PL374221A1
Antibody inhibitors of gdf-8 and uses thereof
Abstract
The disclosure provides novel antibodies against growth and differentiation factor-8 (GDF-8), including antibody fragments, which inhibit GDF-8 activity in vitro and in vivo. The disclosure also provides methods for diagnosing, preventing or treating degenerative disorders of muscle, bone, or insulin metabolism.
Term
Term ended
Projected expiry passed 26 September 2022, 4 years ago.
- Priority
- Filed
- Published
- Projected expiry
- Today
31 members in 13 offices
Priority claims3
| Document | Office | Kind | Date |
|---|---|---|---|
| 32452801 | United States of America | P | |
| 0160324528 | – | – | – |
| US20010324528P | – | – | – |
Members31
| Document | Office | Kind | |
|---|---|---|---|
| CA2469230A1 | Canada | A1 | |
| WO03027248A2 | World Intellectual Property Organization (WIPO) | A2 | |
| WO03027248A3 | World Intellectual Property Organization (WIPO) | A3 | |
| US2003138422A1 | United States of America | A1 | |
| NO20041582L | Norway | L | |
| WO03027248A8 | World Intellectual Property Organization (WIPO) | A8 | |
| EP1438068A2 | European Patent Office (EPO) | A2 | |
| JP2005510212A | Japan | A | |
| MXPA04002834A | Mexico | A | |
| PL374221A1This record | Poland | A1 | |
| EP1438068A4 | European Patent Office (EPO) | A4 | |
| BR0212809A | Brazil | A | |
| NZ532034A | New Zealand | A | |
| ZA200402265B | South Africa | B | |
| US7320789B2 | United States of America | B2 | |
| AU2002347773B2 | Australia | B2 | |
| ZA200606082B | South Africa | B | |
| JP2009067798A | Japan | A | |
| JP4452077B2 | Japan | B2 | |
| US7731961B1 | United States of America | B1 | |
| US2011020330A1 | United States of America | A1 | |
| EP2316851A1 | European Patent Office (EPO) | A1 | |
| US8092798B2 | United States of America | B2 | |
| US2012107928A1 | United States of America | A1 | |
| US8710202B2 | United States of America | B2 | |
| EP1438068B1 | European Patent Office (EPO) | B1 | |
| PT1438068E | Portugal | E | |
| US2015024484A1 | United States of America | A1 | |
| NO336528B1 | Norway | B1 | |
| US9505831B2 | United States of America | B2 | |
| CA2469230C | Canada | C |
1 legal event, as the office reported them to INPADOC
Events
| Event | Code | |
|---|---|---|
| Decisions on refusal to grant patents (taken after the publication of the particulars of the applications)REFS | REFS |
Numbers
- Publication, DOCDB
- 374221
- Publication, EPODOC
- PL374221
- Application
- 2374221
- Application, DOCDB
- 37422102
- Application, EPODOC
- PL20020374221
Titles2
- English
- ANTIBODY INHIBITORS OF GDF-8 AND USES THEREOF
- Polish
- Inhibitory przeciwciałowe GDF-8 i ich zastosowania
Classification
- CPC, 19
- C07K16/22
- A01K2217/075
- A61K2039/505
- A61P3/02
- A61P3/04
- C07K14/475
- C07K2317/76
- A61P3/06
- A61P3/10
- A61P5/00
- A61P11/00
- A61P19/00
- A61P19/08
- A61P19/10
- A61P21/00
- A61P21/04
- A61P25/02
- A61P35/00
- A61P43/00
- IPC, 14
- C12N15 09
- A61K39 395
- A61P3 10
- A61P11 00
- A61P19 08
- A61P19 10
- A61P21 00
- A61P21 04
- A61P35 00
- C07K14 475
- C07K16 22
- C12N5 10
- C12N15 02
- C12P21 08