Immediate Release Abuse-Deterrent Granulated Dosage Forms
Abstract
An abuse-preventing immediate release dosage form is disclosed, comprising: a) coated core particles comprising: i. A core comprising a gelling polymer and a wax; ii. An active pharmaceutical layer surrounding the nucleus, comprising a drug susceptible to abuse; iii. At least one layer surrounding the active pharmaceutical layer comprising a pH sensitive film comprising a pH sensitive polymer that is insoluble in water at a pH greater than 5 and is soluble in water at a pH below 5; and b) a matrix comprising a disintegrant and a gelling polymer. Also disclosed is the use of the dosage form to prepare a medicine useful to prevent, alleviate or lessen a level of pain and to prevent the abuse of a narcotic analgesic drug, among others.
Term
No projected expiry on record.
- Priority
- Filed
- Published
- Today
40 members in 15 offices
Priority claims12
| Document | Office | Kind | Date |
|---|---|---|---|
| 201361898207 | United States of America | P | |
| 61898207 | United States of America | – | |
| 14333986 | United States of America | – | |
| 2014047014 | United States of America | W | |
| 201414333986 | United States of America | A | |
| PCTUS2014047014 | World Intellectual Property Organization (WIPO) | – | |
| 14477354 | United States of America | – | |
| 2014054061 | United States of America | W | |
| 201414477354 | United States of America | A | |
| PCTUS2014054061 | World Intellectual Property Organization (WIPO) | – | |
| 14484793 | United States of America | – | |
| 201414484793 | United States of America | A |
Members40
| Document | Office | Kind | |
|---|---|---|---|
| US2015118295A1 | United States of America | A1 | |
| US2015118300A1 | United States of America | A1 | |
| US2015118301A1 | United States of America | A1 | |
| US2015118302A1 | United States of America | A1 | |
| US2015118303A1 | United States of America | A1 | |
| CA2900858A1 | Canada | A1 | |
| WO2015065547A1 | World Intellectual Property Organization (WIPO) | A1 | |
| WO2015065586A1 | World Intellectual Property Organization (WIPO) | A1 | |
| WO2015066172A1 | World Intellectual Property Organization (WIPO) | A1 | |
| CN105682647A | China | A | |
| KR20160070839A | Republic of Korea | A | |
| IL245125A0 | Israel | A0 | |
| IL245125D0 | Israel | D0 | |
| PE20160606A1 | Peru | A1 | |
| EA201690874A1 | Eurasian Patent Organization (EAPO) | A1 | |
| US2016250203A1 | United States of America | A1 | |
| EP3062778A1 | European Patent Office (EPO) | A1 | |
| CL2016001031A1This record | Chile | A1 | |
| JP2016535773A | Japan | A | |
| MX2016005482A | Mexico | A | |
| CA2900858C | Canada | C | |
| US9707224B2 | United States of America | B2 | |
| EP3062778A4 | European Patent Office (EPO) | A4 | |
| HK1223856A | Hong Kong, China | A | |
| HK1223856A1 | Hong Kong, China | A1 | |
| US9757371B2 | United States of America | B2 | |
| US2018185354A1 | United States of America | A1 | |
| EA032013B1 | Eurasian Patent Organization (EAPO) | B1 | |
| ZA201604451B | South Africa | B | |
| AU2014342412B2 | Australia | B2 | |
| US10568881B2 | United States of America | B2 | |
| JP6659925B2 | Japan | B2 | |
| US2020155544A1 | United States of America | A1 | |
| IL245125A | Israel | A | |
| IL245125B | Israel | B | |
| US11207318B2 | United States of America | B2 | |
| KR102363573B1 | Republic of Korea | B1 | |
| US2022071990A1 | United States of America | A1 | |
| US11844796B2 | United States of America | B2 | |
| MX384376B | Mexico | B |
Numbers
- Publication
- 201601031
- Application
- 1031
Titles2
- Spanish
- FORMA DE DOSIFICACIÓN DE LIBERACIÓN INMEDIATA QUE EVITA EL ABUSO, QUE COMPRENDE PARTÍCULAS DE NÚCLEO RECUBIERTAS Y UNA MATRIZ; SU USO PARA PREPARAR UN MEDICAMENTO ÚTIL PARA PREVENIR, ALIVIAR O AMINORAR UN NIVEL DE DOLOR Y PARA PREVENIR EL ABUSO DE UN FÁRMACO ANALGÉSICO NARCÓTICO, ENTRE OTROS.
- English
- ABUSE PREVENTION, IMMEDIATE RELEASE DOSAGE FORM, COMPRISING COATED CORE PARTICLES AND A MATRIX; ITS USE TO PREPARE A USEFUL MEDICATION TO PREVENT, RELIEVE OR REDUCED A LEVEL OF PAIN AND TO PREVENT THE ABUSE OF A NARCOTIC ANALGESIC DRUG, AMONG OTHERS.
Classification
- CPC, 29
- A61K9/2081
- A61K31/485
- A61K9/5026
- A61K9/5078
- A61K31/167
- A61K31/165
- A61K31/515
- A61K31/5513
- A61K31/135
- A61K31/437
- A61K31/554
- A61K31/137
- A61K31/4458
- A61P25/04
- A61K9/0053
- A61K31/616
- A61K9/1676
- A61K9/2009
- A61K9/2013
- A61K9/2018
- A61K9/2027
- A61K9/2054
- A61K9/2063
- A61K31/192
- A61K31/4402
- A61K9/5015
- A61K9/5031
- A61K9/5047
- A61K31/16
- IPC, 4
- A61K31 485
- A61K9 20
- A61K9 22
- A61P25 04