AT463576T

Aggregate-free urate oxidase for preparation of non-immunogenic polymer conjugates

Abstract

A free of a material of crude protein or a recombinant protein, wherein the pig urico-oxidase mutein with a at least of said conjugated polymer, a have a free of with immunogenicity, comprising contacting the surface of the basic retention of protein in the conjugate. The conjugate is suitable for the treatment of diseases, and is selected from the micro of similar aggregate's of a protein product preparation ratio, and possibly induction to form the antibody of and/or accelerate to remove.

Term

Term ended

Expired 7 February 2021, 5.6 years ago.

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191 members in 28 offices

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Priority claims
DocumentOfficeKindDate
50173000United States of AmericaA
0140069United States of AmericaW

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EP1254237B1European Patent Office (EPO)B1
AT463576TThis recordAustriaT
ATE463576T1AustriaT1
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