Iontophoretic delivery of rotigotine for the treatment of parkinson's disease
Abstract
Using a composition comprising rotigotine and at least one chloride salt in a concentration of 1 to 140 mmol / l, where the composition has a pH of 4-6.5 in a lontophoretic device for treating Parkinson's disease, it was possible to achieve a rotigotine flux. over the human stratum corneum which was higher than that previously obtained with conventional passive diffusion systems.
Term
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1 claim: 1 independent, 0 dependent
- 1Sammendrag Summary Using a composition comprising rotigotine and at least one chloride salt at a concentration of 1-140 mmol / l, where the composition has a pH of 4-6.5 in an iontophoretic device for treating Parkinson's disease, it was possible to achieve a rotigotine flux. over the human stratum corneum that was higher than that previously achieved with conventional passive diffusion systems. Ved å benytte en sammensetning som omfatter rotigotin og minst ett kloridsalt i en konsentrasjon på 1-140 mmol/1, hvor sammensetningen har en pH på 4-6,5 i en iontoforetisk anordning for behandling av Parkinsons sykdom var det mulig å oppnå en rotigotinfluks over det humane stratum comeum som var høyere enn den som tidligere ble oppnådd med konvensjonelle passive diffusjonssystemer.
6 paragraphs, as filed
<td>(86)</td><td>Date of entry and application no</td><td>2003.11.21 PCT / ep03 / 13111</td>
<td>(85)</td><td>Videreføringsdag</td><td>2005.06.16</td>
<td>(30)</td><td>Priority</td><td>2002.12.02, EP, 02026871</td>
10-Nobel-Strasse 10.40789 MONHEIM, DE-Wagner Strasse 2,40789 MONHEIM, DE
Johanna Aaltje Bouwstra, Triangelweg 13,2992GR BARENDRECHT, NL Gai Ling Li, 103 Kings Road, HA29LD HARROW, MIDDLESEX, GB Akhmad Kharis Nugroho, Gerrit Doustraat 1A, 2311XM LEIDEN, NL (74) Fullmantig Onsagers AS,
PO Box 6963 St Olav's Square, 0130 OSLO, NO (54) Name Iontophoretic delivery of rotigotine for the treatment of Parkinson's disease
48 members in 24 offices
Priority claims8
| Document | Office | Kind | Date |
|---|---|---|---|
| 02026871 | European Patent Office (EPO) | A | |
| 02026871 | European Patent Office (EPO) | A | |
| 0313111 | European Patent Office (EPO) | W | |
| 0313111 | European Patent Office (EPO) | W | |
| 02026871 | – | – | – |
| EP20020026871 | – | – | – |
| PCTEP0313111 | – | – | – |
| WO2003EP13111 | – | – | – |
Members48
| Document | Office | Kind | |
|---|---|---|---|
| EP1426049A1 | European Patent Office (EPO) | A1 | |
| CA2505040A1 | Canada | A1 | |
| US2004116537A1 | United States of America | A1 | |
| WO2004050083A1 | World Intellectual Property Organization (WIPO) | A1 | |
| AU2003294718A1 | Australia | A1 | |
| HK1065706A1 | Hong Kong, China | A1 | |
| EP1426049B1 | European Patent Office (EPO) | B1 | |
| AT295726T | Austria | T | |
| ATE295726T1 | Austria | T1 | |
| NO20052959LThis record | Norway | L | |
| DE60204229D1 | Germany | D1 | |
| MXPA05005462A | Mexico | A | |
| DK1426049T3 | Denmark | T3 | |
| KR20050086886A | Republic of Korea | A | |
| EP1567146A1 | European Patent Office (EPO) | A1 | |
| SI1426049T1 | Slovenia | T1 | |
| ES2239196T3 | Spain | T3 | |
| PT1426049E | Portugal | E | |
| BR0316947A | Brazil | A | |
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| RU2005114749A | Russian Federation | A | |
| DE60204229T2 | Germany | T2 | |
| PL377575A1 | Poland | A1 | |
| HK1079108A1 | Hong Kong, China | A1 | |
| JP2006514937A | Japan | A | |
| EP1567146B1 | European Patent Office (EPO) | B1 | |
| AT342719T | Austria | T | |
| ATE342719T1 | Austria | T1 | |
| ZA200503750B | South Africa | B | |
| DE60309203D1 | Germany | D1 | |
| PT1567146E | Portugal | E | |
| DK1567146T3 | Denmark | T3 | |
| SI1567146T1 | Slovenia | T1 | |
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| DE60309203T2 | Germany | T2 | |
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| RU2339372C2 | Russian Federation | C2 | |
| IL168387A | Israel | A | |
| US7632859B2 | United States of America | B2 | |
| RU2008121750A | Russian Federation | A | |
| CY1106256T1 | Cyprus | T1 | |
| KR101168431B1 | Republic of Korea | B1 | |
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| RU2478383C2 | Russian Federation | C2 | |
| NO335491B1 | Norway | B1 | |
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1 legal event, as the office reported them to INPADOC
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|---|---|---|
| Lapsed by not paying the annual feesLapsedMM1K | MM1K |
Numbers
- Publication, DOCDB
- 20052959
- Publication, EPODOC
- NO20052959L
- Application
- 2959
- Application, DOCDB
- 20052959
- Application, EPODOC
- NO20050002959
Titles2
- Norwegian
- Iontoforetisk levering av rotigotin for behandling av Parkinsons sykdom
- English
- Iontophoretic delivery of rotigotine for the treatment of Parkinson's disease
Classification
- CPC, 5
- A61K31/381
- A61K9/0009
- A61P25/00
- A61P25/16
- A61K47/00
- IPC, 4
- A61K9 00
- A61K31 381
- A61K47 00
- A61P25 00