Nova Patents
LU91119I2

Novel inhibitors of thrombin

Abstract

This invention relates to novel biologically active molecules which bind to and inhibit thrombin. Specifically, these molecules are characterized by a thrombin anion-binding exosite association moiety (ABEAM); a linker portion of at least 18 ANGSTROM in length; and a thrombin catalytic site-directed moiety (CSDM). This invention also relates to compositions, combinations and methods which employ these molecules for therapeutic, prophylactic and diagnostic purposes.

Term

Term ended

Projected expiry passed 29 October 2024, 1.9 years ago.

  1. Priority
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  3. Published
  4. Projected expiry
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76 members in 23 offices

This recordMember, by publication datePriority claim13 more offices are in the list below

Priority claims9

Priority claims
DocumentOfficeKindDate
39548289United States of AmericaA
39548289United States of AmericaA
54938890United States of AmericaA
54938890United States of AmericaA
9004642United States of AmericaW
9004642United States of AmericaW
US19890395482–––
US19900549388–––
WO1990US04642–––

Members76

Family members, oldest first
DocumentOfficeKind
CA2065150A1CanadaA1
WO9102750A1World Intellectual Property Organization (WIPO)A1
AU6284190AAustraliaA
NO920616D0NorwayD0
NO920616LNorwayL
HU9200473D0HungaryD0
EP0489070A1European Patent Office (EPO)A1
CA2079778A1CanadaA1
WO9213952A1World Intellectual Property Organization (WIPO)A1
HUT60285AHungaryA
MX9203194AMexicoA
MX9203196AMexicoA
KR920702372ARepublic of KoreaA
AU1362192AAustraliaA
FI924503AFinlandA
NO923889D0NorwayD0
NO923889LNorwayL
JPH04507253AJapanA
HU9203500D0HungaryD0
EP0529031A1European Patent Office (EPO)A1
US5196404AUnited States of AmericaA
US5240913AUnited States of AmericaA
JPH05506252AJapanA
TW222642BTaiwan Province of ChinaB
HUT65675AHungaryA
AU652125B2AustraliaB2
AU659828B2AustraliaB2
US5425936AUnited States of AmericaA
US5433940AUnited States of AmericaA
JPH0768141B2JapanB2
HU211158A9HungaryA9
BG60759B2BulgariaB2
EP0489070B1European Patent Office (EPO)B1
US5514409AUnited States of AmericaA
AT137246TAustriaT
ATE137246T1AustriaT1
DE69026715D1GermanyD1
ES2086411T3SpainT3
DK0489070T3DenmarkT3
US5196404B1United States of AmericaB1
DE69026715T2GermanyT2
NZ241557ANew ZealandA
BG61243B2BulgariaB2
US5691311AUnited States of AmericaA
BG61670B2BulgariaB2
HK1001562A1Hong Kong, ChinaA1
FI102183BFinlandB
FI102183B1FinlandB1
HK1005995A1Hong Kong, ChinaA1
KR100199534B1Republic of KoreaB1
CA2065150CCanadaC
EP0529031B1European Patent Office (EPO)B1
AT193325TAustriaT
ATE193325T1AustriaT1
KR100259759B1Republic of KoreaB1
DE69231081D1GermanyD1
DK0529031T3DenmarkT3
ES2149170T3SpainT3
HU218831BHungaryB
GR3034257T3GreeceT3
DE69231081T2GermanyT2
SG79180A1SingaporeA1
NO310294B1NorwayB1
CA2079778CCanadaC
NO315710B1NorwayB1
NO2004008I1NorwayI1
LU91119I2This recordLuxembourgI2
NL300162I1Netherlands (Kingdom of the)I1
NL300162I2Netherlands (Kingdom of the)I2
FI20050027AFinlandA
DE122004000042I1GermanyI1
EP0529031B9European Patent Office (EPO)B9
DE122004000042I2GermanyI2
NO2004008I2NorwayI2
FI120348BFinlandB
FI120690BFinlandB