Nova Patents
ATE449178T1

Recombinant proteins of a pakistani strain of hepatitis e and their use in diagnostic methods and vaccines.

Abstract

A strain of hepatitis E virus from Pakistan (SAR-55) implicated in an epidemic of enterically transmitted non-A, non-B hepatitis, now called hepatitis E, is disclosed. The invention relates to the expression of the whole structural region of SAR-55, designated open reading frame 2 (ORF-2), in a eukaryotic expression system. The expressed protein is capable of forming HEV virus-like particles which can serve as an antigen in diagnostic immunoassays and as an immunogen or vaccine to protect against infection by hepatitis E.

Term

Term ended

Projected expiry passed 17 September 2013, 13 years ago.

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59 members in 15 offices

This recordMember, by publication datePriority claim5 more offices are in the list below

Priority claims2

Priority claims
DocumentOfficeKindDate
94726392United States of AmericaA
9308849United States of AmericaW

Members59

Family members, oldest first
DocumentOfficeKind
CA2144855A1CanadaA1
WO9406913A2World Intellectual Property Organization (WIPO)A2
AU5162593AAustraliaA
WO9406913A3World Intellectual Property Organization (WIPO)A3
EP0662133A1European Patent Office (EPO)A1
CA2201588A1CanadaA1
WO9610580A2World Intellectual Property Organization (WIPO)A2
AU3830995AAustraliaA
JPH08504096AJapanA
WO9610580A3World Intellectual Property Organization (WIPO)A3
ZA964447BSouth AfricaB
CA2226457A1CanadaA1
WO9639501A2World Intellectual Property Organization (WIPO)A2
AU6300296AAustraliaA
WO9639501A3World Intellectual Property Organization (WIPO)A3
NO971529D0NorwayD0
NO971529LNorwayL
EP0784631A1European Patent Office (EPO)A1
KR970706300ARepublic of KoreaA
CN1168698AChinaA
EP0832214A2European Patent Office (EPO)A2
AU689447B2AustraliaB2
AR002758A1ArgentinaA1
JPH11500001AJapanA
NZ295056ANew ZealandA
AU712901B2AustraliaB2
EP0832214B1European Patent Office (EPO)B1
AT198352TAustriaT
ATE198352T1AustriaT1
DE69611368D1GermanyD1
US6207416B1United States of AmericaB1
US2001010899A1United States of AmericaA1
DE69611368T2GermanyT2
US6287759B1United States of AmericaB1
KR100318516B1Republic of KoreaB1
KR100332602B1Republic of KoreaB1
US2002068820A1United States of AmericaA1
US6458940B2United States of AmericaB2
US6509149B2United States of AmericaB2
KR100359526B1Republic of KoreaB1
US2003055240A1United States of AmericaA1
US6696242B1United States of AmericaB1
US6706873B1United States of AmericaB1
CN1148450CChinaC
US6787145B1United States of AmericaB1
JP2005013220AJapanA
JP2006149393AJapanA
JP3889808B2JapanB2
CA2226457CCanadaC
CA2144855CCanadaC
NO326399B1NorwayB1
EP0662133B1European Patent Office (EPO)B1
AT449178TAustriaT
ATE449178T1This recordAustriaT1
DE69334299D1GermanyD1
ES2336282T3SpainT3
EP0784631B1European Patent Office (EPO)B1
AT518879TAustriaT
ATE518879T1AustriaT1