1-amino-2-oxy-substituted tetrahydronaphtalene derivatives, methods for the production thereof, and their use as antiphlogistics

Compounds of general formula (I), (See formula) wherein R 1 and R 2 independently of one another, mean a hydrogen atom, a hydroxy group, a halogen atom, an alkyl group (C1-C10) optionally substituted, a (C1-C10) alkoxy group optionally substituted, an alkyl (C1-C10) group alkylthio, a perfluoroalkyl group (C1-C5), a cyano group, a nitro group, or R 1 and R 2 in common mean a group selected from the -O- (CH2) not- -O- (CH2) n-CH2-, -O-CH = CH, groups - (CH2) n + 2, NH- (CH2) n + 1-, -N (C1-C3) - (CH2) n + 1, -NH-N = CH-, where n = 1 or 2 and the oxygen atoms and / or carbon atoms being bonded and / or nitrogen atoms, at the ends, with carbon atoms directly adjacent ring, or mean NR 8 R 9, can R 8 and R 9, independently of one another, be hydrogen, C1-C5 alkyl or (CO) - C1-C5 alkyl, R 11 means a hydrogen atom, a hydroxy group, a halogen atom, a cyano group, an alkyl group (C1-C10) optionally substituted, an alkoxy group (C1-C10), an alkyl group ( C1-C10) alkylthio, a (C1-C5) perfluoroalkyl group, R 12 means a hydrogen atom, a hydroxy group, a halogen atom, a cyano group, an alkyl group (C1-C10) optionally substituted, a group (C1-C10), R 3 means an alkyl group C1-C10 optionally substituted with 1-3 hydroxy groups, 1-3 halogen atoms or alkoxy groups (C1-C5), cycloalkyl group (C3-C7) optionally substituted a heterocyclyl group optionally substituted, an aryl group optionally substituted, a heteroaryl group mono- or bicyclic, optionally substituted by one or more groups chosen, independently of one another, from alkyl (C1-C5), which in turn may be optionally substituted with 1-3 hydroxy groups or 1-3 COOR 13 groups, where R 13 is hydrogen or (C1-C5), alkoxy groups (C1-C5), halogen atoms, hydroxy groups, NR 8 R 9 groups exomethylene, oxygen, optionally containing 1 to 4 nitrogen atoms and / or 1-2 oxygen atoms and / or 1-2 sulfur atoms and / or 1-2 keto groups.