Medicine inholating device

(54) Device for inhalation of medicines

The invention relates to a device for inhaling medicines in the form of powder or liquid, namely, for treating respiratory diseases, such as, for example, bronchitis or rhinitis.

Devices for inhalation of medicines using a spray with compressed air, hot steam or drive gases are known, with drug aerosols being inhaled. However, these known devices have the disadvantage that most of the drug does not reach the airway. As a result, an exact dosage of the drug is not possible. In addition, these devices for inhalation of drugs have the disadvantage that a considerable part of the drug reaches the gastric tract, is resorbed there and can cause unwanted side effects, and by using the training gases the whole body is required extra.

In order to avoid these shortcomings, devices have been designed for inhalation of powdered medicines »at which the drug can only be sprayed, when the patient absorbs air through the device containing the drug and (73) Holder:

Schering Aktiengesellschaft, Berlin Vest (BW)

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These pre-known devices! moving parts, most OrTin in the form of propellers, driven by the absorbed air, which produce a spray of the drug in the form of powder. By using these devices, it can be achieved, to a large extent, that the powdered drug can reach the rejects. Also, these known devices have a number of disadvantages, in that a considerable part of the suction air is used to move the moving parts of the device that serves for spraying and the patient must inhale heavily during inhalation, which often causes considerable inconvenience. It is then inevitable that, during inhalation, a portion of the powdered drug will not remain on the moving parts of the device, so exact dosage of the drug becomes difficult. In addition, the construction of these devices, provided with movable parts, is relatively expensive. In addition, known devices have the disadvantage that only powdered medicines that are in perforated capsules can be used in them and that in these devices ·; that is, only then can a release be obtained

On a sufficient Thursday of the drug when it has a sufficiently granular size, in addition, they are not suitable for micronized or liquid powders.

The device for inhaling the medicines according to the invention eliminates these disadvantages, in that, in order to obtain the optimal spray of the drug, inhaling the medicines, both in the form of powders and liquids, whether or not encapsulated, without reaching the gastric tract, consists of a Venturi tube-shaped housing, provided with an inhalation nozzle and a container, which is used to receive the drug and a hole is used for draining, ending before the diffuser portion of the Venturi tube housing, the receptacle serving for receiving the drug being opened at both ends, and provided with a metering device, which is thus located on the Venturi tube housing, so that the hole, which serves to drain, of the metering device, ends before the diffuser portion, of the Venturi tube-shaped housing, which is composed of an open chamber at the front, and at the back it has an annular or pipe-shaped narrowing_r which, in turn, is linked to the inhalation nozzle, the funnel-shaped chamber being opened at the front, and the pipe-shaped receptacle is located between the chamber and the annular narrowing for taking the drug, also provided on the inside, with ribs or protrusions, a vessel used for taking the drug, and provided with a capillary outlet and a dosing device, which is provided with a container holder and rigidly connected to the Venturi tube housing, the container is also provided with two to twenty-four dosing spaces, between a container holder and the media container a movable dosing plate is placed, which it has one to twenty dosing spaces, and the application nozzle is provided with an application pipe, bent upwards, the nozzle widening in the form of a funnel and then. it narrows, having an elliptical or nearly rectangular orifice.

Further examples of execution of the device for inhalation of the medicines according to the invention are given in connection with FIG. 1 ... 16 which represents:

FIG. 1, side view of the device, enlarged twice;

FIG. 2, plan view of the device, without container, enlarged twice;

FIG. 3, a section, with a plane, I-I of the device of FIG. 1 ;

FIG. 4, bottom view of the disassembled container, enlarged twice;

FIG. 5, side view of the capture plate; FIG. 6, rear view of the capture plate;

FIG. 7, side view of another embodiment of the device, enlarged twice;

FIG. 8, the casing in the form of a Venturi tube, of another embodiment, provided with an inhalation nozzle and a support;

FIG. 9, the container of the device of FIG. 8;

FIG. 10 is a side view of another embodiment of the device;

FIG. 11, plan view of the device, the container being dismantled;

FIG. 12, a longitudinal section through another embodiment of the device;

FIG. 13, a longitudinal section through another embodiment of the device;

FIG. 14, longitudinal section, by another embodiment;

FIG. 16, longitudinal section, by another embodiment.

The device for inhaling the medicines according to the invention is composed of a housing A, in the form of a Venturi tube, which is provided with an inhalation nozzle and a container 1 for taking the drug, having a drainage hole before the diffuser portion of the housing A The container 1 may be provided with a dosing device 2.

In principle, the housing A of the device consists of two cones in the shape of a cone trunk, connected together at their tip, which form a chamber b and a piece in the shape of a funnel 3. between these coats there is an annular narrowing c, which can also be in * pipe form. Room b is connected, in turn, with the inhalation nozzle a.

The chamber b, open at the front, may be cylindrical, elliptical, spherical, pear-shaped or funnel-shaped. This room may have, at the front, one or more openings, which are so sized that the total opening of the room b has an area of ​​about 1 to 100 times larger than the smallest surface of the empty space of narrowing c. The chamber itself b has the maximum inner diameter, 2 to 10 times larger than the smallest inner diameter of the annular narrowing c.

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In order to obtain an optimal flow, chamber b is so constructed that it has a funnel shape towards the annular narrowing c.

the annular narrowing c, connected with chamber b, has a length of 1 to 20 mm and has, in the narrowest place, an inner diameter of 1 to 5 mm.

The inhalation nozzle a, in front of the annular narrowing, c, may have a pipe shape or an enlarged funnel shape to the outside. If the device according to the invention serves to apply the drug to the nostrils, then the nozzle is provided with an intermediate pipe 4, according to FIG. 10, removable, bent upwards, having a conical part 5, also removable, which has a shape suitable for nasal application.

If the device, according to the invention, serves to inhale drugs on the mouth, then the inhalation nozzle is formed in such a way that it widens into a funnel shape and narrows to the mouth like a cone trunk, so it is particularly advantageous to flatten it. the upper and lower part of the conical narrowing, so that the inhalation nozzle has an elliptical or almost rectangular opening. This special form of opening does the damage that the device uses, introduces its tongue irrespective of the inhalation nozzle, obtaining optimum inhalation.

The container b, which serves for the storage of the drug, may be provided with a dosing device 2, and which is so located on the housing A in the form of a Venturi tube, that the opening of the container 1, respectively of the dosing device 2, ends before the diffuser portion of housing A in the form of a Venturi tube.

In principle, it is possible to use in this device the thousands of different containers 1, provided with a dosing device 2, if they are provided with a container holder 6, which is rigidly connected to the housing A in the form of a Venturi tube and which has a drain hole, does it end before the diffuser portion of housing A, in the form of a Venturi tube. The shape of the container holder 6 »of the drug container 7 and the constructive parts of the dispensing device, which together form the container 1» which is used for the taking of the drug, depends on whether drugs are applied in powder form, or in the form of liquids.

Thus, the drug container 7 can be provided with 2 to 24 dosing spaces, are each loaded with a defined amount of a powdered drug and are fixed on the support 6, by ordinary means, in this way, so that by moving the container 7, each dosing space reaches above the drainage hole of the support, and the other dosing spaces are covered by the support 6, respectively by a cover plate 8, provided with a continuous hole positioned above the drain hole.

A container is used to take a powdered medicine, for example, it consists of the following component parts: drug container 7 is a cylindrical part, having cylindrical or conical holes d, which serve as a dosing space, which are removed 2 to 24 mm from the center of the cylinder and which serve as a dosing space and which are placed, together with a hole on the cylinder, symmetrical and central around the center of the cylinder.

These dosage areas are distinct and are so chosen that they allow the different doses of the drug to be given. The container 7 may be provided with a cover plate 8, rotatably disposed thereon and which is provided with an orifice, which allows the discharge of a dose of drug. This orifice is located at an equal distance from the center of the cover plate 8, equal to that of the holes d from the center of the container 7. In this form of the container 7 and the cover plate 8, the holder 6 of the container has an empty space, in which the container 7, together with the cover plate 8, can be inserted by rotation, and the cover plate 8 and the holder of the container are provided with devices such that they allow a cover plate 8 to be placed in the empty space of the support 6. Through the container holder a continuous hole passes inside the housing A in the form of a Venturi tube, which is so positioned that during the rotation of the container 7, it allows a dose of the drug to be emptied and is placed at an equal distance from the empty space at same as the one between the holes d and the center of the container 7.

The device described allows the application of a defined number of doses for a powdered drug. After completion of the application of the different doses, the empty container 7 should be replaced, at ηέvoie, by a new container filled with a medicine. By this, it is permissible * to apply certain drugs, the use of which would be questionable without an exact Control of the applied quantity.

If the device, according to the invention, is to allow the application of a small number of drug doses in the form of powder, without changing the cold of the drug, then to the container

- The drug bundle 7 can be made in the form of a bottle.

The drug container 7 may be linked to the support 6, which, in turn, is located on the housing A in the form of a Venturi tube, and the support 6 or container 7 is provided with a movable dosing plate 8, which contains 1 to 20. dosing spaces, and a lid 9, which closes the hole of the container, which are thus formed, reinforces, by moving the dosing plate 8, it can reach, under the lid 9, according to fig. 7 and 10, a dosing space being disposed over the drain hole of the support 10, and the other dosing spaces are closed by the support 6.

In another embodiment of the dosing device, according to the invention, it may be composed of the following component parts, which will be described below.

A drug container 7 is closed at its bottom with a lid 9, which has an orifice located away from the center of the lid. A movable shaft passes through the center of the container and is provided with a handwheel or agitator, which is rigidly connected to a dosing plate 8 below the lid 9, which has 1 to 20 dosing spaces, are evenly spaced from the center of the dosing plate 8, as well as the hole of the dosing plate from its center.

The holder of the container 6, with the surface of the shape of a washer, connected to the housing A in the form of a Venturi tube, has a drain hole, which serves for emptying, is it evenly removed from the center of the plate, with the dosing spaces from the center of the dosing plate 8. The container holder 6 or the drug container 7 additionally has ordinary auxiliary means, which allow the drug container 7 to be disposed in such a way on the container holder 6, and the dosing plate 8 to be placed on the surface in the form of the washer of the support 6 and the drain hole and the support and the hole of the lid are offset between them.

In another embodiment of the device for introducing drugs, according to the invention, the container holder 6, connected to the housing A in the form of a Venturi tube, has an upper part, with a pin fixed in the center and a drainage hole, which serves to drain. . On the pin is provided a dosing plate 8, which can be rotated and which is provided with 1 to 20 dosing spaces which are equally removed from the center of the plate, as well as the drainage hole from the center of the upper part in the form of a support plate. of container 6. The dosing plate 8 is provided with a support ring, on which the drug container 7 can be placed in a dose form. On the pin was fixed rigidly a lid, which is so formed, it covers a dosing space above the drainage hole.

The inhalation devices of the described drugs may be additionally provided with a pick-up plate 10, disposed in the annular narrowing c and under the emptying hole, which is thus formed, the drug exiting the emptying hole is supported by a pick-up plate. 10, even when the device is placed obliquely and at inhalation, the drug undergoes a pre-rumination, before it occurs later in the portion of the speaker. For this purpose, the capture plate 10 has a groove-shaped recess, in the longitudinal direction of the plate, and an anterior edge, which protrudes above the surface of the plate, forms with the lower part of the plate an angle of 30 to 120 °.

The inhalation devices of the described drugs may be provided, additionally, by ordinary auxiliary means, which cause the container 1 or the dosing plate 8 to stop each time during rotation, when a dosing space d is above the drainage hole. . The device for inhaling liquid media, in another embodiment, is composed of a housing A in the form of a Venturi tube, which is connected with a container holder 6, which has a cylindrical hollow space, which serves as a metering space, and a pipe-shaped drain hole, which corresponds to the support 6. With the aid of a support device, a container of medicines 7, made of elastic material, which is closed with a stopper, through which a hole in the form of a pipe, which corresponds to the empty space of the support 6, can be placed on the support 6.

On the other hand, the container 1, which is used for taking the drug, can be opened at both ends and placed in such a way, so that the hole that serves to empty the container is immediately in front of the diffuser portion of the housing A in the form of a Venturi tube.

This container 1 may be in the form of a pipe, funnel, cone or even and is provided at both ends with one or more holes. The constructive part may be provided, internally, with ribs, or projections, which is an advantage, especially when the device is used for the use of medicines in capsules.

Container 1, which is used for taking the drug, can be located in this way, since it is located between chamber b and the ring narrower c and is directly linked to the ring narrower c.

If container 1 serves to take the capsule drug, then it is sized so that it has an inside diameter that is 1.0 to 2.0 times the diameter of the capsule and has a length that is 0 , 5 up to 1.2 times the length of the capsule.

The container 1 for taking the drug, open at both ends, may be so formed that it is a funnel, which serves to take the drug and is provided with a capillary outlet, the drainage hole of which corresponds to the narrowing or immediately before the ring narrowing. .

The capillary outlet of the container 1 has an opening of 0.1 mm up to 2 mm. The outlet may be straight and the funnel, provided with a pipe-shaped nozzle, is located in the middle of the chamber and is connected to it by means of ribs.

On the other hand, the capillary outlet can be bent, and the funnel can be fixed laterally on the wall of the room so that it enters from the outside.

This type of container is sized in such a way that it is suitable for receiving drug capsules, or for taking from 1 mg to 1000 mg of liquid medicine, or in powder form.

As for the mode of operation of the device, it is not influenced by the material from which the device is made. It can be made of glass, ceramic, plastic or metal. In order to allow a simple making of the device, it is recommended that it be made of an easy-to-process plastic material.

In order to allow the patient a control of the inhalation, it is advantageous to make the device from a transparent, slightly colored plastic material. To avoid electrostatic charge of the device, the Venturi tube A-shaped housing may be provided with a covering layer, conductor, or a plastic material, provided with a conductive implant.

It is obvious that the device for inhalation of the medicines according to the invention can be additionally provided with auxiliary means, which, if necessary, facilitates the use of the device. Thus, for example with the chamber or housing A in the form of a Venturi tube, for example, auxiliary devices can be connected, which allow inhalation, using compressed air, gas or hot steam. On the other hand, the device may be provided, additionally, with needle-shaped or knife-like constructional parts, which are so positioned that they pierce the capsules inserted into the device.

Following are a series of constructive examples and use of devices for inhalation of drugs according to the invention.

Thus, the device for inhalation of drugs, according to fig. 1 ... 6, consists of a venturi housing A in the form of a Venturi tube, provided with an inhalation nozzle, a container holder 6 and a capture plate 10, a dosing plate 8 and a drug container 7 , which are made of thermoplastic, transparent, green ^ open material.

Housing A is composed of two cones in the shape of a cone trunk, connected together at the top, which forms a chamber b, and a widening in the form of a funnel 3. between the two layers there is an orifice, having an internal diameter of 4 mm, which forms an annular narrowing c, at the widening in the form of a funnel there is a nozzle a. It is composed of a cone 11, in the form of a cone trunk, which is limited, at the top and the bottom, by a lid plate 12, formed by segments, so as to form an opening for the nearly rectangular mouth. , 6 mm high and about 20 mm long.

In the horizontal plane of symmetry of the housing A in the form of a Venturi tube, a catch plate 10, in the form of a wedge, 2 mm thick and 17 mm long, is located in such a way that it enters 12 mm in room b and connects with side walls. This capture plate has an anterior edge, which is oblique towards the bottom and presents, at the top, a groove.

On chamber b is the holder 6 of the container, which is so formed that it connects with the upper half of the chamber b and ends, upwards, with a cylindrical washer, which is provided with an annular edge. In the holder 6 of the container is a drain hole, of

3.5 mm diameter, the center of which is at a distance from the center of the cylindrical washer and which leads to chamber b through the container holder 6 and ends in the ring narrowing c. Opposite to this drain hole, there is a hole c, which serves for retracting the support pin 13 of the dosing washer 8.

The container 7, which is used for taking the drug, is a cylinder. The upper half of the container 7 is provided with an annular edge, has a striped lateral edge. The drug container 7 has, at the bottom, a cylindrical clearance. In the recess there are five conical holes d, offset by 60 ° C, at a distance of 6 mm from the center, serving a dosing space and having a height of 8 mm and a bottom surface of 3.5 mm in diameter.

For handling the device, container 7, filled with 20 mm³ The powdered drug, in the five conical holes, is so placed in the holder 6, the pin 13 of the dosing washer 8 enters the hole e. By rotating the container 7 by 60 °, 20 mm is released.³ of the drug, which can be inhaled.

In another embodiment, according to FIG. 7 is a side view, enlarged twice, of the device described in this example.

The device consists of housing A in the form of a Venturi tube, which is provided with an inhalation nozzle a, a container 6 and a catch plate 10 and a container 1, provided with a dosing device 2, which are made of polioarbonate.

Housing A in the form of a Venturi tube, the inhalation nozzle a and the catch plate 1 have the same shapes and dimensions as the respective construction parts of the device described in the previous example.

The container holder 6 of this device differs from the one described in the previous example only by the fact that the cylindrical housing has, instead of an annular edge, an annular clearance, and instead of a hole it has a central hole f.

The container 1 of this device, provided with a dosing device 8, is composed of a container 7 for the drug, a bar 14, provided with a stirrer 15, a dosing plate 8 and a maneuver wheel 16 and a plate coverage 9.

The drug container 7 is an empty cylinder, closed at the top, with a central cylindrical hole in the lid. In this central hole there is a bar 14, provided with a stirrer 15, twisted in the form of a screw. Under the stirrer 15, the cover plate 9 is provided with a central hole, which is thus fixed in the drug container 7, until the container has, under the cover plate 9, a 6 mm wide edge, immediately below the cover plate. 9, on the bar 14, is a dosing washer 8, thick of

2.6 mm, which has two opposing holes d, 3.5 mm in diameter, located at a distance of 6 mm from the center of the dosing plate and serve as dosing spaces.

For handling the device, the container 1 filled with a powdered drug, is thus placed on the holder of the container 6, the hole of the cover plate 9 is located opposite to the hole that serves to drain, of the support 6. By rotating the wheel of maneuver 16 with 180 °, in the hole reach 25 mm³ of the drug, which can be inhaled.

According to FIG. 8 and 9, the essays represented the lateral view, enlarged twice, of the device for inhalation of drugs, in another embodiment.

in FIG. 8 shows the housing A in the form of a Venturi tube, which is provided with an inhalation nozzle and a container holder 6. This part is made of polycarbonate.

The casing A in the form of a Venturi tube, together with the inhalation nozzle a, has the same shape and size as the corresponding parts of the device described in the first embodiment.

The container holder 6 consists of a 9 mm high hollow cylinder, with an internal diameter of 12 mm, which is covered with a socket, which is thus anchored to the A venturi in the form of a Venturi tube, the center of the hollow cylinder. it is located above the annular narrowing c of housing A in the form of a Venturi tube. A metal pipe 17 is passed through the base and the chamber b, at a distance of 4 mm from the center of the cylinder, having an internal diameter of 1 mm, which enters 3.5 mm in the hollow cylinder and which is thus bent inside the chamber. b, firmly passes through the center of the annular narrowing c and ends at 1 mm above it.

in FIG. 9 shows the container 1, removed from the device. It consists of a container of medicine 7, made of polyethylene, with a capacity of 10 ml. In the neck of the drug container 7 was placed a polyethylene plug 18, which protrudes 5 mm above the edge of the container. Side of the center of the plug, a metal tube 19 passes through the plug, which comes out 3.5 mm above the plug 18.

Above the neck of the container was placed an annular super 20, made of an elastic plastic material, provided with eight cuts. This device is used to inhale a liquid medicine.

For use, the housing A in the form of a Venturi tube, is located on the container 1 arranged vertically, the empty space being filled by pressure, in the container of medicines 7 being liquid medicine. Then container 7 is triggered and the medicine in the empty space is inhaled.

The device for inhalation of drugs, described in this embodiment, is shown in FIG. 10 and 11, enlarged twice. Fig. 10 shows a side view of the device, and FIG. 11 is a plan view of the device with the soot container.

The device consists of housing A in the form of a Venturi tube, which is connected with an inhalation nozzle a, and a dosing device 2 and a container of medicines 7, which are made of a thermoplastic, transparent material.

The Venturi tube housing A is a pipe-shaped part, which, in the interior, is so narrow, 22 mm long after the previous opening, has a ring width c of 2 mm diameter. The application pipe 4 is bent upwards, as shown in FIG. 10. The end of the application pipe 4 is inclined and supports a lid 5, provided with a through hole. A support plate 6 is located on the A-shaped tube housing Venturi, so that the central axis of the support 6 is 4 mm before the ring narrowing place c. In the center of the support 6 a pin 21 has been fixed, and it protrudes above the plate. At a distance of 6 mm from the center, the support 6 has a drain hole of 3.5 mm diameter, which ends in the widening 6 of the housing 1 in the form of a Venturi tube. On the support, in front of the hole, there is a hole g, Sn which places a spiral spring with a pin 22. On the support 6 was placed, rotating, the dosing plate 8, which has the form shown in fig. 10 and 11, and a central passage hole, as well as three 3.5 mm diameter holes, offset by 120 ° each, which serve as dosing spaces, which are 6 mm away from the center. At the bottom of the dosing plate, were placed, opposite the holes drilled d, three depths h, hemispherical, removed 9 mm center, in which the pin 22 stops.

On the dosing plate is located the lid 9, rigidly connected to the pin 22, which covers the hole d above the drain hole, relative to the drug container 7.

The drug container 7 is a dose-forming part, which can be placed on the dosing plate 8. The device is used to inhale a drug in the form of a powder.

In another embodiment, the device for inhalation of drugs, shown in FIG. 12, is composed of a housing A in the form of a Venturi tube, an inhibition nozzle, a catch plate, which has the shape described by the first embodiment, on which the dosing device 2, together with the container, is located of medicines 7, with the help of a socket.

Fig. 13 is a longitudinal section through the device described in this embodiment. It is made of a transparent glass pipe. This device has a total length of 90 mm. It consists of a spherical inhalation nozzle, has an internal diameter of maximum 25 mm and a circular opening with a diameter of 20 mm. On this inhalation nozzle there is an annular narrowing c, with an inner diameter of 5 mm and above a container 1, in the form of a pipe, for receiving the drug in the form of a powder, with a length of 20 mm and an inner diameter of 6 mm minimum, which has three projections, annular, to support the capsule.

To this side is connected a chamber b, in the form of a pear, 40 mm long, and a maximum 25 mm inner diameter, which is provided at the front with a circular opening 4.

The device described may also be formed in such a way that, instead of the inhalation nozzle, described above, it presents a nozzle in another constructive form.

This device is used to inhale medicines in powder form, which are in perforated capsules 6 mm in diameter and 18 mm long and which are disposed in container 1.

In FIG. 14 is a longitudinal section represented by another embodiment of a device for inhalation of drugs. This device is made of glass. The housing consists of an inhalation nozzle, 25 mm long and 35 mm maximum inside diameter, an annular narrowing c having an internal diameter of 5 mm, as well as a chamber b, having a length of 35 mm and an inner diameter 38 mm maximum.

A third glass tube 6 mm inside diameter serves to produce a container 1 for taking the drug. A length of 13 mm from this tube remains unchanged, then the tube is made conical in the shape of a funnel and pulled through a capillary, selling an inside diameter of 1 mm and 25 mm long, which is bent at about 120 °.

This part is inserted into a hole in the housing and melted together, as the capillary hole is in the axis of symmetry and ring narrowing c.

The device described can also be made in such a way that, instead of the inhalation nozzle described above, it presents an inhalation nozzle with other constructive forms.

This device · is used for inhalation of medicines in the form of powder and liquid, which are in a storage vessel, provided with a dosing device.

In FIG. 15 represented a longitudinal section through another embodiment of the device, for inhalation of drugs. This device is made of plexiglass.

This device consists of a funnel shaped nozzle, having a length of 20 mm and an internal diameter of maximum 13 mm, which is connected with a ring-shaped narrowing c, in the form of a pipe, having a length of 4 mm and an internal diameter of 4 mm.

This ring integration c is connected in turn with a chamber b, it has a length of 30 mm and an internal diameter of maximum 25 mm. At its front, this chamber b has a circular hole of 23 mm, which is interrupted by two ribs 23, which lead symmetrically to the center of the orifice. From these ribs there is fixed an orifice, in the form of a pipe, which serves to take the medicine, which is in the axis of symmetry of the device, having a length of 41 mm and an internal diameter of 6 mm, which has, at the rear, a narrow funnel-shaped place, ending with a capillary having an internal diameter of 1 mm, thus dimensioned, enters the middle of the annular narrowing c.

This device is used to inhale the drug in powder form, which is in perforated capsules, having a length of 18 mm and a diameter of 6 mm.

In FIG. 16 s-α is a longitudinal section through another constructive variant of a device for inhalation of drugs, which is made of polyvinyl chloride. It consists of a tube 28, 60 mm long, with an outer diameter of 21 mm and an internal diameter of 19 mm. At a distance of 25 mm from one of the ends of the tube was placed a piece 24, 25 mm long, in the form of a roll, with a deep central hole of 13 mm and a diameter of 8 mm, a small central hole of 4 mm diameter, which passes through the entire device and a funnel-shaped hole at the other end.

In the large hole of the piece 24 was placed a capsule of medicine 12 mm long and 6 mm diameter. A capsule holder 25, in the form of a funnel, was then placed, and the device was closed on both sides with a plug, which holds a needle 26, having a diameter of 2 mm, which pierces the capsule.

After removing the plug, the drug in the device may be inhaled. After use, the device is discarded.

Venturi tube housing means a housing through which air flows under the same flow conditions as a gas passing through a Venturi tube.

The use of the device for inhalation of medicines according to the invention gives the following advantages:

- the Venturi tube shape of the housing and the container used to receive the drug, having a hole located in front of the diffuser portion of the housing, produce an optimal spray and drug delivery;

- allows the use not only of medicines from perforated capsules, of a certain granulation, but also allows the use of powdered, micronized or liquid medicines;

- allows an exact dosage of the drug, which no longer reaches the gastric tract, where it would produce unwanted side effects;

- does not have movable parts, which complicates the construction.