AT501522T

Tandem time of flight mass spectrometer and method of use

Abstract

In turn to provide comprehensive (i.e. fast and keen) MS-MS switch, the inventor used by the time nested separator of two flight time (TOF) mass analyzer by. The Lizi cover (1) to 100eV) and rising speed and a long TOF1 is separated from the lower ion the work; the fragment ns the working is higher than the clamped keV energies fast and short TOF2 and analyzing quality. Split feeble-minded unit is TOF1 and TOF2 is) is mainly composed of reducing unit and a pneumatic high voltage, accelerates to be the damping. Wherein the separation of TOF1 requires a millisecond time, analyses of the TOF2 the lower microsecond, therefore the invention provides is carried out comprehensive MS-MS analyses of multiple precursor ns of each single pulse ion. By a novel TOF1 analyzer, the separation installed in TOF1 wherein the. TOF-TOF a substrate by static TOF1, here, wheel sieve of the cylindrical and multiple separators are received ion focusing lens with the spiratron described static TOF1 related. And the novel mixed TOF1 analyzer, a combined radiofrequency and two OUTPUT fields, can prevent ingress a better performance. The RF field of the feeble-minded ion the TOF1 analyzer, two of DC fields improve the resolution through the compensation relatively large energy connecting.

Term

Term ended

Expired 29 April 2023, 3.4 years ago.

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17 members in 11 offices

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Priority claims
DocumentOfficeKindDate
0216438United KingdomA
0313262United States of AmericaW

Members17

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DocumentOfficeKind
GB2390935AUnited KingdomA
CA2492808A1CanadaA1
WO2004008481A1World Intellectual Property Organization (WIPO)A1
AU2003228749A1AustraliaA1
EP1522087A1European Patent Office (EPO)A1
KR20050056937ARepublic of KoreaA
CN1689134AChinaA
US2005242279A1United States of AmericaA1
JP2005538346AJapanA
US7196324B2United States of AmericaB2
US2007187585A1United States of AmericaA1
JP4435682B2JapanB2
CN1689134BChinaB
EP1522087B1European Patent Office (EPO)B1
AT501522TThis recordAustriaT
ATE501522T1AustriaT1
DE60336318D1GermanyD1