Emulsion compositions for the parenteral and/or oral administration of sparingly water soluble ionizable hydrophobic drugs
Abstract
This disclosure describes quick breaking, invivo, intravenous, intramuscular, intraarticular and/or oral fat emulsion compositions which incorporate the use of benzyl alcohol as a cosurfactant and/or a cosolvent in combination with materials such as synthetic surfactants, e.g. sorbitan triisostearate, triglycerol diisostearate or triglycerol pentaoleate; naturally occurring vegetable oils, e.g. sesame oil, and soybean oil; natural lecithins such as egg lecithin or soy lecithin; saturated or unsaturated aliphatic acids, e.g. oleic acid, hexanoic acid and linolenic acid; and other excipients such as glycerine, polyvinylpyrrolidone, Pluronic® F-68 dl-α-tocopherol.
Term
Term ended
Projected expiry passed 19 August 2006, 20.1 years ago.
- Priority
- Filed
- Published
- Projected expiry
- Today
Every citation, both ways
| Document | Relation | Office | Category | Cited during |
|---|---|---|---|---|
| FR2300554A1 | Cites | France | Y | Search report |
| US3116203A | Cites | United States of America | Y | Search report |
| US4168308A | Cites | United States of America | Y | Search report |
34 members in 18 offices
Priority claims5
| Document | Office | Kind | Date |
|---|---|---|---|
| 776306 | United States of America | – | |
| 77630685 | United States of America | A | |
| 77630685 | United States of America | A | |
| 776306 | – | – | – |
| US19850776306 | – | – | – |
Members34
| Document | Office | Kind | |
|---|---|---|---|
| DK438286D0 | Denmark | D0 | |
| FI863728A0 | Finland | A0 | |
| NO863670D0 | Norway | D0 | |
| GR862354B | Greece | B | |
| DK438286A | Denmark | A | |
| FI863728A | Finland | A | |
| FI863728A7 | Finland | A7 | |
| FI863728L | Finland | L | |
| NO863670L | Norway | L | |
| AU6269686A | Australia | A | |
| EP0215313A2 | European Patent Office (EPO) | A2 | |
| JPS6267018A | Japan | A | |
| KR870002835A | Republic of Korea | A | |
| KR870002835A | Republic of Korea | A | |
| ZA867009B | South Africa | B | |
| EP0215313A3This record | European Patent Office (EPO) | A3 | |
| HUT43947A | Hungary | A | |
| ES2002750A6 | Spain | A6 | |
| US4784845A | United States of America | A | |
| PH23736A | Philippines | A | |
| KR890004684B1 | Republic of Korea | B1 | |
| KR890004684B1 | Republic of Korea | B1 | |
| AU591705B2 | Australia | B2 | |
| HU199282B | Hungary | B | |
| NZ217484A | New Zealand | A | |
| CA1272447A | Canada | A | |
| EP0215313B1 | European Patent Office (EPO) | B1 | |
| AT78683T | Austria | T | |
| ATE78683T1 | Austria | T1 | |
| DE3686221D1 | Germany | D1 | |
| DK165730B | Denmark | B | |
| DE3686221T2 | Germany | T2 | |
| AR242716A1 | Argentina | A1 | |
| DK165730C | Denmark | C |
41 legal events, as 3 offices reported them to INPADOC
Over the term
Point at a mark for the eventEvents
| Event | Code | Office | |
|---|---|---|---|
| Lapsed in a contracting state [announced via postgrant information from national office to epo]LapsedPG25 | PG25 | EP | |
| Notification of lapseLapsedST | ST | FR | |
| Se: european patent has lapsedLapsedEUG | EUG | EP | |
| Nl: lapsed or anulled due to non-payment of the annual feeLapsedNLV4 | NLV4 | EP | |
| Lapsed in a contracting state [announced via postgrant information from national office to epo]LapsedPG25 | PG25 | EP | |
| Lapsed in a contracting state [announced via postgrant information from national office to epo]LapsedPG25 | PG25 | EP | |
| Gb: european patent ceased through non-payment of renewal feeCeasedGBPC | GBPC | EP | |
| Patent ceasedCeasedPL | PL | CH | |
| Lapsed in a contracting state [announced via postgrant information from national office to epo]LapsedPG25 | PG25 | EP | |
| Be: lapsedLapsedBERE | BERE | EP | |
| Lapsed in a contracting state [announced via postgrant information from national office to epo]LapsedPG25 | PG25 | EP | |
| Lapsed in a contracting state [announced via postgrant information from national office to epo]LapsedPG25 | PG25 | EP | |
| Lapsed in a contracting state [announced via postgrant information from national office to epo]LapsedPG25 | PG25 | EP | |
| Lapsed in a contracting state [announced via postgrant information from national office to epo]LapsedPG25 | PG25 | EP | |
| Lapsed in a contracting state [announced via postgrant information from national office to epo]LapsedPG25 | PG25 | EP | |
| Lapsed in a contracting state [announced via postgrant information from national office to epo]LapsedPG25 | PG25 | EP | |
| Se: european patent in force in swedenEAL | EAL | EP | |
| Annual fee paid to national office [announced via postgrant information from national office to epo]GrantedPGFP | PGFP | EP | |
| Annual fee paid to national office [announced via postgrant information from national office to epo]GrantedPGFP | PGFP | EP | |
| Annual fee paid to national office [announced via postgrant information from national office to epo]GrantedPGFP | PGFP | EP | |
| Annual fee paid to national office [announced via postgrant information from national office to epo]GrantedPGFP | PGFP | EP | |
| Annual fee paid to national office [announced via postgrant information from national office to epo]GrantedPGFP | PGFP | EP | |
| Annual fee paid to national office [announced via postgrant information from national office to epo]GrantedPGFP | PGFP | EP | |
| Annual fee paid to national office [announced via postgrant information from national office to epo]GrantedPGFP | PGFP | EP | |
| Annual fee paid to national office [announced via postgrant information from national office to epo]GrantedPGFP | PGFP | EP | |
| No opposition filedOpposition26N | 26N | EP | |
| No opposition filed within time limitOppositionORIGINAL CODE: 0009261PLBE | PLBE | EP | |
| Information on the status of an ep patent application or granted ep patentGrantedSTATUS: NO OPPOSITION FILED WITHIN TIME LIMITSTAA | STAA | EP | |
| Fr: translation filedET | ET | EP | |
| It: translation for a ep patent filedITF | ITF | EP | |
| It: translation for a ep patent filedITF | ITF | EP | |
| Corresponds to:REF | REF | EP | |
| Designated contracting statesAK | AK | EP | |
| Corresponds to:REF | REF | EP | |
| (expected) grantORIGINAL CODE: 0009210GRAA | GRAA | EP | |
| First examination report despatched17Q | 17Q | EP | |
| Request for examination filed17P | 17P | EP | |
| Designated contracting statesAK | AK | EP | |
| Search report despatchedORIGINAL CODE: 0009013PUAL | PUAL | EP | |
| Designated contracting statesAK | AK | EP | |
| Public reference made under article 153(3) epc to a published international application that has entered the european phaseORIGINAL CODE: 0009012PUAI | PUAI | EP |
Numbers
- Publication
- 0215313
- Publication, DOCDB
- 0215313
- Publication, EPODOC
- EP0215313
- Application
- 86111470
- Application, DOCDB
- 86111470
- Application, EPODOC
- EP19860111470
Titles3
- English
- Emulsion compositions for the parenteral and/or oral administration of sparingly water soluble ionizable hydrophobic drugs
- French
- Emulsions pour l'administration parentérale et/ou orale de médicaments peu solubles dans l'eau, ionisables et hydrophobes
- German
- Emulsionen zur parenteralen und/oder oralen Verabreichung schwer wasserlöslicher ionisierbarer hydrophober Arzneistoffe
Classification
- CPC, 5
- A61K9/0019
- A61K9/10
- A61K9/107
- A61K47/10
- A61K47/44
- IPC, 6
- A61K9 10
- A61K9 00
- A61K9 107
- A61K47 00
- A61K47 10
- A61K47 44
Designated states1
- Contracting states, 1
- Sweden