EP2016189A2
Droplet-based pyrosequencing
Abstract
The present invention relates to a droplet microactuator and to systems, apparatuses and methods employing the droplet microactuator for executing various protocols using discrete droplets. The invention includes a droplet microactuator or droplet microactuator system having one or more input reservoirs loaded with reagents for conducting biochemical reactions, such as the reagents described for use in nucleic acid amplification protocols, affinity-based assay protocols, sequencing protocols, and protocols for analyses of biological fluids.
Term
0.2 yearsto projected expiry
Projected expiry 11 December 2026, counted from filing; an application has no term until it is granted.
- Priority
- Filed
- Published
- Today
- Projected expiry
Every citation, both ways
| Document | Relation | Office | Cited during |
|---|---|---|---|
| WO2016197103A1 | Cited by | World Intellectual Property Organization (WIPO) | Applicant |
| EP3930901A4 | Cited by | European Patent Office (EPO) | Search report |
| US11389796B2 | Cited by | United States of America | Applicant |
| EP3303547A4 | Cited by | European Patent Office (EPO) | Search report |
| CN108026494A | Cited by | China | Search report |
| WO2022038304A1 | Cited by | World Intellectual Property Organization (WIPO) | International search |
| EP1418243A2 | Cites | European Patent Office (EPO) | Search report |
| US2006021875A1 | Cites | United States of America | Search report |
| WO9822625A1 | Cites | World Intellectual Property Organization (WIPO) | Search report |
| WO9954730A1 | Cites | World Intellectual Property Organization (WIPO) | Search report |
231 members in 12 offices
Priority claims21
| Document | Office | Kind | Date |
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| 745059P | United States of America | – | |
| 745039P | United States of America | – | |
| 745058P | United States of America | – | |
| 745073P | United States of America | – | |
| 74505906 | United States of America | P | |
| 74503906 | United States of America | P | |
| 74505806 | United States of America | P | |
| 74507306 | United States of America | P | |
| 745914P | United States of America | – | |
| 745950P | United States of America | – | |
| 74591406 | United States of America | P | |
| 74595006 | United States of America | P | |
| 746797P | United States of America | – | |
| 746801P | United States of America | – | |
| 74679706 | United States of America | P | |
| 74680106 | United States of America | P | |
| 806412P | United States of America | – | |
| 80641206 | United States of America | P | |
| 807104P | United States of America | – | |
| 80710406 | United States of America | P | |
| 2006047481 | United States of America | W |
Members231
| Document | Office | Kind | |
|---|---|---|---|
| US2007241068A1 | United States of America | A1 | |
| US2007242105A1 | United States of America | A1 | |
| US2007242111A1 | United States of America | A1 | |
| US2007243634A1 | United States of America | A1 | |
| CA2680061A1 | Canada | A1 | |
| CA2680532A1 | Canada | A1 | |
| WO2007120240A2 | World Intellectual Property Organization (WIPO) | A2 | |
| WO2007120241A2 | World Intellectual Property Organization (WIPO) | A2 | |
| WO2007123908A2 | World Intellectual Property Organization (WIPO) | A2 | |
| US2007275415A1 | United States of America | A1 | |
| US2008006535A1 | United States of America | A1 | |
| US2008038810A1 | United States of America | A1 | |
| US2008044893A1 | United States of America | A1 | |
| US2008044914A1 | United States of America | A1 | |
| US2008050834A1 | United States of America | A1 | |
| US2008053205A1 | United States of America | A1 | |
| CA2680062A1 | Canada | A1 | |
| WO2008051310A2 | World Intellectual Property Organization (WIPO) | A2 | |
| WO2007120240A3 | World Intellectual Property Organization (WIPO) | A3 | |
| WO2007120241A3 | World Intellectual Property Organization (WIPO) | A3 | |
| US2008230386A1 | United States of America | A1 | |
| WO2008116209A1 | World Intellectual Property Organization (WIPO) | A1 | |
| WO2007123908A3 | World Intellectual Property Organization (WIPO) | A3 | |
| US7439014B2 | United States of America | B2 | |
| US2008281471A1 | United States of America | A1 | |
| EP2016091A2 | European Patent Office (EPO) | A2 | |
| EP2016189A2This record | European Patent Office (EPO) | A2 | |
| EP2021103A2 | European Patent Office (EPO) | A2 | |
| WO2009026339A2 | World Intellectual Property Organization (WIPO) | A2 | |
| WO2008051310A3 | World Intellectual Property Organization (WIPO) | A3 | |
| WO2009052348A2 | World Intellectual Property Organization (WIPO) | A2 | |
| WO2009026339A3 | World Intellectual Property Organization (WIPO) | A3 | |
| US2009155902A1 | United States of America | A1 | |
| CN101472940A | China | A | |
| WO2009052348A3 | World Intellectual Property Organization (WIPO) | A3 | |
| CN101500694A | China | A | |
| EP2016091A4 | European Patent Office (EPO) | A4 | |
| WO2009111769A2 | World Intellectual Property Organization (WIPO) | A2 | |
| HK1127066A1 | Hong Kong, China | A1 | |
| HK1127091A1 | Hong Kong, China | A1 | |
| JP2009534653A | Japan | A | |
| US2009263834A1 | United States of America | A1 | |
| US2009280475A1 | United States of America | A1 | |
| US2009280476A1 | United States of America | A1 | |
| WO2009140373A2 | World Intellectual Property Organization (WIPO) | A2 | |
| WO2009140671A2 | World Intellectual Property Organization (WIPO) | A2 | |
| US2009291433A1 | United States of America | A1 | |
| EP2126038A1 | European Patent Office (EPO) | A1 | |
| WO2009111769A3 | World Intellectual Property Organization (WIPO) | A3 | |
| US2009311713A1 | United States of America | A1 | |
| WO2010006166A2 | World Intellectual Property Organization (WIPO) | A2 | |
| JP2010503516A | Japan | A | |
| US2010041086A1 | United States of America | A1 | |
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| WO2010042637A2 | World Intellectual Property Organization (WIPO) | A2 | |
| WO2009140373A3 | World Intellectual Property Organization (WIPO) | A3 | |
| WO2010006166A3 | World Intellectual Property Organization (WIPO) | A3 | |
| US2010116640A1 | United States of America | A1 | |
| US7727723B2 | United States of America | B2 | |
| WO2010027894A3 | World Intellectual Property Organization (WIPO) | A3 | |
| US2010140093A1 | United States of America | A1 | |
| US2010143963A1 | United States of America | A1 | |
| US2010151439A1 | United States of America | A1 | |
| WO2009140671A3 | World Intellectual Property Organization (WIPO) | A3 | |
| WO2010042637A3 | World Intellectual Property Organization (WIPO) | A3 | |
| US7763471B2 | United States of America | B2 | |
| EP2212683A2 | European Patent Office (EPO) | A2 | |
| US2010221713A1 | United States of America | A1 | |
| US2010258441A1 | United States of America | A1 | |
| US7815871B2 | United States of America | B2 | |
| US7816121B2 | United States of America | B2 | |
| US7822510B2 | United States of America | B2 | |
| US2010279374A1 | United States of America | A1 | |
| US2010291578A1 | United States of America | A1 | |
| EP2126038A4 | European Patent Office (EPO) | A4 | |
| EP2016091B1 | European Patent Office (EPO) | B1 | |
| EP2016189A4 | European Patent Office (EPO) | A4 | |
| US7851184B2 | United States of America | B2 | |
| AT490971T | Austria | T | |
| ATE490971T1 | Austria | T1 | |
| DE602006018794D1 | Germany | D1 | |
| EP2279405A2 | European Patent Office (EPO) | A2 | |
| EP2021103A4 | European Patent Office (EPO) | A4 | |
| EP2286228A2 | European Patent Office (EPO) | A2 | |
| US7901947B2 | United States of America | B2 | |
| ES2356777T3 | Spain | T3 | |
| US2011091989A1 | United States of America | A1 | |
| US2011097763A1 | United States of America | A1 | |
| US2011100823A1 | United States of America | A1 | |
| US2011104747A1 | United States of America | A1 | |
| US7939021B2 | United States of America | B2 | |
| US2011114490A1 | United States of America | A1 | |
| US2011118132A1 | United States of America | A1 | |
| WO2011084703A2 | World Intellectual Property Organization (WIPO) | A2 | |
| JP2011520449A | Japan | A | |
| US2011180571A1 | United States of America | A1 | |
| US2011186433A1 | United States of America | A1 | |
| US7998436B2 | United States of America | B2 | |
| US2011203930A1 | United States of America | A1 | |
| US8007739B2 | United States of America | B2 |
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| Lapsed in a contracting state [announced via postgrant information from national office to epo]LapsedPG25 | PG25 | EP | |
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| Patent lapsedLapsedMM4A | MM4A | IE | |
| Gb: european patent ceased through non-payment of renewal feeCeasedGBPC | GBPC | EP | |
| Lapsed because of non-payment of the annual feeLapsedMM | MM | NL | |
| Patent ceasedCeasedPL | PL | CH | |
| Application deemed withdrawn, or ip right lapsed, due to non-payment of renewal feeWithdrawnR119 | R119 | DE | |
| Annual fee paid to national office [announced via postgrant information from national office to epo]GrantedPGFP | PGFP | EP | |
| Annual fee paid to national office [announced via postgrant information from national office to epo]GrantedPGFP | PGFP | EP | |
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| Lapsed in a contracting state [announced via postgrant information from national office to epo]LapsedPG25 | PG25 | EP | |
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| No opposition filed against granted patent, or epo opposition proceedings concluded without decisionGrantedR097 | R097 | DE | |
| Lapsed in a contracting state [announced via postgrant information from national office to epo]LapsedPG25 | PG25 | EP | |
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| Lapsed in a contracting state [announced via postgrant information from national office to epo]LapsedPG25 | PG25 | EP | |
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| Information on the status of an ep patent application or granted ep patentGrantedSTATUS: NO OPPOSITION FILED WITHIN TIME LIMITSTAA | STAA | EP | |
| Lapsed in a contracting state [announced via postgrant information from national office to epo]LapsedPG25 | PG25 | EP | |
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| Deletion acc. to par. 5 (withdrawal of the translation of the ep patent)MK05 | MK05 | AT | |
| Lapsed in a contracting state [announced via postgrant information from national office to epo]LapsedPG25 | PG25 | EP | |
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| European patent takes effect as a national patent in ch/liEP | EP | CH | |
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| (expected) grantORIGINAL CODE: 0009210GRAA | GRAA | EP | |
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| Public reference made under article 153(3) epc to a published international application that has entered the european phaseORIGINAL CODE: 0009012PUAI | PUAI | EP |
Numbers
- Publication
- 2016189
- Application
- 68475888
Titles3
- German
- PYROSEQUENZIERUNG AUF TRÖPFCHENBASIS
- English
- DROPLET-BASED PYROSEQUENCING
- French
- PYROSÉQUENÇAGE À BASE DE GOUTTELETTES
Classification
- CPC, 25
- B01L3/502792
- B01L3/502715
- B01L3/502761
- B01L7/52
- B01L7/525
- B01L2200/027
- B01L2200/0668
- B01L2300/0654
- B01L2300/0816
- B01L2300/0861
- B01L2300/0864
- B01L2300/0867
- B01L2300/089
- B01L2300/1827
- B01L2400/0406
- B01L2400/0415
- B01L2400/043
- B01L2400/0436
- B01L2400/0442
- B01L2400/0448
- C12Q1/6869
- G01N33/49
- B01F31/65
- B01F33/3021
- B01F33/3031
- IPC, 2
- C12Q1 68
- C07H21 00
Designated states36
- Contracting states, 31
- Austria
- Belgium
- Bulgaria
- Switzerland
- Cyprus
- Czechia
- Germany
- Denmark
- Estonia
- Spain
- Finland
- France
- United Kingdom
- Greece
- Hungary
- Ireland
- Iceland
- Italy
- Liechtenstein
- Lithuania
- Luxembourg
- Latvia
- Monaco
- Netherlands (Kingdom of the)
and 7 moreShow fewer
- Poland
- Portugal
- Romania
- Sweden
- Slovenia
- Slovakia
- Türkiye
- Extension states, 5
- Albania
- Bosnia and Herzegovina
- Croatia
- North Macedonia
- Serbia