HUP0202757A2

Heteropolycyclic compounds, pharmaceutical compositions containing them and their use as metabotropic glutamate receptor antagonists

Abstract

The invention relates to metabotropic glutamate receptor antagonist compounds that can be used to treat neurological and psychiatric diseases and disorders. In the compounds of formula (II) according to the invention, X, Y and Z are independently a nitrogen, oxygen, sulfur or carbon atom or a carbonyl group, Ar1 and Ar2 are independently an optionally substituted heterocyclic or condensed heterocyclic group chosen from among nitrogen, oxygen and sulfur atoms Contains 1-4 heteroatoms, or a substituted aromatic group selected from the following group: phenyl, benzyl, 1-naphthyl, 2-naphthyl, fluorenyl, anthrenyl, indenyl, phenanthrenyl, benzonaphthenyl. HE

HUP0202757A2, drawing sheet 1
Sheet 1 of 6

Term

No projected expiry on record.

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