NO20002444L

2-Phenyl-substituited Imidazotriazinones as Phoshodiesterase Inhibitors

Abstract

The invention relates to 2-phenyl imidazotriazinones substituted with short, unbranched alkyl radicals in position 9 according to the general formula (I). Said 2-phenyl substituted imidazotriazinones are produced from the corresponding 2-phenyl imidazotriazinones by chlorosulfurization and the subsequent reaction with the amines. These compounds inhibit phosphodiesterases that metabolize cGMP and are suitable for use as agents active in medicines to treat cardiovascular and cerebrovascular diseases and / or diseases of the urogenital system, especially for the treatment of erectile dysfunction.

Term

No projected expiry on record.

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Priority claims
DocumentOfficeKindDate
19750085GermanyA
19750085GermanyA
19812462GermanyA
19812462GermanyA
19840289GermanyA
19840289GermanyA
9806910European Patent Office (EPO)W
9806910European Patent Office (EPO)W
9806910–––
19750085–––
19812462–––
19840289–––
DE1997150085–––
DE1998112462–––
DE1998140289–––
WO1998EP06910–––

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