WO0202746A3

Coiled-coil mediated heterodimerization functional interaction trap

Abstract

Fusion proteins comprising coiled-coil heterodimerization domains substituted for modular protein binding domains useful for validating functionally relevant protein-protein interactions, directing enzymes to specific substrates, and screening fusion libraries for functionally important interaction partners.

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No projected expiry on record.

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Every citation, both waysCites: the store holds 1 of 2

Citations
DocumentRelationOfficeCategoryCited during
US2002037999A1CitesUnited States of AmericaXPInternational search
TRIPET ET AL: "Engineering a de novo-designed coiled-coil heterodimerization domain for the rapid detection, purification and characterization of recombinantly expressed peptides and proteins", PROTEIN ENGINEERING, vol. 9(II), November 1996 (1996-11-01), pages 1029 - 1042, XP002125681Non-patentInternational search
ARNDT ET AL: "A heterodimeric coiled-coil peptide pair selected in vivo from a designed library-versus-library ensemble", J. OF MOL. BIOL., vol. 295, 2000, pages 627 - 639, XP002156489Non-patentInternational search