The effect will not be obtained. In a further embodiment, the sum of (a) + (b) is about 0.0001% to less than 0.6% by weight, about 0.01% to less than 0.6% by weight, or about 0.1% to about 0.1% by weight of the entire composition. Less than 0.5% by weight, or about 0.1% by weight to less than about 0.4% by weight, or about 0.2% by weight to less than about 0.3% by weight.

0065The weight ratio of (a): (b) is about 1000: 1 to about 2: 1. In certain embodiments, the weight ratio of (a): (b) is from about 1000: 1 to about 4: 1. In certain embodiments, the weight ratio of (a): (b) is from about 800: 1 to about 4: 1, or from about 500: 1 to about 4: 1, or from about 100: 1 to about 5: 1. Or about 100: 1 to about 6: 1, or about 50: 1 to about 6.5: 1, or about 50: 1 to about 7: 1, or about 50: 1 to about 8.3: 1, or about 50: 1 to It is about 16.7: 1.

0066The pH of the composition may be from about pH 3 to about pH 9, or from about pH 4 to about pH 7.

0067The composition comprises an anti-dandruff active substance, which can be fine particles of the anti-dandruff active substance. In certain embodiments, the antidandruff active agent is selected from the group consisting of pyridinethion salts; zinc carbonate; azoles such as ketoconazole, econazole and erbiol; selenium sulfide; granular sulfur; keratolytic agents such as salicylic acid; and mixtures thereof. Will be done. In certain embodiments, the antidandruff microparticle is a pyridinethione salt. Such anti-dandruff particles should be physically and chemically compatible with the constituents of the composition and should not otherwise excessively compromise product stability, aesthetics, or performance.

0068Pyridinethione microparticles are suitable microparticle antidandruff active substances used in the compositions of the present invention. In certain embodiments, the antidandruff active substance is a 1-hydroxy-2-pyridinethione salt, which is in the form of fine particles. In certain embodiments, the concentration of pyridinethione antidandruff particles is from about 0.01% to about 5% by weight, or from about 0.1% to about 3% by weight, or from about 0.1% to about 2% by weight. Is the range of. In certain embodiments, the pyridinethione salt is a heavy metal such as zinc, tin, cadmium, magnesium, aluminum and zirconium, generally zinc, typically 1-hydroxy-2-pyridinethione (also known as "zinc pyridinethione" or It is formed from a zinc salt of "ZPT"), generally a 1-hydroxy-2-pyridinethione salt, in the form of fine platelets. In certain embodiments, the 1-hydroxy-2-pyridinethione salt in the form of platelet microparticles has an average particle size of up to about 20 micrometers, or up to about 5 micrometers, or up to about 2.5 micrometers. Salts formed from other cations such as sodium may be suitable as well. Pyridinethione antidandruff active substances are, for example, U.S. Pat. Nos. 2,809,971, 3,236,733, 3,753,196, 3,761,418, 4,345,080, 4,323,683. It is described in the specification, the specification No. 4,379,753, and the specification No. 4,470,982.

0069In certain embodiments, the composition further comprises one or more antifungal and / or antibacterial active agents, in addition to the antidandruff active agent selected from the polyvalent metal salts of pyrithione. In certain embodiments, the antibacterial active agents are coal tar, sulfur, fcharcoal, whitfield ointment, casterani ointment, aluminum chloride, gentiana violet, octopirox.<u style="single">(Registered trademark)</u>(Pyroctone olamine), cyclopyrox olamine, undesicylene acid and its metal salts, potassium permanganate, selenium sulfide, sodium thiosulfate, propylene glycol, bitter orange oil, urea preparation, glyceofrubin, 8-hydroxyquinoline shiroki Noll, thiobendazole, thiocarbamate, haloprodine, polyene, hydroxypyridone, morpholine, benzylamine, allylamine (terbinafine, etc.), teawood oil, clove leaf oil, coriander, palmarosa, velverin, thyme red, cinnamon oil, coconut aldehyde , Citroneric acid, hinokitol, ichthiol pail, Sensiva SC-50, Elestab HP-100, azelaic acid, lyticase, iodopropynylbutylcarbamate (IPBC), isothiazalinone such as octylisothiazalinone , And azoles, and mixtures thereof. In certain embodiments, the antibacterial agent is selected from the group consisting of itraconazole, ketoconazole, selenium sulfide, coal tar, and mixtures thereof.

0070Azole antibacterial substances are benzoimidazole, benzothiazole, bihonazole, butaconazole nitrate, cleanbazole, clotrimazole, croconazole, everconazole, econazole, erviol, fenticonazole, fluconazole, fluconazole, isoconazole, ketoconazole, lanoconazole, metronazole, miconazole. , Neticonazole, omoconazole, oxyconazole nitrate, sertaconazole, sulconazole nitrate, thioconazole, thiazole, and imidazole selected from the group consisting of mixtures thereof, or azole antibacterial agents are telconazole, itraconazole, and theirs. A triazole selected from the group consisting of mixtures. When present in the composition, the azole antibacterial active substance is about 0.01% to about 5% by weight, or about 0.1% to about 3% by weight, or about 0.3% to about 2% by weight of the entire composition. Included in% by weight. In certain embodiments, the azole antibacterial active agent is ketoconazole. In certain embodiments, the only antibacterial active substance is ketoconazole.

0071The present invention may also include a combination of antibacterial active substances. In certain embodiments, the combination of antibacterial active agents is Octopirox.<u style="single">(Registered trademark)</u>And zinc pyrithione, pine tar and sulfur, salicylic acid and zinc pyrithione, salicylic acid and elviol, zinc pyrithione and elviol, zinc pyrithione and crimbasol, octopirox<u style="single">(Registered trademark)</u>And Crimbasol, salicylic acid and Octopirox<u style="single">(Registered trademark)</u>, As well as a group of combinations consisting of mixtures thereof.

0072In certain embodiments, the composition comprises an effective amount of zinc-containing layered material. In certain embodiments, the composition contains about 0.001% to about 10% by weight, or about 0.01% to about 7% by weight, or about 0.1% to about 5% by weight of zinc in the total composition. Includes layered material.

0073The zinc-containing layered material can have crystal growth that occurs primarily in two dimensions. It is customary for the layered structure not only to have all the atoms incorporated into a well-defined layer, but also to have ions or molecules between the layers, called gallery ions (. AFWells "Structural Inorganic Chemistry" Clarendon Press, 1975). The zinc-containing layered material (ZLM) may have zinc incorporated into the layer and / or may be a component of gallery ions. The following types of ZLM represent relatively common examples of the general category, but are not intended to limit a wider range of substances that fit this definition.

0074Many ZLMs are naturally produced as minerals. In certain embodiments, ZLM is made from zinc hydroxide soil (zinc hydroxide), basic zinc carbonate, aurichalcite (zinc hydroxide copper), zinc peacock stone (zinc carbonate), and mixtures thereof. Selected from the group consisting of. Related minerals containing zinc may also be included in the composition. Natural ZLM can also be generated, in which the seeds of the anionic layer, such as clay-type minerals (eg, phyllosilicates), contain ion-exchanged zinc galleries ions. All of these natural materials can be obtained synthetically, produced directly in the composition, or produced in the manufacturing process.

0075Another common category of ZLM that is usually synthetic but not always synthetic is layered compound hydroxides. In certain embodiments, ZLM has the formula [M²⁺_1-xM³⁺_x(OH)₂]^{x +}A^m-_{x / m} NH₂It is a layered compound hydroxide compatible with O and is a divalent ion (M).²⁺) Is a zinc ion (Crepaldi, EL, Pava, PC, Tronto, J, Valim, JB J. Colloid Interfac. Sci. 2002,248,429 ~ 42).

0076There are other types of ZLM that can be prepared, called hydroxy double salts (H. Morioka, H., H. Tagaya, H., M. Karasu). , M), J. Kadokawa (J), K. Chiba (Chiba, K), K Inorg. Chem. 1999, 38, 4211 ~ 6). In certain embodiments, ZLM has the formula [M²⁺_1-xM²⁺_{1 + x}(OH)_{3 (1-y)}]⁺ A^n-_{(1 = 3y) / n} NH₂A hydroxy double salt compatible with O and two metal ions (M)²⁺) May be the same or different. If they are identical and represented by zinc, the formula is [Zn_{1 + x}(OH)₂]^{2x +} 2x A^- NH₂Simplified to. This latter formula represents substances such as zinc chloride and zinc nitrate (when x = 0.4). In certain embodiments, the ZLM is zinc chloride and / or zinc nitrate. Replacing the monovalent anion with a divalent anion, these are also associated with hydrozincite. These materials can also be produced directly in the composition or in the manufacturing process.

0077In certain embodiments, the composition comprises basic zinc carbonate. Commercial sources of basic zinc carbonate include Zinc Carbonate Basic (Cater Chemicals; Bensenville, Illinois, USA), Zinc Carbonate (Shepherd Chemicals); Zinc Carbonate (Norwood, Ohio, USA), Zinc Carbonate (CPS Union Corp.; New York, New York, USA), Zinc Carbonate (Elementis Pigments, Durham, UK), and Zinc Carbonate AC (Bruggemann) Chemical); Newtown Square, Pennsylvania, USA). Basic zinc carbonate, sometimes commercially referred to as "zinc carbonate" or "zinc monocarbonate base" or "hydroxyzinc carbonate", is a type of synthesis consisting of substances similar to naturally occurring zinc monocarbonate. is there. The ideal stoichiometry is Zn₅(OH)₆(CO₃)₂Although represented by, the actual stoichiometric ratio can vary slightly and other impurities may be incorporated into the crystal lattice.

0078In embodiments with a zinc-containing layered material and a pyrithion or a polyvalent metal salt of pyrithion, the ratio of the zinc-containing layered material to the polyvalent metal salt of pyrithion or pyrithion is from about 5: 100 to about 10: 1, or about. 2: 10 to about 5: 1, or about 1: 2 to about 3: 1.

0079Adhesion of antidandruff actives on the scalp is at least about 1 microgram / cm²Is. Adhesion of the anti-dandruff active substance on the scalp is important, considering that the anti-dandruff active substance reaches the scalp and can exert its action reliably there. In certain embodiments, adhesion of the antidandruff active substance onto the scalp is at least about 1.5 micrograms / cm.², Or at least about 2.5 micrograms / cm², Or at least about 3 micrograms / cm², Or at least about 4 micrograms / cm², Or at least about 6 micrograms / cm², Or at least about 7 micrograms / cm², Or at least about 8 micrograms / cm², Or at least about 8 micrograms / cm², Or at least about 10 micrograms / cm²Is. Adhesion of the antidandruff active substance onto the scalp is measured by a skilled hairdresser washing an individual's hair with a composition containing the antidandruff active substance (eg, the composition according to the present invention) according to a conventional cleaning protocol. Will be done. The hair is then divided over the area of the scalp so that the open end glass cylinder can be held on the surface, an aliquot of the extraction solution is added and stirred, then the contents of the antidandruff active substance are recovered and conventional as in HPLC. Analyzing and quantifying based on the methodology.

0080In certain embodiments, the attachment of basic zinc carbonate onto the scalp is at least about 1 microgram / cm.²Is.

0081The composition comprises a cosmetically acceptable carrier. In certain embodiments, the carrier is an aqueous carrier. The amount and chemistry of this carrier is selected depending on its compatibility with other constituents and other desired properties of the product. In certain embodiments, the carrier is selected from the group consisting of water and an aqueous solution of a lower alkyl alcohol. In certain embodiments, the carrier is a lower alkyl alcohol in which the monohydric alcohol has 1 to 6 carbons. In certain embodiments, the carrier is ethanol and / or isopropanol. In certain embodiments, the cosmetically acceptable carrier is a cosmetically acceptable aqueous carrier, present at a concentration of about 20% to about 95%, or about 60% to about 85%.

0082The composition comprises a surfactant. The surfactant is included for the purpose of providing cleaning performance to the composition. In certain embodiments, the surfactant is selected from the group consisting of anionic surfactants, amphoteric surfactants, bipolar ion surfactants, cationic surfactants, nonionic surfactants, and mixtures thereof. Will be done. In certain embodiments, the surfactant is an anionic surfactant. In certain embodiments, the composition has a surface activity of about 5% to about 50% by weight, or about 8% to about 30% by weight, or about 10% to about 25% by weight of the total composition. Contains agents.

0083The composition may include a detergency surfactant system. The detergency surfactant system may contain at least one anionic surfactant, optionally an amphoteric surfactant, a bipolar surfactant, a cationic surfactant, a nonionic surfactant. It may contain an activator or a copolymer selected from the group consisting of mixtures thereof. The detergency surfactant system in the composition must be at a sufficient concentration to provide the desired detergency and foaming performance. In certain embodiments, the composition has a detergency of about 5% to about 50% by weight, or about 8% to about 30% by weight, or about 10% to about 25% by weight of the total composition. Includes surfactant system.

0084Concentrations and types of surfactants to maximize the potential of polymer systems when considering performance characteristics such as coacervate formation, wet conditioning performance, dry conditioning performance, and adhesion of conditioning agents onto the hair. It is desirable to optimize. In one embodiment, the detergency surfactant system used in the composition comprises an anionic surfactant having an ethoxylated level and an anionic level, wherein the ethoxylated level is from about 1 to about 10, and the anionic level is It is about 1 to about 10. Combining this type of anionic surfactant with a cationic copolymer and a cationic guar polymer enhances the adhesion of the conditioning agent to the hair and / or skin without compromising cleaning or foaming performance. The optimum ethoxylation level is calculated based on stoichiometry with respect to the structure of the surfactant and is based on the specific M.Wt. Of the surfactant for which the number of moles of ethoxylation is known. Similarly, the anion level can be calculated by measuring the specific M.Wt. Of the detergent and the completion of the anionization reaction.

0085In certain embodiments, the detergency surfactant system comprises an anions selected from the group consisting of sulfates, sulfonates, sulfosuccinates, isethionic acids, carboxylates, phosphates, and phosphonates. Contains at least one anionic surfactant contained. In certain embodiments, the anion is a sulfate.

0086In certain embodiments, the anionic surfactant is an alkyl sulfate or an alkyl ether sulfate. Each of these substances has the formula R⁹OSO₃M and R⁹O (C₂H₄O)_xSO₃Has M and in the formula, R⁹Is an alkyl or alkenyl having about 8 to about 18 carbon atoms, x is an integer with a value of about 1 to about 10, M is a cation such as ammonium, an alkanolamine such as triethanolamine, sodium and potassium. It is a monovalent metal cation such as, or a polyvalent metal cation such as magnesium and calcium. The solubility of the surfactant depends on the specific anionic surfactant and cation selected. In certain embodiments, R in both alkyl sulphate and alkyl ether sulphate⁹Has about 8 to about 18, or about 10 to about 16, or about 12 to about 14 carbon atoms. Typically, alkyl ether sulphates are produced as a condensation product of ethylene oxide with a monohydric alcohol having about 8 to 24 carbon atoms. Alcohol can be derived from synthetic products or fats (eg coconut oil, palm kernel oil, tallow). In certain embodiments, the alcohols are lauryl alcohols and linear alcohols derived from coconut oil or palm kernel oil. The resulting molecular species obtained by reacting such alcohol with ethylene oxide in a molar ratio of about 0 to about 10 mol, or about 2 to about 5 mol, or about 3, eg, having an average of 3 mol of ethylene oxide per mol of alcohol. Sulfate and neutralize the mixture of. In certain embodiments, the alkyl ether sulfate is a group consisting of coconut alkyl triethylene glycol ether sulfate, tallow alkyl triethylene glycol ether sulfate, tallow alkyl hexaoxyethylene sulfate and mixtures thereof, and ammonium salts. Is selected from. In certain embodiments, the alkyl ether sulphate comprises a mixture of the individual compounds, the compounds in which the compounds have an average alkyl chain length of from about 10 to about 16 carbon atoms and an average degree of ethoxylation. It has 1 to about 4 mol of ethylene oxide. Such a mixture is C_12~13Compounds from about 0% to about 20%, C_14~15~16About 60% by weight to about 100% by weight of the compound, C_17~18~19About 0% by weight to about 20% by weight of the compound, about 3% by weight to about 30% by weight of the compound having 0 degree of ethoxylation, and about 45% to about 90% by weight of the compound having about 1 to about 4 degree of ethoxylation. It contains about 10% by weight to about 25% by weight of a compound having a weight% and ethoxylation degree of about 4 to about 8, and about 0.1% by weight to about 15% by weight of a compound having a toxylation degree of more than about 8.

0087In certain embodiments, the anionic surfactants are ammonium lauryl sulfate, ammonium lauryl sulfate, triethylamine lauryl sulfate, triethylamine lauryl sulfate, triethanolamine lauryl sulfate, triethanolamine lauryl sulfate, monoethanolamine lauryl sulfate, monoethanolamine lauryl sulfate. , Sodium lauryl sulfate diethanolamine, sodium lauryl sulfate diethanolamine, sodium lauryl monoglyceryl sulfate, sodium lauryl sulfate, sodium lauryl sulfate, potassium lauryl sulfate, potassium lauryl sulfate, sodium lauryl sarcosinate, sodium lauryl sarcosinate, sodium lauryl sarcosin, cocoyl sarcosin, ammonium cocoyl sulfate, lauryl Consists of a group consisting of ammonium sulfate, sodium cocoyl sulfate, sodium lauryl sulfate, potassium cocoyl sulfate, potassium lauryl sulfate, triethanolamine lauryl sulfate, triethanolamine lauryl sulfate, monoethanolamine cocoyl sulfate, monoethanolamine lauryl sulfate, and mixtures thereof. Can be selected. Potential anions for other anionic surfactants include phosphonates, phosphates, and carboxylates, in addition to the above sulfates, isethionic acids, sulfonates, and sulfosuccinates.

0088The composition and / or the detergency surfactant system is selected from the group consisting of amphoteric surfactants, bipolar surfactants, cationic surfactants, nonionic surfactants, and mixtures thereof. May include activator. The concentration of such a reactant can be from about 0.5% to about 20% by weight, or from about 1% to about 10% by weight of the total composition. In certain embodiments, the composition comprises an amphoteric surfactant, a bipolar surfactant, and a copolymer selected from the group consisting of mixtures thereof. Non-limiting examples of suitable bipolar or amphoteric surfactants are described in US Pat. Nos. 5,104,646 (Bolich Jr. et al) and 5,106,609 (Bolich Jr. et al).

0089Amphoteric surfactants suitable for use in this composition are well known in the art and are widely used as derivatives of aliphatic secondary and tertiary amines in which the aliphatic radical can be linear or branched. The surfactants described include, in which case one of the aliphatic substituents contains about 8 to about 18 carbon atoms and one is carboxy, sulfonate, sulfate, phosphate. , Or an anionic group such as a phosphonate. In certain embodiments, the amphoteric surfactants are sodium cocaminopropionate, sodium cocaminodipropionate, sodium cocoamphoacetate, sodium cocoamphohydroxypropylsulfonate, sodium cocoamphopropionate, sodium cornamphopropionate, laura. Sodium minopropionate, sodium lauroamphoacetate, sodium lauroamphohydroxypropyl sulfonate, sodium lauroamphopropionate, sodium cornamphopropionate, sodium lauriminodipropionate, ammonium cocaminopropionate, ammonium cocaminodipropionate, cocoampho Ammonium acetate, ammonium cocoamphohydroxypropylsulfonate, ammonium cocoamphopropionate, ammonium cornamphopropionate, ammonium lauraminopropionate, ammonium lauroamphoacetate, ammonium lauroanphohydroxypropylsulfonate, ammonium lauroanphopropionate, cornamphopropion Ammonium acid, ammonium lauriminodipropionate, triethanolamine cocaminopropionate, triethanolamine cocaminodipropionate, triethanolamine cocoamphoacetate, triethanolamine cocoamphohydroxypropylsulfonate, triethanolamine cocoamphopropionate , Cornamphopropionic acid triethanolamine, Lauraminopropionic acid triethanolamine, Lauroanphoacetate triethanolamine, Lauroanphohydroxypropyl sulfonate triethanolamine, Lauroan

0090In one embodiment, the amphoteric surfactant is a surfactant according to the following structure:

0091<chemistry num="10"><img id="000011" he="49" wi="128" file="JP5890528B2_D0001.tif" img-format="tif" img-content="drawing" /></chemistry> In the formula, R¹⁰Is a substituted alkyl system containing 9 to 15 carbon atoms, an unsubstituted alkyl system containing 9 to 15 carbon atoms, a linear alkyl system containing 9 to 15 carbon atoms, and 9 to 15 carbon atoms. It is a C-bond monovalent substituent selected from the group consisting of a branched alkyl system containing 9 to 15 carbon atoms and an unsaturated alkyl system containing 9 to 15 carbon atoms.¹¹, R¹², And R¹³Are independently selected from the group consisting of a C-bonded divalent linear alkyl system containing 1 to 3 carbon atoms and a C-bonded divalent branched chain alkyl system containing 1 to 3 carbon atoms. M⁺Is a monovalent counterion selected from the group consisting of sodium, ammonium and protonated triethanolamine. In certain embodiments, the amphoteric surfactants are sodium cocoamphoacetate, sodium cocoamphoaacetate, sodium lauroamphoacetate, sodium lauroamphodiacetate, ammonium lauroanphoacetate, ammonium cocoamphoacetate, triethanolamine lauroamphoacetate, triethanolamine cocoamphoacetate, And a mixture of these.

0092In certain embodiments, the composition comprises a bipolar surfactant. This bipolar surfactant is a derivative of an aliphatic quaternary ammonium, phosphonium, and sulfonium compound, the aliphatic radical is a straight chain or a branched chain, and one of the aliphatic substituents is about 8 to about 18. It contains a number of carbon atoms, one containing anionic groups such as carboxy, sulfonates, sulfates, phosphates or phosphonates. In certain embodiments, the bipolar surfactants are cocamidoethylbetaine, cocamidopropylamine oxide, cocamidopropylbetaine, cocamidopropyldimethylaminohydroxypropyl hydrolyzed collagen, cocamidopropyldimonium hydroxypropyl hydrolyzed collagen. , Cocamidopropyl hydroxysultaine, cocobetaine amide amphopropionic acid, coco-betaine, coco-hydroxysultaine, coco / oleamide propyl betaine, coco-sultaine, lauramidopropyl betaine, lauryl betaine, lauryl hydroxysultaine, lauryl It is selected from the group consisting of sultaine and mixtures thereof. In certain embodiments, the bipolar surfactant is lauryl hydroxysultaine, cocamidopropyl hydroxysultaine, coco-betaine, coco-hydroxysultaine, coco-sultaine, lauryl betaine, lauryl sultine, and mixtures thereof. Selected from the group consisting of.

0093In certain embodiments, the copolymer is selected from bipolar surfactants, amphoteric surfactants, nonionic surfactants, and mixtures thereof. In certain embodiments, the surfactant is an anionic surfactant, the composition further comprises a copolymer, which is a bipolar surfactant, an amphoteric surfactant, a nonionic surfactant. It is selected from the group consisting of agents and mixtures thereof. In certain embodiments, the reactants are cocamide, cocamide methyl MEA, cocamide DEA, cocamide MEA, cocamide MIPA, lauramide DEA, lauramide MEA, lauramide MIPA, myristamide DEA, myristamide MEA, PEG-20 cocamide MEA, PEG-2 cocamide. , PEG-3 Cocamide, PEG-4 Cocamide, PEG-5 Cocamide, PEG-6 Cocamide, PEG-7 Cocamide, PEG-3 Lauramide, PEG-5 Lauramide, PEG-3 Oleamide, PPG-2 Cocamide, PPG-2 Hydroxy A nonionic surfactant selected from the group consisting of ethyl cocamide and mixtures thereof. In certain embodiments, the auxiliary surfactant is a bipolar surfactant, the bipolar surfactant being lauryl hydroxysultaine, cocamidopropyl hydroxysultaine, coco-betaine, coco-hydroxysultaine, coco. -Selected from the group consisting of sultaine, lauryl betaine, lauryl sultaine, and mixtures thereof.

0094According to embodiments of the invention, the composition further comprises an insoluble polysiloxane. Surprisingly, with silicone emulsions of insoluble polysiloxanes (eg, polydimethylsiloxanes), cationic guar polymers, and / or acrylamide monomers, which have a total cyclic polysiloxane content of less than 2.5% by weight based on the total weight of all polysiloxanes. Formulation of personal care compositions in combination with cationic copolymers with cationic monomers improves the adhesion of conditioning polymers and insoluble polysiloxanes to the skin and hair, as well as consumption for hair conditioning and hair feel. It has been found that hair can be improved with little or no rejection of the person.

0095Without being bound by any particular theory, insoluble polysiloxane emulsions can improve consumer acceptance of hair conditioning and hair feel when cyclic polysiloxane concentrations fall below the above thresholds, and nevertheless the scalp. It is considered to be excellent in adhesion to the top. Cyclic polysiloxane interrupts the formation of higher order surfactant micelles and, as a result, the amount of salt added to the composition needs to be increased in order to obtain acceptable rheological parameters for the composition. It is thought that it will occur. However, an increase in viscosity is observed to induce an increase in viscosity, which can also increase the floc size of coacervates. Increasing the flock size, for example, allows larger flock to be trapped in the hair, which can have a negative effect on adhesion on the scalp. By mixing the anionic surfactants, cationic conditioning polymers and silicone emulsions specified herein, surprisingly, the molecular weight of the cationic guar is reduced and the cationic copolymers and silicones in a single composition. It has been found that while the increased adhesion of the consumer can obtain both desired benefits, it is still maintained in the state desired by the consumer. Conveniently, this combination with surfactants, polymers and silicones helps to attach active substances such as anti-dandruff active substances.

0096More specifically, it is believed that the insoluble polysiloxane of the desired particle size (&lt;10 micrometers) in the embodiments of the present invention can be incorporated into the coacervate microstructure and delivered to the hair and scalp. The entry of insoluble polysiloxane species into the coacervate microstructure results in looser bond of the structure. This can be characteristic of high adhesion systems such as cationic guar / synthetic copolymer systems. Slow binding of coacervate microstructures can be characterized by a reduction in complex coacervate rheology (CCR).

0097Due to the influence of the silicone emulsion, the desired reduction in coacervate floc size and rheology will be further achieved. Generally, silicone microemulsions and nanoemulsions contain varying amounts of residual cyclic polysiloxane. For example, dimethiconol may contain significant amounts of cyclic polysiloxanes, such as octamethylcyclotetrasiloxane and decamethylcyclotetrasiloxane. Cyclic polysiloxane is significant for anionic surfactant-based compositions such as shampoos by interrupting the formation of higher-order surfactant micelles, which are crucial for achieving consumer-accepted constituent viscosity targets. May have a significant effect. If higher micelle formation is interrupted, as a result, higher concentrations of NaCl will be added to the personal care composition for the purpose of compensating for the decrease in viscosity. However, it has been empirically clarified that increasing the salt concentration increases the coacervate particle size, resulting in unfavorable cosmetic results. Therefore, by including the cyclic polysiloxane having the following concentration in the silicone emulsion of polysiloxane, the adhesion and quality can be unexpectedly improved, and at the same time, the hair feel can be improved.

0098The characteristics of the composition according to the first aspect, the other aspect, and other related components are described in detail herein thereafter. All ingredients described herein should be physically and chemically compatible with the essential ingredients described herein, otherwise excessively product stability, aesthetics or It must not impair performance.

0099According to one embodiment of the present invention, there is provided a personal care composition comprising a) an anionic surfactant, b) a cationic conditioning polymer, and c) a silicone emulsion containing an insoluble polysiloxane.

0100A. Silicone emulsion Silicone emulsions suitable for use in embodiments of the present invention include emulsions of insoluble polysiloxanes prepared as described in US Pat. No. 4,476,282 and US Patent Application Publication No. 2007/0276087. Therefore, the insoluble polysiloxane referred to herein to meet the object of the present invention, such as α, ω hydroxy-terminated polysiloxane, or α, ω alkoxy-terminated polysiloxane, is about 50,000 to about 500,000. Examples thereof include polysiloxane having a molecular weight in the range of g / mol. As used herein, "insoluble polysiloxane" means that the water solubility of the polysiloxane is less than 0.05% by weight. In another embodiment, the water solubility of the polysiloxane is less than 0.02% by weight, or less than 0.01% by weight, or less than 0.001% by weight. According to certain embodiments, the insoluble polysiloxane is present in the personal care composition in an amount in the range of about 0.1% to about 3% by weight based on the total weight of the composition. For example, the insoluble polysiloxane ranges from about 0.2% to about 2.5% by weight, or about 0.4% to about 2.0% by weight, or about 0.5% to about 1.5% by weight based on the total weight of the composition. Can be present in the amount within.

0101According to one aspect of the silicone emulsion, the insoluble polysiloxane used herein comprises an α, ω hydroxy or alkoxy-terminated polysiloxane having the following general formula I: R¹⁵-[O-Si (R)¹⁴)₂]_n-OR¹⁵ In the formula, "n" is an integer, R¹⁴Is a substituted or unsubstituted C₁~ C₁₀Alkyl or aryl, R¹⁵Is hydrogen or substituted or unsubstituted C₁~ C₁₀It is alkyl or aryl. R¹⁴And R¹⁵Non-limiting examples of alkyl groups include, for example, methyl, ethyl, n-propyl, isopropyl, n-butyl, isobutyl, tert-butyl, n-pentyl, isopentyl, neopentyl, tertpentyl, hexyl, eg n-hexyl, Heptyl, eg, n-heptyl, octyl, eg, n-octyl, and isooctyl, eg, 2,2,4-trimethylpentyl, nonyl, eg, n-nonyl, decyl, eg, n-decyl, dodecyl, eg, n-decyl, dodecyl, eg, It can be independently selected from n-dodecyl, octadecyl, eg, n-octadecyl, or aryl groups such as phenyl, naphthyl, anthryl, and phenanthryl. In certain embodiments, the insoluble polysiloxane is of the general formula H- [O-Si (R).¹⁴)₂]_nHas -OH.

0102According to another aspect of the silicone emulsion, the insoluble polysiloxane has an average molecular weight in the range of about 50,000 to about 500,000 g / mol. For example, insoluble polysiloxanes can have an average molecular weight in the range of about 60,000 to about 400,000, about 75,000 to about 300,000, about 100,000 to about 200,000, or an average molecular weight of about 150,000 g / mol.

0103According to another aspect of the silicone emulsion, the general formula:

0104<chemistry num="11"><img id="000012" he="18" wi="128" file="JP5890528B2_D0001.tif" img-format="tif" img-content="drawing" /></chemistry> (In the formula, R¹⁴Is the same as the above definition, m is 4 or 5), and the total content of cyclic polysiloxane is present in the silicone emulsion in an amount less than about 2.5% by weight based on the total weight of the total polysiloxane. .. For example, dimethiconol may contain significant amounts of cyclic polysiloxanes such as octamethylcyclotetrasiloxane (D4) and decamethylcyclotetrasiloxane (D5). In certain embodiments, the amount of D4 is less than about 2.0%, or less than about 1.5%, or less than about 1.0%, or less than about 0.5% relative to the total weight of the total polysiloxane. In certain embodiments, the amount of D5 is less than about 0.5%, or less than about 0.4%, or less than about 0.3%, or less than about 0.2% relative to the total weight of the total polysiloxane.

0105According to yet another aspect of the silicone emulsion, the emulsion has a viscosity of up to about 500,000 cPs. For example, the viscosity can be in the range of about 75,000 to about 300,000, about 100,000 to about 200,000, or about 150,000 cPs.

0106According to yet another aspect of the silicone emulsion, the insoluble polysiloxane has an average particle size in the range of about 30 nm to about 10 micrometers. The average particle size can be, for example, in the range of about 40 nm to about 5 micrometers, about 50 nm to about 1 micrometer, about 75 nm to about 500 nm, or about 100 nm.

0107The average molecular weight of the insoluble polysiloxane, the viscosity of the silicone emulsion, and the particle size of the insoluble polysiloxane-containing material are commonly used by those skilled in the art, such as Smith, ALThe Analytical Chemistry of Silicones, John Wiley &amp; Sons, Inc .: New. Obtained by the method disclosed in York, 1991.

0108According to another aspect of the silicone emulsion, the emulsion further comprises an anionic surfactant involved in the delivery of a high internal phase viscosity emulsion having a particle size in the range of about 30 nm to about 10 micrometers. The anionic surfactant is selected from organic sulfonic acids. Alkyrylaryl sulfonic acid, alkylaryl polyoxyethylene sulfonic acid, alkyl sulfonic acid, and alkyl polyoxyethylene sulfonic acid are very common as the sulfonic acids used in this process. The general formula for sulfonic acid is as follows. R¹⁶C₆H₄SO₃H (II) R¹⁶C₆H₄O (C₂H₄O)_mSO₃H (III) R¹⁶SO₃H (IV) R¹⁶O (C₂H₄O)_mSO₃H (IV) In the formula, R¹⁶May be different and is a monovalent hydrocarbon group having at least 6 carbon atoms. R¹⁶Non-limiting examples of are hexyl, octyl, decyl, dodecyl, cetyl, stearyl, myristyl, and oleyl. "M" is an integer from 1 to 25. Exemplary anionic surfactants are octylbenzene sulfonic acid, dodecylbenzene sulfonic acid, cetylbenzenesulfonic acid, α-octylsulfonic acid, α-dodecylsulfonic acid, αcetylsulfonic acid, polyoxyethylene octylbenzenesulfonic acid, Includes, but is not limited to, polyoxyethylene dodecylbenzene sulfonic acid, polyoxyethylene cetylbenzene sulfonic acid, polyoxyethylene octyl sulfonic acid, polyoxyethylene dodecyl sulfonic acid, and polyoxyethylene cetyl sulfonic acid. Generally, 1-15% anionic surfactant is used in the emulsion process. For example, when the amount of the anionic surfactant used is 3 to 10%, the optimum result can be obtained.

0109Silicone emulsions may further contain additional emulsifiers in addition to the anionic surfactants, thereby controlling the temperature of emulsification and polymerization and facilitating the production of emulsions more rapidly in a simple manner. Nonionic emulsifiers preferably have a hydrophilic lipophilic balance (HLB) value of 10-19, including polyoxyalkylene alkyl ethers, polyoxyalkylene alkyl phenyl ethers, and polyoxyalkylene sorbitan esters. Is done. Some useful emulsifiers with HLB values of 10-19 include polyethylene glycol octyl ether, polyethylene glycol lauryl ether, polyethylene glycol tridecyl ether, polyethylene glycol cetyl ether, polyethylene glycol stearyl ether, polyethylene glycol nonylphenyl ether, polyethylene. Includes, but is not limited to, glycoldodecylphenyl ether, polyethylene glycol cetylphenyl ether, polyethylene glycol stearylphenyl ether, polyethylene glycol sorbitan monostearate, and polyethylene glycol sorbitan monooleate.

0110According to embodiments of the present invention, the personal care composition may further comprise one or more beneficial agents. Exemplary beneficial agents include particles, colorants, aromatic microcapsules, gel network, and other insoluble skin conditioning agents or hair conditioning agents such as skin silicones, and natural oils such as sunflower oil or castor oil. It is not limited to. In certain embodiments, the beneficial agents are particles; colorants; aromatic microcapsules; gel network; other insoluble skin or hair conditioning agents (eg skin silicone), natural oils (eg sunflower oil or castor oil); And a mixture of these.

0111The composition forms coacervate particles when diluted with water. The percentage of coacervate particles with a floc size greater than about 20 micrometers is about 1% to about 60%. In certain embodiments, the percentage of coacervate particles with a floc size greater than about 20 micrometers is about 1% to about 50%, or about 1% to about 40%, or about 1% to about 30%, or about 5. % ~ About 20%, about 5% ~ about 15%. After diluting the composition with water to a dilution ratio of 1:50, measure the floc size.

0112The Lasentec FBRM method can be used to measure flock size. The composition is placed in a suitable mixing vessel to prepare a diluted solution dissolved in distilled water at a ratio of 1: 9, and mixed at an ambient temperature of 250 rpm for 5 minutes. The environmental distilled water is transferred to the mixing vessel at a rate of 100 g / min using a sliding pump to a final dilution of composition to distilled water of 1:50 parts. After equilibration for 10 minutes, measured at chord length and particles (several seconds) using the Lasentec Focused Beam Reflectance Method (FBRM) [model S400A, available from Mettler Toledo Corp]. Quantify flock size and amount.

0113The viscosity of the coacervate fine particles can be measured by squeezing to obtain the squeezing viscosity. Coacervates can be prepared and isolated for rheological testing as follows. The composition is diluted 1:50 in distilled water, mixed well, centrifuged at 4500 rpm for 30 minutes and then prepared at ambient temperature in an amount that produces at least 3 grams of coacervate pellets. Tilt and discard the supernatant and collect coacervate pellets. A second centrifugation step of 15 minutes at 9100 rpm is required to ensure sample consistency prior to measurement. Remove all remaining supernatant without affecting the coacervate pellets collected at the bottom of the vessel.

0114In the squeeze experiment, the coacervate under test is loaded between two parallel plates with radius R on a conventional rheometer (eg, 25 mm parallel plates on the TA AR2000) equilibrated at 25 ° C. .. Prior to the start of the test, add enough coacervate to completely fill the 1000 micrometer gap and truncate all excess material. Relieve sample load stress for 1 minute. As the gap shrinks, the upper plate descends at a constant velocity. During this step, the normal force applied by the sample to the lower plate is measured with a rheometer. A typical linear velocity used for squeezing experiments is 10 or 100 micrometers / sec. The 1000 micrometer gap is reduced until the final gap reaches 100 micrometers or the normal force reaches the maximum instrument tolerance.

0115The measured forces F and gap h are further analyzed to determine the conventional viscosity vs. shear rate format. Squeezing analysis between Newtonian parallel plates and various non-Newtonian materials is published in the literature (J. of Non-Newtonian Fluid Mechanics, 132 (2005) 1-27). The power law model is chosen when explaining coacervates because it is best suited to explain viscosity behavior in the non-linear region. From the equations corresponding to the forces, we quantify the power law parameter K, power law consistency, and power law exponent n as a function of constant region, constant linear velocity, and gap under no-slip squeeze (J. of Non-Newtonian Fluid Mechanics, 132 (2005) 1-27). First, the natural logarithms of both sides of the equation are taken to linearize the nonlinear force vs. gap equation. The power law parameters K and n are then determined from the slopes and intercepts that fit the linear region of ln (force) vs. ln (gap) using known constants under experimental conditions. Using these K and n values, the squeezed viscosity η is specified via a power law model.

0116<maths num="1"><img id="000013" he="6" wi="128" file="JP5890528B2_D0001.tif" img-format="tif" img-content="drawing" /></maths> Can be calculated with.

0117<maths num="2"><img id="000014" he="14" wi="128" file="JP5890528B2_D0001.tif" img-format="tif" img-content="drawing" /></maths>

0118Using this relationship, shear rate 100s^-1Quantify the squeezed viscosity with.

0119The composition forms coacervate particles when diluted with water. 100s at 25 ° C using TA AR2000 rheometer^-1The coacervate particles measured in 1) are about 1 Pa · s ~ about 100 Pa · s, or about 1 Pa · s ~ about 80 Pa · s, or about 2 Pa · s ~ about 60 Pa · s, or about 3 Pa · s ~ about 50 Pa · s. , Or about 4 Pa · s ~ about 40 Pa · s, or about 5 Pa · s ~ about 30 Pa · s, or about 10 Pa · s ~ about 20 Pa · s with coacervate viscosity. Pa · s means Pascal seconds. These values relate to the case where the composition is diluted with water to a ratio of about 1:50 (composition: water).

0120According to one embodiment of the method, an average consumer acceptance score of 60 or higher, or 65 or higher, or 70 or higher, or 75 or higher, or 80 or higher, or 85 or higher is achieved on a scale of 1 to 100. The composition is evaluated by a consumer panel of 10 to 400 people, for example 16 to 310 people, for the purpose of obtaining an average consumer acceptance score. Ask panelists to use only this composition as a shampoo for a period of 3 days to 4 weeks. After use, ask panelists to evaluate the compositions with different attributes and their experience of use on a 5-point scale. For numerical analysis, convert the answer to a scale of 100 points and calculate the average consumer acceptance score.

0121An alternative embodiment of the first aspect relates to a method of treating hair, wherein the method (a) A cationic guar polymer having a weight average of less than about 1,000,000 g / mol and a charge density of about 0.1 meq / g to about 2.5 meq / g. (b) With the copolymer which is a cationic copolymer of an acrylamide monomer and a cationic monomer and has a charge density of about 1.0 meq / g to about 3.0 meq / g. (c) Anti-dandruff active substance and (d) Acceptable carriers for cosmetics, (e) Including a step of applying a composition containing a surfactant to hair. The weight ratio of (a): (b) is about 1000: 1 to about 3.5: 1. And the total of (a) + (b) is about 0.0001% by weight to about 0.7% by weight of the whole composition.

0122In an embodiment according to this alternative embodiment, the method is a step of diluting the composition with water, i.e., diluting with water so that the composition: water weight ratio is about 1:50 (composition: water). Further includes steps. In some embodiments, the composition is diluted with water to a ratio of 1:50 to form coacervate particles. 100s at 25 ° C using TA AR2000 rheometer^-1The coacervate particles measured in 1 have a squeeze viscosity of about 1 cP to about 100 cP, and the percentage of coacervate fine particles having a floc size of more than about 20 micrometers is about 1% to about 60%, and the antidandruff active substance is on the scalp. Adhesion to at least about 1 microgram / cm²Is. In an embodiment according to this alternative embodiment, the method further comprises the step of rinsing the hair.

0123According to the second aspect, the present invention relates to a hair conditioning composition, which comprises the present composition. (a) A cationic guar polymer having a weight average of less than about 1,000,000 g / mol and a charge density of about 0.1 meq / g to about 2.5 meq / g. (b) With the copolymer which is a cationic copolymer of an acrylamide monomer and a cationic monomer and has a charge density of about 1.0 meq / g to about 3.0 meq / g. (c) Anti-dandruff active substance and (d) Acceptable carriers for cosmetics, (e) Including a step of applying a composition containing a surfactant to hair. The weight ratio of (a): (b) is about 1000: 1 to about 3.5: 1. And the total of (a) + (b) is about 0.0001% by weight to about 0.7% by weight of the whole composition.

0124The details of the composition described with respect to the first aspect also apply mutatis mutandis to the composition of the second aspect.

0125In one embodiment, Brookfield R / S Plus Rheometer is used at 26.6 ° C for 2s.^-1The composition measured in 1 has a viscosity of 4,000 cP to 20,000 cP, or about 6,000 cP to about 12,000 cP, or about 8,000 cP to about 11,000 cP.

0126In certain embodiments, the composition has the ability to form coacervate particles when diluted 1:50 with water, using a TA AR2000 rheometer, 100 s at 25 ° C.^-1The coacervate particles measured in 1 have a squeeze viscosity of about 1 cP to about 100 cP, and the percentage of coacervate fine particles over about 20 micrometers has a floc size of about 1% to about 60%, the scalp of an antidandruff active substance. Adhesion on top is at least about 1 microgram / cm²Is. The coacervate details and consumer acceptance described with respect to the first aspect also apply mutatis mutandis to the composition of the second aspect.

0127A third aspect relates to a method of using the composition according to the second aspect for hair treatment. In certain embodiments, the purpose of use is to achieve a better hair feel and / or a reduction in dandruff. The details of the composition described with respect to the first aspect also apply mutatis mutandis to the composition of the third aspect.

0128The fourth aspect of the kit is (a) Application instructions including the method according to the first aspect, (b) The composition and the kit comprising.

0129In certain embodiments, the composition of the kit is the composition according to the second aspect.

0130The details of the composition described with respect to the first aspect also apply mutatis mutandis to the composition of the fourth aspect. The details of the method described with respect to the first aspect also apply mutatis mutandis to the method of the fourth aspect.

<p num="0131"> The following examples exemplify the present invention. The illustrated compositions can be prepared by conventional compounding and mixing techniques. It will be appreciated that other modifications of the invention within the skill of an expert in the field of hair care prescribing may be made without departing from the spirit and scope of the invention. All parts, percentages, and ratios herein are weight-based unless otherwise specified. Some components may be obtained as dilute solutions from sources. Unless otherwise specified, the concentrations described represent weight percentages of the active substance.</p><p num="0132"> Example 1<u style="single">、2</u>, 8 and 9 are examples according to the present invention.<u style="single">3、4、</u>5, 6, 7 and 10 to 11 do not conform to the present invention.</p><p num="0133"><tables num="1"><img id="000015" he="91" wi="158" file="JP5890528B2_D0001.tif" img-format="tif" img-content="drawing" /></tables> Usage Guide:</p><p num="0134"><tables num="2"><img id="000016" he="57" wi="159" file="JP5890528B2_D0001.tif" img-format="tif" img-content="drawing" /></tables></p><p num="0135"> comparison data Experiment I: In Experiment I, the compositions in the table below are compared with respect to the coacervate squeezed viscosity, the floc size of the coacervate particles, the adhesion of the antidandruff active substance on the scalp, and the consumer acceptance score. Compositions 1, 3-8, and 10 are quoted from the table in the section of Examples above. The results are shown in the table below.</p><p num="0136"><tables num="3"><img id="000017" he="59" wi="159" file="JP5890528B2_D0001.tif" img-format="tif" img-content="drawing" /></tables> Usage Guide:¹= Trimonium guar hydroxypropyl chloride (charge density of 0.8 meq / g and M.Wt. of 500,000 g / mol);²= Rhodia PQ-76 (1.6 meq / g charge density and 1,000,000 g / mol M.Wt.).</p><p num="0137"><tables num="4"><img id="000018" he="76" wi="159" file="JP5890528B2_D0001.tif" img-format="tif" img-content="drawing" /></tables> Usage Guide:^#= Quote from the table in the example section above;¹= Guar hydroxypropyltrimonium chloride (charge density of 0.7 meq / g, M.Wt. of 425,000 g / mol);²= Rhodia PQ-76 (1.6meq / g charge density, 1,000,000g / mol M.Wt.);³= Ashland formulation, ie, guar hydroxypropyl trimonium (500,000 g / mol M.Wt., 1.1 meq / g charge density) AM / APTAC (1,100,000 g / mol M.Wt., 1.8 meq) / G charge density) at 95: 5.</p><p num="0138"> The compositions detailed in the Examples section above contain guarhydroxypropyltrimonium chloride and PQ-76 in various proportions. Experiment I shows the trade-off that exists between better consumer tactile scores and increased antidandruff adhesion on the scalp. Composition X is a control for guar alone.</p><p num="0139"> The values (a) + (b) according to the present invention correlate with respect to consumer acceptance. This correlation can be confirmed when the composition 8 and the composition 10 are compared. The composition 10 has a large amount of adhesion, and as a result, the average consumer acceptance score is out of the acceptable range. On the other hand, the composition 8 has a large amount of adhesion and a good consumer acceptance score. The only difference between composition 8 and composition 10 is the total amount of cationic guar polymer and cationic copolymer, i.e. (a) + (b) values. Adhesion of antidandruff agents is similar in both Composition 8 and Composition 10. Composition 8 has a lower percentage of coacervate particles with a floc size greater than 20 micrometers compared to composition 10. This percentage is due to the floc size, resulting in a good consumer acceptance score for composition 8 versus a poor consumer acceptance score for composition 10.</p><p num="0140"> Experiment II: The following compositions A to H are prepared. Compositions A through H are based on a chassis containing 12.5% (SLE1S); 1.5% sodium lauryl sulfate (SLS); 1.5% cocamidopropyl betaine (CAPB); 1% dimethiconol emulsion from Wacker. The compositions B and C conform to the present invention. The compositions A, D, E, F, G and H do not conform to the present invention. Composition A represents Example 1 of European Patent Application Publication No. 1080714A2, particularly relating to cationic guar polymers and cationic copolymers. The chassis is similar to the other components of Example 1 of European Patent Application Publication No. 1080714A2. The US equivalent of European Patent Application Publication No. 1080714A2 is US Patent Application Publication No. 2003/0176303. The compositions in the table below are compared for the squeezed viscosity of the coacervate particles, the floc size of the coacervate particles, and the adhesion of the antidandruff active substance onto the scalp. The results are shown in the table.</p><p num="0141"><tables num="5"><img id="000019" he="50" wi="159" file="JP5890528B2_D0001.tif" img-format="tif" img-content="drawing" /></tables> Usage Guide:^*= Acrylamide propyltrimonium chloride / acrylamide copolymer (available from Ciba with a charge density of 4,000,000 g / mol M.Wt. And 4.2 meq / g); § = Jaguar® C-17 above Available from the Rhodia Company, which fits Formula G and has a cationic charge density of about 0.6 meq / g and an M.Wt. Of about 2,200,000 g / mol;¹= Guar hydroxypropyltrimonium chloride (0.7meq / g charge density, 425,000 g / mol M.Wt.);²= Rhodia PQ-76 (1.6meq / g charge density, 1,000,000g / mol M.Wt.);³= Ashland Formulation: Guar Hydroxypropyl Trimonium Chloride (500,000 g / mol M.Wt .; 1.1 meq / g Charge Density) AM / APTAC (1,100,000 g / mol M.Wt .; 1.8 meq / g) The charge density of) is 95: 5.</p><p num="0142"> As demonstrated in Experiment II, the compositions B and C according to the present invention have good coacervate floc size and squeeze viscosity, resulting in a good consumer acceptance score. The compositions A, D, E, F, G and H are not within the scope of the present invention with respect to the floc size and squeeze viscosity of the coacervate and have low consumer acceptance. Composition A does not conform to the present invention in the molecular weight and charge density of both the cationic guar polymer and the cationic copolymer, and the ratio of (a): (b), resulting in the floc size and squeeze viscosity of the coacervate. Indicates a composition whose properties are outside the scope of the present invention. In composition D, the cationic copolymer of composition A is replaced with a cationic copolymer included within the definition of the cationic copolymer (b) according to the present invention. In composition E, the cationic guar of composition A is replaced with a cationic guar included within the definition of cationic guar (a) according to the present invention. However, in the case of Composition D and Composition E, the coacervate properties with respect to squeeze viscosity and floc size still result in being outside the scope of the present invention. The compositions F, G, and H have a ratio of (a): (b) within the scope of the present invention, but the molecular weight and / or charge density value of the cationic guar polymer or the cationic copolymer is within the scope of the present invention. It proves that it is out of the range. As a result, coacervate characteristics (floc size and squeezing flow viscosity) is outside the range of the present invention Ru. The relationship between coacervate properties (coacervate floc size and squeezed viscosity) and consumer acceptance will be described in the section Figure 1.</p><p num="0143"> Figure 1 FIG. 1 is a graph of coacervate characteristics (coacervate floc size, squeezed viscosity) and consumer acceptance. Axis X: 100s^-1It is the squeezed viscosity (centipores) of the coacervate particles in. Axis Y: Percentage of coacervate particles with a flock size greater than about 20 micrometers. Foam size is related to the consumer acceptance score (larger bubbles mean higher consumer acceptance). The size of the foam decreases as the floc size or squeeze viscosity of the coacervate particles increases. This shows the relationship between consumer acceptance scores and coacervate characteristics. Consumer acceptance of the floc size or squeeze viscosity of coacervate particles decreases when the properties of the cationic polymer change, especially when its ratio and concentration fluctuate outside the scope of the present invention. For example, the ratio of cationic guar polymer: cationic copolymer (that is, (a): (b)) is in the range of "when the weight ratio of (a): (b) is about 1000: 1 to about 3.5: 1". Therefore, the circle filled with dark gray is out of the desired consumer acceptance range. Since the ratio of (a): (b) is below the range of "when the weight ratio of (a): (b) is about 1000: 1 to about 3.5: 1", the composition of the circle filled with black Is outside the scope of the present invention. The light gray circle is beyond the range of "when the sum of (a) + (b) is about 0.0001% to about 0.7%", and thus the desired consumer acceptance. Out of range.</p><p num="0144"> Clause The terms below are part of the description. 1. (a) A cationic guar polymer having a weight average molecular weight of less than about 1,000,000 g / mol and a charge density of about 0.1 meq / g to about 2.5 meq / g. (b) With the copolymer which is a cationic copolymer of an acrylamide monomer and a cationic monomer and has a charge density of about 1.0 meq / g to about 3.0 meq / g. (c) Anti-dandruff active substance and (d) Acceptable carriers for cosmetics, (e) Including a step of applying a composition containing a surfactant to hair. The weight ratio of (a): (b) is about 1000: 1 to about 3.5: 1. A hair conditioning composition in which the sum of (a) + (b) is an amount of about 0.0001% by weight to about 0.7% by weight of the entire composition. 2. Weight average molecular weight of about 150,000 to about 800,000 g / mol, or about 200,000 to about 700,000 g / mol, or about 300,000 to about 700,000 g / mol, or about 400,000 to about 600,000 g / mol of cationic guar polymer. The composition according to clause 1 having. 3. The weight ratio of (a): (b) is about 800: 1 to about 4: 1, or about 500: 1 to about 4: 1, or about 100: 1 to about 5: 1, or about 100: 1 to about 6: 1, or about 50: 1 to about 6.5: 1, or about 50: 1 to about 7: 1, or about 50: 1 to about 8.3: 1, or about 50: 1 to about 16.7: 1. The composition according to Clause 1 or 2. 4. About 1.1meq / g ~ about 2.5meq / g, or about 1.1meq / g ~ about 2.3meq / g, or about 1.2meq / g ~ about 2.2meq / g, or about 1.2meq / g ~ about 2.1meq The charge density of a cationic copolymer of / g, or about 1.3meq / g to about 2.0meq / g, or about 1.3meq / g to about 1.9meq / g, as described in any one of Articles 1-3. Composition. 5. Basic zinc carbonate, zinc carbonate hydroxide, zinc hydroxide soil, zinc hydroxide copper carbonate, zinc hydroxide ore, zinc carbonate copper hydroxide, zinc peacock stone, zinc ion-containing phyllosilicate, layered compound hydroxide, hydroxy The composition according to any one of Articles 1 to 4, further comprising a zinc-containing layered material selected from the group consisting of a compound salt and a mixture thereof. 6. Adhesion of basic zinc carbonate to the scalp is at least about 1 microgram / cm²The composition according to any one of Articles 1 to 5. 7. The cosmetically acceptable carrier is any of Articles 1-6, which is a cosmetically acceptable aqueous carrier and is present at a concentration of about 20% to about 95%, or about 60% to about 85%. The composition according to item 1. 8. The sum of (a) + (b) is about 0.01% to about 0.7% by weight, or about 0.1% to about 0.5% by weight, or about 0.1% to about 0.4% by weight, of the whole composition. Alternatively, the composition according to any one of Articles 1 to 7, which is about 0.2% by weight to about 0.3% by weight. 9. The composition contains the cationic guar polymer (a) in an amount of about 0.01% to about 0.7% by weight, or about 0.04% to about 0.55% by weight, or about 0.08% to about 0.5% by weight of the entire composition. %, Or about 0.16% to about 0.5%, or about 0.2% to about 0.5%, or about 0.3% to about 0.5%, or about 0.4% to about 0.5%, Clause 1 ~ The composition according to any one of 8. 10. The composition comprises about 0.001% to about 0.1% by weight, or about 0.01% to about 0.1% by weight, about 0.02% by weight to about 0.1% by weight of the cationic copolymer (b) of the whole composition. The composition according to any one of Articles 1 to 9, which comprises. 11. The composition is 2s at 26.6 ° C using a Brookfield R / S Plus rheometer.^-1The composition according to any one of Articles 1 to 10, which has a viscosity of 4,000 cP to 20,000 cP when measured in. 12. The composition according to any one of Articles 1 to 11, wherein the surfactant is an anionic surfactant. 13. Cationic monomers are dimethylaminoethyl (meth) acrylate, dimethylaminopropyl (meth) acrylate, diterthiobutylaminoethyl (meth) acrylate, dimethylaminomethyl (meth) acrylamide, dimethylaminopropyl (meth) acrylamide, ethylene. Imine, vinylamine, 2-vinylpyridine, 4-vinylpyridine, trimethylammonium ethyl chloride (meth) acrylate, trimethylammonium ethyl (meth) acrylate methyl sulfate, benzyldimethylammonium ethyl chloride (meth) acrylate, 4-benzoylbenzyldimethyl chloride Clause 1-12, selected from the group consisting of ammonium ethyl acrylate, trimethylammonium ethyl chloride (meth) acrylamide, trimethylammonium propyl (meth) acrylamide chloride, vinyl benzyltrimethylammonium chloride, diallyldimethylammonium chloride, and mixtures thereof. The composition according to any one item. 14. Use of the composition according to any one of Clauses 1 to 11 for the purpose of treating hair. 15. Use as described in Clause 12 for the purpose of achieving improved hair feel. 16. A method of treating hair, which comprises applying the composition according to any one of Articles 1 to 12 to the hair.</p><p num="0145"> The dimensions and values disclosed herein should not be understood to be strictly limited to the exact numbers given. Rather, unless otherwise stated, each such dimension shall mean both the stated value and the functionally equivalent range around that value. For example, the dimension disclosed as "40 mm" is intended to mean "about 40 mm".</p><p num="0146"> All references cited herein, including any cross-references or related patents or applications, are incorporated herein by reference in their entirety, unless expressly excluded or otherwise limited. Neither citation of any document acknowledges that such document is prior art for all inventions disclosed or claimed in the present application, and such document may be used alone or in all other references. It is not acceptable to refer to, teach, suggest or disclose any of these inventions in any combination with. In addition, in this document, if any meaning or definition of a term conflicts with any meaning or definition of a similar term in a document incorporated for reference, the meaning assigned to the term in this document. Or shall comply with the definition.</p><p num="0147"> Although specific embodiments of the present invention have been exemplified and described, it will be apparent to those skilled in the art that various other modifications and modifications can be made without departing from the spirit and scope of the invention. Therefore, all such changes and modifications within the scope of the present invention shall be treated within the scope of the appended claims.</p>