Methods and compositions for synthesis of long chain polyunsaturated fatty acids

The invention relates to a method for the catalytic with the γ - linolenic acid to the arachidonic acid the fatty acid △5 - dehydrogenase. A phenol novolac a △5 of the nucleic acid sequence of dehydrogenase, capable of the nucleic acid sequence and △5 of the dehydrogenase gene structure DNA, and is processed by the expression △5 dehydrogenase the recombinant host microorganism or animal is a hybridizes. A phenol novolac is wherein the fatty acid in the △5 the position is of the unsaturated and method for by the expression level high - △5 dehydrogenase a method for arachidonic acid, provides a is - △5 dehydrogenase of the recombinant host microorganism or animal is a composition to the unsaturated fatty acid and containing of fatty acid oil. A pharmaceutical comprising a is - △5 dehydrogenase of the recombinant host microorganism or the animal is a composition to the unsaturated fatty acid or the composition and buffer formulated foods or its foods.