Multiparticulate modified release composition
Abstract
The invention relates to a multiparticulate modified release composition that in operation delivers an active ingredient in a pulsed or bimodal manner. The multiparticulate modified release composition comprises an immediate release component and a modified release component; the immediate release component comprising a first population of active ingredient containing particles and the modified release component comprising a second population of active ingredient containing particles coated with a controlled release coating; wherein the combination of the immediate release and modified release components in operation deliver the active ingredient in a pulsed or a bimodal manner. The invention also relates to a solid oral dosage form containing such a multiparticulate modified release composition. The plasma profile achieved by the multiparticulate modified release composition is advantageous in reducing patient tolerance to the active ingredient and in increasing patient compliance by reducing dosage frequency.
Term
Term ended
Projected expiry passed 1 November 2019, 6.9 years ago.
- Priority
- Filed
- Published
- Projected expiry
- Today
214 members in 34 offices
Priority claims4
| Document | Office | Kind | Date |
|---|---|---|---|
| 10672698 | United States of America | P | |
| 10672698 | United States of America | P | |
| 9860106726 | – | – | – |
| US19980106726P | – | – | – |
Members214
| Document | Office | Kind | |
|---|---|---|---|
| CA2348871A1 | Canada | A1 | |
| CA2653839A1 | Canada | A1 | |
| WO0025752A1 | World Intellectual Property Organization (WIPO) | A1 | |
| AU1335000A | Australia | A | |
| PE20001322A1 | Peru | A1 | |
| NO20012139D0 | Norway | D0 | |
| US6228398B1 | United States of America | B1 | |
| NO20012139L | Norway | L | |
| TR200101216T2 | Türkiye | T2 | |
| EP1126826A1 | European Patent Office (EPO) | A1 | |
| ID29852A | Indonesia | A | |
| SK5992001A3 | Slovakia | A3 | |
| BR9914977A | Brazil | A | |
| CZ20011539A3 | Czechia | A3 | |
| KR20010111563A | Republic of Korea | A | |
| CN1335768A | China | A | |
| HU0104039A2 | Hungary | A2 | |
| HUP0104039A2 | Hungary | A2 | |
| IL142896D0 | Israel | D0 | |
| HU0104039A3 | Hungary | A3 | |
| HUP0104039A3 | Hungary | A3 | |
| US2002054907A1 | United States of America | A1 | |
| PL348633A1This record | Poland | A1 | |
| AR021858A1 | Argentina | A1 | |
| JP2002528485A | Japan | A | |
| NZ511442A | New Zealand | A | |
| CN1403076A | China | A | |
| CO5261536A1 | Colombia | A1 | |
| HK1050487A1 | Hong Kong, China | A1 | |
| US2003129237A1 | United States of America | A1 | |
| US2003170304A1 | United States of America | A1 | |
| AU770645B2 | Australia | B2 | |
| US6730325B2 | United States of America | B2 | |
| EP1126826A4 | European Patent Office (EPO) | A4 | |
| AU2004202078A1 | Australia | A1 | |
| US6793936B2 | United States of America | B2 | |
| RU2236847C2 | Russian Federation | C2 | |
| US2004197405A1 | United States of America | A1 | |
| US6902742B2 | United States of America | B2 | |
| MXPA01004381A | Mexico | A | |
| AU2004202078B2 | Australia | B2 | |
| AU2005247019A1 | Australia | A1 | |
| MY122159A | Malaysia | A | |
| US2006240105A1 | United States of America | A1 | |
| CA2611506A1 | Canada | A1 | |
| US2006276195A1 | United States of America | A1 | |
| WO2006130091A1 | World Intellectual Property Organization (WIPO) | A1 | |
| CA2612994A1 | Canada | A1 | |
| WO2006132752A1 | World Intellectual Property Organization (WIPO) | A1 | |
| CA2611938A1 | Canada | A1 | |
| WO2007011473A1 | World Intellectual Property Organization (WIPO) | A1 | |
| AU2006285349A1 | Australia | A1 | |
| CA2613474A1 | Canada | A1 | |
| IL142896A | Israel | A | |
| IL179379D0 | Israel | D0 | |
| WO2007027273A1 | World Intellectual Property Organization (WIPO) | A1 | |
| WO2007037790A2 | World Intellectual Property Organization (WIPO) | A2 | |
| KR20070051953A | Republic of Korea | A | |
| AU2005247019B2 | Australia | B2 | |
| US2007122481A1 | United States of America | A1 | |
| WO2007070082A1 | World Intellectual Property Organization (WIPO) | A1 | |
| US2007160675A1 | United States of America | A1 | |
| AU2007203497A1 | Australia | A1 | |
| WO2007106111A2 | World Intellectual Property Organization (WIPO) | A2 | |
| WO2007037790A3 | World Intellectual Property Organization (WIPO) | A3 | |
| AU2007260821A1 | Australia | A1 | |
| AU2007260822A1 | Australia | A1 | |
| CA2660649A1 | Canada | A1 | |
| CA2660650A1 | Canada | A1 | |
| WO2007150074A2 | World Intellectual Property Organization (WIPO) | A2 | |
| WO2007150075A2 | World Intellectual Property Organization (WIPO) | A2 | |
| CA2592727A1 | Canada | A1 | |
| NO20073289L | Norway | L | |
| KR20080002689A | Republic of Korea | A | |
| AU2007202941A1 | Australia | A1 | |
| IL184174D0 | Israel | D0 | |
| JP2008013562A | Japan | A | |
| SG138592A1 | Singapore | A1 | |
| EP1889501A1 | European Patent Office (EPO) | A1 | |
| NO20076588L | Norway | L | |
| EA200701195A1 | Eurasian Patent Organization (EAPO) | A1 | |
| MX2007016151A | Mexico | A | |
| KR100812832B1 | Republic of Korea | B1 | |
| NO20076628L | Norway | L | |
| AU2006343445A1 | Australia | A1 | |
| WO2008030209A2 | World Intellectual Property Organization (WIPO) | A2 | |
| KR20080024206A | Republic of Korea | A | |
| IL188093D0 | Israel | D0 | |
| EP1901718A1 | European Patent Office (EPO) | A1 | |
| EP1901722A1 | European Patent Office (EPO) | A1 | |
| EP1905432A1 | European Patent Office (EPO) | A1 | |
| WO2007150074A3 | World Intellectual Property Organization (WIPO) | A3 | |
| KR20080032661A | Republic of Korea | A | |
| WO2007150075A3 | World Intellectual Property Organization (WIPO) | A3 | |
| DE112006001548T5 | Germany | T5 | |
| US2008102121A1 | United States of America | A1 | |
| US2008113025A1 | United States of America | A1 | |
| US2008118556A1 | United States of America | A1 | |
| KR20080047509A | Republic of Korea | A | |
| WO2008073068A1 | World Intellectual Property Organization (WIPO) | A1 |
Numbers
- Publication, DOCDB
- 348633
- Publication, EPODOC
- PL348633
- Application
- 99348633
- Application, DOCDB
- 34863399
- Application, EPODOC
- PL19990348633
Titles
- English
- MULTIPARTICULATE MODIFIED RELEASE COMPOSITION
Classification
- CPC, 8
- A61K9/5084
- A61K9/48
- A61P11/00
- A61P25/00
- A61P25/18
- A61P31/00
- A61P43/00
- A61K31/4458
- IPC, 13
- A61K9 20
- A61K9 40
- A61K9 48
- A61K9 26
- A61K9 50
- A61K9 54
- A61K9 56
- A61K9 58
- A61K31 4458
- A61K47 32
- A61P11 00
- A61P25 00
- A61P43 00