CL2016001031A1

Immediate Release Abuse-Deterrent Granulated Dosage Forms

Abstract

An abuse-preventing immediate release dosage form is disclosed, comprising: a) coated core particles comprising: i. A core comprising a gelling polymer and a wax; ii. An active pharmaceutical layer surrounding the nucleus, comprising a drug susceptible to abuse; iii. At least one layer surrounding the active pharmaceutical layer comprising a pH sensitive film comprising a pH sensitive polymer that is insoluble in water at a pH greater than 5 and is soluble in water at a pH below 5; and b) a matrix comprising a disintegrant and a gelling polymer. Also disclosed is the use of the dosage form to prepare a medicine useful to prevent, alleviate or lessen a level of pain and to prevent the abuse of a narcotic analgesic drug, among others.

Term

No projected expiry on record.

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40 members in 15 offices

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Priority claims
DocumentOfficeKindDate
201361898207United States of AmericaP
61898207United States of America
14333986United States of America
2014047014United States of AmericaW
201414333986United States of AmericaA
PCTUS2014047014World Intellectual Property Organization (WIPO)
14477354United States of America
2014054061United States of AmericaW
201414477354United States of AmericaA
PCTUS2014054061World Intellectual Property Organization (WIPO)
14484793United States of America
201414484793United States of AmericaA

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US2015118295A1United States of AmericaA1
US2015118300A1United States of AmericaA1
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CA2900858A1CanadaA1
WO2015065547A1World Intellectual Property Organization (WIPO)A1
WO2015065586A1World Intellectual Property Organization (WIPO)A1
WO2015066172A1World Intellectual Property Organization (WIPO)A1
CN105682647AChinaA
KR20160070839ARepublic of KoreaA
IL245125A0IsraelA0
IL245125D0IsraelD0
PE20160606A1PeruA1
EA201690874A1Eurasian Patent Organization (EAPO)A1
US2016250203A1United States of AmericaA1
EP3062778A1European Patent Office (EPO)A1
CL2016001031A1This recordChileA1
JP2016535773AJapanA
MX2016005482AMexicoA
CA2900858CCanadaC
US9707224B2United States of AmericaB2
EP3062778A4European Patent Office (EPO)A4
HK1223856AHong Kong, ChinaA
HK1223856A1Hong Kong, ChinaA1
US9757371B2United States of AmericaB2
US2018185354A1United States of AmericaA1
EA032013B1Eurasian Patent Organization (EAPO)B1
ZA201604451BSouth AfricaB
AU2014342412B2AustraliaB2
US10568881B2United States of AmericaB2
JP6659925B2JapanB2
US2020155544A1United States of AmericaA1
IL245125AIsraelA
IL245125BIsraelB
US11207318B2United States of AmericaB2
KR102363573B1Republic of KoreaB1
US2022071990A1United States of AmericaA1
US11844796B2United States of AmericaB2
MX384376BMexicoB