Compositions of restricted cells capable of rapid growth which produce proliferation suppressive materials, and uses thereof

[Subject] Although the cell can grow up to be transplant medical treatment quickly by useful biocompatibility, the composite of the penetrable structure which does not allow unrestricted multiplication is offered. [Solution means] The Gang cell produced a lot of 30, 000 or more-molecular weight cell-growth control substances, and did not show unrestricted multiplication while increasing quickly by wrapping in in the macro bead of agarose, cultivating or transplanting to an animal by in vitro one. This phenomenon is straddling two or more systems of the cell type and the kind. The production method of such a composite and its use were also indicated. [Selection figure] Nothing