Optically pure salts of pyridinylmethyl sulfinyl-ih- benzimidazole compounds
Abstract
The novel optically pure compounds Na+, Mg2+, Li+, K+. Ca2+ and N+(R)4 salts of (+)-5-methoxy-2-[[(4-methoxy-3,5- dimethyl-2-pyridinyl)methyl]sulfinyl]-1H-benzimidazole or (-)-5-methoxy-2-[[(4-methoxy-3,5-dimethyl-2- pyridinyl)methyl]sulfinyl]-1H-benzimidazole, where R is an alkyl with 1-4 carbon atoms, processes for the preparation thereof and pharmaceutical preparations containing the compounds as active ingredients, as well as the use of the compounds in pharmaceutical preparations and intermediates obtained by preparing the compounds. The novel compounds are represented by: Ia (+)-enantiomer Ib (-)-enantiomer wherein n is 1 or 2 and X is Na+, Mg2+, Li+, K+, Ca2+ or N+(R)4.
Term
Term ended
Projected expiry passed 27 May 2014, 12.3 years ago.
- Priority
- Filed
- Published
- Projected expiry
- Today
Every citation, both ways
| Document | Relation | Office | Cited during |
|---|---|---|---|
| US10603283B2 | Cited by | United States of America | Applicant |
| US6733778B1 | Cited by | United States of America | Applicant |
| US9801824B2 | Cited by | United States of America | Applicant |
| US6174548B1 | Cited by | United States of America | Applicant |
| US9707181B2 | Cited by | United States of America | Applicant |
| US6855336B2 | Cited by | United States of America | Applicant |
| US6780435B2 | Cited by | United States of America | Applicant |
| US6096340A | Cited by | United States of America | Search report |
115 members in 44 offices
Priority claims8
| Document | Office | Kind | Date |
|---|---|---|---|
| 9301830 | Sweden | A | |
| 9301830 | Sweden | A | |
| 9400509 | Sweden | W | |
| 9400509 | Sweden | W | |
| 93018307 | – | – | – |
| PCTSE9400509 | – | – | – |
| SE19930001830 | – | – | – |
| WO1994SE00509 | – | – | – |
Members115
| Document | Office | Kind | |
|---|---|---|---|
| SE9301830D0 | Sweden | D0 | |
| IS4161A | Iceland | A | |
| CA2139653A1This record | Canada | A1 | |
| CA2337581A1 | Canada | A1 | |
| WO9427988A1 | World Intellectual Property Organization (WIPO) | A1 | |
| AU6902494A | Australia | A | |
| LTIP1941A | Lithuania | A | |
| IL109684D0 | Israel | D0 | |
| MA23210A1 | Morocco | A1 | |
| NO950263D0 | Norway | D0 | |
| NO950263L | Norway | L | |
| FI950377A | Finland | A | |
| FI950377L | Finland | L | |
| HU9500247D0 | Hungary | D0 | |
| ZA943557B | South Africa | B | |
| TNSN94058A1 | Tunisia | A1 | |
| PL307261A1 | Poland | A1 | |
| EP0652872A1 | European Patent Office (EPO) | A1 | |
| LT3287B | Lithuania | B | |
| KR950702553A | Republic of Korea | A | |
| SI9420002A | Slovenia | A | |
| SK10195A3 | Slovakia | A3 | |
| CN1110477A | China | A | |
| CZ20295A3 | Czechia | A3 | |
| JPH07509499A | Japan | A | |
| LV11034A | Latvia | A | |
| HUT71888A | Hungary | A | |
| SE9601383D0 | Sweden | D0 | |
| LV11034B | Latvia | B | |
| RU95105587A | Russian Federation | A | |
| NZ266915A | New Zealand | A | |
| HRP940307A2 | Croatia | A2 | |
| AU676337B2 | Australia | B2 | |
| ES2099047T1 | Spain | T1 | |
| YU31494A | Yugoslavia, later Serbia and Montenegro (until 2006) | A | |
| GR970300012T1 | Greece | T1 | |
| DE652872T1 | Germany | T1 | |
| US5693818A | United States of America | A | |
| US5714504A | United States of America | A | |
| SG49283A1 | Singapore | A1 | |
| EE03157B1 | Estonia | B1 | |
| US5877192A | United States of America | A | |
| HK1008330A1 | Hong Kong, China | A1 | |
| RU2137766C1 | Russian Federation | C1 | |
| NO307378B1 | Norway | B1 | |
| TW389761B | Taiwan Province of China | B | |
| CN1259346A | China | A | |
| EP1020460A2 | European Patent Office (EPO) | A2 | |
| EP1020461A2 | European Patent Office (EPO) | A2 | |
| PL178994B1 | Poland | B1 | |
| CN1055469C | China | C | |
| US6143771A | United States of America | A | |
| EP0652872B1 | European Patent Office (EPO) | B1 | |
| AT197452T | Austria | T | |
| ATE197452T1 | Austria | T1 | |
| DE69426254D1 | Germany | D1 | |
| HK1028044A1 | Hong Kong, China | A1 | |
| HK1028045A1 | Hong Kong, China | A1 | |
| ES2099047T3 | Spain | T3 | |
| DK0652872T3 | Denmark | T3 | |
| CZ287876B6 | Czechia | B6 | |
| PT652872E | Portugal | E | |
| GR3035365T3 | Greece | T3 | |
| DE69426254T2 | Germany | T2 | |
| HRP940307B1 | Croatia | B1 | |
| CA2139653C | Canada | C | |
| DZ1785A1 | Algeria | A1 | |
| IL109684A | Israel | A | |
| SK282524B6 | Slovakia | B6 | |
| IS1854B | Iceland | B | |
| CY2224B1 | Cyprus | B1 | |
| CN1107503C | China | C | |
| YU49065B | Yugoslavia, later Serbia and Montenegro (until 2006) | B | |
| EP1020460A3 | European Patent Office (EPO) | A3 | |
| UA60289C2 | Ukraine | C2 | |
| KR100337274B1 | Republic of Korea | B1 | |
| JP2004043493A | Japan | A | |
| JP2004043494A | Japan | A | |
| JP3549111B2 | Japan | B2 | |
| US6875872B1 | United States of America | B1 | |
| US2006004057A1 | United States of America | A1 | |
| MY121192A | Malaysia | A | |
| SA821B1 | Saudi Arabia | B1 | |
| SA94140756B1 | Saudi Arabia | B1 | |
| EP1020461A3 | European Patent Office (EPO) | A3 | |
| FI20070002A | Finland | A | |
| FI20070002A7 | Finland | A7 | |
| FI20070002L | Finland | L | |
| FI117755B | Finland | B | |
| JP3959056B2 | Japan | B2 | |
| JP4039999B2 | Japan | B2 | |
| US2008312449A1 | United States of America | A1 | |
| EP1020460B1 | European Patent Office (EPO) | B1 | |
| EP1020461B1 | European Patent Office (EPO) | B1 | |
| PT1020460E | Portugal | E | |
| PT1020461E | Portugal | E | |
| DK1020460T3 | Denmark | T3 | |
| DK1020461T3 | Denmark | T3 | |
| CL2009000805A1 | Chile | A1 | |
| DE69435220D1 | Germany | D1 |
2 legal events, as the office reported them to INPADOC
Over the term
Point at a mark for the eventEvents
| Event | Code | |
|---|---|---|
| ExpiryMKEX | MKEX | |
| Examination requestEEER | EEER |
Numbers
- Publication, DOCDB
- 2139653
- Publication, EPODOC
- CA2139653
- Application
- 2139653
- Application, DOCDB
- 2139653
- Application, EPODOC
- CA19942139653
Titles2
- English
- OPTICALLY PURE SALTS OF PYRIDINYLMETHYL SULFINYL-IH- BENZIMIDAZOLE COMPOUNDS
- French
- SELS OPTIQUEMENT PURS DE COMPOSES PYRIDINYLMETHYLSULFINYL-IH-BENZIMIDAZOLE
Classification
- CPC, 8
- C07D401/12
- A61P1/00
- A61P1/04
- A61P17/06
- A61P19/06
- A61P29/00
- A61P31/04
- A61K31/44
- IPC, 23
- C07D401 12
- A61K
- A61K31 33
- A61K31 395
- A61K31 415
- A61K31 44
- A61K31 4427
- A61K31 4439
- A61P1 00
- A61P1 04
- A61P17 06
- A61P19 06
- A61P29 00
- A61P31 04
- C07D
- C07D213 00
- C07D213 32
- C07D213 63
- C07D235 00
- C07D235 28
- C07D239 93
- C07F1 00
- C07F3 00