NO20002444L
2-Phenyl-substituited Imidazotriazinones as Phoshodiesterase Inhibitors
Abstract
The invention relates to 2-phenyl imidazotriazinones substituted with short, unbranched alkyl radicals in position 9 according to the general formula (I). Said 2-phenyl substituted imidazotriazinones are produced from the corresponding 2-phenyl imidazotriazinones by chlorosulfurization and the subsequent reaction with the amines. These compounds inhibit phosphodiesterases that metabolize cGMP and are suitable for use as agents active in medicines to treat cardiovascular and cerebrovascular diseases and / or diseases of the urogenital system, especially for the treatment of erectile dysfunction.
Term
No projected expiry on record.
- Priority
- Filed and published
- Today
125 members in 49 offices
Priority claims16
| Document | Office | Kind | Date |
|---|---|---|---|
| 19750085 | Germany | A | |
| 19750085 | Germany | A | |
| 19812462 | Germany | A | |
| 19812462 | Germany | A | |
| 19840289 | Germany | A | |
| 19840289 | Germany | A | |
| 9806910 | European Patent Office (EPO) | W | |
| 9806910 | European Patent Office (EPO) | W | |
| 9806910 | – | – | – |
| 19750085 | – | – | – |
| 19812462 | – | – | – |
| 19840289 | – | – | – |
| DE1997150085 | – | – | – |
| DE1998112462 | – | – | – |
| DE1998140289 | – | – | – |
| WO1998EP06910 | – | – | – |
Members125
| Document | Office | Kind | |
|---|---|---|---|
| HN1998000175A | Honduras | A | |
| SV1998000135A | El Salvador | A | |
| CA2309332A1 | Canada | A1 | |
| CA2395558A1 | Canada | A1 | |
| DE19750085A1 | Germany | A1 | |
| WO9924433A1 | World Intellectual Property Organization (WIPO) | A1 | |
| ZA9810297B | South Africa | B | |
| AU1558799A | Australia | A | |
| DE19812462A1 | Germany | A1 | |
| PE131799A1 | Peru | A1 | |
| DE19840289A1 | Germany | A1 | |
| UY25671A1 | Uruguay | A1 | |
| GT199800183A | Guatemala | A | |
| DK200000766A | Denmark | A | |
| FI20001086A | Finland | A | |
| NO20002444D0 | Norway | D0 | |
| NO20002444LThis record | Norway | L | |
| NO20021714L | Norway | L | |
| SE0001745D0 | Sweden | D0 | |
| SE0001745L | Sweden | L | |
| GB0010974D0 | United Kingdom | D0 | |
| TR200001338T2 | Türkiye | T2 | |
| GB2346877A | United Kingdom | A | |
| DE19881732D2 | Germany | D2 | |
| BR9812785A | Brazil | A | |
| CZ20001759A3 | Czechia | A3 | |
| EP1049695A1 | European Patent Office (EPO) | A1 | |
| ID25871A | Indonesia | A | |
| CO4980861A1 | Colombia | A1 | |
| LU90561B1 | Luxembourg | B1 | |
| CN1278822A | China | A | |
| AR013759A1 | Argentina | A1 | |
| PL340400A1 | Poland | A1 | |
| SK7092000A3 | Slovakia | A3 | |
| KR20010031944A | Republic of Korea | A | |
| HRP20000292A2 | Croatia | A2 | |
| IL135462D0 | Israel | D0 | |
| EE200000291A | Estonia | A | |
| HK1031730A1 | Hong Kong, China | A1 | |
| UY25246A1 | Uruguay | A1 | |
| BG104406A | Bulgaria | A | |
| NZ504436A | New Zealand | A | |
| AU738675B2 | Australia | B2 | |
| HU0100394A2 | Hungary | A2 | |
| HUP0100394A2 | Hungary | A2 | |
| JP2001522851A | Japan | A | |
| GB2346877B | United Kingdom | B | |
| EP1174431A2 | European Patent Office (EPO) | A2 | |
| EP1174431A3 | European Patent Office (EPO) | A3 | |
| DE19881732C1 | Germany | C1 | |
| EP1049695B1 | European Patent Office (EPO) | B1 | |
| AT213246T | Austria | T | |
| ATE213246T1 | Austria | T1 | |
| DE59803108D1 | Germany | D1 | |
| US6362178B1 | United States of America | B1 | |
| NO20021714D0 | Norway | D0 | |
| DK1049695T3 | Denmark | T3 | |
| UA46166C2 | Ukraine | C2 | |
| HU0100394A3 | Hungary | A3 | |
| HUP0100394A3 | Hungary | A3 | |
| ECSP024267A | Ecuador | A | |
| SI1049695T1 | Slovenia | T1 | |
| PT1049695E | Portugal | E | |
| IN188419B | India | B | |
| ES2172945T3 | Spain | T3 | |
| CA2309332C | Canada | C | |
| JP2002348290A | Japan | A | |
| TW513431B | Taiwan Province of China | B | |
| JP3356428B2 | Japan | B2 | |
| US6566360B1 | United States of America | B1 | |
| NO314940B1 | Norway | B1 | |
| CN1123573C | China | C | |
| ES2194567A1 | Spain | A1 | |
| KR20040014591A | Republic of Korea | A | |
| SE522809C2 | Sweden | C2 | |
| US2004067945A1 | United States of America | A1 | |
| KR100430355B1 | Republic of Korea | B1 | |
| CH693954A5 | Switzerland | A5 | |
| FI113772B | Finland | B | |
| CN1508137A | China | A | |
| AR035972A2 | Argentina | A2 | |
| ES2194567B1 | Spain | B1 | |
| TWI229081B | Taiwan Province of China | B | |
| US2005070541A1 | United States of America | A1 | |
| HK1067124A1 | Hong Kong, China | A1 | |
| US6890922B2 | United States of America | B2 | |
| CU23063A3 | Cuba | A3 | |
| RU2260593C2 | Russian Federation | C2 | |
| HRP20020585A2 | Croatia | A2 | |
| KR100548120B1 | Republic of Korea | B1 | |
| IL135462A | Israel | A | |
| US2006189615A1 | United States of America | A1 | |
| US7122540B2 | United States of America | B2 | |
| EE04781B1 | Estonia | B1 | |
| CA2395558C | Canada | C | |
| PL194801B1 | Poland | B1 | |
| BG65257B1 | Bulgaria | B1 | |
| US7314871B2 | United States of America | B2 | |
| US2008113972A1 | United States of America | A1 | |
| HRP20000292B1 | Croatia | B1 |
Showing 100 of 125
2 legal events, as the office reported them to INPADOC
Over the term
Point at a mark for the eventEvents
| Event | Code | |
|---|---|---|
| Patent expiredExpiredMK1K | MK1K | |
| Change of the owner's name or address (par. 44 patent law, par. patentforskriften)CHAD | CHAD |
Numbers
- Publication, DOCDB
- 20002444
- Publication, EPODOC
- NO20002444L
- Application
- 2444
- Application, DOCDB
- 20002444
- Application, EPODOC
- NO20000002444
Titles2
- Norwegian
- 2-fenyl-substituerte imidazotriazinoner som fosfodiesteraseinhibitorer
- English
- 2-phenyl-substituted imidazotriazinones as phosphodiesterase inhibitors
Classification
- CPC, 16
- C07D487/04
- A61K31/53
- C07F9/6561
- A61P11/08
- A61P13/00
- A61P13/02
- A61P13/08
- A61P13/10
- A61P15/00
- A61P15/10
- A61P43/00
- A61P9/00
- A61P9/06
- A61P9/08
- A61P9/10
- A61P9/12
- IPC, 22
- A61K31 00
- A61K31 53
- A61K31 5375
- A61K31 5377
- A61K31 541
- A61K31 55
- A61K31 551
- A61K31 662
- A61P9 00
- A61P9 10
- A61P11 08
- A61P13 02
- A61P13 08
- A61P13 10
- A61P15 00
- A61P15 10
- A61P43 00
- C07D
- C07D487 04
- C07D491 113
- C07D519 00
- C07F9 6561