Process for producing 5-substituted oxazole and 1,5-disubstituted imidazole compounds

The invention relates to a preparation method of the agricultural, medicine, the Functional material or intermediates useful heterocyclic compound. A wherein TosMIC and aldehyde or medicines compound (1 )in the non-proton solvent and protonic the mixed solvent and a base with the reaction; (2 )is the catalyst and inorganic alkali with the reaction; or (3 )in the application of the reaction, wherein in step a irritating mass and unstable, the decomposition temperature, and a explosive TosMIC, the solution is uniformly to obtain the lower any.