PL364142A1
Phenylalanine enamide derivatives possessing a cyclobutene group, for use as integrin inhibitors
Abstract
Phenylalanine enamide derivatives of formula (1) are described: wherein R1, Rx, Ry, Rz, X and V are as defined in claim 1. The compounds are able to inhibit the binding of integrins to their ligands and are of use in the prophylaxis and treatment of immuno or inflammatory disorders or disorders involving the inappropriate growth or migration of cells.
Term
Term ended
Projected expiry passed 18 January 2022, 4.7 years ago.
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64 members in 28 offices
Priority claims16
| Document | Office | Kind | Date |
|---|---|---|---|
| 0104418 | United Kingdom | A | |
| 0104418 | United Kingdom | A | |
| 0114000 | United Kingdom | A | |
| 0114000 | United Kingdom | A | |
| 0127562 | United Kingdom | A | |
| 0127562 | United Kingdom | A | |
| 0200206 | United Kingdom | W | |
| 0200206 | United Kingdom | W | |
| 010104418 | – | – | – |
| 010114000 | – | – | – |
| 010127562 | – | – | – |
| 02GB0200206 | – | – | – |
| GB20010004418 | – | – | – |
| GB20010014000 | – | – | – |
| GB20010027562 | – | – | – |
| WO2002GB00206 | – | – | – |
Members64
| Document | Office | Kind | |
|---|---|---|---|
| GB0104418D0 | United Kingdom | D0 | |
| GB0114000D0 | United Kingdom | D0 | |
| GB0127562D0 | United Kingdom | D0 | |
| CA2434666A1 | Canada | A1 | |
| WO02068393A1 | World Intellectual Property Organization (WIPO) | A1 | |
| US2002169336A1 | United States of America | A1 | |
| NO20033710D0 | Norway | D0 | |
| GB0318429D0 | United Kingdom | D0 | |
| KR20030082595A | Republic of Korea | A | |
| NO20033710L | Norway | L | |
| NO20082587L | Norway | L | |
| GB2387845A | United Kingdom | A | |
| EP1370531A1 | European Patent Office (EPO) | A1 | |
| HU0303160A2 | Hungary | A2 | |
| CZ20032259A3 | Czechia | A3 | |
| SK10322003A3 | Slovakia | A3 | |
| IL156915D0 | Israel | D0 | |
| BR0207166A | Brazil | A | |
| MXPA03006796A | Mexico | A | |
| HK1059087A1 | Hong Kong, China | A1 | |
| ZA200305372B | South Africa | B | |
| JP2004524313A | Japan | A | |
| PL364142A1This record | Poland | A1 | |
| BG107991A | Bulgaria | A | |
| CN1582276A | China | A | |
| US2005038084A1 | United States of America | A1 | |
| RU2003128105A | Russian Federation | A | |
| US6878718B2 | United States of America | B2 | |
| GB2387845B | United Kingdom | B | |
| NZ528134A | New Zealand | A | |
| AT355276T | Austria | T | |
| US7122556B2 | United States of America | B2 | |
| US2007027174A1 | United States of America | A1 | |
| EP1370531B1 | European Patent Office (EPO) | B1 | |
| RU2296753C2 | Russian Federation | C2 | |
| DE60218436D1 | Germany | D1 | |
| PT1370531E | Portugal | E | |
| EP1780201A2 | European Patent Office (EPO) | A2 | |
| EP1780201A3 | European Patent Office (EPO) | A3 | |
| DK1370531T3 | Denmark | T3 | |
| NZ540232A | New Zealand | A | |
| US2007167483A1 | United States of America | A1 | |
| AU2002225163B2 | Australia | B2 | |
| SI1370531T1 | Slovenia | T1 | |
| ES2282403T3 | Spain | T3 | |
| DE60218436T2 | Germany | T2 | |
| KR20080043407A | Republic of Korea | A | |
| CN100400513C | China | C | |
| CN101293867A | China | A | |
| KR20090005240A | Republic of Korea | A | |
| NO326554B1 | Norway | B1 | |
| KR100885780B1 | Republic of Korea | B1 | |
| US7501437B2 | United States of America | B2 | |
| JP2009057371A | Japan | A | |
| US2009105291A1 | United States of America | A1 | |
| US7531549B2 | United States of America | B2 | |
| KR100899921B1 | Republic of Korea | B1 | |
| IL156915A | Israel | A | |
| KR100905603B1 | Republic of Korea | B1 | |
| US2009186914A1 | United States of America | A1 | |
| SK286991B6 | Slovakia | B6 | |
| JP4340064B2 | Japan | B2 | |
| US7645770B2 | United States of America | B2 | |
| US7786177B2 | United States of America | B2 |
1 legal event, as the office reported them to INPADOC
Events
| Event | Code | |
|---|---|---|
| Decisions on refusal to grant patents (taken after the publication of the particulars of the applications)REFS | REFS |
Numbers
- Publication, DOCDB
- 364142
- Publication, EPODOC
- PL364142
- Application
- 2364142
- Application, DOCDB
- 36414202
- Application, EPODOC
- PL20020364142
Titles2
- English
- PHENYLALANINE ENAMIDE DERIVATIVES POSSESSING A CYCLOBUTENE GROUP, FOR USE AS INTEGRIN INHIBITORS
- Polish
- Pochodne fenyloalaninoenamidu
Classification
- CPC, 31
- C07D213/81
- C07D471/04
- C04B35/632
- C07C229/10
- C07C229/46
- C07C233/81
- C07C233/82
- C07C323/30
- C07D213/79
- C07D213/89
- C07D311/96
- C07D401/12
- C07D405/12
- C07D409/12
- C07D413/12
- C07C2601/04
- C07C2603/94
- C07C2603/96
- A61P1/04
- A61P11/06
- A61P17/00
- A61P17/02
- A61P17/06
- A61P19/02
- A61P25/00
- A61P29/00
- A61P37/00
- A61P37/06
- A61P43/00
- A61P9/00
- A61P3/10
- IPC, 27
- A61K31 198
- A61K31 4375
- A61K31 44
- A61K31 4406
- A61K31 497
- A61P3 10
- A61P9 00
- A61P17 00
- A61P17 06
- A61P19 02
- A61P25 00
- A61P29 00
- A61P37 00
- A61P37 06
- A61P43 00
- C07C229 34
- C07C229 46
- C07C233 82
- C07C321 22
- C07C323 30
- C07D213 81
- C07D213 89
- C07D401 12
- C07D405 12
- C07D409 12
- C07D413 12
- C07D471 04