Medical diagnostic system

Description: TECHNICAL FIELD [Detailed description of the invention]

【0001】

[Industrial application field]

The present invention relates to a medical diagnostic system, and more particularly to a glucose medical monitor diagnostic system that obtains blood or blood components as a sample and analyzes them to give specific indications regarding blood status. The present invention relates to a portable pocket-type medical diagnostic system with a battery, which detects accumulated blood glucose and is used for diabetes treatment, and includes a disposable diagnostic reagent unit and a disposable lancet.

【0002】

[Conventional technology]

Conventional blood glucose measuring devices operate on the principle of taking blood from an individual by many methods such as by a needle or a lansing device. That is, whether the individual unit containing the chemical reagent is covered with blood, the chemical reaction is carried out for about 60 seconds, the blood is wiped or removed from the unit, and the unit covered with blood is measured with a blood glucose meter. , A visual comparison was made with respect to the color standard.

【0003】

In addition, although many blood glucose measuring devices have been commercially available, most of the devices have a large shape and are not easy to carry in a pocket. These appliances were typically housed in large handbags or individual purses, or placed in home bathrooms or bedrooms, or on counters or tables.

【0004】

A conventional medical device that detects blood glucose is a unit that holds a needle or lance that extracts blood from an individual's body and a chemical reagent for blood to cause a chemical reaction with blood glucose to change the color. It was necessary for each individual to obtain a blood glucometer that reads the color change that indicates the blood glucose level. Blood glucose levels measured by a glucometer are read from a unit holding a chemical reagent for blood through a medical diagnostic system using a reflexometer based on the known principle of glucose oxidation.

【0005】

Some monitor / reagent unit systems currently on the market have multiple sequential steps that the patient must use at precise time intervals. However, each step is susceptible to patient error. As with most monitors, monitors are regularly identified against known color criteria, and the unit is immersed in a solution of interest with known glucose content, and then visually and again identified against color criteria. It is the patient's responsibility to verify the effectiveness of the reagent units and methods by comparing color changes using. Traditional systems of these types are, of course, subject to human error.

【0006】

The procedure for obtaining accurate results from the time when a drop of blood is placed on the reagent unit pad to the time when the color change of the pad is read by the glucose monitor is described here.

【0007】

The patient punctures himself with a lancet. Try to squeeze a drop of blood onto the surface of the skin. The resulting blood is then carefully placed on the reagent pad to completely and reliably cover the pad to prevent contamination and prevent the patient's fingers from touching it. When the sample is applied to the surface of the reagent pad, the patient must press the timer on the monitor. At the end of the timer time, the patient must carefully wipe and wash the unit. In addition, for most units, the patient must place the reaction reagent unit in the monitor and press the test button or close the hatch to obtain results. Conventionally, commercially available equivalent reagent units or monitors require accurate time intervals and require operator intervention to perform in a given sequence. Also, conventional monitors are susceptible to operator errors, sequence errors, timing errors and technical errors.

【0008】

Conventional reagent units are more susceptible to contamination, which affects measurement accuracy.

【0009】

This was granted to the assignee of the invention on November 29, 1988 and is disclosed in US Pat. No. 4,787,398 entitled "Glucose Medical Surveillance System".

【0010】

The present invention includes a wearable disposable lancet, a reagent test device for blood glucose, a unit for holding a chemical reagent, and a wick for transferring blood to a blood detection reagent, thereby reading the glucose level of blood. By providing a handy type pocket type blood glucose monitor, the conventional drawbacks are eliminated.

【0011】

In view of the shortcomings of the prior art described above, the present invention is capable of detecting and measuring selected chemical reagents or chemicals used by health professionals and / or patients for the purpose of diagnosing and / or treating a sick person. A general purpose is to provide a diagnostic system using a battery that is portable and can be attached to a shirt. The use of this system is not limited to humans with respect to glucose sampling in blood. This system may be applied to veterinary animals and can also be used in industrial fields such as the measurement of glucose in grapes in the wine industry. Medical applications include, for example, insulin-dependent and non-insulin-dependent diabetes mellitus for the measurement of glucose in serum, plasma and / or whole blood. The particular quantity to be measured is glucose via reflection, absorption or potentiometric measurements by electronic circuits, although other quantities can be measured.

【0012】

[Example]

FIG. 1 is a perspective view of a portable pocket type glucose medical diagnostic system 10. The system 10 includes a disposable diagnostic reagent unit 12, which is shown in FIG. 1 and will be described in particular detail with reference to FIG. 4 below. Externally visible elements of the system 10 include front and rear housings 16 and 18, which include electromechanical structures, respectively, and a battery case 20 and a battery cover 22, as described in detail later.

【0013】

The LCD or similar visible reader 24 displays glucose levels, time, battery status, stored values in memory and other mode operations, as described in detail later.

【0014】

Conductive rubber keypad buttons 26 and 28 are located adjacent to the LCD reader 24. An actuating button 30 and a release button 32 are located on the upper side of the glucose medical monitor system 10 to perform subsequent cock operation and release of the firing (fire) mechanism, as described in detail later with reference to the figure.

【0015】

FIG. 2 is a perspective view of the portable pocket-type glucose medical diagnostic system 10 in which all numbers correspond to the elements already described. The integral and rotatable protective dust cover 34 is equipped with an internally mounted color reference identification unit 36, which swivels over the pivot blocks 38a, 38b of FIG. 8 and has the same contours as the front housing 16 and the rear housing 18. have. As shown in FIG. 8, the dust cover 34 includes a rectangular frame 39 for accommodating the internally mounted color reference color identification unit 36. Members 40 and 42 extend vertically from the inside of the dust cover 34, with the upper ends of the rear and front housings 16 and 18, respectively latching against catches 44 and 46. The vertical guide bars 48 and 50 at the ends of the rear and front housings 18 and 16 are aligned along the outer surfaces of the latches 40 and 42 and aligned with the ends of the cases 18 and 16 coupled with the dust cover 34. A rectangular frame 39 accommodating the color reference identification unit 36 is arranged in a rectangular hole 52 between the vertical end bars 54 and 56 at the ends of the rear and front housings 18 and 16, respectively. The optical window 58 is aligned with the rectangular hole 52 and is further aligned with the color reference identification unit when the dust cover 34 is rotated and latched in the closed position.

【0016】

A clip 60 having a square mounting pad 62 frictionally engages a correspondingly sized hole 64 in the rear housing 18.

【0017】

FIG. 3 is a perspective view of the portable pocket-type glucose medical diagnostic system 10 in which all numbers correspond to the elements already shown.

【0018】

The battery cover 22 has a back surface 22a and a side surface 22b between the upper and lower curved surfaces 22c and 22d. The upper and lower curved surfaces 22c, 22d include end latch members 22e and 22f for stepped engagement with the battery cover 22 within the battery case 20. The members 22a, 22b, 22c and 22d of the battery cover 22 form a supporting member that accommodates a plurality of batteries 66a to 66n. The battery cover 22 and the batteries 66a to 66n engage in the battery case 20. The batteries 66a to 66n are connected as described in detail later with reference to FIG.

【0019】

FIG. 4 is a perspective view of a portable pocket-type glucose medical diagnostic system 10 having a disposable diagnostic reagent unit 12 and a disposable lancet 14, all numbers corresponding to the elements already shown.

【0020】

The disposable lancet 14 is loaded into the launch mechanism assembly 68 of FIG. 5 through an orifice 68. Orifice 68s are arranged below fastening members 44 and 46, between bars 48 and 50 of guide 4, and further within the ends of the front and rear housings 16 and 18. After the disposable lancet 14 is loaded through the orifice 68, the disposable diagnostic reagent unit 12 is mounted between the guide bars 48 and 50 in front of the orifice 68 and the fastening members 44 and 46, behind the vertical end bars 54 and 56. Be entered. The disposable diagnostic reagent pad 12 includes a hole 70, a reagent pad 72, and windows 74 and 76 for identifying the reagent pad 72 immersed in blood by internal electronic observation, which will be described in detail later. The holes 70 of the disposable diagnostic reagent unit are aligned with the lancet needle, and the windows 74 and 76 are aligned with the optical window 58 for electronic observation.

【0021】

FIG. 5 is a perspective exploded view of the portable pocket-type glucose medical diagnostic system 10 in which all numbers correspond to the elements already shown.

【0022】

The front housing 16 has an open notch 78a, a spring storage channel 80, a release button spring 82 provided between the spring storage channel 80 and the release button 32, and a horizontally aligned launch mechanism track. Member 84, spring seat 85 between this launch mechanism track member 84 and the upper part of the housing 16, optical head track member 86, side spacer bars 88, 90, switch mounting members 92a, 92b and switch mounting members 94a, 94b. I have. The slotted notch 96a and the open notch 78a are aligned along the upper internal edge of the front housing 16 and the slotted notch 96b and the open notch 78b are aligned along the upper internal edge of the rear housing 18. Arranged to allow the release button 32 to move vertically and the actuation button 30 to move horizontally. The rear housing 18 further includes a mirror and spring seat 85 and an optical headtrack member 86, such as the image elements of the launch mechanism truck member 84. The front housing 16 further comprises a piezoelectric acoustic device mount 98, a rectangular bracket 100, a mounting bracket 102 for a conductive rubber keypad 104 including buttons 26 and 28, and a pivot hole 106 at the lower end. The rear housing 18 further comprises a pivot hole 108. The pivot holes 106 and 108 of the housings 16 and 18 accommodate the pivot blocks 38b and 38a of the dust cover 34, respectively. The clear plastic display window 110 and LCD panel 24 are aligned and secured in a rectangular bracket 100, and the foam pad 112 and elastic LCD connector 114 are aligned between the LCD panel 24 and the electronic circuit board 116. The electronic circuit board 116 is connected to the optical head 118, switches 120, 122 through a flexible cable 124. The optical spring holding device 126 and the optical spring holding device 128 are arranged behind the optical head 118, as will be described later. The optical head 118 includes a launch mechanism track member 84 and a front housing. Arranged between the optical headtrack member 86 on 16 and the corresponding track member on the rear housing 18. The launch mechanism assembly 68 is aligned between the launch mechanism track member 84 and the tops of the front and rear housings 16 and 18, and further comprises an actuator button 30, a lancet assembly 130, a launch spring 132 and a return spring 134. The switch actuator 136 is aligned between the optical headtrack member 86 and the bottom of the front housing 16 and between the corresponding members on the rear housing 18. Positive and negative battery contact assemblies 138, 140 are aligned and secured in battery case 20. The user label 142 is aligned with the label mounting hole 144 on the rear housing 18.

【0023】

FIG. 6 is a diagram showing the optical head 118 and related elements, and all the numbers correspond to the elements already shown.

【0024】

This assembly is shown on its side for illustration purposes. The LED 146, infrared LED 148 and photodiode 150 are secured in the optical head 118 by the adhesive unit 152 and tilted at a predetermined angle. The optical head has inclined surfaces 150a, 150b extending from the surface 152 of the cubic optical head 118. These slanted surfaces 150a, 150b act to assist the sliding motion of the optical head 118 when the disposable diagnostic reagent unit 12 is housed in the portable pocket-type glucose medical diagnostic system 10. The optical cover 154 extends over the optical head 118, and a thermistor 156 that fits around the optical head 118 is attached to the flexible cable 124.

【0025】

FIG. 7 is an exploded view of the launch mechanism assembly 68, all numbers corresponding to the elements already shown.

【0026】

The lancet assembly 130 forms the center of the assembly and crosses a cylinder 158, an internal lancet cavity 160, slots 162 horizontally aligned along the longitudinal direction of the top of the cylinder 158, and the cylinder 158. A return stop member is formed that includes vertically aligned slots 162, further including horizontally aligned slots 162 along the longitudinal direction, rear anti-return members 168a, 168b, and front anti-return members 170a, 170b. It intersects the actuator bars 164 and 166. The actuator button is placed on the upper part of the hammer body 172. The hammer 174 is arranged on the end of the hammer body 172. A cam 176 that activates the switch 122 extends laterally to the side of the hammer body 172. The hammer body 172 and the hammer 174 fit into the lancet cavity 160 and slide inside it. A ring-shaped spring seat 178 is formed around the cylinder 158. The firing spring 132 fits into and around the cylinder between the spring seat 178 and the hammer body 172, as shown in FIG. The return spring 134 sits between the spring seat 178 and the ends of the housings 16 and 18, as shown in FIG. The flat member 180 is aligned between the actuator button 30 and the hammer body 172. The continuous slots between the flat member 180 and the actuator button 30 overlap along slots 96a, 96b of cases 16 and 18 and act to keep the hammers aligned within the lancet cavity 160.

【0027】

FIG. 8 is a perspective view of the dust cover, all numbers corresponding to the elements already shown.

【0028】

A color reference identification strip 36 aligned with a rectangular frame 39 is particularly illustrated. The pivot blocks 38a and 38b are integrated and extend inward from the pivot bar members 184 and 186. The pivot blocks 38a and 38b, in which the opposing pivot bar members 184 and 186 extend vertically from the main body 188 toward the latches 40 and 42, engage the pivot holes 108 and 106 in FIG. 5, respectively.

【0029】

FIG. 9 is a perspective view of the battery case 20, and all numbers correspond to the elements already shown.

【0030】

The positive and negative battery contact assemblies 138 and 140 include spring contacts 138a and 140a that frictionally engage the plastic holding plate 190 at the end of the battery case 20. These spring contacts 138a and 140a abut on the batteries 66a-66n held in the battery cover 22 of FIG. Wires 192, 194 are connected to and extend from the battery contact assemblies 138, 140 and are connected to the electronic circuit board 116.

【0031】

FIG. 10 is a side view showing a partial cross section of the medical diagnostic system 10, and all numbers correspond to the elements already shown.

【0032】

The cylinder 158 with the aligned hammer body 172 is aligned between the top of the case, the launch mechanism track member 84, and the front positions of the front and rear housings 16 and 18. Both the firing spring 132 and the return spring 134 are seated against the opposing sides of the spring seat 178 of the cylinder 158. The return spring is further seated around the material surrounding the orifice 68. The firing spring sits on the spring seat 85 of the hammer body 172, slides within the range of the lancet cavity 160 in the cylinder 158, and engages the firing spring 132 when the contacts move to the right in this figure. It fits and compresses. The hammer body 172, including the cam 176, operates along the longitudinal axis by sliding the actuator button 30. Once the cylindrical body 158 is positioned longitudinally, the mounted and detented actuator bars 164 and 166 are longitudinally positioned and detent members 168a on both sides of the flat member 180 on the release button 32. , 168b and 170a, 170a, engage or batting. The spring 82 sits in the spring accommodating channel 80 with respect to the inside of the release button 32 and urges the release button 32 outward. The release button 32 also aligns with the release notches 78a, 78b, as shown in FIG. The actuator button 30 including the flat member 180 is captured in the adjacent cases 16 and 18 of the slotted notches 98a and 98b shown in FIG. The cam 176 operates the optical head switch 122 at the farthest position at the rear. The optical head 118 is aligned along the corresponding members of the side spacer bars 88, 90, the front housing 16, the optical headtrack member 86 and the rear housing 18. A spring alignment post 196 is provided on the rear side surface of the optical head, and another spring alignment post 198 is provided on the optical spring holding device 126. The spring 128 is aligned across the spring alignment posts 196, 198 and paired with the vertical end bars 56, 54, also shown in FIG. Then, the optical head 118 is slidably held at the position of the right hand of the spring. The switch actuation bar 136 is actuated against the optical head switch 120, as described in detail later.

【0033】

FIG. 11 is an electrical block diagram of the medical diagnostic system 10, where all numbers correspond to the previously described elements, as shown herein in FIGS. 12, 13, and 14.

【0034】

12 to 17 show a schematic package diagram 201 of an electric circuit, showing a digital display 202, a clock / alarm switch 203, 204, a light emitting diode 205, 206, an optical diode 207, a strip switch 208, a lance switch 209, and a piezoelectric sound generating means. 210 and batteries 211, 212 are provided. A high gain operational amplifier 213 including an operational amplifier feedback capacitor 214 and an operational amplifier pull-up resistor 215 is provided as an amplifier circuit. In addition, A / D converter 216, inverter transistor 217 for clocks for these A / D converter 216, pull-up resistor 218 for inverter 217, inverter transistor-based drive resistor 219, voltage reference regulator integrated circuit 220, voltage reference Regulator bias capacitor 224, output adjustment resistor 222, output adjustment potentiometer 223, output filter capacitor 221, voltage reference resistor 225 and voltage reference diode 226 are provided for analog-to-digital conversion and voltage reference regulator of reagent color change. Be done. Switching transistor 237 for LED205, switching transistor 238 for LED206, switching transistor-based drive resistor 273, and switching transistor-based drive resistor 274 are provided for LED switching, and LED205 brightness adjustment resistor 240 and LED206 brightness adjustment. A resistor 239 is provided for LED compensation. A capacitor 215 for the RC oscillator circuit, a resistor 247 for the RC oscillator circuit, a reset capacitor 243 and a reset resistor 244 are provided for the microprocessor 249. In addition, piezoelectric voice generator impedance load resistor 232, microprocessor pull-down resistor 241, microprocessor pull-down resistor 242, microprocessor pull-down resistor 247, microprocessor pull-down resistor 248, analog power supply. Switching transistor 271, switching transistor based drive resistor 2 70, reverse voltage protection diode 272 for timer 255, 32.768kHz crystal oscillator, timer current limiter resistor 254, crystal oscillator capacitor 256 and crystal oscillator capacitor 257 are provided for microprocessor 299. An A / D converter 233 for temperature fluctuation, a thermistor 273, and a voltage divider resistor 234 are provided for the temperature detection circuit. LCD bias resistors 261 to 164 and LCD bias capacitors 258, 260 are provided for the LCD display 202. It is provided for external connections such as serial data output enable jack 275, serial data output jack 281 and serial data clock jack 282, for personal computers. Bypass capacitors 205-253, low-battery and ultra-low-battery comparators 230 and comparator dividers 227, 229 are provided for the power circuit. EEPROM power transistors 266 and EEPROM power-based resistors 265 are provided for control power for serial EEPROMs 267 and 268. A 768kHz crystal oscillator, timer current limiter resistor 254, crystal oscillator capacitor 256 and crystal oscillator capacitor 257 are provided for microprocessor 299. An A / D converter 233 for temperature fluctuation, a thermistor 273, and a voltage dividing resistor 234 are provided for the temperature detection circuit. LCD bias resistors 261 to 164 and LCD bias capacitors 258, 260 are provided for the LCD display 202. It is provided for external connections such as serial data output enable jack 275, serial data output jack 281 and serial data clock jack 282, for personal computers. Bypass capacitors 205-253, low-battery and ultra-low-battery comparators 230 and comparator dividers 227, 229 are provided for the power circuit. EEPROM power transistors 266 and EEPROM power-based resistors 265 are provided for control power for serial EEPROMs 267 and 268. A 768kHz crystal oscillator, timer current limiter resistor 254, crystal oscillator capacitor 256 and crystal oscillator capacitor 257 are provided for microprocessor 299. An A / D converter 233 for temperature fluctuation, a thermistor 273, and a voltage dividing resistor 234 are provided for the temperature detection circuit. LCD bias resistors 261 to 164 and LCD bias capacitors 258, 260 are provided for the LCD display 202. It is provided for external connections such as serial data output enable jack 275, serial data output jack 281 and serial data clock jack 282, for personal computers. Bypass capacitors 205-253, low-battery and ultra-low-battery comparators 230 and comparator dividers 227, 229 are provided for the power circuit. EEPROM power transistors 266 and EEPROM power-based resistors 265 are provided for control power for serial EEPROMs 267 and 268.

【0035】

The operation of the electric circuit of FIGS. 12 to 16 will be described in detail here.

【0036】

LED205 is a light source that illuminates the reagent chemistry area. Reagent chemicals change color in proportion to the amount of glucose in the blood. The light from the impulse 205 is reflected by the chemical and detected by the photodiode 207. This signal is amplified by the high gain operational amplifier 213 and then sent to the analog-to-digital converter 216. The analog signal is converted to a digital signal and used by microprocessor 249. The software algorithm of microprocessor 249 processes this information and then outputs the blood glucose measurement to the liquid crystal display 202.

【0037】

LED206 illuminates the lot-to-lot indicator of the medical diagnostic system 10. It provides information to microprocessor 249 to compensate for variations in different lots of chemicals. An inter-lot indicator is used to determine if the blood is completely covered with reagent chemicals. The light reflected from the LED 206 is detected by the photodiode 207, and this signal is reflected from the LED 205 and sent to the microprocessor 249 in the same manner as the light.

【0038】

The voltage reference regulator 220 provides a reference voltage to the medical monitor system circuit. This reference voltage is used by the analog-to-digital converter 216, the low battery detection comparator 230, the temperature A / D converter 233, and to keep the LED output constant.

【0039】

Comparator 230 is used to provide low battery and ultra low battery signals to microprocessor 249. A switching transistor 271 is used to control the power to the analog circuit that is turned on only when the detection circuit of the light diode 207 is active. The crystal oscillator 255 gives the microprocessor 249 a precise clock to provide various timing functions. Switch 209 is used to initiate the blood glucose measurement sequence by the medical diagnostic system 10. Switch 208 signals microprocessor 249 to indicate when reagent unit 12 has been charged. Switches 203 and 204 are used to set the clock and four alarms of the medical diagnostic system 10. Piezoelectric voice generating means 231 gives audible voice to indicate the progress of the test or the error status. The thermistor 273 with the A / D converter 233 feeds the temperature-corrected input data to the microprocessor 249 to compensate for ambient temperature fluctuations that occur in the user's environment. EEPROMs 267 and 268 are provided to the non-volatile memory storage device for alarms, stored glucose readings and various coefficients or calculations used by microprocessor 249.

【0040】

FIG. 18 is a diagram showing the loading of the medical diagnostic system 10 and the operating mode of the reagent unit 12, all of which correspond to the elements already described.

【0041】

19-27 are diagrams showing the arrangement of elements and modes of electromechanical operation with respect to the medical diagnostic system 10, all numbers corresponding to the elements already described.

【0042】

FIG. 19 is a diagram showing the normal positions of the above elements.

【0043】

FIG. 20 is a diagram showing an actuator button pressed to the load position.

【0044】

FIG. 21 is a diagram showing a button released and locked at the load position.

【0045】

FIG. 22 is a diagram showing a lancet loaded at the load position.

【0046】

FIG. 23 is a diagram showing a button pressed to the cock position.

【0047】

FIG. 24 is a diagram showing the loaded strips.

【0048】

FIG. 25 is a diagram showing a fully expanded position during penetration.

【0049】

FIG. 26 is a diagram showing the return to the normal position after penetration.

【0050】

FIG. 27 is a diagram showing a button pressed to the take-out position for removing and taking out the rasset.

【0051】

During operation, the slide button is pressed forward. Charge the lancet into the carrier tube. Remove the cap and pull the slide button back. Open the optical cover and properly charge the reagent unit. Press your finger onto the reagent unit collector. Press the release button and squeeze your finger to get a drop of blood. Read the glucose level displayed after 90 seconds and record the result. The used reagent unit is withdrawn and dumped. Push the slide button forward, remove the used lancet, and close the optical cover.

【0052】

FIG. 25 is a diagram showing a display message generated by a microprocessor algorithm and displayed on the LCD.

【0053】

The present invention can be modified in various ways without departing from the scope disclosed in the attached drawings.

【0054】

The system can be programmed to detect color types in addition to color changes, as provided through the suggestions herein.

[Simple explanation of drawings]

[Figure 1]

It is a perspective view which shows the Example of the glucose medical monitor system.

[Figure 2]

It is a perspective view which shows the back side of the medical diagnostic system.

[Fig. 3]

It is a perspective view of the medical diagnostic system which shows the battery case.

[Fig. 4]

FIG. 3 is a perspective view of a medical diagnostic system adapted to receive a disposable lancet and a disposable diagnostic reagent strip.

[Fig. 5]

It is an exploded perspective view of a medical diagnostic system.

[Fig. 6]

It is an exploded perspective view of an optical head.

[Fig. 7]

It is an exploded perspective view of the launch mechanism assembly.

[Fig. 8]

It is a perspective view of a dust cover.

[Fig. 9]

It is a perspective view of a battery case.

[Fig. 10]

It is a side view which includes a partial cross section of a medical diagnostic system.

[Fig. 11]

It is a block diagram of a medical diagnostic system.

[Fig. 12]

It is the schematic of the electric circuit of the medical diagnostic system.

[Fig. 13]

It is the schematic of the electric circuit of the medical diagnostic system.

[Fig. 14]

It is the schematic of the electric circuit of the medical diagnostic system.

[Fig. 15]

It is the schematic of the electric circuit of the medical diagnostic system.

[Fig. 16]

It is the schematic of the electric circuit of the medical diagnostic system.

[Fig. 17]

It is the schematic of the electric circuit of the medical diagnostic system.

[Fig. 18]

It is a figure which shows the loading operation of the medical diagnostic system.

[Fig. 19]

It is a figure which shows the positioning of the element at the time of operation of a medical diagnostic system.

[Fig. 20]

It is a figure which shows the positioning of the element at the time of operation of a medical diagnostic system.

[Fig. 21]

It is a figure which shows the positioning of the element at the time of operation of a medical diagnostic system.

[Fig. 22]

It is a figure which shows the positioning of the element at the time of operation of a medical diagnostic system.

[Fig. 23]

It is a figure which shows the positioning of the element at the time of operation of a medical diagnostic system.

[Fig. 24]

It is a figure which shows the positioning of the element at the time of operation of a medical diagnostic system.

[Fig. 25]

It is a figure which shows the positioning of the element at the time of operation of a medical diagnostic system.

[Fig. 26]

It is a figure which shows the positioning of the element at the time of operation of a medical diagnostic system.

[Fig. 27]

It is a figure which shows the positioning of the element at the time of operation of a medical diagnostic system.

[Fig. 28]

It is a figure which shows the display message.

[Explanation of symbols]

10 ... Portable pocket type glucose medical diagnostic system 12 ... Disposable diagnostic reagent unit 16 ... front housing 18 ... rear housing 24 ... Visible reader 26, 28 ... Conductive rubber keypad buttons 30 ... Actuator button 32 ... release button 36 ... Color reference identification unit