AT287413T

Method for preparation of lna phosphoramidites

Abstract

The present invention 2* シアノ ethyl *N, N, N, and N* tetra substitution ホスホラミダイト and a nucleophilicity activating agent, For example, it is related with the manufacturing process of the extensive scale of LNA ホスホラミダイト using 2* シアノ ethyl *N, N, N, and N* tetra-isopropyl ホスホラミダイト and 4, and 5* ジシアノ imidazole. This method is more efficient quickly and in cost than in the conventional well-known method. [化 1]

Term

No projected expiry on record.

12 members in 7 offices

This recordMember, by publication datePriority claim

Priority claims8

Priority claims
Document	Office	Kind	Date
PA200101095	Denmark	A	2001-07-12
PA200101095	Denmark	A	2001-07-12
0200488	Denmark	W	2002-07-12
0200488	Denmark	W	2002-07-12
200101095	–	–	–
0200488	–	–	–
DK2001PA01095	–	–	–
WO2002DK00488	–	–	–

Members12

Family members, oldest first
Document	Office	Kind
WO03006475A2	World Intellectual Property Organization (WIPO)	A2	2003-01-23
AU2002328792A1	Australia	A1	2003-01-29
WO03006475A3	World Intellectual Property Organization (WIPO)	A3	2004-02-26
EP1409497A2	European Patent Office (EPO)	A2	2004-04-21
JP2004536125A	Japan	A	2004-12-02
EP1409497B1	European Patent Office (EPO)	B1	2005-01-19
AT287413TThis record	Austria	T	2005-02-15
ATE287413T1	Austria	T1	2005-02-15
DE60202681D1	Germany	D1	2005-02-24
DK1409497T3	Denmark	T3	2005-05-30
DE60202681T2	Germany	T2	2006-01-12
JP4402454B2	Japan	B2	2010-01-20