Multifunctional enzyme
Abstract
The invention relates to a multifunctional enzyme that can be derived from crustaceans or fish. The enzyme has at least one of a chymotrypsin, trypsin, elastase, collagenase and exo peptidase activity, and a molecular weight between about 20 kd and about 40 kd as determined by SDS PAGE. Preferably, the multifunctional enzyme has substantial anti cell-cell adhesion activity. Preferably, the multifunctional enzyme has substantial homology with the krill multifunctional enzyme. These enzymes are useful for treating viral infections such as herpes outbreaks, fungal, bacterial or parasitic infections, including the primary and secondary infections of leprosy, colitis, ulcers, hemorrhoids, corneal scarring, dental plaque, acne, cystic fibrosis, blood clots, wounds, immune disorders including autoimmune disease and cancer. Additionally, the invention relates to a method of purifying the multifunctional enzyme, and to a preparation of essentially purified multifunctional enzyme.
Term
Term ended
Projected expiry passed 7 August 2017, 9.1 years ago.
- Priority
- Filed and published
- Projected expiry
- Today
69 members in 26 offices
Priority claims10
| Document | Office | Kind | Date |
|---|---|---|---|
| 38554095 | United States of America | A | |
| 38554095 | United States of America | A | |
| 48682095 | United States of America | A | |
| 48682095 | United States of America | A | |
| 9601650 | United States of America | W | |
| 9601650 | United States of America | W | |
| PCTUS9601650 | – | – | – |
| US19950385540 | – | – | – |
| US19950486820 | – | – | – |
| WO1996US01650 | – | – | – |
Members69
| Document | Office | Kind | |
|---|---|---|---|
| SE9201628D0 | Sweden | D0 | |
| CA2136331A1 | Canada | A1 | |
| CA2306952A1 | Canada | A1 | |
| WO9324142A1 | World Intellectual Property Organization (WIPO) | A1 | |
| ZA933598B | South Africa | B | |
| AU4100093A | Australia | A | |
| CN1089505A | China | A | |
| NO944448D0 | Norway | D0 | |
| NO944448L | Norway | L | |
| HU9403343D0 | Hungary | D0 | |
| EP0642351A1 | European Patent Office (EPO) | A1 | |
| CZ286794A3 | Czechia | A3 | |
| HUT69989A | Hungary | A | |
| JPH08501068A | Japan | A | |
| IL117060D0 | Israel | D0 | |
| CA2212533A1 | Canada | A1 | |
| WO9624371A1 | World Intellectual Property Organization (WIPO) | A1 | |
| AU4917096A | Australia | A | |
| ZA961030B | South Africa | B | |
| SK140594A3 | Slovakia | A3 | |
| RU94046254A | Russian Federation | A | |
| AU675942B2 | Australia | B2 | |
| NO973627D0 | Norway | D0 | |
| IS4539AThis record | Iceland | A | |
| NO973627L | Norway | L | |
| EP0810875A1 | European Patent Office (EPO) | A1 | |
| BR9607506A | Brazil | A | |
| EP0824910A2 | European Patent Office (EPO) | A2 | |
| EA199700167A1 | Eurasian Patent Organization (EAPO) | A1 | |
| EP0824910A3 | European Patent Office (EPO) | A3 | |
| CZ254197A3 | Czechia | A3 | |
| EP0838213A1 | European Patent Office (EPO) | A1 | |
| CN1181018A | China | A | |
| PL324085A1 | Poland | A1 | |
| MX9706095A | Mexico | A | |
| KR19980702081A | Republic of Korea | A | |
| JPH11502102A | Japan | A | |
| HU9900338A2 | Hungary | A2 | |
| HUP9900338A2 | Hungary | A2 | |
| US5945102A | United States of America | A | |
| EP0810875A4 | European Patent Office (EPO) | A4 | |
| US5958406A | United States of America | A | |
| US6030612A | United States of America | A | |
| AU718220B2 | Australia | B2 | |
| JP2000351734A | Japan | A | |
| NZ302984A | New Zealand | A | |
| KR100290266B1 | Republic of Korea | B1 | |
| US6232088B1 | United States of America | B1 | |
| NZ503162A | New Zealand | A | |
| EP0642351B1 | European Patent Office (EPO) | B1 | |
| AT214610T | Austria | T | |
| ATE214610T1 | Austria | T1 | |
| DE69331739D1 | Germany | D1 | |
| DK0642351T3 | Denmark | T3 | |
| CN1090505C | China | C | |
| CN1090507C | China | C | |
| ES2173887T3 | Spain | T3 | |
| DE69331739T2 | Germany | T2 | |
| US2005025722A1 | United States of America | A1 | |
| CA2136331C | Canada | C | |
| EP0838213B1 | European Patent Office (EPO) | B1 | |
| AT311853T | Austria | T | |
| ATE311853T1 | Austria | T1 | |
| DE69333931D1 | Germany | D1 | |
| ES2255097T3 | Spain | T3 | |
| US2006134641A1 | United States of America | A1 | |
| DE69333931T2 | Germany | T2 | |
| JP4012665B2 | Japan | B2 | |
| US7947270B2 | United States of America | B2 |
Numbers
- Publication, DOCDB
- 4539
- Publication, EPODOC
- IS4539
- Application
- 4539
- Application, DOCDB
- 4539
- Application, EPODOC
- IS19970004539
Titles2
- Icelandic
- Fjölvirkt ensím
- English
- Multipurpose enzyme
Classification
- CPC, 22
- C12N9/6408
- A61K38/46
- C12N9/00
- C12N9/48
- C12N9/6402
- C12N9/6448
- A61K38/00
- A61P11/00
- A61P17/00
- A61P17/02
- A61P27/02
- A61P27/14
- A61P29/00
- A61P31/00
- A61P31/04
- A61P31/12
- A61P33/00
- A61P35/00
- A61P37/00
- A61P37/08
- A61P43/00
- Y02A50/30
- IPC, 26
- A61K8 96
- A61K8 98
- C12N9 14
- A61K35 56
- A61K38 00
- A61K38 43
- A61K38 48
- A61K38 55
- A61P11 00
- A61P17 00
- A61P17 02
- A61P27 02
- A61P27 14
- A61P29 00
- A61P31 00
- A61P31 04
- A61P31 12
- A61P35 00
- A61P37 00
- A61P37 08
- A61P43 00
- A61Q11 00
- C12N9 00
- C12N9 48
- C12N9 64
- C12N9 66