NO20072013L

Self-gelling alginate systems and uses thereof

Abstract

Kit and compositions for preparing an alginate gel are disclosed. The kits and compositions include soluble alginate and insoluble alginate / gelling ion particles. Methods of dispensing a self-gelling alginate dispersion are disclosed. The methods include forming a dispersion of insoluble alginate / gelling ion particles in a solution containing soluble alginate, and dispensing the dispersion whereby the dispersion forms an alginate gel matrix. The methods may include dispensing the dispersion into the body of an individual. An alginate gel having a thickness of more than 5 mm and a homogeneous alginate matrix network and homogeneous alginate gels free from one or more of: sulphates citrates, phosphates, lactates, EDTA or lipids is disclosed. Implantable devices comprising a homogeneous alginate gel coating are disclosed.

Term

No projected expiry on record.

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1 claim: 1 independent, 0 dependent

  1. 1
    The methods may include dispensing the dispersion into the body of an individual. An alginate gel having a thickness of more than 5 mm and a homogeneous alginate matrix network and homogeneous alginate gels free of one or more of:sulphates citrates, phosphates, lactates, EDTA or lipids is disclosed. Implantable devices comprising a homogeneous alginate gel coating are disclosed. Methods for improving the viability of pancreatic islets, or other cellular aggregates or tissues, after isolation and during storage and transport are set forth.