Factor x deletion mutants and analogues thereof
Abstract
They describe factor X analogs with modification of the naturally occurring activation cleavage site of factor Xa, wherein the modification is the conversion point protease, which under natural conditions the sequence of factor X here does not split. The following are the compositions containing the Factor X analogue, and processes for their prípravy.ŕ
Term
No projected expiry on record.
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1 claim: 1 independent, 0 dependent
- 1Propre loti kjedo 1C) 'T L_C Proprietary loti kedo 1C) 'T L_C RER j RKn | 3VA NLTR [VGB l] RER j RKn|3VA NLTR[ tVGB l ] J twtfl chain (HC) J twtfl kjede (HC) OUgonukleotkipar aom ble txukl tø Kloning fXlpanWO} rXiweraiog Ongoing nucleotides became txucl th Cloning fXlpanWO} rXweraiog 0003TOW 0003TOW 0005Λ008 iQQWWto 0005Λ008 iQQWWto
8 paragraphs, as filed
(21) Search No (22) In day (24) Lopedag (41) Aim. avail.
<td>19994136</td><td>(86) Int. Entry day and</td><td></td>
<td>08/26/1999</td><td>application number</td><td>27.02.1998, PCT / AT98 / 00046</td>
<td>02/27/1998</td><td>(85) Continuation day</td><td>08/26/1999</td>
<td>27/10/1999</td><td>(30) Priority</td><td>1997.02.27, AT, 336/97</td>
(71) Seeking (72) Inventor (74) Proxy
Baxter AG, Industriestrasse 67, A-1221 Vienna, AT Michele Himmelspach, Leopoldsdorf, AT Oslo Patent Office AS, 0259 Oslo (54) Name Factor X deletion mutants and analogues thereof (57) Summary
Factor Δ analogs are described with a deletion of the amino acids Arg180 to Arg234 and a modification in the region of the amino acid sequence between Glyl73 and Argl79, preparations containing these factor XA analogs, and methods of their preparation.
64 members in 17 offices
Priority claims8
| Document | Office | Kind | Date |
|---|---|---|---|
| 33697 | Austria | A | |
| 33697 | Austria | A | |
| 9800046 | Austria | W | |
| 9800046 | Austria | W | |
| 33697 | – | – | – |
| 9800046 | – | – | – |
| AT19970000336 | – | – | – |
| WO1998AT00046 | – | – | – |
Members64
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| CA2282707A1 | Canada | A1 | |
| CA2282728A1 | Canada | A1 | |
| WO9838317A1 | World Intellectual Property Organization (WIPO) | A1 | |
| WO9838318A1 | World Intellectual Property Organization (WIPO) | A1 | |
| AU6080898A | Australia | A | |
| AU6200298A | Australia | A | |
| ATA33597A | Austria | A | |
| ATA33697A | Austria | A | |
| NO994136D0 | Norway | D0 | |
| NO994139D0 | Norway | D0 | |
| AT405516B | Austria | B | |
| AT405517B | Austria | B | |
| NO994136LThis record | Norway | L | |
| NO994139L | Norway | L | |
| EP0966536A1 | European Patent Office (EPO) | A1 | |
| CZ303199A3 | Czechia | A3 | |
| BR9807618A | Brazil | A | |
| CZ303299A3 | Czechia | A3 | |
| BR9807627A | Brazil | A | |
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| HU0000826A2 | Hungary | A2 | |
| AR012034A1 | Argentina | A1 | |
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| IL131346D0 | Israel | D0 | |
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| US6562598B1 | United States of America | B1 | |
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| US2003181381A1 | United States of America | A1 | |
| US6905846B2 | United States of America | B2 | |
| PL190734B1 | Poland | B1 | |
| EP0966536B1 | European Patent Office (EPO) | B1 | |
| AT324454T | Austria | T | |
| DE59813518D1 | Germany | D1 | |
| PL191778B1 | Poland | B1 | |
| HU225246B1 | Hungary | B1 | |
| HU225247B1 | Hungary | B1 | |
| EP1012303B1 | European Patent Office (EPO) | B1 | |
| AT340862T | Austria | T | |
| DE59813745D1 | Germany | D1 | |
| ES2263199T3 | Spain | T3 | |
| ES2273405T3 | Spain | T3 | |
| IL131171A | Israel | A | |
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| US7220569B2 | United States of America | B2 | |
| CZ298296B6 | Czechia | B6 | |
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| JP4108761B2 | Japan | B2 | |
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| NO327878B1 | Norway | B1 | |
| NO328022B1 | Norway | B1 |
1 legal event, as the office reported them to INPADOC
Events
| Event | Code | |
|---|---|---|
| Lapsed by not paying the annual feesLapsedMM1K | MM1K |
Numbers
- Publication, DOCDB
- 994136
- Publication, EPODOC
- NO994136L
- Application
- 994136
- Application, DOCDB
- 994136
- Application, EPODOC
- NO19990004136
Titles2
- Norwegian
- Faktor X delesjonsmutanter samt analoger derav
- English
- Factor X deletion mutants and analogues thereof
Classification
- CPC, 5
- C12N9/6432
- A61K38/00
- C12Y304/21006
- A61P7/00
- A61P7/04
- IPC, 15
- A61K38 00
- C12N15 09
- A61K38 36
- A61K38 46
- A61K38 48
- A61P7 00
- A61P7 04
- C07K14 475
- C12N1 15
- C12N1 19
- C12N1 21
- C12N5 10
- C12N9 64
- C12N15 57
- C12P21 02