Composite synthetic peptide construct eliciting neutralizing antibodies and cytotoxic t lymphocytes against hiv

[Subject] Offer of the peptide which induces T helper response, a cytotoxic lymphocyte response, and a counteractive antibody in two or more hosts. [Solution means] The peptide structure containing the multiplex determinant site T helper peptide originating in the envelope protein of HIV, It is the polypeptide possessing the peptide 18 in V3 loop of HIV*1 and gp160 it is indicated to be that correspond to the main counteractive determinant site of HIV-IIIB, and a superior CTL epitope is included, Each response arises in two or more individuals of a mammals kind which present an extensive transplantation antigen haplotype. [Selection figure] Nothing