Nova Patents
EP4372000A3

Masked il12 protein

Abstract

Disclosed herein are masked IL12 proteins that can be activated both in vitro and in vivo. Surprisingly, a small, bioorthogonal group is sufficient to deactivate or mask the IL12 protein, which can thereafter be activated by contacting the masked IL12 protein with the bioorthogonal reactive partner of the Trigger joining the IL12 protein to the mask (either a dienophile or a diene). The invention also relates to methods for using and preparing said masked IL12 proteins.

Term

16.4 yearsto projected expiry

Projected expiry 15 February 2043, counted from filing; an application has no term until it is granted.

  1. Priority and filed
  2. Published
  3. Today
  4. Projected expiry

Every citation, both ways

Citations
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WO2018004338A1CitesWorld Intellectual Property Organization (WIPO)Search report
WO2020256544A1CitesWorld Intellectual Property Organization (WIPO)Search report
WO2021189139A1CitesWorld Intellectual Property Organization (WIPO)Search report
WO2021262985A1CitesWorld Intellectual Property Organization (WIPO)Search report