EP2158221A4

Covalent diabodies and uses thereof

Abstract

This record has no abstract on file.

EP2158221A4, drawing sheet 1 — Sheet 1 of 75

Term

1.7 yearsto projected expiry

Projected expiry 13 June 2028, counted from filing; an application has no term until it is granted.

75 sheets

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Every citation, both ways

Citations
Document	Relation	Office	Category	Cited during	Relevant claims
WO0202781A1	Cites	World Intellectual Property Organization (WIPO)	Y	Search report	6-16
WO2006113665A2	Cites	World Intellectual Property Organization (WIPO)	XY	Search report	1-5,17,18
LU DAN ET AL: "A fully human recombinant IgG-like bispecific antibody to both the epidermal growth factor receptor and the insulin-like growth factor receptor for enhanced antitumor activity", JOURNAL OF BIOLOGICAL CHEMISTRY, AMERICAN SOCIETY FOR BIOCHEMISTRY AND MOLECULAR BIOLOGY, INC, US LNKD- DOI:10.1074/JBC.M500815200, vol. 280, no. 20, 20 May 2005 (2005-05-20), pages 19665 - 19672, XP002516978, ISSN: 0021-9258, [retrieved on 20050309]	Non-patent	–	–	Search report	–
LU D ET AL: "Di-diabody: a novel tetravalent bispecific antibody molecule by design", JOURNAL OF IMMUNOLOGICAL METHODS, ELSEVIER SCIENCE PUBLISHERS B.V.,AMSTERDAM, NL LNKD- DOI:10.1016/S0022-1759(03)00251-5, vol. 279, no. 1-2, 1 August 2003 (2003-08-01), pages 219 - 232, XP004455322, ISSN: 0022-1759	Non-patent	–	–	Search report	–
ALT M ET AL: "Novel tetravalent and bispecific IgG-like antibody molecules combining single-chain diabodies with the immunoglobulin gamma1 Fc or CH3 region", FEBS LETTERS, ELSEVIER, AMSTERDAM, NL LNKD- DOI:10.1016/S0014-5793(99)00782-6, vol. 454, no. 1-2, 2 July 1999 (1999-07-02), pages 90 - 94, XP004259932, ISSN: 0014-5793	Non-patent	–	–	Search report	–
WU A M ET AL: "Multimerization of a chimeric anti-CD20 single-chain Fv-Fc fusion protein is mediated through variable domain exchange", PROTEIN ENGINEERING, OXFORD UNIVERSITY PRESS, SURREY, GB LNKD- DOI:10.1093/PROTEIN/14.12.1025, vol. 14, no. 12, 1 January 2001 (2001-01-01), pages 1025 - 1033, XP002982160, ISSN: 0269-2139	Non-patent	–	–	Search report	–
JOHNSON S ET AL: "Effector Cell Recruitment with Novel Fv-based Dual-affinity Re-targeting Protein Leads to Potent Tumor Cytolysis and in Vivo B-cell Depletion", JOURNAL OF MOLECULAR BIOLOGY, LONDON, GB LNKD- DOI:10.1016/J.JMB.2010.04.001, vol. 399, no. 3, 11 June 2010 (2010-06-11), pages 436 - 449, XP027079511, ISSN: 0022-2836, [retrieved on 20100409]	Non-patent	–	–	Search report	–
VERI MARIA-CONCETTA ET AL: "Therapeutic control of B cell activation via recruitment of Fcgamma receptor IIb (CD32B) inhibitory function with a novel bispecific antibody scaffold.", ARTHRITIS AND RHEUMATISM JUL 2010 LNKD- PUBMED:20506263, vol. 62, no. 7, July 2010 (2010-07-01), pages 1933 - 1943, XP002605114, ISSN: 1529-0131	Non-patent	–	–	Search report	–
See also references of WO 2008157379A2	Non-patent	–	–	Search report	–

155 members in 24 offices

This recordMember, by publication date14 more offices are in the list below

Members155

Family members, oldest first
Document	Office	Kind
AU2006236439A1	Australia	A1	2006-10-26
CA2605024A1	Canada	A1	2006-10-26
WO2006113665A2	World Intellectual Property Organization (WIPO)	A2	2006-10-26
US2007004909A1	United States of America	A1	2007-01-04
EP1868650A2	European Patent Office (EPO)	A2	2007-12-26
IL186128A0	Israel	A0	2008-01-20
IL186128D0	Israel	D0	2008-01-20
AU2008265984A1	Australia	A1	2008-12-24
CA2691434A1	Canada	A1	2008-12-24
WO2008157379A2	World Intellectual Property Organization (WIPO)	A2	2008-12-24
WO2008157379A3	World Intellectual Property Organization (WIPO)	A3	2009-02-26
JP2009508466A	Japan	A	2009-03-05
US2009060910A1	United States of America	A1	2009-03-05
WO2006113665A3	World Intellectual Property Organization (WIPO)	A3	2009-04-16
WO2008157379A8	World Intellectual Property Organization (WIPO)	A8	2010-01-14
MX2009013816A	Mexico	A	2010-02-24
EP2158221A2	European Patent Office (EPO)	A2	2010-03-03
KR20100056439A	Republic of Korea	A	2010-05-27
US2010174053A1	United States of America	A1	2010-07-08
AU2009335798A1	Australia	A1	2010-07-15
CA2745460A1	Canada	A1	2010-07-15
WO2010080538A1	World Intellectual Property Organization (WIPO)	A1	2010-07-15
CN101821288A	China	A	2010-09-01
JP2010530756A	Japan	A	2010-09-16
EP1868650A4	European Patent Office (EPO)	A4	2010-12-01
EP2158221A4This record	European Patent Office (EPO)	A4	2010-12-01
MX2011006416A	Mexico	A	2011-07-12
SG172254A1	Singapore	A1	2011-07-28
IL213348A0	Israel	A0	2011-07-31
IL213348D0	Israel	D0	2011-07-31
IL202727A0	Israel	A0	2011-08-01
IL202727D0	Israel	D0	2011-08-01
KR20110104032A	Republic of Korea	A	2011-09-21
EP2376109A1	European Patent Office (EPO)	A1	2011-10-19
CA2807127A1	Canada	A1	2012-02-09
WO2012018687A1	World Intellectual Property Organization (WIPO)	A1	2012-02-09
CN102369021A	China	A	2012-03-07
CL2011001449A1	Chile	A1	2012-04-20
ZA201103699B	South Africa	B	2012-04-25
AU2006236439B2	Australia	B2	2012-05-03
JP2012512894A	Japan	A	2012-06-07
AU2012209050A1	Australia	A1	2012-08-23
JP2012193180A	Japan	A	2012-10-11
RU2011129794A	Russian Federation	A	2013-01-27
AU2011286024A1	Australia	A1	2013-02-21
SG187682A1	Singapore	A1	2013-03-28
EP2376109A4	European Patent Office (EPO)	A4	2013-04-24
MX2013001102A	Mexico	A	2013-05-09
CN103154025A	China	A	2013-06-12
EP2601216A1	European Patent Office (EPO)	A1	2013-06-12
JP2013540696A	Japan	A	2013-11-07
US2013295121A1	United States of America	A1	2013-11-07
IL186128A	Israel	A	2013-11-28
EP2601216A4	European Patent Office (EPO)	A4	2013-12-25
JP2014014363A	Japan	A	2014-01-30
AU2012209050B2	Australia	B2	2014-03-20
AU2008265984B2	Australia	B2	2014-07-17
AU2011286024B2	Australia	B2	2014-08-07
EP2786762A2	European Patent Office (EPO)	A2	2014-10-08
AU2009335798B2	Australia	B2	2014-11-27
AU2014259540A1	Australia	A1	2014-11-27
SG10201407908VA	Singapore	A	2015-01-29
JP5718637B2	Japan	B2	2015-05-13
JP5734201B2	Japan	B2	2015-06-17
CN103154025B	China	B	2015-07-01
EP2786762A3	European Patent Office (EPO)	A3	2015-07-29
JP2015157833A	Japan	A	2015-09-03
BRPI0918122A2	Brazil	A2	2015-11-24
JP5826101B2	Japan	B2	2015-12-02
JP5838021B2	Japan	B2	2015-12-24
KR101599735B1	Republic of Korea	B1	2016-03-07
KR20160027255A	Republic of Korea	A	2016-03-09
US9284375B2	United States of America	B2	2016-03-15
US9296816B2	United States of America	B2	2016-03-29
AU2014259540B2	Australia	B2	2016-06-02
MX339622B	Mexico	B	2016-06-02
US2016159908A1	United States of America	A1	2016-06-09
JP5957424B2	Japan	B2	2016-07-27
IL202727A	Israel	A	2016-07-31
IL224515A	Israel	A	2016-07-31
JP5964300B2	Japan	B2	2016-08-03
RU2593720C2	Russian Federation	C2	2016-08-10
CN102369021B	China	B	2016-09-07
JP2016166209A	Japan	A	2016-09-15
AU2016222331A1	Australia	A1	2016-10-27
US2016355586A1	United States of America	A1	2016-12-08
CN106220734A	China	A	2016-12-14
JP6059761B2	Japan	B2	2017-01-11
BRPI0918122A8	Brazil	A8	2017-01-24
CN106432503A	China	A	2017-02-22
MX348166B	Mexico	B	2017-06-01
JP2017105779A	Japan	A	2017-06-15
IL246441A	Israel	A	2017-06-29
KR20170090525A	Republic of Korea	A	2017-08-07
IL213348A	Israel	A	2017-08-31
IL253751A0	Israel	A0	2017-09-28
IL253751D0	Israel	D0	2017-09-28
CN107226864A	China	A	2017-10-03
AU2016222331B2	Australia	B2	2017-12-07
KR101799337B1	Republic of Korea	B1	2017-12-20

Showing 100 of 155

80 legal events, as 12 offices reported them to INPADOC

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Events

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	Event	Code	Office
2026-07-23	Annual fee paid to national office [announced via postgrant information from national office to epo]GrantedPGFP	PGFP	EP
2026-07-21	Annual fee paid to national office [announced via postgrant information from national office to epo]GrantedPGFP	PGFP	EP
2026-07-16	Annual fee paid to national office [announced via postgrant information from national office to epo]GrantedPGFP	PGFP	EP
2026-07-16	Annual fee paid to national office [announced via postgrant information from national office to epo]GrantedPGFP	PGFP	EP
2026-07-15	Annual fee paid to national office [announced via postgrant information from national office to epo]GrantedPGFP	PGFP	EP
2026-07-11	Annual fee paid to national office [announced via postgrant information from national office to epo]GrantedPGFP	PGFP	EP
2026-07-10	Annual fee paid to national office [announced via postgrant information from national office to epo]GrantedPGFP	PGFP	EP
2026-07-09	Annual fee paid to national office [announced via postgrant information from national office to epo]GrantedPGFP	PGFP	EP
2026-07-09	Annual fee paid to national office [announced via postgrant information from national office to epo]GrantedPGFP	PGFP	EP
2026-07-01	Full renewal or maintenance fee paidST27 STATUS EVENT CODE: U-0-0-U10-U11 (AS PROVIDED BY THE NATIONAL OFFICE)U11	U11	CH
2025-10-21	Annual fee paid to national office [announced via postgrant information from national office to epo]GrantedPGFP	PGFP	EP
2025-10-09	Annual fee paid to national office [announced via postgrant information from national office to epo]GrantedPGFP	PGFP	EP
2025-07-18	Annual fee paid to national office [announced via postgrant information from national office to epo]GrantedPGFP	PGFP	EP
2025-07-15	Annual fee paid to national office [announced via postgrant information from national office to epo]GrantedPGFP	PGFP	EP
2023-06-21	Opt-out of the competence of the unified patent court (upc) registeredP01	P01	EP
2023-04-11	Fee paymentPLFP	PLFP	FR
2021-07-30	Lapsed in a contracting state [announced via postgrant information from national office to epo]LapsedPG25	PG25	EP
2021-07-30	Lapsed in a contracting state [announced via postgrant information from national office to epo]LapsedPG25	PG25	EP
2021-05-31	Lapsed in a contracting state [announced via postgrant information from national office to epo]LapsedPG25	PG25	EP
2020-06-30	Lapsed in a contracting state [announced via postgrant information from national office to epo]LapsedPG25	PG25	EP
2020-05-29	Lapsed in a contracting state [announced via postgrant information from national office to epo]LapsedPG25	PG25	EP
2020-03-31	Lapsed in a contracting state [announced via postgrant information from national office to epo]LapsedPG25	PG25	EP
2020-01-31	Lapsed in a contracting state [announced via postgrant information from national office to epo]LapsedPG25	PG25	EP
2019-08-30	Lapsed in a contracting state [announced via postgrant information from national office to epo]LapsedPG25	PG25	EP
2019-08-07	No opposition filedOpposition26N	26N	EP
2019-07-05	No opposition filed within time limitOppositionORIGINAL CODE: 0009261PLBE	PLBE	EP
2019-07-05	Information on the status of an ep patent application or granted ep patentGrantedSTATUS: NO OPPOSITION FILED WITHIN TIME LIMITSTAA	STAA	EP
2019-05-31	Lapsed in a contracting state [announced via postgrant information from national office to epo]LapsedPG25	PG25	EP
2019-05-31	Lapsed in a contracting state [announced via postgrant information from national office to epo]LapsedPG25	PG25	EP
2019-05-31	No opposition filed against granted patent, or epo opposition proceedings concluded without decisionGrantedR097	R097	DE
2019-04-30	Lapsed in a contracting state [announced via postgrant information from national office to epo]LapsedPG25	PG25	EP
2019-04-30	Lapsed in a contracting state [announced via postgrant information from national office to epo]LapsedPG25	PG25	EP
2019-04-30	Lapsed in a contracting state [announced via postgrant information from national office to epo]LapsedPG25	PG25	EP
2019-04-30	Lapsed in a contracting state [announced via postgrant information from national office to epo]LapsedPG25	PG25	EP
2019-02-28	Lapsed in a contracting state [announced via postgrant information from national office to epo]LapsedPG25	PG25	EP
2019-02-28	Lapsed in a contracting state [announced via postgrant information from national office to epo]LapsedPG25	PG25	EP
2019-02-27	Definitive protectionFG2A	FG2A	ES
2019-02-15	Deletion acc. to par. 5 (withdrawal of the translation of the ep patent)MK05	MK05	AT
2019-01-31	Lapsed in a contracting state [announced via postgrant information from national office to epo]LapsedPG25	PG25	EP
2019-01-31	Lapsed in a contracting state [announced via postgrant information from national office to epo]LapsedPG25	PG25	EP
2019-01-31	Lapsed in a contracting state [announced via postgrant information from national office to epo]LapsedPG25	PG25	EP
2019-01-31	Lapsed in a contracting state [announced via postgrant information from national office to epo]LapsedPG25	PG25	EP
2019-01-31	Lapsed in a contracting state [announced via postgrant information from national office to epo]LapsedPG25	PG25	EP
2019-01-31	Lapsed in a contracting state [announced via postgrant information from national office to epo]LapsedPG25	PG25	EP
2019-01-10	Invalidated european patentMG4D	MG4D	LT
2018-12-27	Translation of granted ep patentGrantedTRGR	TRGR	SE
2018-12-12	Translation for ep filed (entry of ep into country)FP	FP	NL
2018-09-27	Dpma publication of mentioned ep patent grantGrantedR096	R096	DE
2018-09-19	European patents granted designating irelandGrantedFG4D	FG4D	IE
2018-09-15	Reference to at number (ep patent validated in austria)REF	REF	AT
2018-08-31	European patent takes effect as a national patent in ch/liEP	EP	CH
2018-08-29	Designated contracting statesAK	AK	EP
2018-08-29	European patent grantedGrantedFG4D	FG4D	GB
2018-07-27	(expected) grantORIGINAL CODE: 0009210GRAA	GRAA	EP
2018-07-27	Information on the status of an ep patent application or granted ep patentGrantedSTATUS: THE PATENT HAS BEEN GRANTEDSTAA	STAA	EP
2018-04-25	Intention to grant announcedINTG	INTG	EP
2018-03-27	Despatch of communication of intention to grant a patentORIGINAL CODE: EPIDOSNIGR1GRAP	GRAP	EP
2018-03-23	Grant fee paidORIGINAL CODE: EPIDOSNIGR3GRAS	GRAS	EP
2018-03-23	Information on the status of an ep patent application or granted ep patentGrantedSTATUS: GRANT OF PATENT IS INTENDEDSTAA	STAA	EP
2017-11-29	Intention to grant announced (deleted)INTC	INTC	EP
2017-10-23	Information related to disapproval of communication of intention to grant by the applicant or resumption of examination proceedings by the epo deletedORIGINAL CODE: EPIDOSDIGR1GRAJ	GRAJ	EP
2017-10-23	Information on the status of an ep patent application or granted ep patentGrantedSTATUS: EXAMINATION IS IN PROGRESSSTAA	STAA	EP
2017-07-19	Intention to grant announcedINTG	INTG	EP
2017-06-21	Information provided on ipc code assigned before grantRIC1	RIC1	EP
2017-06-21	Information provided on ipc code assigned before grantRIC1	RIC1	EP
2017-06-21	Information provided on ipc code assigned before grantRIC1	RIC1	EP
2017-06-21	Information provided on ipc code assigned before grantRIC1	RIC1	EP
2017-06-21	Information provided on ipc code assigned before grantRIC1	RIC1	EP
2017-06-19	Despatch of communication of intention to grant a patentORIGINAL CODE: EPIDOSNIGR1GRAP	GRAP	EP
2017-06-19	Information on the status of an ep patent application or granted ep patentGrantedSTATUS: GRANT OF PATENT IS INTENDEDSTAA	STAA	EP
2016-11-25	Information on the status of an ep patent application or granted ep patentGrantedSTATUS: EXAMINATION IS IN PROGRESSSTAA	STAA	EP
2016-10-12	Party data changed (applicant data changed or rights of an application transferred)RAP1	RAP1	EP
2014-04-02	Party data changed (applicant data changed or rights of an application transferred)RAP1	RAP1	EP
2013-01-09	First examination report despatched17Q	17Q	EP
2010-12-01	Supplementary search report drawn up and despatchedA4	A4	EP
2010-11-19	Requests to designate patent in hong kongDE	DE	HK
2010-09-29	Request for extension of the european patent (deleted)DAX	DAX	EP
2010-03-03	Request for examination filed17P	17P	EP
2010-03-03	Designated contracting statesAK	AK	EP
2010-01-29	Public reference made under article 153(3) epc to a published international application that has entered the european phaseORIGINAL CODE: 0009012PUAI	PUAI	EP

Covalent diabodies and uses thereof

Abstract

Term

Members155

Over the term

Events

Numbers

Titles3

Classification

Designated states34