Stretch resistant vaso-occlusive coils

Anti-extension vascular occlusion coil

Related applications

This case is a CIP application for U.S. Patent 08/717,285 (application date of September 20, 1996), and it is U.S. Patent 08/607,593 (application date of February 27, 1996) and U.S. Patent 08/ 497,331 (application date of June 30, 1995) CIP applications. Attach the complete content as a reference.

The present invention is an implantable vascular occlusion device. It is a typical vascular occlusion coil, which contains a main spiral bending coil, which can be bent into a secondary shape later. The core of the present invention is the use of a stretch-resistant article expanding onto the formed cavity. The stretch-resistant article can be directly or indirectly fixedly attached to at least two positions of the coil. It is better to put the stretch-resistant article in the cavity with a little slack to prevent the coil from collapsing and tying, and becoming stiff when passing through turns in the human body. This coil should be able to bend easily. In some variations of the present invention, the stretch-resistant article can use simple equipment, such as soldering iron or the like, to form a coil end cap on the end of the coil. The end cap has basically the same diameter as the coil body. The main purpose of the stretch-resistant article is to prevent the coil from stretching when the coil is moved, such as recovery or repositioning after an unfolding operation. The device has a self-formed secondary shape formed from a preformed main straight helical curved coil, although the secondary shape is not necessarily required. We hope that the coil is very flexible and can be released under control by using a separate or mechanical bonding point (such as a bond point that can be separated from the electrolyte). External fibers can be attached to the device and fixed to the pre-shaped linear article to increase blood clots. The extremely elastic changes of the present invention can be transmitted to the catheter cavity in a hydraulic manner, and it is so elastic that it can be restored to delivery by the flow-guided catheter. The vascular occlusion article can also be covered with a fiber tape. This device basically uses a catheter to be introduced into the human body. The device is passed through the catheter sheath in a shaft, and it is assumed that its secondary shape is located on the existing catheter.

The vascular occlusion device is surgically operated or implanted into the human vascular system, especially through a catheter, through the formation of a plug-like nucleus to repair the vascular system to block blood flow through the blood vessel, or form from the hemangioma trunk of the blood vessel. The plug-like nucleus. A widely used vascular occlusion device contains a spiral coil of winding, the space of which can be divided to set the blood vessel wall. Other less rigid helical coils and devices containing woven ribbons have been discussed. In fact, all of these vascular occlusive implants are delivered by a coil-guided catheter, and the device is pushed into the catheter. Due to the need for a pusher, and considering the recovery of this vascular occlusion device after being misplaced in the body, the present invention is different from the previously existing vascular occlusion device that is delivered by a flow-guided catheter.

An early case of a vascular occlusion device, namely, US Patent 4,004,069 to Richart et al., discloses a vascular occlusion coil that assumes a linear spiral structure when stretched, and a folded spiral structure when relaxed. The stretched condition is used to place the coil in the desired position (by passing through the catheter), and the coil assumes a loose structure-once the device is installed, it is more suitable for blocking Blood vessel. Ritchart et al. have disclosed many shapes. The secondary shapes of the disclosed coils include the "flower" shape and the double spiral shape, which are also described in the random secondary shape specification.

U.S. Patent No. 5,304,194 to Chee et al. discloses that there are attached fibrous elements on vascular occlusion coils of various minor shapes. Chee et al. described a spiral bending device with a secondary shape in which the fiber elements are stretched sinusoidally to the length of the coil. The coil and the coil disclosed by Ritchart et al. are manufactured in this way so that they can pass through the catheter lumen in a general linear configuration, and when released from the catheter they can be in the cavity of the human body's choice Form a relaxed or folded shape. The fiber element disclosed by Chee et al. can enhance the function of the coil so as to fill the space in the blood vessel system, and help the plug-like nucleus to form and finally integrate with the tissue.

There are many ways to release shaped coils and straight coils into the blood vessel system of the human body. In addition to those patients who clearly stated that they only use the body to push the coil out and enter the vascular system (such as Ritchard et al.), there are many other ways to release the coil at a specific selected time and location. U.S. Patent No. 5,354,295 and its parent case, No. 5,122,136, disclosed by Guglielmi et al., both illustrate a plug device with separable electrolyte.

There are many types of mechanically detachable devices that are well known. For example, US Patent No. 5,234,437 to Sepetka discloses a method of bending a coil from a surface-attached thruster without twisting the spiral. Palermo's US Patent No. 5,250,071 discloses an embolic coil combination using a connecting hook mounted on the pusher and embolic coil. Engelson's US Patent No. 5,216,916 discloses a detachable thruster-vascular occlusion coil combination with a connecting ball and a lock groove type combination. U.S. Patent No. 5,304,195 to Twyford et al. discloses an extension cord attached to the base, which carries a ball on the end of the base and has a propeller-vascular occlusion coil combination similar to a propeller at one end. The two ends are joined together and can be detached when ejected from the distal tip of the catheter. Palermo's US Patent No. 5,312,415 also discloses a method of removing many coils from a thruster by using a guide wire, which has a cross section that can connect to each other inside the spirally bent coil. U.S. Patent 5,350,397 to Palermo et al. discloses a thruster with a narrow passage at the distal end and a thruster leading to its shaft. The pusher sheath grabs the tip of a plug-like nucleus, and then is released when the wire placed on the shaft pusher is pushed to the item found at the proximal end of the vascular occlusion coil.

Vessel occlusion coils with minor shapes that were not previously available have also been revealed. For example, US Patent 07/978,320 filed by Berenstein et al. on November 18, 1992, entitled "Super soft plug-like nucleus coil with liquid-like properties", found that a kind of coil produced very little when introduced into the vascular space. There is not even a shape.

None of the above-mentioned devices contains a helical coil of a stretch-resistant article.

The present invention is a blood vessel occlusion device, which includes a spiral bending coil formed by bending a wire into a first or main spiral to produce a spiral article having first and second end points . The stretch-resistant article is stretched to the cavity, and the article formed in this way is directly or indirectly fixedly attached to at least two positions of the coil. The stretch-resistant article should preferably be loosened inside the coil to prevent the coil from tying when the coil passes through the turn of the blood vessel system.

The primary spiral shape can be bent into a secondary shape, and can be heat treated to maintain this shape, preferably before the step where the stretch-resistant article enters the coil. The secondary shape may be a special shape that should be excluded from the delivery conduit. This shape can fill the vascular cavity, such as a hemangioma, perhaps a tube or AVM. The stiffness of each part of the coil can be adjusted to improve the use of the device for special applications. This device requires a very flexible coil, and the fiber material can be woven into the article or tied or wound on it to increase blood clotting.

If necessary, the device is only used temporarily to straighten the device and introduce it into a suitable catheter, which is already suitable, so that its distal opening is located at a selected part of the body. When excluded from the distal end of the catheter into the vascular cavity, the device is then pushed through the catheter assuming it is slack or a secondary shape.

The device is basically used in the vascular system of the human body to form a plug-like nucleus, but it can be applied to any part of the body where the blood vessel is blocked, so the device of the present invention is required.

At the same time, the present invention also produces an important concept, that is, the combination of the vascular occlusion device of the present invention and the flow-guided catheter.

Figures 1A, 1B, and 1C show side views of partial cross-sections (or cut-away portions) of extremely satisfactory variations (100, 200, 210) of the coil of the present invention. The variation shown in Figures 1A and 1B is composed of a spirally bent outer coil (102, 202), which has a first end (104, 204) and a second end (106, 206) . We refer to this shape as the "first" bend or shape. These changes include a stretch-resistant article (108, 208, 214), which is shown to be fixedly attached to the first end (104, 204) and the second end (106, 206). In some cases, it can satisfactorily attach the stretch-resistant article (108, 208) to only one of these two endpoints, or at least a position between these two endpoints, or Both ends are not required. Obviously, in order to maintain the stretch resistance, the stretch-resistant article must be attached to at least two points on the coil.

Another variation of the stretch-resistant article (108) shown in Figure 1A is fiber and a satisfactory polymer. The stretch-resistant article (108) can be thermoplastic or thermosetting, and contains a bundle of fibers or a single fiber that is melted, adhered, or fixedly attached to the vascular occlusion coil (100) in other ways. In some cases, it may also be desirable to include one or more metal wires on the stretch-resistant article (108) in order to provide rigidity or conductivity for special applications.

Another variation of the tensile article (208) shown in Figure 1B is a simple wire or "ribbon" which is soldered, brazed, glued or otherwise fixedly attached to the first end ( 204), the second end point (206), or the coil located at one or more positions in the middle of those end points.

The variation shown in Figure 1C includes a stretch-resistant article (214), which includes a spiral bending coil that is soldered, brazed, glued or otherwise fixedly attached to the first end (204) Or the second end point (206) or in one or more centered positions. The stretch-resistant article (214) of this structure has wider side elasticity than the change of the wire (208 in FIG. 1B). It can be bent in the same direction or another direction as the outer coil (202). The most conservative weakness of this change is that when the shaft is compressed, it will stretch more than the change in Figure 1B.

The material of the vascular occlusion coil (102, 202) and the stretch-resistant article (108, 208, 214) can be any of various materials; preferably radiopaque materials, such as metal or polymer materials. Suitable metals and alloys used to make the main coil (102, 202) wires and the tensile articles (108, 208, 214) include platinum group metals, especially platinum (platinum), rhodium, palladium, rhenium and tungsten, gold , Silver, tantalum, and these metals and alloys. These metals have obvious radiopaque properties, and their alloys can be used for adjustment to complete the appropriate blend of elasticity and stiffness. They are also biologically inert. The best example is a platinum/tungsten alloy, where the content of tungsten is 8% and the rest is platinum.

The ribbon or coil type stretch-resistant article (208, 214) can be any type of stainless steel, assuming that some opaque loss and elasticity can be tolerated. From a mechanical point of view, although limited by high pressure, satisfactory manufacturing materials are those that can maintain their shape. Some "super-elastic alloys" include various nickel/titanium alloys (nickel contains 48-58 atomic percent, or a small amount of iron can be blended); copper/zinc alloy (zinc contains 38-42 weight percent); contains 1-10 weight Percentage of copper/zinc alloy of beryllium, silicon, tin, aluminum or gallium; or nickel/aluminum alloy (aluminum contains 36-38 atomic percent). Particularly good examples are disclosed in U.S. Patent Nos. 3,174,851, 3,351,463, and 3,753,700. A preferred example is a titanium/nickel alloy, which is commonly known as "Nitinol". The above-mentioned are all very strong alloys, which can withstand significant elasticity without deformation, and can even be used as wires with very small diameters.

Assuming that a superelastic alloy such as Nitinol is used in the device, the wire diameter of the coil may be significantly smaller than the diameter of the more ductile platinum or platinum/tungsten alloy used as the manufacturing material.

The coil can be made of radioluminescent fibers or polymers (or coated with radioluminescent metal fibers or radiopaque fibers), such as Dacron (a trademark for polyester fibers), polyglycolic acid, and polyglycolic acid. Lactic acid (Polylactic acid), Fluoropolymers (Polytetrafluoroethylene), Nylon (Polyamide), and even cotton or silk materials. The polymer should be used as the main component of the vascular occlusion coil, and it is expected to be filled with some radiopaque materials, such as titanium powder, tungsten powder, bismuth oxide, barium sulfide, and similar materials.

The material of the coil is first bent into the main coil (102, 202), which is substantially straight after being bent. Generally speaking, when the coil (102, 202) is a metal and a platinum alloy or a superelastic alloy, such as Nitinol, the diameter of the wire used to make the coil (102, 202) is 0.00025 as the main coil The main diameter of the wire is 0.003. For the symptoms of disease, the ideal main coil (102, 202) diameter is 0.008 to provide the strength of the steel belt of the final device, and the selected position in the body, such as the cavity to support the device, It does not substantially expand the cavity wall, and it does not move from this position as a result of the repeated liquid arteries found in the vascular system. However, the concept of the present invention allows the user to use a coil combination that is extremely flexible and has a high coating efficiency. For example, a coil wire with a diameter of no more than 0.0005 inches is suitable for this highly flexible device. Basically, the diameter of the coil is no more than 0.015 inches. They can be tilted more than 20. When 1 cm of the main shape of the coil has a free end to keep horizontal, the preferred angle is 35~90.

The shaft length of the main coil usually ranges from 0.5 to 100 cm, generally 2.00 to 40 cm. Depending on the use situation, the coil can have 10 to 75 turns per centimeter, preferably 10 to 40 turns per centimeter. All the dimensions presented here are for reference only, and are not important decisive factors for the present invention. However, only the size suitable for the occluded position of the human body is included in the scope of the present invention.

Once the main coil is bent, the stretch-resistant article (102, 202) will be embedded in the cavity of the main coil (102, 202), and the coil will remain as it is. The other ends (104, 204, 106, 206) preferably have the same diameter as the main coil (102, 202).

Suitable polymer materials for polymer stretch-resistant articles (108) can be thermosetting or thermoplastic materials, preferably thermoplastic materials, because they can melt and form the end points (104, 106), so they can To simplify the manufacturing process of the device, a simpler device such as a soft soldering iron can be used to form the end point. Thermosetting plastics can basically be glued and fixed in place. Suitable polymers include most of the biocompatible materials that can be made into fibers, and include thermoplastic materials, such as Polyester (Polyethyleneterephthalate) (PET), especially Dacron ; Polyamides include nylon (Nylon); polyolefins such as polyethylene, polypropylene, polybutylene, their mixtures, alloys, blocks and any copolymers ; Polyglycolic acid; Polylactic acid, Fluoropolymers (Polyt etrafluoro-ethylene)); or silk materials. Since it needs to be placed in the human body for a long time and safety and effectiveness are considered, the preferred materials are fibrous PET (trade name Dacron) and polypropylene (Polypropylene), especially polypropylene (Polypropylene) is the best.

Fig. 2A shows a side view of the end of the coil (100) of the present invention partially cut away. Figure 2A also shows that the spirally bent outer coil (102) has an end point formed by the previously melted fiber, and the stretch-resistant article is also composed of it. This type of endpoint can be considered to have appropriately higher vascular occlusion characteristics than the metal endpoint. Others that have the same function for this structure include the end point formed by the peroxide or the adhesive of the same material, and its mechanical properties.

Figure 2B shows a node (112) that fixes the length of the coil article (102) and keeps it from stretching its outer surface; Figure 2C shows a reshaped mass composed of previously melted polymers or adhesives, the diameter of which is greater than The coil (102) has a large internal diameter and can prevent the coil from stretching. The node (112) and the block (114) are not shown attached to the coil (102) but may be attached to it.

The variations shown in FIGS. 1A, 1B, 1C and 2A, 2B, 2C are designed to deploy operations by using a propeller and catheter, and using the method previously discussed in the patent disclosed by Ritchart et al. Other methods (and accompanying devices or connections to accomplish these methods) may also be used.

For example, the end point of the device can be adapted to accept one of the types previously discussed in U.S. Patent No. 5,354,295 and its parent case 5,122,136, where the electrolyte can be separated, the inventors of these two patents are Guglielmi and Sepetka, respectively. Figures 3A and 3B illustrate these changes in partial cross-sections. The vascular occlusion coil (130, 230) is attached to a filled article or bushing (132, 232). The filled article or bushing (132, 232) preferably includes a thermoplastic or peroxide or similar material formed at its location, and the two are respectively adhered to the tensile article (134, 234) and the coil On the wires (136, 236). The stretch-resistant article (134, 234) is thus indirectly attached to the vascular occlusion coil (130, 230) via the filled article or bushing (132, 232). In this variation, the wire (136, 236) of the coil has an elongated object hidden in the filled object (132, 232). Basically, the wire (136, 236) of the coil uses polytetrafluoroethylene (Polytetrafluoroethylene) and a thermoplastic polymer film (PARYLENE, Polyparaxy) made of paraxylene. The mixture of xylene) is insulated. When the connection point (138, 238) is corroded or separated and the coil deployment operation enters the proper position of the human body, except for a small piece of loss, the connection point (138, 238) is expected to be regarded as electrolysis Location. The details of this change (without stretch-resistant articles (136, 236)) are discussed in US Patent Application No. 08/367,061 disclosed by Gia et al. on December 30, 1994, and the full content of the description is attached for reference.

Figure 3C shows a particularly ideal variation of the device of this invention. The combination (131) uses a tensile article (133) indirectly connected to the coil (135). In particular, the stretch-resistant article (133) is a thermoplastic fiber or is melted to form a coil end cap (137) at one end of the coil (135) and at the other end (or at the other end of the coil (135)). Nearby) form a loop hook (139). A support coil (141) is located coaxially between the vessel occlusion coil (135) and the pusher wire (136). The hook (139) generates the last turn or half turn of the support loop (141). The stretch-resistant article is thus indirectly attached to the vascular occlusion coil (135) by the support coil. The support coil (141) and the blood vessel occlusion coil (135) are preferably welded together.

Fig. 3C also shows that the vessel occlusion coil (135) is in a state of maximum extension. The stretch-resistant article (133) shows that the combination further resists the stretching of the axis. When the vascular occlusion coil (135) is not stretched, the stretch-resistant article (133) will be significantly looser in the cavity of the combination (131), that is, it is longer than the cavity. If the stretch-resistant article (133) does not allow such a loose shaft joint body, when passing through the turn of the blood vessel system, the nearby turns of the coil (135) will fall between each other, and cause the combination (131) Become stiff.

Figure 4A still shows a change in the junction to release the coil of the invention into a proper position in the human body. In this example, the junction is a mechanically unfolding operation. The main coil (140) is combined with the connecting hook, one (142) is located at one end of the (140) and the other (144) is located at one end of the pusher (146). The stretch-resistant article (148) is attached to the connecting hook (142) by a filling block (154). Moreover, the filling block (154) contains a material (such as a thermoplastic or adhesive material) that can be placed on the coil and adheres to the stretch-resistant article (148). The coil assembly (150) composed of the main coil (140), the connecting hook (142) and the stretch-resistant article (148) is deployed by contracting the catheter body (or catheter sheath (152)). Figure 4B shows a variation of the device illustrated in Figure 4A, which does not use a special filler material (154) to adhere to the stretch-resistant article.

Other mechanically unfoldable joints suitable for the use of the coil of the invention are described as follows: 1. Sepetka's US Patent No. 5,234,437 discloses a method of loosening a spirally curved coil from a thruster with a connecting surface.

2. Palermo's US Patent No. 5,250,071 discloses an embolization assembly that uses a connecting hook frame to be placed on the pusher and the embolization coil.

3. US Patent No. 5,261,916 disclosed by Engelson discloses a detachable thruster-vascular occlusion coil combination with a connecting ball and a lock groove type combination.

4. US Patent No. 5,304,195 to Twyford et al. discloses an extension cord attached to the base, which carries a ball on the end of the base and has a propeller-vessel-occluded coil combination similar to a propeller at one end. The two ends are joined together and can be detached when ejected from the distal tip of the catheter.

5. Palermo's US Patent No. 5,312,415 also discloses a method of removing many coils from a pusher by using a guide wire, which has a cross section capable of interconnecting the inside of the spirally bent coil.

6. U.S. Patent 5,350,397 to Palermo et al. discloses a thruster with a narrow passage at the distal end and a thruster leading to its shaft. The pusher sheath grabs the tip of a plug-like nucleus, and then is released when the wire placed on the shaft pusher is pushed to the object found at the proximal end of the vascular occlusion coil.

Attach the complete content as a reference.

As mentioned above, the device of the present invention may have a simple linear shape as shown in FIGS. 1 and 2 or a shape that is not so simple. Figures 5, 6 and 7 show that the term "secondary" shape comes from the primary coil bending the primary coil in the desired shape in a simple manner, and then heat-treating the formed shape. Figure 5 shows a "C"-shaped coil assembly (160) containing a stretch-resistant article (162). Figure 6 also shows a clover leaf coil assembly (164) containing a stretch-resistant article (162). Figure 7 shows a combination of double loop coils (166). The above figures are all descriptions of various secondary shapes suitable for the present invention.

In addition, these inventive devices can be used to connect with external fiber appendages. Figure 8 shows a partial side view of a linear variation of the device of the present invention with a single fiber material (172) passing through the coil (174). This more detailed attachment method is described in U.S. Patent Nos. 5,226,911 and 5,304,194 disclosed by Chee et al., and the entire contents of the description are attached for reference. A desired fiber attachment method is further described in Mirigian et al. in US Patent Application No. 08/265,188 on June 24, 1994.

Figure 9 shows a partially cut-away view of the device (180) with a single-fiber material webbing and a stretch-resistant article (184). This method of covering the coil is described in more detail in U.S. Patent No. 5,382,259 disclosed by Phelps et al. The complete content of the description is attached for reference.

The material of the thin tube woven or decorated with ribbons can be made of biocompatible materials such as Dacron [polyester], polyglycolic acid, polylactic acid, and fluorinated polymer. (Polytetrafluoroethylene) (Fluoropolymers (Polytetra fluoroethylene)), nylon (polyamide) (Nylon (Polyamide)), or silk materials. The twists that form the ribbon should have a reasonable weight, that is, have a tensile strength greater than about 0.15 pounds. To some extent, the material mentioned can be thermoplastic, which can melt or fuse into the coil. Alternatively, they can be glued or otherwise fastened to the coil. A preferred material includes Dacron.

Figure 10 shows a highly ideal combination of many concepts expected by the present invention, especially the previously mentioned vascular occlusion device of the invention is very flexible, for example, the vascular occlusion device can be "tilted" 20 or more A stretch-resistant article that is large and has a polymer as described above is particularly suitable for including a flow-guiding conduit, and is particularly suitable when an electrolyte can be separated from the junction point. Figure 10 shows the flow-guided catheter (200) containing the elastic vascular occlusion coil (202) as described above and using a similar elastic anti-tension article (204). If required, the flow-guided catheter (200) may have a distal radiopaque note (206).

At the base of the vascular occlusion coil (202) is a connecting wire (208), which is insulated at all points of the base of the electrolytic connection point (210).

The flow guiding catheter (200) may be of a known design, which is disclosed in US Patent No. 5,336,205 by Zenzen et al. The full content of the description is attached for reference. The "flow-guided catheter" is guided by the motive force of blood flow into the treatment site of the human body through the blood vessel system. The more distal part of the flow guiding catheter is a commonly used material, which has obvious elastomer properties but high explosive strength, such as polyurethane, polyvinylchloride and silicon (Silicones) and so on. These materials feel very elastic. Therefore, flow-guided catheters are generally not suitable for the use of wires or similar materials.

However, when using the change of the vascular occlusion device, since the vascular occlusion device is very convenient to use and can only be delivered by water pressure (such as using physiological saline), it can use a flow-guided catheter. Furthermore, since the vascular occlusion device (202) includes an anti-stretch article (204), the vascular occlusion device (202) can be retracted into the catheter using the connecting wire (208).

The connecting wire (208) used here should be very flexible so as not to interfere with the movement of the catheter (200). The base of the electrolytic connection point (210) is conductive and insulating. The introduction of current into the connecting wire (208) will cause the electrolytic connection point (210) to corrode and the vascular occlusion device (202) to separate. The complete operating instructions for this device are disclosed in Guglielmi and Sepetka's U.S. Patent Nos. 5,122,136 and 5,354,295.

Figures 11A-11D illustrate a general method of deployment operation to introduce the inventive vascular occlusion device described herein. We can observe that these steps are not significantly different from those described by Ritchard et al. In particular, Fig. 11A shows that the distal end of a delivery catheter (310) is short, which is located inside the opening of the hemangioma of the artery. The distal or top part of the vascular occlusion device is displayed inside the catheter. In Fig. 11B, the distal end of the vessel occlusion device (318) exits the distal end of the catheter (310) and is bent into a primary shape inside the hemangioma. Figure 11C shows the completion of the formation of this secondary shape in the hemangioma (314). Figure 11D shows the separation of the vascular occlusion device (318) from the pusher, its replacement in the hemangioma (314), and the exit of the catheter from the exit of the hemangioma (314).

Once the coil of the invention is placed in a hemangioma or other location, a situation occurs when the coil must be moved or even withdrawn. For example, in Figure 11D the coil may be extended through the exit of the hemangioma and into the artery. The arteries do not want to be blocked. US Patent 5,387,219 disclosed in Rappe shows a device similar to a trap inside a blood vessel, which can be used to grasp an exposed coil and move it or restore it from the body. The stretch-resistant article of the present invention can prevent the coil from stretching to a single strand of wire and enlarge the length.

The modification to implement the above-mentioned changes of the invention is obvious to those who are familiar with the technical field of the medical instrument design, especially the anti-vascular occlusion device, which is generally intended to include the following application scope.

Figure 1A. A side view of a partial cut away of a vascular occlusion coil made of a general linear fiber stretch-resistant article according to the present invention

Figure 1B. A side view of a partially cut away blood vessel occlusion coil made of a stretch-resistant article containing a general linear wire according to the present invention

Figure 1C. A side view of a partial cut away of a vascular occlusion coil made of a general linear spiral stretch-resistant article according to the present invention

Figures 2A, 2B, 2C. Side views showing the typical end points of the vascular occlusion coil of the present invention partially cut away

Figures 3A, 3B, 3C. Cutaway side views of the separable junction point of the electrolyte made according to the present invention and the blood vessel occlusion coil connected together

4A, 4B. The side view of the partly cut away of the point-type mechanically separable joint made according to the present invention and the vascular occlusion coil connected together

Figure 5. Shows the minor shape of the "C" shape of the vascular occlusion device of the present invention

Figure 6. Shows the secondary shape of the clover leaf shape of the vascular occlusion device of the present invention

Figure 7. Shows the secondary shape of the double ring of the vascular occlusion device of the present invention

Figure 8. Shows that the outer fibrous material is attached to the vascular occlusion device of the present invention

Figure 9. Shows that the outer fiber tape material is attached to the vascular occlusion device of the present invention

Figure 10. Shows the combination of the vascular occlusion device of the present invention and the flow-guided catheter

Figures 11A-11D. Show the steps of introducing the vascular occlusion coil shown in other figures into a hemangioma.