NO20051985L

Indazoles, benzothiazoles, and benzoisothiazoles, and preparation and uses thereof

Abstract

The present invention relates generally to the field of ligands for nicotinic acetylcholine receptors (nAChR), activation of nAChRs, and treatment of disease states associated with defective or malfunctioning nicotinic acetylcholine receptors, particularly in the brain. Furthermore, the invention relates to novel compounds (indazoles and benzothiazoles) which act as ligands for the α7-nAChRound type, methods of preparing such compounds, compositions containing such compounds, and methods of use thereof.

Term

No projected expiry on record.

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1 claim: 1 independent, 0 dependent

  1. 1
    Den foreliggende oppfinnelse vedrører generelt området ligander for nikotinacetylkolinreseptorer (nAChR), aktivering av nAChR-er og behandling av sykdomstilstander forbundet med defekte eller dårlig virkende nikotinacetylkolinreseptorer, spesielt i hjernen. Videre vedrører oppfinnelsen nye forbindelser (indazoler og benzotiazoler) som virker som ligander for a7-nAChRundertypen, fremgangsmåter for fremstilling av slike forbindelser, preparater som inneholder slike forbindelser, og fremgangsmåter for anvendelse derav.