Polypeptides

NATURAL APPEARING G-CSF DERIVATIVES ARE DESCRIBED AND HAVE AT LEAST ONE OF THE BIOLOGICAL PROPERTIES OF THE G-CSF OF NATURAL APPEARANCE, AND A MINIMUM SOLUTION STABILITY OF 35% IN 5 MG / ML, IN WHICH THE DERIVATIVE HAS AT LEAST CYS ELEVATED 17 OF THE ORIGINAL SEQUENCE REPLACED BY A WASTE TO BE ELEVATED 17 AND ASP ELEVATED 27 OF THE ORIGINAL SEQUENCE REPLACED BY A WASTE TO BE ELEVATED 27. NUCLEOTIDE SEQUENCES CODING PART OR ALL OF THE AMINO ACID SEQUENCE OF THE DERIVATIVES OF THE INVENTION MAY BE INCORPORATED IN VASIC PLASMIDS OR VIRALS THAT REPRODUCE SELF-EMPLOYED APPLICATORS TO TRANSFORM OR TRANSFER CUEULAR RECEIVING CELLS IN CULTIVATION.