Assessment of human papilloma virus-related disease

A method for detecting induced HPV infected with HPV patient comprising the steps of cellular transformation: - measuring at least two levels of mRNAs expressed HPV from a sample collected from said patient, wherein said mRNAs They comprise a first RNA selected from the group consisting of E6 mRNA and E7 mRNA and a second RNA selected from the group consisting of E2 mRNA and L1 mRNA; - Determining expression level of E6 and / or E7 and expression level of E2 and / or L1 such that a ratio of E6 and / or E7 is determined to L1 and / or E2, wherein a ratio greater than 2 it is indicative of HPV-induced cell transformation risk of neoplasia.