Patch for bleaching tooth

Description: TECHNICAL FIELD [Detailed description of the invention]

【0001】

[Technical field to which the invention belongs]

The present invention relates to a bleaching patch for whitening teeth. Further, the present invention uses a sheet body having a barrier property as a bleaching agent when whitening teeth coloring due to eating, drinking, smoking, bacteria, etc., and is safe so that the bleaching agent does not adhere to the toothpaste other than the teeth or the inside of the oral cavity. Regarding bleaching patches.

【0002】

[Conventional technology]

Conventionally, a liquid polymer composition for whitening teeth is known as a technique for whitening teeth by removing colored substances such as food and drink, smoking, and bacteria (Japanese Patent Laid-Open No. 6-128130). In the liquid polymer composition used here, when a water-soluble cellulose polymer is mixed with an oxidizing agent and a hydroalcohol and applied to teeth, a film is formed by evaporation of the solvent, but the film continuously releases the oxidizing agent. With the liquid polymer composition that whitens teeth, it is impossible to apply it to teeth before sleeping at home, and after application, it was necessary to open the mouth for the time until the solvent evaporates, and the forming film Was difficult to remove from the teeth. In this way, conventionally, there has been a demand for a material for whitening teeth that can easily and easily remove colored substances that have colored teeth at any time in ordinary households, but none of them satisfy this requirement. ..

【0003】

Further, in Japanese Patent Application Laid-Open No. 10-17448, a sheet-like two-layer body composed of a support layer and a sticking layer in which a whitening component such as kodiic acid, a kodiate, and a kodiic acid derivative is blended in a sticking layer to be stuck on the tooth surface is formed. However, a water-insoluble polymer substance is used as a component of the support layer, and a water-soluble polymer substance is used as a component of the sticking layer, and the sticking layer is wetted with water and stuck to the teeth. It is a cellulose-based sheet, and as the water-soluble polymer substance, ethyl cellulose, cellulose acetate-based polymer, (meth) acrylic acid-based polymer, polyvinyl acetal-based polymer, etc. are used. Since it does not have a barrier property, the drug adheres to or diffuses into the toothpaste or the oral cavity during use, causing discomfort. Since the whitening ingredients, Koujiic acids, were mixed in the sticking layer and placed in an open state, they had a two-layer structure that reduced the effectiveness of the ingredients and caused deterioration.

【0004】

In addition, USP5,879,691 and USP5,891,453 are also two-layered bodies in which a gel body containing a bleaching agent is applied to a flexible support sheet, and the support sheet has a concave pocket for storing the gel body by embossing. However, the sheet coated with the gel body is difficult to handle because the gel gets dirty on the hands and gets sticky during handling, and the support sheet does not have the barrier property of bleach, so it is a toothpaste. There is a problem that the drug adheres to or spreads inside the oral cavity.

【0005】

[Problems to be Solved by the Invention]

An excellent whitening sheet must be a sheet body that has a barrier property to the chemical components contained in the sheet body in order to maintain a constant medicinal effect, and should be attached to the teeth to prevent contamination of the toothpaste and the inside of the cavity. Barrier properties are desired for the drug component face-to-face, but such a bleaching patch is not yet known. Therefore, in the present invention, the bleach gel does not get dirty or sticky on the hands during handling, and it is easy to handle, and the support sheet itself has the barrier property of the bleach, so that it can be applied to the teeth and the inside of the oral cavity. It is an object of the present invention to provide a patch for tooth bleaching, in which the drug does not adhere or diffuse, and the drug does not adhere or diffuse into the toothpaste or the oral cavity during use and does not cause discomfort.

【0006】

[Means for solving problems]

In the present invention, as a bleaching patch for tooth whitening, a pullulan film containing a bleaching agent is used as a basic layer, and a pullulan film or a synthetic resin film is appropriately provided on one or both sides of the basic layer to form a one-layer to three-layer structure. The above-mentioned problems could be solved by using the laminated body of.

【0007】

Further, in detail, the present invention is characterized by the following configuration. (1) A tooth bleaching patch that is a tooth whitening bleaching material and is a pullulan film containing a bleaching agent. (2) A tooth bleaching patch characterized in that a synthetic resin film layer having a barrier property is provided on one side of a pullulan film containing a bleaching agent. (3) A tooth bleaching patch characterized by polymerizing a pullulan film on one or both sides of a pullulan film containing a bleaching agent. (4) The tooth bleaching patch according to any one of (1) to (3) above, wherein the thickness of each layer is 10 μ to 40 μ. (5) Any of the above (1) to (4), wherein the bleaching agent contained in pullulan is a bleaching agent selected from hydrogen peroxide, urea peroxide, carbamide peroxide, and sodium peroxyborate. A patch for bleaching teeth described in Crab. (6) The tooth bleaching according to any one of (1) to (5) above, wherein the synthetic resin film of the barrier protective layer is a film selected from PE, polyurethane, nylon 6 or nylon 66. Pasting material for.

【0008】

In the bleaching attachment material of the present invention, it is appropriate to appropriately improve the barrier property of the bleaching agent, but the air permeability of various films (CC / m).²If you look at 24hr.atm), for example, Pullulan 1.3CC / m²24hr.atm, nylon 50CC / m²24hr.atm, PET200CC / m²24hr.atm, PE500CC / m²24hr.atm, PE1100CC / m²It is 24hr.atm, and the most important feature of the present invention is to utilize the barrier property of pullulan. Further, in the present invention, since the components in the gel state are not used, the components of each film layer are in the dry state, so that they are easy to handle and can be accurately attached to the surface of a predetermined tooth. In addition, when applied to teeth, the bleach does not bleed and contaminate the inside of the toothpaste or oral cavity. Therefore, it is safe without any discomfort or irritation.

【0009】

In the present invention, it is not necessary to use a gel-based adhesive component because the pullulan itself adheres to the tooth due to the water content of the tooth. For example, when a protective pullulan film or synthetic resin film is provided, there is a film layer containing pullulan containing a bleaching agent under the film layer, and since it is not an open system, the concentration of hydrogen peroxide or the like changes. The active ingredient is stabilizing. The structure of the present invention is basically a one- to three-layer structure using pullulan, and is basically the presence of a pullulan film layer containing at least a bleaching agent, and appropriately protects one or both sides of the basic layer. A pullulan layer or a synthetic resin layer is provided, and the thickness of each layer is preferably 10 μ to 40 μ. It is inconvenient to handle below 10μ. When it becomes 40μ or more, it becomes 120μ or more in a three-layer structure, and there is a sense of discomfort as a film body used for the oral cavity, and it is not suitable for use.

【0010】

As the bleaching agent contained in the pullulan film layer of the tooth bleaching patch of the present invention, one selected from hydrogen peroxide, urea peroxide, carbamide peroxide or sodium peroxyborate can be used. The concentration of the above bleaching agent can be used in the range of 1 to 10% by weight based on pullulan, but 2 to 7% by weight is particularly suitable. If the concentration of the bleaching agent contained in pullulan is 1% by weight or less, the whitening effect cannot be obtained. In addition, if it is 10% by weight or more, the skin inside the oral cavity is not used due to damage or harmfulness. When using the tooth bleaching patch of the present invention, it is essential that the pullulan film exists as a layer in contact with the teeth, and the saliva adhering to the teeth dissolves the pullulan. The bleaching agent acts to bleach the tooth surface.

【0011】

The present invention will be described in more detail by way of examples, but the configuration of the present invention is not influenced by the configuration of the examples.

【0012】

[Example 1]

A 20μ pullulan film containing 4% by weight of hydrogen peroxide and 0.1% by weight of sodium citrate is overlaid with a film made of 100% pullulan with a thickness of 40μ to form two layers, which are punched into a sticking shape on teeth and bleaching sticking material. Got The resulting patch was applied to the teeth and held for 30 minutes, then rinsed well with water. This work was done once daily and continued for 14 days. After 14 days, it was confirmed that the teeth became white and beautiful. At the time of the experiment, there was no discomfort or skin abnormality inside the oral cavity.

【0013】

[Example 2]

A 20μ pullulan film containing 5% by weight of urea peroxide and 0.2% by weight of sodium citrate is laminated between a 20μ thick pullulan 100% film and a 20μ thick PE film to form three layers of teeth. A sticking material for bleaching was obtained by punching into a sticking shape. The resulting patch was applied to the teeth and held for 30 minutes, then rinsed well with water. This work was continued once a day for 14 days. After 14 days, it was confirmed that the teeth became white and beautiful. At the time of the experiment, there was no discomfort or skin abnormality inside the oral cavity.

【0014】

[Example 3]

A 20μ pullulan film containing 4% by weight of carbamide peroxide and 0.1% by weight of sodium citrate is laminated between a film made of 100% pullulan with a thickness of 20μ and a polyurethane film with a thickness of 20μ to form three layers. A sticking material for bleaching was obtained by punching into a sticking shape. The resulting patch was applied to the teeth and held for 30 minutes, then rinsed well with water. This work was done once daily and continued for 14 days. After 14 days, it was confirmed that the teeth became white and beautiful. At the time of the experiment, there was no discomfort or skin abnormality inside the oral cavity.

【0015】

[Effect of the invention]

In the tooth bleaching patch of the present invention, pullulan adheres to the tooth due to the moisture of the tooth, so that it is not necessary to use an adhesive component by a gel body, and there is a pullulan layer containing a bleaching agent under the pullulan layer. Since it is not an open system, there is no change in concentration such as hydrogen peroxide system, and the active ingredient is stable. Since the tooth bleaching patch of the present invention is not used in the gel state, the pullulan layer containing the bleaching agent is constantly a dry sheet, which is easy to handle and accurately adheres to a predetermined tooth surface. Can be done. In addition, when it is applied to teeth, the bleach does not bleed and contaminate the inside of the toothpaste or oral cavity, so that it can be used safely without causing discomfort or irritation.