CA2139653A1

Optically pure salts of pyridinylmethyl sulfinyl-ih- benzimidazole compounds

Abstract

The novel optically pure compounds Na+, Mg2+, Li+, K+. Ca2+ and N+(R)4 salts of (+)-5-methoxy-2-[[(4-methoxy-3,5- dimethyl-2-pyridinyl)methyl]sulfinyl]-1H-benzimidazole or (-)-5-methoxy-2-[[(4-methoxy-3,5-dimethyl-2- pyridinyl)methyl]sulfinyl]-1H-benzimidazole, where R is an alkyl with 1-4 carbon atoms, processes for the preparation thereof and pharmaceutical preparations containing the compounds as active ingredients, as well as the use of the compounds in pharmaceutical preparations and intermediates obtained by preparing the compounds. The novel compounds are represented by: Ia (+)-enantiomer Ib (-)-enantiomer wherein n is 1 or 2 and X is Na+, Mg2+, Li+, K+, Ca2+ or N+(R)4.

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Projected expiry passed 27 May 2014, 12.3 years ago.

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