AT407938T

Glucopyranosyl-substituted benzene derivatives, medicaments containing such compounds, their use and process for their manufacture

Abstract

Substituted benzene derivative glucopyranosyl selected from: (1) 1-methyl-2- (4-cyclopentyloxy-benzyl) -4- (Beta -D-glucopyranos-1-yl) -benzene (2) 1-methyl-2 - [4 - ((R) -tetrahydrofuran-3-yloxy) -benzyl] -4- (Beta -D-glucopyranos-1-yl) -benzene (3) 1-methyl-2- [4 - ((S ) -tetrahydrofuran-3-yloxy) -benzyl] -4- (Beta -D-glucopyranos-1-yl) -benzene (4) 1-methyl-2- (4-cyclohexyloxy-benzyl) -4- (Beta - D-glucopyranos-1-yl) -benzene (5) 1-chloro-2- [4- (1-tert-butyloxycarbonylpiperidin-4-yloxy) -benzyl-4- (beta -D-glucopyranos-1-yl) -benzene (6) 1-chloro-2- [4- (piperidin-4-yloxy) -benzyl] -4- (Beta -D-glucopyranos-1-yl) -benzene (7) 1-methoxy-2 - (beta -D-glucopyranos-1-yl) -4- (4-ethynyl-benzyl) -benzene (8) 1-chloro-2- (4-benzyl-metoximetiletinil) -4- (Beta -D-glucopyranos -1-yl) -benzene (9) 1-chloro-2- (4-benzyl-hidroximetiletinil) -4- (Beta -D-glucopyranos-1-yl) -benzene (10) 1-chloro-2- (4-hidroxietiletinil-benzyl) -4- (Beta -D-glucopyranos-1-yl) -benzene (11) 1-ethynyl-2- (4-methoxybenzyl) -4- (Beta -D-glucopiranos- 1-yl) -benzene (12) 1-methyl-2- (4-butyn-1-yl-benzyl) -4- (Beta -D-glucopyranos-1-yl) -benzene (13) 1-chloro -2- (4-propyn-1-yl-benzyl) -4- (Beta -D-glucopyranos-1-yl) -benzene (14) 1-methyl-2- (4-propyn-1-yl-benzyl ) -4- (Beta -D-glucopyranos-1-yl) -benzene (15) 1-isopropyl-2- (4-ethynyl-benzyl) -4- (Beta -D-glucopyranos-1-yl) -benzene , (16) 1-chloro-2- (4-benzyl-isopropiletinil) -4- (Beta -D-glucopyranos-1-yl) benzene, or a derivative thereof in which one or more hydroxyl group beta-D-glucopyranosyl group are acylated with between selected (C1 - 18) alkoxycarbonyl, (C1 - 18) oxycarbonyl, phenylcarbonyl and phenyl- (C1 - 3) alkoxycarbonyl, or a pharmaceutically acceptable salt thereof; including the tautomers, the stereoisomers thereof or mixtures thereof and salts thereof.

Term

No projected expiry on record.

  1. Priority
  2. Filed
  3. Granted
  4. Today

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Priority claims
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05002628European Patent Office (EPO)A

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US2005209166A1United States of AmericaA1
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