Systems and methods for high speed variable printing

Systems and methods for high-speed variable printing are provided. Ink jet technology and lithographic systems may be combined in such a way to create a fully variable and high-quality print system. Ink is applied to a first cylinder. Aqueous solution is applied to a second cylinder to produce a negative image. At least a portion of the ink from the first cylinder is transferred to the second cylinder. A positive image in ink is then transferred from the second cylinder to a print medium, and residue ink and aqueous solution is cleaned from the second cylinder. The systems and methods described herein may be used to create high-quality one-to-one marketing applications.